Clinical trials: Post-Traumatic Stress Disorders
Covid-19
Recovery After Critical Covid-19 Infection
The study focuses on the recovery of respiratory, cardiovascular and neurological/neuropsychological recovery after intensive care treatment for covid-19.
- Trial name
- RECOVID (NCT04864938)
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Depression, Panic Disorder
Evaluating the Effects of Stress in Pregnancy
This study will evaluate pregnant women with a past or current diagnosis of depression or anxiety to gain a better understanding of how these disorders can affect an infant's development, both during and after pregnancy.
- Conditions
- Depression, Panic Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder
- Trial name
- NCT00525226
- Where
- United States
- Volunteers
- 1,431 people, healthy volunteers welcome
- Sponsor
- Emory University
Post Traumatic Stress Disorder, Technology
Improving Quality of Care in Child Mental Health Service Settings
The investigators recently completed an NIMH R34 in which they piloted a patient- and provider-informed tablet-based toolkit designed to facilitate delivery of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) - a treatment…
- Conditions
- Post Traumatic Stress Disorder, Technology, Child Abuse
- Trial name
- NCT03305458
- Testing
- TFCBT, eTFCBT
- Where
- United States
- Volunteers
- 713 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Post-traumatic Stress Disorders
Tetris to Reduce Intrusive Memories in Parents After PICU
The purpose of this study is to examine the acceptability and feasibility of a brief behavioural intervention involving Tetris gameplay to prevent intrusive traumatic memories in parents after paediatric intensive care.
- Trial name
- NCT04186962
- Testing
- Behavioral: Simple cognitive task
- Where
- 2 sites in United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- King's College London
Posttraumatic Stress Disorder
Intensive 7-day Treatment for PTSD Combining Ketamine With Exposure Therapy
The purpose of this study is to combine a single infusion of Ketamine with 7-days of trauma focus psychotherapy to relieve post traumatic stress disorder (PTSD) symptoms more effectively.
- Trial name
- PTSD (NCT02727998)
- Testing
- Ketamine, Midazolam
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yale University
Tinnitus, Traumatic Brain Injury
Investigating the Neurobiology of Tinnitus
The investigators hypothesize that individual differences exist in resting-state cortical attention, control, sensory, and emotion networks prior to noise exposure and these differences predispose some to the development of…
- Conditions
- Tinnitus, Traumatic Brain Injury, Post Traumatic Stress Disorder
- Trial name
- NCT01294124
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Posttraumatic Stress Disorder (PTSD)
fMRI Predictors of Treatment Response in Posttraumatic Stress Disorder (PTSD)
To employ a fear learning-extinction paradigm with functional magnetic resonance imaging (fMRI) and skin conductance response (SCR) assessments among patients with posttraumatic stress disorder (PTSD) and trauma exposed healthy…
- Trial name
- NCT01576510
- Testing
- Prolonged Exposure (PE)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Stress Disorders, Post-Traumatic, Stress Related Disorder
Mindfulness-SOS: Stress Reduction for Refugees
The COVID-19 pandemic crisis is associated with a wide range of stressors for the general population. For forcibly displaced persons (FDPs), the turmoil of this crisis is magnified significantly, and elevated pre-existing…
- Trial name
- NCT04761510
- Testing
- Mindfulness-SOS for Refugees
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Haifa
PostTraumatic Stress Disorder
Equine Assisted Psychotherapy for PTSD
The purpose of this study is to assess the efficacy of Equine Assisted Psychotherapy on PTSD symptoms in veterans with PTSD as compared with existing care.
- Trial name
- NCT03039361
- Testing
- Equine Assisted Psychotherapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Alcohol Use Disorder, PTSD
Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder
The project will examine whether a computerized neuroscience-based cognitive training program can improve cognitive functioning and recovery outcomes among Veterans with Alcohol Use Disorder and co-occurring PTSD.
