Clinical trials: Post-Traumatic Stress Disorders
Alzheimer's Disease, Mild Cognitive Impairment
Retinal Imaging in Neurodegenerative Disease
This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (UWF) fundus photography to assess the structure and function of the…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, Multiple Sclerosis
- Trial name
- NCT03233646
- Testing
- Retinal and Choroidal Imaging
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Stress Disorders, Post-Traumatic
Effects of Equine Assisted Activities on Veterans With Post-traumatic Stress Disorder
The study will examine the effects of eight weeks of equine assisted activities (EAA) on co-regulation, basal physiological values, and symptom severity in veterans with post-traumatic stress disorder (PTSD).
- Trial name
- NCT04850573
- Testing
- equine assisted activities
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Myocardial Infarction
Anxiety, Stress and Pain & Myocardial Infarction
People often experience the acute phase of a myocardial infarction as a stressful and traumatic event that seems lifethreatening.
- Trial name
- NCT04130269
- Testing
- No intervention
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
HIV, Depression
An HIV Intervention for Black Men at Risk - The Enhanced Sexual Health Intervention for Men (ES-HIM)
HIV continues to spread among Black men who have sex with men (MSM), but few interventions target high-risk Black men who have sex with men and women (MSMW).
- Conditions
- HIV, Depression, Posttraumatic Stress Disorder
- Trial name
- ES-HIM (NCT01641146)
- Testing
- Enhanced Sexual Health Intervention for Men (ES-HIM), Health Promotion (HP) Comparison Arm
- Where
- 4 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
PTSD
Aripiprazole Augmentation of Antidepressants in PTSD
The proposed investigation will determine the therapeutic potential of aripiprazole augmentation to a stable antidepressant regimen for reducing posttraumatic stress disorder (PTSD) symptoms, cognitive symptoms, psychotic…
- Trial name
- NCT00489866
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Durham VA Medical Center
Psychological Trauma, Historical, Nutrition
Nutrition for Trauma Community Survey
The survey will help investigators learn everything about how people view and respond to trauma from a holistic perspective through body (nutrition), mind (mental health rejuvenation and renewal), and spirit (faith-based) lens.
- Conditions
- Psychological Trauma, Historical, Nutrition, PTSD - Post Traumatic Stress Disorder
- Trial name
- N4T (NCT06864637)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- True Paleo Inc.
Asthma, Hypertension
World Trade Center Adolescent Health Study
The proposed study builds upon preliminary studies in self-selected populations to identify opportunities for early identification of World Trade Center-related health consequences in adolescents.
- Conditions
- Asthma, Hypertension, Cardiovascular Risk Factor, Insulin Resistance
- Trial name
- NCT02068183
- Where
- United States
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Post Traumatic Stress Disorder
Using Mobile Technology to Address the Trauma Mental Health Treatment Gap
BounceBack Now (BBN) is a self-help, trauma-focused mental health mobile application (app) with automated assessment with treatment guidance and in-app evidence-based treatment support for depression, post-traumatic stress…
- Trial name
- NCT05374408
- Testing
- Aim 2: BounceBack Now (BBN) for Trauma Informed Care Deployment, Aim 1 Participant Focus Groups, Aim 1 BHP Focus Groups
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Postpartum Complication, Posttraumatic Stress Symptoms
Labor Education to Reduce Postpartum Traumatic Stress
The goal of this randomized controlled trial is determine if education on common events in labor in nulliparous women can reduce the postpartum traumatic symptoms.
- Trial name
- LEPT (NCT06992791)
- Testing
- Prenatal Education on Childbirth
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Posttraumatic Stress Disorder, Insomnia
Stress, Sleep and Cardiovascular Risk
We are evaluating a model where trauma exposure and threatening environments elicit nocturnal vigilance and sleep-related fears that compromise the healthy reduction of autonomic arousal during sleep which in turn stimulates…
- Trial name
- NCT03487991
- Testing
- Personalized sleep intervention
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Howard University
Mental Disorders, Domestic Violence
NET in Iranian Women Suffering From Post Traumatic Stress Symptoms
The proposed study seeks to investigate to what extent Narrative Exposure Therapy (NET) is an effective treatment for the reduction of symptoms of Post-Traumatic Stress Disorder (PTSD) and depression and for the improvement of…
- Trial name
- NCT01731418
- Testing
- Narrative Exposure Therapy, Treatment-as-usual
- Where
- Iran
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Posttraumatic Stress Disorder
Fear Potentiation and Fear Inhibition in Posttraumatic Stress Disorder
The current study will investigate the ability of people with and without fear symptoms after trauma to inhibit fear in an experimental situation.
- Trial name
- NCT00209040
- Testing
- Acoustic Startle Testing
- Where
- United States
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Emory University
Stress Disorders, Post-Traumatic
Implementation of CPT for PTSD in Diverse Communities
Aim: To identify, assess, and address organizational context and provider-level barriers and facilitators of implementation of Evidence-based treatments (EBTs) using a mixed-methods approach in a diverse community mental health…
- Trial name
- NCT01702168
- Testing
- Provider training: Cognitive Processing Therapy (CPT)
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Peripheral Vascular Diseases
Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 2
The purpose of this research study is to examine the effect of various forms of exercise training on blood vessel function in healthy individuals as well as individuals with mental health disorders (posttraumatic stress disorder…
- Trial name
- NCT04922762
- Testing
- Moderate Intensity, Normal Volume Exercise Training, High Intensity, Normal Volume Exercise Training, Moderate Intensity, High Volume Exercise Training
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Mental Health Disorders
Examining the Effect of Mental Health Disorders on Vascular Function and Exercise Tolerance
Specific Aim #1: Examining the impact of mental health disorders (PTSD and GAD) on peripheral vascular function and sympathetic nervous system activity in young individuals.
- Trial name
- NCT03216980
- Testing
- PTSD/GAD Antioxidant, Healthy Control Antioxidant
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Mental Health, Depression
Designing a Mobile App to Support Academic Success for Student Veterans
Compared to civilian students in higher education, student Veterans have high rates of mental health disorders (e.g., Depression: 24% vs 12.1%).
- Conditions
- Mental Health, Depression, Post-Traumatic Stress Disorder, Anxiety
- Trial name
- NCT05344092
- Testing
- VetEd Mobile Application
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post-traumatic Stress Disorder (PTSD), Trauma
Functional Brain Imaging in PTSD
Patients with post-traumatic stress disorder (PTSD) have abnormalities in the function of the amygdala and medial prefrontal cortex (particularly anterior cingulate), in addition to abnormalities of hippocampal volume.
- Trial name
- NCT02053532
- Testing
- Positron emission tomography/magnetic resonance imaging
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Post Traumatic Stress Disorder, Cardiovascular Diseases
NightWare and Cardiovascular Health in Women With PTSD
The purpose of this study is to determine whether NightWare therapeutic intervention improves biomarkers of vascular and renal function in premenopausal women with PTSD-related nightmares, and examine whether these improvements…
- Conditions
- Post Traumatic Stress Disorder, Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness
- Trial name
- NCT07021014
- Testing
- NightWare
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
PTSD
Using Heart Rate Variability Biofeedback to Improve Attention and Memory in PTSD+ Combat Veterans
This study will test the effectiveness of Heart Rate Variability (HRV) Biofeedback as a therapeutic tool in the reduction of everyday memory problems routinely experienced by combat veterans with Posttraumatic Stress Disorder…
- Trial name
- HRVB (NCT00625105)
- Testing
- Biofeedback
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- William Jennings Bryan Dorn VA Medical Center
Post Traumatic Stress Disorder
Department of Defense PTSD Adaptive Platform Trial - Intervention A - Fluoxetine
This is a Phase 2 randomized, double-blinded, placebo-controlled study that will evaluate multiple potential pharmacotherapeutic interventions for PTSD utilizing an adaptive platform trial design.
- Trial name
- NCT05948553
- Testing
- Intervention A Fluoxetine Hydrochloride (HCl)
- Where
- 9 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Global Coalition for Adaptive Research