Clinical trials: Post-Traumatic Stress Disorders
Mild Traumatic Brain Injury
Deployment Related Mild Traumatic Brain Injury (mTBI)
The study will provide evidence on the long term outcomes of mTBI in service members returning from Afghanistan and Iraq. In addition, the study will provide evidence on mTBI incidence, and symptom patterns.
- Trial name
- NCT01847040
- Where
- 2 sites in United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- The Defense and Veterans Brain Injury Center
Anxiety, Posttraumatic Stress Disorder
School-based Practices in Arts and Resilience for Kids
This proposal will implement and test feasibility and efficacy of school-based art therapy and yoga/mindfulness programming to reduce mental health disparities and foster resilience in youth.
- Conditions
- Anxiety, Posttraumatic Stress Disorder, Trauma
- Trial name
- SPARK (NCT06945497)
- Testing
- Art Therapy, Yoga/Mindfulness
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Posttraumatic Stress Disorder, Insomnia
Stress, Sleep and Cardiovascular Risk
We are evaluating a model where trauma exposure and threatening environments elicit nocturnal vigilance and sleep-related fears that compromise the healthy reduction of autonomic arousal during sleep which in turn stimulates…
- Trial name
- NCT03487991
- Testing
- Personalized sleep intervention
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Howard University
Post Traumatic Stress Disorder, Childbirth Experience
"Connected Caesarean Section": Creating a Virtual Link Between Mothers and Their Infants to Improve Maternal Childbirth Experience: A Pilot Trial
One third of mothers rate their childbirth as traumatic. The prevalence of childbirth-related posttraumatic stress disorder (CB-PTSD) is of 4.7% and the prevalence of childbirth-related posttraumatic stress symptoms (CB-PTSS) of…
- Trial name
- e-motion-pilot (NCT05319665)
- Testing
- Head-mounted display
- Where
- Switzerland
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction
Trifecta Research Study
This observational study evaluates the impact of Ibogaine-Magnesium (IM), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), Magnetic e-Resonance Therapy (MeRT), and Physiological Supplementation (PS) on posttraumatic stress disorder…
- Conditions
- PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction, Brain Injury, Depression - Major Depressive Disorder
- Trial name
- NCT07717866
- Testing
- Magnetic e-Resonance Therapy (MeRT), Ibogaine Hydrochloride with Magnesium Sulfate, 5-methoxy-N,N-dimethyltryptamine
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Axial Therapeutic Research
Post-Traumatic Stress Disorder
Effect of Propranolol on Preventing Posttraumatic Stress Disorder
This study will assess the effectiveness of taking propranolol soon after a traumatizing incident in reducing the incidence and severity of posttraumatic stress disorder in acutely traumatized individuals.
- Trial name
- NCT00158262
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Post Traumatic Stress Disorder
Observational Study of the Evaluation of Post Traumatic Stress Post Stroke
This prospective, observational, multicentre study evaluates the existence of Post-traumatic stress disorder following a stroke at 3 and 6 months after the management of the patient.
- Trial name
- SPTD (NCT04299841)
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- CHI MONT DE MARSAN ET PAYS DES SOURCES
Child Sexual Abuse, Post-Traumatic Stress Disorder, PTSD
Intensive Inpatient Trauma-Focused Cognitive Behavioral Therapy (II-TF-CBT) for Adolescents With PTSD Following Sexual Abuse
This study looks at a treatment program for children and teens who have post-traumatic stress disorder (PTSD) after sexual abuse. The program is called II-TF-CBT.