- Conditions
- Alcohol Use Disorder, PTSD, Cognitive Dysfunction
- Trial name
- NCT02929979
- Testing
- Cognitive Training
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PTSD, Alzheimer Disease
First-In-Human (FIH), Single Ascending Dose (SAD) Study of FluoroEthylNorMemantine (FENM)
The goal of this First-In-Human (FIH) trial is to learn about safety and PharmacoKinetics (PK) in healthy adult volunteers. The main questions it aims to answer are: What is the safety of single ascending doses of the…
- Conditions
- PTSD, Alzheimer Disease, Brain Diseases, Neuro-Degenerative Disease
- Trial name
- NCT05921929
- Testing
- Fluoroethylnormemantine (FENM)
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- ReST Therapeutics
Psychological, Burnout
Psychological Support for Intensive Care Nurses During the COVID-19 Pandemic: The PROACTIVE Feasibility Trial
The psychological health of frontline healthcare workers, caring for critically ill patients with COVID-19, has deteriorated during the pandemic. Nurses appear to be most seriously affected.
- Conditions
- Psychological, Burnout, Post Traumatic Stress Disorder, Anxiety
- Trial name
- NCT05087186
- Testing
- Guided imagery and FLASH technique
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Stress Disorders, Post-Traumatic
fMRI to Examine the Effect of CBTm to Increase Resiliency for PTSD
A substantial proportion of public safety personnel (PSP) develop service-related posttraumatic stress disorder (PTSD). PTSD is associated with a range of negative outcomes and its exact underlying neurophysiological mechanism is…
- Trial name
- NCT03998501
- Testing
- Cognitive Behavioral Therapy with Mindfulness Class
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
PTSD
Complementary and Alternative Interventions for Veterans With Posttraumatic Stress Disorder
The overarching aim of this proposal is to research whether meditation-based treatments are effective in decreasing posttraumatic stress disorder (PSTD) symptoms in veterans, which complementary and alternative (CA) treatments…
- Trial name
- NCT01512303
- Testing
- Sudarshan Kriya Yoga, Mindfulness-Based Stress Reduction
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
PTSD
Delivery Considerations of Cognitive Processing Therapy for PTSD
Review treatment outcomes of modifications to standard delivery of CPT for PTSD that are delivered as routine care at in VA outpatient clinic.
- Trial name
- NCT04765319
- Testing
- CPT for PTSD
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- VA Salt Lake City Health Care System
Mental Health Wellness 1, PTSD
Mental Health Outcomes in Healthcare Workers During COVID-19
An online survey will be sent to healthcare workers (HCWs) in acute care hospitals to explore a variety of risk factors for negative psychological outcomes and levels of anxiety, depression and post-traumatic stress symptoms…
- Conditions
- Mental Health Wellness 1, PTSD, Anxiety, Stress
- Trial name
- NCT04397848
- Where
- Canada
- Volunteers
- 3,852 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
PTSD, Ketosis
Ketone Supplementation in Individuals With PTSD
The purpose of this study is to determine if a 6-week period of ketone salt supplementation affects physiological, emotional, cognitive, and/or behavioral health markers in individuals with PTSD.
- Trial name
- NCT04083352
- Testing
- Pruvit Ketomax Ketone Salt
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Augusta University
Burnout, Self-compassion
Better Together: an Online Physician Coaching Program for Medical Trainees
This is a single-institution randomized controlled trial. 101 female residents were recurited from the University of Colorado School of Medicine.
- Conditions
- Burnout, Self-compassion, Moral Injury, Impostor Phenomenon
- Trial name
- NCT05280964
- Testing
- Better Together Physician Coaching
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Post-Traumatic Stress Symptoms, Poor Sleep Quality
Psychoeducation-Supported Breathing and Relaxation for Earthquake Survivors
This randomized controlled study evaluated whether a structured program combining psychoeducation, breathing exercises, and relaxation techniques could reduce post-traumatic stress symptoms and improve sleep quality among adult…
- Trial name
- NCT07781904
- Testing
- Psychoeducation-Supported Breathing and Relaxation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Rana Ceviz
PTSD, Trauma
PPG Project 3 - PET/MRI of the Brain-hematopoiesis-atherosclerosis Axis in PTSD Patients
Project 3 of the PPG grant "Stress and Atherosclerotic Plaque Macrophages A Systems Biology Approach," funded by the NHLBI, examines the relationship between psychosocial stress and atherosclerotic inflammation, cell…
- Conditions
- PTSD, Trauma, Healthy
- Trial name
- NCT03279393
- Testing
- fluorodeoxyglucose (FDG)-PET/MRI
- Where
- 2 sites in United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Zahi Fayad