Clinical trials: Post-Traumatic Stress Disorder
Post Traumatic Stress Disorder
Using Adhesive Biosensor Patches to Characterize the Biochemical Phenotype in PTSD
A psychiatric diagnosis of post-traumatic stress disorder (PTSD) is currently based mainly on non-quantitative elements, such as interviews and subjective impressions.
- Trial name
- NCT04071132
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nadav Goldental
PTSD, Addiction
The Course and Outcome of Integreated Trauma and Addiction Treatment Between PTSD and CPTSD
In the ICD-11 post-traumatic stress disorder (PTSD) and complex PTSD (CPTSD) are distinguished. CPTSD is associated with early childhood traumatization and more severe symptom patterns.
- Trial name
- NCT06588309
- Testing
- Eye movement desensitization and reprocessing (EMDR), CRA
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IrisZorg
Borderline Personality Disorder, Depressive Disorder
Systematic Use of Telepsychiatry for Outpatients
Implementation and evaluation of video consultation in psychiatric outpatient treatment. The study will focus on patients' experiences regarding the use of VC.
- Conditions
- Borderline Personality Disorder, Depressive Disorder, Ptsd, Anxiety Disorders
- Trial name
- NCT05516238
- Testing
- Case management
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Post Traumatic Stress Disorder, Depression
Randomized Control Trial on Trauma Focused CBT in Zambia
The purpose of this study is to study the effectiveness of Trauma Focused Cognitive Behavioral Therapy in subset of children who are affected by trauma with significant mental health symptomatology in order to 1) examine the…
- Conditions
- Post Traumatic Stress Disorder, Depression, Risk Behaviors
- Trial name
- NCT01624298
- Testing
- Trauma Focused Cognitive Behavioral Therapy
- Where
- Zambia
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Intrusive Thought, Psychological Trauma
Towards a Post-exposition Pharmacological Prophylaxis for Post-traumatic Stress Disorder
In this study, we investigate the role that deep sleep plays in the prevention of posttraumatic stress disorder after someone has been exposed to a trauma by boosting deep sleep with two drug conditions compared to placebo…
- Conditions
- Intrusive Thought, Psychological Trauma, Inflammatory Response, Physiological Stress
- Trial name
- TRAUMA-PRO (NCT04508166)
- Testing
- Dexmedetomidine, Gamma-Hydroxybutyrate, Experimental Model Trauma Film
- Where
- Switzerland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Psychiatric University Hospital, Zurich
PTSD - Post Traumatic Stress Disorder, Depression/Anxiety
An Integrative, Digital Health Approach to Veteran-Centered PTSD Care
The goal of this study is to test the effectiveness of a stress self-management mobile health system (smartphone app + wearable sensor) alongside an intense physical cycling intervention to reduce symptoms of stress in a veteran…
- Trial name
- NCT06993012
- Testing
- Mobile Health Stress Self Management System, Intensive Cycling Activity
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Health Behavior
Wearable Emotion Prosthetics for Post Traumatic Stress Disorder
Involuntary stress reactions including hyper-reactivity and dissociation are key diagnostic features of many psychiatric disorders, are difficult to treat, and predict poor outcomes in conventional and neurobehavioral…
- Trial name
- EP-PTSD (NCT03529981)
- Testing
- Tuned Vibroacoustic Stimulation (TVS), no active intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Substance Use Disorders, Post Traumatic Stress Disorder
M-Health for Teen Substance Abuse and Mental Illness Pilot
The study is exploring the ease and ability to integrate a mobile application in outpatient behavioral health treatment. There are two major aims to the study: 1) Determine feasibility and acceptability of integrating a mobile…
- Conditions
- Substance Use Disorders, Post Traumatic Stress Disorder, Adolescent Behavior, Mental Health Disorder
- Trial name
- NCT04281719
- Testing
- Mobile Application (working name: Bright Path)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Post-traumatic Stress Disorder, Cocaine Use Disorder
Reconsolidation Blockade of Intrusive Trauma- and Cocaine-related Memories
An investigation of the effect of matrix-metalloproteinase-(MMP)-9 inhibition with minocycline on the reconsolidation of trauma- or cocaine-related memories
- Trial name
- Memocycline (NCT05902819)
- Testing
- Imagery, Minocycline
- Where
- Switzerland
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Psychiatric University Hospital, Zurich
Preterm Delivery
Factors Associated With Post-Traumatic Stress Disorder in Patients With After Preterm Delivery
Each year in France, between 50,000 and 60,000 children are born prematurely (< 37 weeks of amenorrhea). Literature has shown that preterm deliveries can be associated with the development of PTSD (Post-Traumatic Stress Disorder)…
- Trial name
- PTSD-preterm (NCT03344471)
- Testing
- Passation of questionnaires
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
PTSD, Critical Illness
The Experiences of Children and Caregivers Given PICU Storybooks
1. To assess the acceptability and feasibility of a study design aimed at evaluating the efficacy of a newly developed intervention for children and their caregivers following discharge from PICU 2.