- Trial name
- NCT07732335
- Testing
- II-TF-CBT
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Chronic Pain, PTSD
Management of Chronic Pain and PTSD in Gulf War Veterans With tDCS+Prolonged Exposure
Gulf War Veterans (a DoD/VA defined service era corresponding to the first Gulf War under operations Desert Storm and Desert Shield 1990-1991), especially those who present with Post-Traumatic Stress Disorder (PTSD), are…
- Trial name
- NCT04236284
- Testing
- Home-based tDCS, Prolonged Exposure Therapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Post-Traumatic Stress Disorder
Neural Correlates of Cognitive Rehabilitation in Post-Traumatic Stress Disorder (PTSD)
Post Traumatic Stress Disorder (PTSD) is an emotional disorder that can also lead to problems with attention and memory. Cognitive training has been successfully used to improve attention and processing speed in other patient…
- Trial name
- NCT00928941
- Testing
- cognitive training, video game
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Mental Disorders, Psychological Trauma
Hospital Cohort Survey of Public Health Post-attack of July 14, 2016
The terrorist attack on the ram truck, which occurred on 14 July 2016 on the Promenade des Anglais in Nice, involved a significant number of casualties in the civilian population: 86 dead including 10 children and adolescents…
- Trial name
- ECHOS (NCT03353805)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Intrusive Thought, Psychological Trauma
Towards a Post-exposition Pharmacological Prophylaxis for Post-traumatic Stress Disorder
In this study, we investigate the role that deep sleep plays in the prevention of posttraumatic stress disorder after someone has been exposed to a trauma by boosting deep sleep with two drug conditions compared to placebo…
- Conditions
- Intrusive Thought, Psychological Trauma, Inflammatory Response, Physiological Stress
- Trial name
- TRAUMA-PRO (NCT04508166)
- Testing
- Dexmedetomidine, Gamma-Hydroxybutyrate, Experimental Model Trauma Film
- Where
- Switzerland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Psychiatric University Hospital, Zurich
Stress Disorders, Post-Traumatic
Propranolol Reactivation Mismatch (PRM) Treatment for PTSD
The aim of the proposed work is to gather pilot data from an attempt to enhance the ability of propranolol reactivation (PR) to improve PTSD symptoms by incorporating into the design a mismatch (PRM) between what is expected and…
- Trial name
- NCT03652922
- Testing
- Reactivation Mismatch
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Post Traumatic Stress Disorder, Sleep Deprivation
Explanation About Sleep in Post Trauma Patients
This study is designed to test the effect of an explanation about the first sleep following trauma exposure, on the development of Post Traumatic Stress Disorder (PTSD) in the months following the traumatic event.
- Trial name
- NCT01684085
- Testing
- Explanation encouraging sleep, Explanation discouraging sleep, Lorazepam
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Psychological Trauma, PTSD
Study of Yoga and Mindfulness for Psychological and Physical Wellness
The study rationale is to analyze the extent to which adult U.S. or non U.S. veterans or active duty military personnel who participate in the Yoga for Men (YfM) online Yoga and meditation classes report changes in symptoms of…
- Trial name
- NCT03059095
- Testing
- Yoga & Meditation
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Post Traumatic Stress Disorder, Alcohol Use Disorder
FAAH Availability in Psychiatric Disorders: A PET Study
The aim of the present study is to examine Fatty Acid Amide Hydrolase (FAAH) availability in humans, including healthy individuals and across a spectrum of psychiatric disorders in which alterations in the endocannabinoid system…
- Conditions
- Post Traumatic Stress Disorder, Alcohol Use Disorder, Psychosis
- Trial name
- NCT04404712
- Testing
- [11C]MK-3168
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Yale University
Post Traumatic Stress Disorder
Neural Control and Cardiac-Vascular Function in Women With PTSD (VA Psychological Assessment)
The purpose of this research is 1) to investigate the role of the sympathetic nervous system and cardiac-vascular function in women with PTSD; and 2) to determine whether lifestyle modifications (exercise training and healthy…
- Trial name
- NCT03929939
- Testing
- Exercise training and healthy eating (overseen by IEEM research team)
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- North Texas Veterans Healthcare System
Healthy, Stress, Psychological
Study of Physical Health for Women With Posttraumatic Stress or Depression
The purpose of this study is to obtain a better understanding of how stress is related to health risks.
- Conditions
- Healthy, Stress, Psychological, Depression, Posttraumatic Stress Disorders
- Trial name
- NCT01208844
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University