Clinical trials: Post-Operative Condition
Postoperative Pain
Dose-Ranging Study for Prolonged Postoperative Analgesia in Subject Undergoing Total Knee Arthroplasty
Dose-ranging study for prolonged postoperative analgesia in subjects undergoing total knee arthroplasty
- Trial name
- TKA (NCT00485693)
- Testing
- Bupivacaine HCl, SKY0402
- Where
- 9 sites in United States, Czechia
- Volunteers
- 138 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Pain, Postoperative
Continuous Erector Spinae Block Versus Continuous Paravertebral Block
Overall Aim: To evaluate the efficacy of continuous erector spinae block (ESB) versus continuous paravertebral block (PVB) for postoperative analgesia in children and adolescents undergoing surgical procedures via unilateral…
- Trial name
- NCT03768440
- Testing
- continuous erector spinae block (ESB), continuous paravertebral block (PVB), Ropivacaine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Postoperative Pain
A Retrospective Investigation of Local Anesthetic Concentrations in Femoral Nerve Block
The purpose of this study is to retrospectively compare perioperative pain relief and safety in pediatric patients who have received a femoral nerve block with varying concentrations of local anesthetic.
- Trial name
- NCT02501135
- Testing
- Femoral nerve block with ropivacaine or bupivacaine
- Volunteers
- 281 people
- Sponsor
- Giorgio Veneziano
Postoperative Nausea and Vomiting
Granisetron Transdermal Patch for Prevention of Postoperative Nausea and Vomiting
The objective of the study is to evaluate the efficacy and safety of adding transdermal preparation of granisetron (Sancuso ®) to the current postoperative nausea and vomiting (PONV) standard prophylaxis regimen with…
- Trial name
- GTPPONV (NCT02457195)
- Testing
- granisetron
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Milton S. Hershey Medical Center
Pain, Postoperative
Intraoperative Liposomal Bupivacaine vs. Bupivacaine for Total Hip Replacement Pain Management
The purpose of this study is to compare two medications currently injected intra-operatively to help decrease pain after surgery in patients undergoing a primary total hip replacement (THR).
- Trial name
- NCT03001453
- Testing
- Liposomal Bupivacaine, 0.25% Bupivacaine with epinephrine, Saline
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- American Hip Institute
Arthritis
Total vs. Reverse Shoulder Replacement: Pain Relief Two Years After Surgery
Specific Aim: To compare early postoperative pain relief in patients over the age of 70 who undergo either Total Shoulder Arthroplasty or Reverse Shoulder Arthroplasty in treatment of glenohumeral osteoarthritis.
- Trial name
- NCT01884077
- Testing
- Reverse Shoulder Arthroplasty, Total Shoulder Arthroplasty
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Washington University School of Medicine
Hernia, Ventral, Incisional Hernia
A Prospective Trial of a Bio-absorbable Mesh in Challenging Laparoscopic Ventral or Incisional Hernia Repair
The objective of this study is to collect additional data on safety, performance and effectiveness of Phasix™ ST in subjects receiving laparoscopic ventral or incisional hernia repair at high risk for surgical site occurrence…
- Trial name
- ATLAS (NCT02712398)
- Testing
- Phasix™ ST
- Where
- 16 sites in United States
- Volunteers
- 120 people
- Sponsor
- C. R. Bard
Postoperative Pain
Perioperative Use of Gabapentin To Decrease Narcotic Requirements in Spinal Fusion
Blinded study using oral gabapentin in load pre-operative (15mg/kg) and maintenance 5mg/kg three times a day (TID) for 5 days or discharge, Patient Controlled Analgesia (PCA) morphine and placebo group with similar pills, also…
- Trial name
- NCT00726999
- Testing
- Gabapentin, Morphine
- Volunteers
- 63 people
- Sponsor
- Medical College of Wisconsin
Arthropathy of Hip
Compare Epidural vs. Lumbar Plexus Analgesia After Hip Arthroplasty
The goal of this retrospective chart review is to evaluate if the implementation of lumbar plexus block placement for postoperative pain have improved conditions in the postoperative period for patients undergoing total hip…
- Trial name
- NCT02493621
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Post-operative Pain
Ibuprofen/Acetaminophen Versus Nurofen Plus® and Panadeine® Extra Dental Pain Study
The objective is to assess the efficacy and tolerability of a combination of 400 mg ibuprofen plus 1000 mg acetaminophen, 200 mg ibuprofen plus 500 mg acetaminophen compared with Nurofen Plus® and Panadeine® Extra.
