Clinical trials: Post-Stroke Spasticity
Stroke, Spasticity, Muscle
Using Shear Wave Ultrasound Elastography for Follow up After Anti-spastic Intervention Among Stroke Patients
Spasticity of stroke patient, a very common complication in clinical practice, affects performance of hand function and gait pattern. It also interferes with quality of life of patients severely.
- Conditions
- Stroke, Spasticity, Muscle, Botulism, Ultrasound
- Trial name
- NCT04550793
- Testing
- Botulinum toxin injection
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Muscle Spasticity
CORETOX® in Treatment of Post Stroke Upper Limb Spasticity (Phase3)
The purpose of this study is to evaluate the efficacy and safety of CORETOX® in the treatment of post-stroke upper limb spasticity
- Trial name
- NCT03289702
- Testing
- CORETOX®, BOTOX®
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Medy-Tox
Upper Limb Spasticity After Stroke
A Prospective, Non-interventional Survey to Evaluate Injection Intervals and Treatment Modalities of Botulinum Toxin A (BoNT-A) in Adult Patients Suffering From Upper Limb Spasticity After Stroke
The purpose of the protocol is to evaluate injection intervals and treatment modalities up to 3 years follow-up of botulinum toxin A (BoNT-A) in adult patients suffering from upper limb spasticity after stroke.
- Trial name
- DECIDE (NCT01239628)
- Where
- 11 sites in Belgium
- Volunteers
- 45 people
- Sponsor
- Ipsen
Stroke
Morphological Characteristics of the Upper and Lower Extremities Using Ultrasound Examination After Stroke.
Introduction A large number of stroke patients develop spasticity in the upper and lower extremities, which is one of the clinical signs of damage to motor neuron 1, causing abnormal postures and movement patterns due to motor…
- Trial name
- Spasticity (NCT07156760)
- Testing
- Ultrasound diagnostics
- Where
- 2 sites in Chile
- Volunteers
- 80 people
- Sponsor
- Universidad de La Frontera
Stroke
Robot Aided Rehabilitation - Intervention
Sensorimotor impairments following stroke often involve complex pathological changes across multiple joints and multiple degrees of freedom of the arm and hand, thereby rendering them difficult to diagnose and treat.
- Trial name
- Aim2&3 (NCT02359253)
- Testing
- Passive stretching, Passive movement, IntelliArm
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Maryland, Baltimore
Stroke, Post-Stroke Spasticity
Effect of Extracorporeal Shock Wave Therapy on Spasticity and Mobility in Stroke Patients
This study aims to evaluate the effectiveness of extracorporeal shock wave therapy (ESWT) in individuals with lower limb spasticity following stroke.
- Conditions
- Stroke, Post-Stroke Spasticity, Lower Limb Spasticity
- Trial name
- ESWT-STROKE (NCT07523243)
- Testing
- Extracorporeal Shock Wave Therapy (ESWT)
- Volunteers
- 85 people
- Sponsor
- Istanbul Medipol University Hospital
Spastic Gait, Spastic
Exoskeleton Robotic Assisted Gait Training in Spastic Stroke Post Botulinum Toxin A Injection
The purpose of this project is to examine and compare the immediate and long-term effects of combined Botulinum toxin type A(BoNT-A) injection with exoskeleton Robotic assisted gait training (RABT) in patients with post-stroke…
- Trial name
- NCT06070987
- Testing
- BoNT-A injections, RF BoNT-A injection in first period and robot therapy, RF BoNT-A injection in second period and robot therapy
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke
Electrical Stimulation After Botulinum Toxin Injections to the Upper Extremity
The purpose of this study is to investigate the effectiveness of using electrical stimulation to improve upper extremity function in stroke survivors who receive botulinum toxin injections for spasticity.
- Trial name
- NCT04217187
- Testing
- Neuromuscular Electrical Stimulation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Texas Woman's University
Spasticity
ETREAT Study on Effectiveness of Botulinum Toxin Type A Injections to Treat Post-stroke Upper and/or Lower Limb Spasticity
The objective of this study is to evaluate the effectiveness of BoNT-A on functional improvement in patients with post-stroke upper and/or lower limb spasticity in the early stage of spasticity development, according to routine…
- Trial name
- ETREAT (NCT02275312)
- Where
- 17 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Ipsen
Upper Limb Spasticity
Study of Intramuscular Injections of ABBV-950 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Spasticity
Spasticity is often observed as muscle tightness and stiffness in the upper and/or lower limbs. Upper limb spasticity can interfere with joint movement and its severity can range from mild to severe.
- Trial name
- NCT05956509
- Testing
- ABBV-950, BOTOX
- Where
- 9 sites in United States
- Volunteers
- 1 people
- Sponsor
- AbbVie
Spasticity as Sequela of Stroke, Nerve Transfers
Nerve Transfers in Post-stroke Spasticity
Stroke is nowadays a leading cause of disability with devastating sequelae. Upper limb spasticity is one of them. Nevertheless, not all the muscles are equally affected, as some may turn spastic or paretic and other remain…
- Trial name
- NCT04437056
- Testing
- Cognitive nerve transfers to spastic upper extremity muscles in stroke patients
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Spasticity, Spasticity in Participants With Multiple Sclerosis
Nerve Root Block in Spasticity
In this work the investigators propose to briefly apply kilohertz frequency alternating current via PNS device placed next to the isolated nerve in 4 patients undergoing peripheral neurectomy, just before cutting the nerve.
- Conditions
- Spasticity, Spasticity in Participants With Multiple Sclerosis, Spasticity Post Stroke, Spasticity Related to Any Cause Except Cerebral Palsy
- Trial name
- NCT06868342
- Testing
- High-frequency nerve conduction block
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Walton Centre NHS Foundation Trust
Spastic Equinovarus Foot
Efficiency of Botulinum Toxin Injection for Spastic Equinovarus Foot in Post Stroke Hemiparetic Patients
Botulinum toxin is the main treatment for focal spasticity but the effects of botulinum toxin injections with respect to limitations of gait activities are still discussed.
- Trial name
- NCT03405948
- Testing
- Intra muscular injection of Botulinum toxin
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Post-Stroke Chronic Upper Limb Spasticity
Effectiveness and Safety of SMART [Spastic Muscle Palpation by Anatomic Landscape for BoNT-A (Botulinumtoxin-A) Injection to Reduce Muscle Tone] BoNT-A Therapy With Dysport® in Patients With Post-stroke Chronic Upper Limb Spasticity (ULS) in Real-life Setting.
The purpose of this study is to collect data for Dysport® SMART BoNT-A therapy usage in an office-based setting in post-stroke participants with chronic (> 6 months) focal Upper Limb Spasticity who have been under stable oral…
- Trial name
- SMART-NIS (NCT05224349)
- Where
- 31 sites in Germany
- Volunteers
- 121 people
- Sponsor
- Ipsen
Stroke, Hemiplegia, Spastic
Condensed and Distributed Robotic Therapy in Spastic Stroke Post Botulinum Toxin Injection
The purpose of this project is to examine and compare the immediate and long-term effects of combined Botulinum toxin type A (BoNT-A) injection between condensed and distributed robot-assisted training (RT) programs in patients…
- Trial name
- NCT03321097
- Testing
- condensed RT group, distributed RT group
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke, Spasticity as Sequela of Stroke
Different Treatment Methods Effect on Upper Extremity Spasticity and Decreased Functionality After Stroke
The aim of our study is to objectively and clearly determine the differences between the Spasticity and Decreased Functionality in the Upper Extremity Flexor Group Muscles After Stroke, the Vibration, mBZHT and Physiotherapy and…
- Conditions
- Stroke, Spasticity as Sequela of Stroke, Limitation, Mobility
- Trial name
- NCT05747950
- Testing
- Vibration, Modified Constraint-İnduced Movement Therapy, Conventional Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Zuhal Şevval Gökdere
Stroke
Acute Effects of Physiotherapy Interventions on Biceps Brachii Muscle Tissue Perfusion After Stroke
This study aimed to investigate the acute effects of proprioceptive neuromuscular facilitation (PNF), the Bobath concept, and virtual reality (VR)-based interventions on biceps brachii tissue perfusion in individuals with chronic…
- Trial name
- NCT07853859
- Testing
- Proprioceptive Neuromuscular Facilitation (PNF), Bobath Concept, Virtual Reality (VR)-Based Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Izmir Bakircay University
Stroke, Hemiplegia
Functional Outcome of Hemiplegic Upper Extremity in Patients With Subacute Stroke After Kinesiotaping and Rehabilitation
1. To explore the role of sonoelastography with shear wave velocity to assess poststroke spasticity of affected arm and forearm muscles in patients with stroke. 2.
- Trial name
- NCT04027985
- Testing
- Kinesiotaping, Hand rehabilitation program
- Where
- Taiwan
- Volunteers
- 41 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke, Muscle Spasticity
Early Use of Botulinum Toxin in Spasticity Post Stroke.
Patients who survive a stroke are often left with an arm that cannot be used. One reason for this is that the muscles affected by the stroke become overactive. This is known as spasticity.
- Conditions
- Stroke, Muscle Spasticity, Contracture
- Trial name
- EUBoSS (NCT01882556)
- Testing
- onabotulinumtoxinA
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Sandwell & West Birmingham Hospitals NHS Trust
Hemiplegia, Spastic
Inter-rater Reliability of the Australian Spasticity Assessment Scale (ASAS) in Post-stroke Spasticity
The reliability of the Australian Spasticity Assessment Scale (ASAS) has been reported to be not high enough in adult patients with acquired brain damage.
- Trial name
- NCT04613661
- Testing
- Australian Spasticity Assessment Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Izmir Katip Celebi University