Clinical trials: Post-Thyroidectomy Hypoparathyroidism
Hypoparathyroidism
Perioperative Parathormone Measurement and Sodium Bicarbonate Infusion Test After Total Thyroidectomy
In the study will be included patients that have undergone total thyroidectomy and do not display obvious clinical or laboratory hypoparathyroidism.
- Trial name
- NCT00793689
- Where
- Greece
- Volunteers
- 127 people
- Sponsor
- Aristotle University Of Thessaloniki
Thyroid Diseases
Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy
Hypoparathyroidism is the most common complication after a total thyroidectomy surgery. It becomes permanent after 6 months. Untreated permanent hypoparathyroidism is a source of numerous complications in general and therefore…
- Trial name
- HYPOCAAVI (NCT04785443)
- Testing
- ICG, Control group
- Where
- France
- Volunteers
- 242 people
- Sponsor
- University Hospital, Brest
Hypoparathyroidism Postprocedural
Study on the Effects of Hypoparathyroidism on Post-thyroidectomy Health-related Quality of Life (QoL-hPTP)
Our study will evaluate the health related quality of life (HRQoL) after a thyroidectomy and the relevance of postoperative hypoparathyroidism.
- Trial name
- QoL-hPTP (NCT04604808)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Goiter
Outcomes of Different Thyroid Resections for Multinodular Non-toxic Goiter
The aim of this three-arm randomized study was to evaluate results of different thyroid resection modes among patients with bilateral multinodular non-toxic goiter, with special emphasis put on recurrence rate and morbidity rate…
- Trial name
- NCT00946894
- Testing
- Total thyroidectomy, Dunhill operation, Bilateral subtotal thyroidectomy
- Where
- Poland
- Volunteers
- 600 people
- Sponsor
- Jagiellonian University
Hypoparathyroidism
Predicting Risk Factors of Postoperative Hypocalcemia After Total Thyroidectomy
With increasing economic pressures to shorten the length of hospital stay, there has been much recent interest in studying risk factors for the development of postoperative hypocalcemia.
- Trial name
- NCT04372225
- Testing
- analysis of hypocalcemia
- Where
- France
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- Aix Marseille Université
Iatrogenic Hypocalcemia, Iatrogenic Hypoparathyroidism
Post-thyroidectomy Vocal Cord Paralysis Along With Hypocalcemia: STROBE - Guided Prospective Cohort
In the present study, the severity of recurrent laryngeal nerve injury (RLNI) and hypocalcemia (H) will be followed-up and the probable interrelation between them will be proposed considering the clinical situation of patients…
- Conditions
- Iatrogenic Hypocalcemia, Iatrogenic Hypoparathyroidism, Vocal Cord Paralysis, Vocal Cord Paresis
- Trial name
- NCT04396912
- Testing
- Total thyroidectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Umraniye Education and Research Hospital
Hypoparathyroidism Post-surgical, Quality of Life
Effects of Total Thyroid Removal on Parathyroid Function and Quality of Life
Postoperative hypoparathyroidism (hypoPT) is the most frequent complication after total thyroidectomy (TT). It is caused by impaired parathyroid function, leading to low calcium levels, patient discomfort, reduced quality of life…
- Trial name
- NCT07381998
- Testing
- high-dose calcium (400 mg x 4), vitamin D (19 mikg x 4), and active vitamin D supplementation (2 mikg x 2), Ommit routine blood test post operative day 1
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Aarhus University Hospital
Hypoparathyroidism Postprocedural, Hypocalcemia
Near Infrared (NIR) Autofluorescence Image-guided Thyroid Surgery
The objective of this ongoing randomized controlled trial is to examine whether the use of intra-operative NIR(near infrared) camera can reduce the number of patients who experience transient or persistent hypoparathyroidism…
- Conditions
- Hypoparathyroidism Postprocedural, Hypocalcemia, Surgery--Complications
- Trial name
- NCT04193332
- Testing
- NIR optical imaging camera
- Where
- 2 sites in Denmark
- Volunteers
- 214 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hypoparathyroidism, Quality of Life
Quality of Life Evaluation (SF-36) in Patients With Permanent Hypoparathyroidism After Total Thyroidectomy (Qol-Hypopara)
Persistent hypoparathyroidism is an underestimate but major complication of total thyroidectomy. The hypothesis of the investigators is that the mental health is impaired in hypoparathyroid patients compared with thyroidectomized…
- Trial name
- NCT04053647
- Testing
- Non-interventional study
- Where
- 6 sites in France
- Volunteers
- 143 people
- Sponsor
- Nantes University Hospital
Post-Thyroidectomy Hypoparathyroidism
Effectiveness Of Cervical Rehabilitation Program After Thyroidectomy
The aim of this research is to determine the Effects of cervical rehabilitation program on neck pain, ROM and disability after thyroidectomy. Randomized controlled trials will be done at Pakistan ordinance factory (POF) Hospital.
- Trial name
- NCT06020820
- Testing
- Cervical Rehabilitation program (Intervention Group) Group A, control group group B
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Hypocalcemia, Hypoparathyroidism
Vitamin D Levels and Postoperative Hypocalcemia After Total Thyroidectomy
Hypocalcemia is one of the most frequent complications of total thyroidectomy, a procedure used for benign as well as malignant conditions of the thyroid gland. Postoperative hypocalcemia is usually caused by hypoparathyroidism.
- Conditions
- Hypocalcemia, Hypoparathyroidism, Vitamin D Deficiency, Thyroidectomy
- Trial name
- NCT01039714
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- Aristotle University Of Thessaloniki
Hypoparathyroidism
Postoperative Dose of Parathyroid Hormone as a Marker for the Occurrence of Hypoparathyroidism After Total Thyroidectomy
The main objective of this study is to establish an optimal threshold Early parathormon (PTH) assay in order to exclude hypoparathyroidism , that is to say to obtain a negative predictive value of hypoparathyroidism highest…
- Trial name
- NCT02924532
- Testing
- immediate post operative bioassay of Parathyroid Hormone
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Permanent Hypoparathyroidism
Quality in Patients With Permanent Hypoparathyroidism After Total Thyroidectomy
Quality of life study. The study with include all patients operated with total thyroidectomy between 2005-2015 in Uppsala-Örebro healthcare region, Sweden.
- Trial name
- NCT04998968
- Where
- Sweden
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Endocrine Procedural Complications, Thyroid
Intraoperative Monitoring to Predict Postoperative Complications After Thyroidectomy
The goal of this study is to evaluate the role of intraoperative continous and intermittent neuromonitoring and intraoperative parathormone (PTH) to predict postoperative nerve morbidity and hypocalcemia.
- Conditions
- Endocrine Procedural Complications, Thyroid, Parathyroid; Deficiency, Laryngeal Injury
- Trial name
- PARACAL (NCT03309384)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Central Hospital, Nancy, France
Post-Thyroidectomy Hypoparathyroidism
Psychological Problems in Post Thyroidectomy Patients
Quality of life (QoL) refers to perceived well-being, and encompasses the evaluation of physical health, and physical, social, and psychological functioning .
- Trial name
- NCT06929104
- Testing
- No intervention
- Volunteers
- 127 people
- Sponsor
- Assiut University
Hypocalcemia, Hypoparathyroidism
NIRAF-Guided Parathyroid Identification During Thyroidectomy
This is a single-site, two-component prospective study evaluating whether near-infrared autofluorescence (NIRAF) imaging can improve intraoperative identification of parathyroid glands during thyroidectomy and reduce…
- Conditions
- Hypocalcemia, Hypoparathyroidism, Thyroid Diseases, Goiter, Nodular
- Trial name
- NCT07617584
- Testing
- Wearable Near-Infrared Autofluorescence Imaging System
- Where
- North Macedonia
- Volunteers
- 280 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Hypoparathyroidism Postprocedural
Improving Safety in Pediatric Thyroidectomy by PTH Measurements
We implemented a previously reported algorithm based on intra-postoperative PTH measurements with selected cut-off values, both to predict post-thyroidectomy hypoparathyroid hypocalcemia, and to guide postsurgical management.
- Trial name
- NCT04690842
- Testing
- PTH measurements post-thyroidectomy (at 5 and 60 min post thyroid removal)
- Volunteers
- 66 people
- Sponsor
- Hospital de Niños R. Gutierrez de Buenos Aires
Thyroid Disease, Hypoparathyroidism Postprocedural
Autofluorescence and Indocyanine Green to Avoid Hypocalcemia After Thyroidectomy
Hypoparathyroidism (and the resulting hypocalcemia) remains the most common morbidity after a total thyroidectomy. The identification and preservation of parathyroid glands during neck surgery has always been challenging but is…
- Trial name
- NCT05117853
- Testing
- Autofluorescent detection + Injection of indocyanine green, Gold standard of visual identification and evaluation of viability of the parathyroid glands.
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Onze Lieve Vrouw Hospital
Hypocalcemia, Total Thyroidectomy
Determination of Parathyroid Function by Fluorescence With Indocyanine Green (ICG) After Total Thyroidectomy
The intensity of parathyroid fluorescence that occurs after intravenous injection of indocyanine green during the performance of a total thyroidectomy correlates with postoperative parathyroid function and could be used as a…
- Conditions
- Hypocalcemia, Total Thyroidectomy, Hypoparathyroidism Postprocedural
- Trial name
- NCT04012476
- Testing
- Indocyanine Green
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Son Espases
Hypoparathyroidism Postprocedural, Quality of Life
Quality of Life Related to Different Treatment Protocols for Post-thyroidectomy Hypoparathyroidism
This study aims to compare two different protocols commonly used in the management of post thyroidectomy hypoparathyroidism : PTH based calcium repletion and empiric repletion.
- Trial name
- NCT03249012
- Testing
- Empiric use of Calcium Carbonate and Calcitriol, PTH based Calcium Carbonate and Calcitriol repletion
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- CHU de Quebec-Universite Laval