- Trial name
- NCT01229449
- Testing
- Ibuprofen/acetaminophen, Ibuprofen/acetaminophen (higher dose), Nurofen Plus®
- Where
- United States
- Volunteers
- 678 people
- Sponsor
- Reckitt Benckiser LLC
Carpal Tunnel Syndrome
Preoperative Gabapentine for Carpal Tunnel
The purpose of this study was to evaluate the postoperative analgesic effect of preoperative gabapentine for carpal tunnel syndrome surgery.
- Trial name
- NCT01632215
- Testing
- Gabapentine, Sugar pill
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Cushing's Disease, Acromegaly
Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in Novartis-sponsored Studies
The purpose of this study is to allow continued use of pasireotide in patients who are on pasireotide treatment in a Novartis-sponsored study and are benefiting from the treatment as judged by the investigator.
- Conditions
- Cushing's Disease, Acromegaly, Neuroendocrine Tumors, Pituitary Tumors
- Trial name
- NCT01794793
- Testing
- Pasireotide, Cabergoline, Pasireotide LAR
- Where
- 94 sites in United States, Argentina and 26 more
- Volunteers
- 337 people
- Sponsor
- RECORDATI GROUP
Ventral Hernia
Open Versus Robotic Retromuscular Ventral Hernia Repair
The purpose of this study is to determine how the robotic retromuscular hernia repair compares to the open retromuscular hernia repair for large hernia defects in patients at higher risk of wound complications.
- Trial name
- ORREO (NCT03007758)
- Testing
- open ventral hernia repair, robotic ventral hernia repair
- Volunteers
- 101 people
- Sponsor
- Prisma Health-Upstate
Kidney Stone
Opioid Free Management After Ureteroscopy
The purpose of this research study is to compare how well two medications work to control post-operative pain.
- Trial name
- NCT03872843
- Testing
- Norco 5milligram-325milligram Tablet, Ibuprofen 400 MILLIGRAM in 1 TABLET ORAL TABLET, FILM COATED
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University Health Sciences
Nausea, Vomiting
Comparison of Oral Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting
Recent evidence suggests multiple drug therapy is superior to single agents. The study compares the incidence of nausea, vomiting, need for rescue medication, prolonged PACU time, and unplanned hospital admission in patients with…
- Trial name
- NCT00659737
- Testing
- Aprepitant, Scopolamine
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Drexel University College of Medicine
Urinary Retention, Urinary Tract Infections
Prevention of Post-operative Urinary Retention
The purpose of this study is to determine if tamsulosin ("FLOMAX") is effective in preventing post-operative urinary retention following abdominal surgery.
- Trial name
- POUR (NCT02486653)
- Testing
- Tamsulosin
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- University of Wisconsin, Madison
Pain, Postoperative
Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
The purpose of this study is to evaluate the patient experience when using gabapentin with other pain control medications after posterior spinal fusion surgery for scoliosis in adolescents.
- Trial name
- NCT01977937
- Testing
- Gabapentin 250mg/5mL NDC:59762-5025-01, Simple Syrup
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Oregon Health and Science University
Postoperative Pain, Carpal Tunnel Release
Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries
The purpose of this study is to determine the efficacy of intra-operative administration of IV tylenol and/or IV toradol in minimizing post-operative pain for carpal tunnel patients and distal radius fracture patients.
- Conditions
- Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
- Trial name
- NCT02313675
- Testing
- Acetaminophen, Ketorolac Tromethamine, Saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- John Fowler
Dehydration, Diverting Ileostomy, Loperamide
Use of Post Operative Loperamide in Colorectal Patients After Diverting Ileostomies
Dehydration post creation of a diverting ileostomy is a common and debilitating problem faced by patients undergoing ileal-anal pouch anastomoses for both inflammatory bowel disease and familial adenomatous polyposis (FAP)…
- Trial name
- NCT02263365
- Testing
- Loperamide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Cedars-Sinai Medical Center
Obesity &Amp; Overweight, General Anesthetic
Postoperative Opioid Consumption in Gastric Sleeve Surgery
The study aimed to compare balanced anesthesia protocols using only opioids as analgesics during induction in gastric sleeve surgery with protocols using opioids and ketamine together in terms of anesthesia management, opioid…
- Conditions
- Obesity &Amp; Overweight, General Anesthetic, Ketamine
- Trial name
- POCiGSS (NCT07135154)
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Balikesir University
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