Clinical trials: Post-Traumatic
Intrusive Memories, PTSD
The Effect of Oxytocin on the Consolidation of Trauma-Associated Memories
The purpose of the study is to examine whether oxytocin and certain polygenic risk scores affect the development of intrusive memories, a cardinal symptom of PTSD.
- Trial name
- NCT03875391
- Testing
- Oxytocin
- Where
- Germany
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Traumatic Brain Injury, Post-concussive Symptoms
MEG and DTI of Neural Function and Connectivity in Traumatic Brain Injury
The overall hypothesis is that the long-term cognitive and behavioral sequelae of traumatic brain injury (TBI) are due to selective disruption of the long association white matter tracts of the cerebral hemispheres, with…
- Trial name
- Dana-REAC (NCT01298557)
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Gut Microbiota, Spleen Injury
Microbiota is Related With Increasing Infection Rates After Splenectomy
Studies has shown an increasingly infection rate after splenectomy, and there is a potential correlation between microbiota and immune system.
- Conditions
- Gut Microbiota, Spleen Injury, Infection
- Trial name
- NCT03420599
- Testing
- splenectomy
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Post-Traumatic Stress Disorder, Depression
Long Term Health Outcomes of Women Veterans' Service During the Vietnam Era
Little is known about the long-term health and mental health status of women Vietnam veterans. For many of these women, the effects of this war are still present in their daily lives.
- Conditions
- Post-Traumatic Stress Disorder, Depression, Diabetes, Cardiovascular Disease
- Trial name
- Health ViEWS (NCT00958061)
- Where
- United States
- Volunteers
- 4,219 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Ankle Fractures, Post-traumatic Osteoarthritis
Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress
The proposed study evaluates the effect of carbon fiber brace design on forces across the ankle joint. Research suggests that ankle arthritis develops after ankle fracture, in part, due to elevated forces on the cartilage.
- Conditions
- Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
- Trial name
- PRMRP-FPA2 (NCT04562896)
- Testing
- Custom Carbon Fiber Dynamic Orthosis (CDO)
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Iowa
TBI (Traumatic Brain Injury), Brain Concussion
Dual-Task Exercise for Mild Traumatic Brain Injury (mTBI)
The investigators previously developed a virtual 14-day dual-task walking exercise program and tested its feasibility with individuals with mild traumatic brain injury (mTBI) history.
- Conditions
- TBI (Traumatic Brain Injury), Brain Concussion, Clinical Trial, Rehabilitation
- Trial name
- NCT06037603
- Testing
- Brain & Walk Exercise Every Day (BraW-Day)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Traumatic Brain Injury, Concussion
Enhancing Cognitive and Neurobehavioral Functions After Repetitive Traumatic Brain Injuries (rTBI) in Retired NFL Players and Military Veterans.
The purpose of this study is to compare different combinations of cognitive training in retired professional football players and military veterans with a history of repeated concussions and persistent symptoms of impaired…
- Conditions
- Traumatic Brain Injury, Concussion, Mild Cognitive Disorder
- Trial name
- NCT02699476
- Testing
- Psycho-Social Therapy, Cognitive Behavioral Computer Training, Interactive Trainer-Subject Sessions
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brain & Body Health Foundation
Posttraumatic Stress Disorder, Post-Traumatic Stress Disorder
Geodon (Ziprasidone) for Posttraumatic Stress Disorder
Atypical antipsychotics have shown promise in the treatment of depression and anxiety, which are prominent symptoms of PTSD. The profile of the atypical antipsychotic, ziprasidone (Geodon), suggests possible anxiolytic and…
- Conditions
- Posttraumatic Stress Disorder, Post-Traumatic Stress Disorder, PTSD
- Trial name
- NCT00208208
- Testing
- Ziprasidone
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Creighton University
PTSD, Intrusive Memories
Estradiol and Intrusive Memories
The aim of the current project is to investigate the impact of 3mg of oral estradiol valerate on the formation of intrusive memories after analog trauma.
- Conditions
- PTSD, Intrusive Memories, Intrusion Symptom, Trauma
- Trial name
- EstraMemo (NCT07419594)
- Testing
- Estradiol Valerate
- Where
- Germany
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Prolonged Post-traumatic Stress Disorder
Meditation for Emotional Numbing in Post-Traumatic Stress Disorder
For individuals suffering from posttraumatic stress disorder (PTSD), the emotional numbing and isolation that are a core aspect of their suffering and consistently impedes remediation often remains after first-line treatments are…
- Trial name
- NCT02163941
- Testing
- Compassion Training
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Emory University
Traumatic Brain Injury, Cerebral Palsy
Walking Dynamic Among Children With Brain Damge
The goal of the present study was to look at the effect of changing walking parameters on the dynamic walking characteristics among children post severe traumatic brain injury, children with cerebral palsy and typically developed…
- Trial name
- NCT02839369
- Testing
- walking under varies conditions
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Alyn Pediatric & Adolescent Rehabilitation Hospital
Severe Traumatic Brain Injury, Trauma
Impact of Severe Brain Injury on Neuro-vascular and Endothelial Regulation of Peripheral Microcirculation.
Severe brain injury (SBI) is one of the world's leading causes of death and disability in young adults, but its peripheral vascular consequences in humans are poorly understood.
- Trial name
- MicroTC (NCT04597879)
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
PTSD
Clinical Assessment of the Flash - Eye Movement Desensitization and Reprocessing
To assess the Flash version of EMDR in reductions of the disturbance of upsetting memories at post-intervention, and 1-month follow up within a double-blinded, online 2-arm randomized controlled trial (RCT) with self-report…
- Trial name
- Flash-EMDR (NCT05262127)
- Testing
- Flash Version of EMDR
- Where
- 2 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- York University