Clinical trials: Post-Traumatic Stress Disorders
PTSD - Post Traumatic Stress Disorder
Rapid Recovery: Gut Microbiome Correction for PTSD
This cohort clinical trial (RAPID RECOVERY) investigates the role of gut microbiome in mental health and the effectiveness of personalized microbiome correction in individuals with post-traumatic stress disorder (PTSD).
- Trial name
- RAPID RECOVERY (NCT07623967)
- Testing
- Investigational Probiotic Preparation
- Where
- Ukraine
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Uzhhorod National University
Posttraumatic Stress Disorder
Norepinephrine Transporter Availability in PTSD
The objective of this proposal is to collect pilot data to characterize the binding of [11C]MENET in combat-exposed war veterans with posttraumatic stress disorder (PTSD).
- Trial name
- NCT01799837
- Testing
- [C-11]MENET
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Emory University
Posttraumatic Stress Disorder
Emotional Memory Reactivation in Posttraumatic Stress Disorder
Converging lines of evidence have implicated the amygdala in the pathophysiology of posttraumatic stress disorder. The primary purpose of our study is to assess the effect of propanolol, a beta adrenergic antagonism, on amygdala…
- Trial name
- VIVITRAU (NCT01239173)
- Testing
- AVLOCARDYL
- Where
- France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Posttraumatic Stress Disorder
Results From a 24 Week Trial of EMDR Combined With Venlafaxine XR
Approximately 150 active duty service members meeting Diagnostic and Statistical Manual version 5 (DSM-5) criteria for posttraumatic stress disorder (PTSD) and scoring 50 or above on the Clinician Administered PTSD Score for…
- Trial name
- EMDRVEN (NCT02433353)
- Testing
- Venlafaxine XR, EMDR
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bayne-Jones Army Community Hospital
PTSD
Post-Deployment Afghanistan/Iraq Trauma Related Inventory of Traits (PATRIOT): Phase 1 (Feasibility Study)
The long-term goal of this research project is to identify genes that contribute to or guard against developing posttraumatic stress disorder (PTSD) and to better understand how genes and life experiences work together to impact…
- Trial name
- PATRIOT (NCT01153529)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Trauma and Stressor Related Disorders
The Effect of Cognitive Behavioral Therapy on Post-Traumatic Stress Symptoms in Nursing Students
Objectives: This research was planned to examine the effect of cognitive behavioral therapy on the post-traumatic stress symptoms of nursing students during the COVID-19 pandemic.
- Trial name
- NCT06037005
- Testing
- Cognitive Behavioral Therapy Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Substance Use Disorders, Drug Abuse
Leveraging Implementation Science to Increase Access to Trauma Treatment for Incarcerated Drug Users
The unmet need for effective addiction treatment within the criminal justice system "represents a significant opportunity to intervene with a high-risk population" according to NIDA's 2016-2020 strategic plan.
- Conditions
- Substance Use Disorders, Drug Abuse, Alcohol Abuse, Posttraumatic Stress Disorder
- Trial name
- NCT04007666
- Testing
- Cognitive Processing Therapy, Control Group
- Where
- 2 sites in United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Perinatal Mental Health, Reproductive Behavior
Women's Reproductive Choices and Mental Health During Pregnancy and After Birth in Wartime Ukraine
The goal of this observational study is to learn how war affects reproductive decisions and perinatal mental health in Ukrainian women.
