Clinical trials: Post-Partum Hemorrhage
Postpartum Hemorrhage
Prophylactic Oxytocin Before Versus After Placental Delivery to Reduce Blood Loss in Vaginal Delivery
Randomized controlled study to assess the efficacy and safety of the timing of administration of prophylactic oxytocin via intramuscular route (before compared to after placental delivery) on blood loss in vaginal delivery.
- Trial name
- NCT03006380
- Testing
- oxytocin
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Third Stage of Labor
Homeopathic Remedy for the Third Stage of Delivery
The homeopathic remedy consisting of Arnica and Bellis perennis have been shown in a previous pilot study (n=33) to reduce blood loss during the third stage of delivery, when compared with placebo treatment.
- Trial name
- NCT01156194
- Testing
- Homeopathy 1, Homeopathy 2
- Where
- Israel
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Anemia
Well Being of Obstetric Patients on Minimal Blood Transfusions
Postpartum haemorrhage (PPH) is one of the top five causes of maternal mortality in developed and developing countries. The most important treatment of PPH is red blood cell (RBC) transfusion.
- Trial name
- WOMB (NCT00335023)
- Testing
- Red blood cell transfusion
- Where
- Netherlands
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sanquin Research & Blood Bank Divisions
Post Partum Hemorrhage, Blood Loss
Estimating Blood Loss Using TritonTM in Vaginal Deliveries: A Validation Trial
This study will be a prospective cohort study. Patients who meet criteria for inclusion in the study will be approached for participation at same day of admission.
- Conditions
- Post Partum Hemorrhage, Blood Loss, Vaginal Bleeding, Vaginal Delivery
- Trial name
- ELUSIVE (NCT04277962)
- Testing
- Triton L and D system for estimation of blood loss at time of vaginal delivery
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Hemorrhage
Double Blind Placebo Controlled Bellis Perenis and Arnica Montana as a Drug for PPH
To look at the antihemmorhagic effect of 2 homeopathic drugs in women post delivery Bellis Perenis and Arnica montana
- Trial name
- NCT00405626
- Testing
- Bellis Perenis ,Arnica montana
- Where
- Israel
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Post Partum Haemorrhage, Cesarean Section Surgery
Role of Intravenous Calcium to Decrease Blood Loss During Intrapartum Cesarean Section
To determine the effectiveness of prophylactic intravenous calcium chloride administered after cord clamping in reducing postpartum blood loss during intrapartum cesarean section.
- Trial name
- NCT07550413
- Testing
- Calcium Chloride
- Where
- Pakistan
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Pak Emirates Military Hospital
Postpartum Hemorrhage
Oxytocin Infusions and Blood Loss in Patients Undergoing Elective Cesarean Delivery.
Although prior dose-finding studies have investigated the optimal bolus dose of oxytocin to initiate adequate uterine tone, it is unclear what oxytocin infusion regimen is required to maintain adequate uterine tone after…
- Trial name
- NCT01932060
- Testing
- Oxytocin Infusion
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hemorrhage
RCT of Zhi Byed 11 (ZB11) Versus Misoprostol in Tibet
Previous research has confirmed that hemorrhage is among the most commonly encountered pregnancy complications in the Tibet Autonomous Region (TAR).
- Trial name
- NCT00147420
- Testing
- Zhi Byed 11
- Where
- 3 sites in China
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Postpartum Hemorrhage
Effectiveness, Safety and Feasibility of Auxiliary Nurse Midwives' (ANM) Use of Oxytocin in Uniject™ to Prevent Postpartum Hemorrhage in India
This cluster randomized community-based trial is designed to test the hypothesis that the intramuscular administration of 10 IU of oxytocin in Uniject™ during the third stage of labor by an Auxiliary Nurse Midwife (ANM) at births…
- Trial name
- NCT01108302
- Testing
- Oxytocin in Uniject
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Obesity, Maternal, Post Partum Hemorrhage
Efficacy of Carbetocin in Prevention of Postpartum Hemorrhage in Obese Versus Non Obese Women
Postpartum hemorrhage [PPH] can have serious consequences and is the leading cause of maternal mortality globally. Uterine contractility plays an important role in post-delivery uterine involution; impaired contractility can…
- Trial name
- NCT06217354
- Testing
- Carbetocin 100 Microgram/mL Solution for Injection
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postpartum Hemorrhage
Coagulation Factors and Postpartum Hemorrhage
Objective is to analyze a possible association of coagulation factors peripartal with the occurrence of postpartum hemorrhage.
- Trial name
- NCT02604602
- Testing
- blood exam
- Where
- Switzerland
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Postpartum Hemorrhage
The Effect of Placental Cord Drainage on Postpartum Blood Loss
To determine if placental cord drainage decreases the blood loss after spontaneous vaginal delivery
- Trial name
- NCT05610345
- Testing
- Placental Blood Drainage, Placenta Blood Not Drained
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Post Partum Hemorrhage
Oxytocin vs Carbetocin at Cesarean Delivery in Women With Morbid Obesity
Postpartum hemorrhage (PPH) is a major cause of maternal death worldwide. Oxytocin is the most commonly used uterotonic drug for the active management of third stage labor, to reduce the risk of PPH and help deliver the placenta.
- Trial name
- NCT04902729
- Testing
- Carbetocin, Oxytocin
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Postpartum Hemorrhage
Buccal Misoprostol During Cesarean Section for Preventing Postpartum Hemorrhage
Objective: to demonstrate that buccal misoprostol administration during cesarean delivery in women with risk factors for uterine atony decreases the need for additional uterotonic medications, uterine atony and postpartum…
- Trial name
- NCT01733329
- Testing
- Misoprostol, Folic Acid
- Where
- Mexico
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Postpartum Hemorrhage
Balanced Crystalloids in Postpartum Hemorrhage
Introduction: Obstetric hemorrhage is the most feared complication that can occur during childbirth and continues to be the leading cause of death in pregnant women worldwide, about 7 women die every hour in the world.
- Trial name
- NCT03824743
- Testing
- Lactate Ringer, Plasma-lyte
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fundación Santa Fe de Bogota
Postpartum Hemorrhage, Simulation Training
Hybrid Simulation in Postpartum Hemorrhage Training for Nursing Students
Abstract Postpartum hemorrhage (PPH) is a leading cause of maternal mortality and morbidity worldwide, requiring nursing students to acquire both theoretical knowledge and clinical competence for safe and effective management.
- Conditions
- Postpartum Hemorrhage, Simulation Training, Nursing Education, Clinical Readiness
- Trial name
- NCT07854106
- Testing
- Hybrid Simulation-Based PPH Training, Standard Education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Uludag University
Umbilical Cord
Timing of Umbilical Cord Clamping: One to Three Minutes vs. After Cessation of Cord Pulsation
The timing of umbilical cord clamping has been widely discussed in the scientific community. As part of the worldwide strategies to reduce childhood iron deficiency anemia, the incorporation of late clamping (at least one minute…
- Trial name
- CORD (NCT03844490)
- Testing
- CESSATION OF CORD PULSE, CONTROL
- Where
- Brazil
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Postpartum Hemorrhage
A Study of Self-administered Misoprostol to Prevent Bleeding After Childbirth in the Community (MamaMiso)
Postpartum hemorrhage (PPH) is a major cause of maternal death in the developing world. An important strategy in the prevention of deaths is the use of uterotonic drugs for PPH prophylaxis.
- Trial name
- NCT01510574
- Testing
- Misoprostol
- Where
- 4 sites in Uganda
- Volunteers
- 749 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Postpartum Hemorrhage
Active Versus Expectant Management of the Third Stage of Labor
The purpose of this study is to determine if giving oxytocin immediately after delivery causes less bleeding, transfusion needs and hastens delivery of placenta.
- Trial name
- NCT00473707
- Testing
- Active management of the third stage of labor, Expectant management of the third stage of labor, Oxytocin and gentle cord traction with fundal massage
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Third Stage of Delivery
Maternal Outcomes Following Manual Lysis of the Placenta.
Comparison of maternal outcomes following manual lysis of placenta 15 vs 30 minutes after delivery. A primary outcome of the drop in hemoglobin will be compared between the two groups.
- Trial name
- NCT03626844
- Testing
- Manual Lysis of Placenta after 15 minutes (Intervention), Manual Lysis of Placenta after 30 minutes (Control)
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Nazareth, Israel