- Conditions
- PTSD, Critical Illness, Depression, Anxiety
- Trial name
- NCT04041401
- Testing
- PICU storybook
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Posttraumatic Stress Disorder, Cardiovascular Diseases
NightWare and Cardiovascular Health in Adults With PTSD
The purpose of this study is to determine whether NightWare therapeutic intervention improves biomarkers of vascular aging and autonomic function in adults with nightmares related to PTSD.
- Conditions
- Posttraumatic Stress Disorder, Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness
- Trial name
- NCT05365607
- Testing
- NightWare
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Post Traumatic Stress Disorder, Insomnia Disorder
RESILIENT : A Self-Managed Online Platform for Victims of Sexual Assault
There are 636,000 self-reported cases of sexual assault annually in Canada, and nine out of ten persons who have experienced sexual assault are women.
- Conditions
- Post Traumatic Stress Disorder, Insomnia Disorder, Major Depressive Disorder
- Trial name
- NCT05811897
- Testing
- Self-Managed Online Treatment, Therapist-Assisted Online Treatment
- Where
- Canada
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Laval University
Posttraumatic Stress Disorder, Depression
Randomized Controlled Trial of the Effectiveness of Group Treatment With War-Exposed Bosnian Adolescents
Context: This is the first multi-site randomized controlled study of the effectiveness of a group treatment for war-exposed adolescents delivered in-country within a public school system.
- Conditions
- Posttraumatic Stress Disorder, Depression, Grief (Traumatic Grief and Existential Grief)
- Trial name
- NCT00480480
- Testing
- Trauma and Grief Component Therapy for Adolescents (Group Version)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Brigham Young University
Post-Traumatic Stress Disorder
Risperidone in the Treatment of PTSD in Women Survivors of Domestic Abuse and Rape Trauma
This medical study is an assessment of clinical response in women with Posttraumatic Stress Disorder (PTSD) due to domestic violence or rape trauma when treated with risperidone.
- Trial name
- NCT00208182
- Testing
- Risperidone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Creighton University
Depressive Disorder, Anxiety Disorders
AI to Support Mental Health Case Management Providers
The goal of this clinical trial is to assess the effectiveness of an artificial intelligence (AI) platform for case managers in a nonprofit health system specializing in mental health and substance use disorder.
- Conditions
- Depressive Disorder, Anxiety Disorders, Substance Use Disorders, Post Traumatic Stress Disorder
- Trial name
- NCT06280170
- Testing
- Artificial Intelligence platform for case managers
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Eleos Health
Psychological Trauma, Posttraumatic Stress Disorder PTSD
Psychometric and Patholinguistic Assessment of Psychotrauma Related to Natural Hazards in the Commune of "Le Prêcheur"
The project is to study the evolution of mental health in a little town of the French Martinique (Le Prêcheur) by using an innovative method of analysis that combines patholinguistic and psychometric indications for patients who…
- Conditions
- Psychological Trauma, Posttraumatic Stress Disorder PTSD, Mass Casualty Incidents
- Trial name
- EP3LAN (NCT04479670)
- Where
- Martinique
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Stress Disorders, Post-Traumatic
Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV
The purpose of this study is to find out why patients with post-traumatic stress disorder (PTSD) have an increased risk for heart disease and high blood pressure later in life.
- Trial name
- ANG-P (NCT02560805)
- Testing
- Microneurography, Combat virtual reality video clip, Handgrip Exercise
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Emory University
Posttraumatic Stress Disorder, Major Depressive Disorder
Behavioral Activation + Cognitive Processing Therapy for PTSD and Comorbid MDD
This study is a randomized controlled trial comparing an integrated treatment, Behavioral Activation + Cognitive Processing Therapy (BA + CPT), to CPT alone among active-duty service members with posttraumatic stress disorder…
- Trial name
- NCT02874131
- Testing
- Behavioral Activation, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Post Traumatic Stress Disorder
Observational Study of the Evaluation of Post Traumatic Stress Post Stroke
This prospective, observational, multicentre study evaluates the existence of Post-traumatic stress disorder following a stroke at 3 and 6 months after the management of the patient.
- Trial name
- SPTD (NCT04299841)
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- CHI MONT DE MARSAN ET PAYS DES SOURCES