- Conditions
- Perinatal Mental Health, Reproductive Behavior, Women, Cohort Studies
- Trial name
- NCT07551934
- Testing
- Psychological Assessment, Routine Clinical Data Collection
- Where
- Ukraine
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Taras Shevchenko National University of Kyiv
Post Traumatic Stress Disorder, PTSD
Community-Based Telemedicine to Reduce Risk to Georgia Veterans With Post Traumatic Stress Disorder
The investigator proposes to examine treatment for Posttraumatic Stress Disorder for Veterans who served in Iraq and Afghanistan provided through telemedicine which connects patients to doctors in different locations using the…
- Trial name
- NCT01623219
- Testing
- Prolonged Exposure Therapy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
Stress Disorders, Post-Traumatic
Alterations of Gut Microbiome in the Frontline Medical Staff Under the Stress
With the outbreak of 2019 novel coronavirus (2019-nCoV), the frontline medical workers faced enormous stress, including a high risk of infection and inadequate protection from contamination, isolation, patients with negative…
- Trial name
- AGMFMSS (NCT04443075)
- Testing
- faecal sample collector
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Trauma, Posttraumatic Stress Disorder
Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (Pilot)
One of the most common and widely disseminated trauma treatments is Trauma Focused Cognitive Behavioral Therapy (TF-CBT). TF-CBT is a therapist-led, structured and sequential intervention, with treatment organized around…
- Trial name
- NCT07396935
- Testing
- Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
PTSD, Trauma, Psychological
Narrative Exposure Therapy for Adults With Intellectual Disability
The purpose of the study is to identify how Narrative Exposure Therapy (NET) can be adapted for delivery with adults with mild Intellectual Disability (ID) and to explore whether NET can reduce symptoms of traumatic stress in…
- Trial name
- NCT04418752
- Testing
- Psychological therapy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nottingham
Trauma, Psychological, Moral Injury
Wellness Intervention for Nurses Post Traumatic Growth and Selfcare
Nurses working in home and hospice care settings find their roles emotionally challenging and are at high risk for trauma, strain and fatigue. Such sufferings were high among nurses during the Covid-19 pandemic.
- Conditions
- Trauma, Psychological, Moral Injury, Compassion Fatigue
- Trial name
- WINGS (NCT06674876)
- Testing
- Blog writing
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Purdue University
Post Traumatic Stress Disorder
Department of Defense PTSD Adaptive Platform Trial - Intervention D - SLS-002
This is a Phase 2 randomized, double-blinded, placebo-controlled study that will evaluate multiple potential pharmacotherapeutic interventions for Post Traumatic Stress Disorder (PTSD) utilizing an adaptive platform trial (APT)…
- Trial name
- NCT06816433
- Testing
- Intervention D SLS-002
- Where
- 9 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Global Coalition for Adaptive Research
Posttraumatic Stress Disorder
A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD
Posttraumatic Stress Disorder (PTSD) remains a salient and debilitating problem, in the general population and for military veterans in particular.
- Trial name
- NCT04961190
- Testing
- Prolonged Exposure Therapy, Pharmacotherapy with paroxetine or venlafaxine XR
- Where
- 7 sites in United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Post Traumatic Stress Disorder
Neural Control and Cardiac-Vascular Function in Women With PTSD (VA Psychological Assessment)
The purpose of this research is 1) to investigate the role of the sympathetic nervous system and cardiac-vascular function in women with PTSD; and 2) to determine whether lifestyle modifications (exercise training and healthy…
- Trial name
- NCT03929939
- Testing
- Exercise training and healthy eating (overseen by IEEM research team)
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- North Texas Veterans Healthcare System
Anxiety Disorder/Anxiety State
Online Acceptance and Commitment Therapy for Reducing Anxiety
The main objective of this study is to test the effectiveness of an Internet-delivered Acceptance and Commitment Therapy (ACT) program in reducing anxiety symptoms.
- Trial name
- NCT03074669
- Testing
- ACT program
- Where
- Romania
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- West University of Timisoara
Chronic Pain, Anxiety
Phase II Trial of Nu-V3 Non-Invasive Nerve Stimulation Device for Chronic Pain, Anxiety, Depression, Sleeplessness
This Nu-V3 clinical study is a randomized, phase II, open-label study evaluating the Nu-V3 cranial nerve stimulation treatment device in patients with chronic pain, anxiety, depression, and/or sleeplessness.
- Conditions
- Chronic Pain, Anxiety, Depression, Sleeplessness
- Trial name
- Nu-V3P2RCT (NCT05394545)
- Testing
- Nu-V3
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nu-Life Solutions
Diabetes, Depression
Self-Efficacy Enhancing Interviewing Techniques Study
Patient self-efficacy, or confidence in one's ability to take the necessary steps to achieve a goal, has been shown to influence a number of important health behaviors and outcomes.
- Conditions
- Diabetes, Depression, Anxiety, Asthma
- Trial name
- SEE-IT (NCT00643435)
- Testing
- Self-efficacy enhancing interviewing techniques training, Control intervention
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Post Traumatic Stress Disorder
Technology-Based Tools to Enhance Quality of Care in Mental Health Treatment
Nearly 9 million U.S. children (1 in 8) meet criteria for at least one mental health disorder at any point in time. Effective treatments exist for these disorders, but children and families who seek services rarely receive them…
- Trial name
- NCT01915160
- Testing
- eTF-CBT, TF-CBT
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina