Clinical trials: Post-Traumatic Stress Disorders
PTSD, Depression
Violence Prevention for Adolescent Girls With Prior Maltreatment
The purpose of the study is to adapt and test an evidence-based trauma treatment program for adolescent girls with histories of child maltreatment.
- Conditions
- PTSD, Depression, Aggression, Victimization
- Trial name
- GAIN (NCT02765048)
- Testing
- GAIN Program
- Where
- 3 sites in United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
PTSD
Monoamine Transporters Genotypes: Risk of PTSD and Related Comorbidities
Dr. Wang's merit review is aimed at providing a better understanding of the relationship between SLC6A3/SLC6A4 and the mental health of veterans exposed to high levels of combat stress, specifically focusing on PTSD symptoms…
- Trial name
- MTG (NCT00403455)
- Testing
- Paroxetine
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PTSD, Post-traumatic Stress Disorder
Network-based Neurofeedback in PTSD
This project will examine the use of real-time fMRI (rt-fMRI) neurofeedback in the regulation of neural networks underlying symptoms experienced by individuals with posttraumatic stress disorder (PTSD).
- Trial name
- NCT04875221
- Testing
- Connectivity-based neurofeedback
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Anxiety Disorders, Post Traumatic Stress Disorder
Increasing Treatment Efficacy Using SMART Methods for Personalizing Care
The proposed study will determine the feasibility, tolerability, and acceptability of a study that tests: 1) personalized treatment delivery (i.e., module sequencing and treatment discontinuation timing) aimed at increasing the…
- Conditions
- Anxiety Disorders, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT04642898
- Testing
- Standard UP Treatment, Capitalization UP Treatment, Compensation UP Treatment
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Posttraumatic Stress Disorder
Measurement of Pituitary Volume and Hormonal Changes in Patients With Post-traumatic Stress Disorder
Approximately, post-traumatic stress disorder (PTSD) occurs in 8% of the adult population over time. Exposure to traumatic events increases the risk of poor physical health and often leads to disability.
- Trial name
- NCT00815204
- Testing
- MRI of the pituitary, DEX/CRH test
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Posttraumatic Stress Disorder
Suvorexant and Sleep's Benefits to Therapeutic Exposure for Posttraumatic Stress Disorder
The purpose of this study is to examine effects of blocking the orexin system with suvorexant after exposure-based intervention for posttraumatic stress disorder (PTSD) on sleep, PTSD symptoms, and intersession habituation.
- Trial name
- NCT02849548
- Testing
- suvorexant
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Howard University
Anxiety Disorders
Transdiagnostic Treatment for Anxiety Disorders in Two Cities of México
This study evaluates the effectiveness of The Unified Transdiagnostic Protocol, a psychological treatment for the intervention of a broad range of anxiety disorders.
- Trial name
- NCT03916315
- Testing
- Transdiagnostic Treatment
- Where
- 2 sites in Mexico
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Post-traumatic Stress Disorder (PTSD), Aggressive Behavior
Prevention of Post-Traumatic Stress Disorder in Soldiers
Soldiers in conflict or former conflict regions deployed in peace-keeping missions were and are often exposed to multiple traumatic events and situations in which they are forced to engage in violent behavior.
- Trial name
- NCT01729325
- Testing
- Preventive Narrative Exposure Therapy
- Where
- Burundi
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Stress Disorders, Post-Traumatic
Neurophysiological and Neuropsychological Evalution in Healthcare Workers
The goal of this observational study is to compare in participant population the effect of stress condition on cerebral EEG activity Participants will do an 8 minutes EEG registration.
- Trial name
- EEGCOV (NCT06368999)
- Testing
- EEG
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Chronic Pain, Anxiety
Phase II Trial of Nu-V3 Non-Invasive Nerve Stimulation Device for Chronic Pain, Anxiety, Depression, Sleeplessness
This Nu-V3 clinical study is a randomized, phase II, open-label study evaluating the Nu-V3 cranial nerve stimulation treatment device in patients with chronic pain, anxiety, depression, and/or sleeplessness.
- Conditions
- Chronic Pain, Anxiety, Depression, Sleeplessness
- Trial name
- Nu-V3P2RCT (NCT05394545)
- Testing
- Nu-V3
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nu-Life Solutions
Stress Disorders, Post-Traumatic
Violence and Stress Assessment (ViStA) Project to Improve Post Traumatic Stress Disorder Management in Primary Care
The purpose of this study is to conduct a randomized trial of a Post Traumatic Stress Disorder (PTSD) Care Management (PCM) program to detect, treat, and improve PTSD treatment processes and outcomes in patients seeking primary…
- Trial name
- ViStA (NCT01401101)
- Testing
- PCM, MEU
- Where
- 7 sites in United States
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- RAND
PTSD - Post Traumatic Stress Disorder, Depression/Anxiety
An Integrative, Digital Health Approach to Veteran-Centered PTSD Care
The goal of this study is to test the effectiveness of a stress self-management mobile health system (smartphone app + wearable sensor) alongside an intense physical cycling intervention to reduce symptoms of stress in a veteran…
- Trial name
- NCT06993012
- Testing
- Mobile Health Stress Self Management System, Intensive Cycling Activity
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Mental Health, Depression
rTMS for Emotional Difficulties in Verterans
Mental illness rarely occurs as a single, easily categorized condition. Instead, multiple disorders often co-occur. This complicates the treatment plan for many Veterans, especially those suffering the most severe dysfunction.
- Conditions
- Mental Health, Depression, rTMS, Anxiety
- Trial name
- rTMS (NCT03749967)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post-traumatic Stress Disorder
Psychophysiologic Predictors of Post-deployment Mental Health Outcomes
The primary objectives of this proposal are to develop objective pre-deployment predictors of PTSD and test two pre-deployment resiliency interventions.
- Trial name
- NCT00838006
- Testing
- heart rate variability biofeedback, Cognitive bias modification training
- Where
- United States
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Biomedical Research Foundation
PTSD, Sleep Disorder
Sleep Impairments in Refugees Diagnosed With PTSD
The aim of this study is to examine sleep architecture in refugees with PTSD. Polysomnography (PSG) will be carried out to study the occurrence of sleep disorders in patients and healthy controls.
- Trial name
- PSG-PTSD (NCT03535636)
- Testing
- Polysomnography
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
PTSD
Evaluation of Web-Based CBT for Rape Victims
Rape is unfortunately a common experience among women, affecting between 13 and 20%. In addition, up to 50% of all rape victims experience significant and persistent psychological distress.
- Trial name
- NCT02777294
- Testing
- Online intervention, Psycho-educational website
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- East Carolina University
PTSD
Psychometric Evaluation of a Dutch Attribution Questionnaire for Trauma-Related Attributions
A newly developed Dutch-language questionnaire was designed to assess trauma-related attributional styles across four theoretically derived dimensions: locus of causality, controllability, stability, and globality.
- Trial name
- PEDAQTRA (NCT07469930)
- Where
- Netherlands
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- Reinier van Arkel
Stress Disorders, Post-Traumatic, Depressive Disorder, Major
The Effect of Traumatic Childbirth on the Incidence of PTSD and Other Major Postpartum Psychopathology
Determination of incidence and prevalence of PTSD and other types of psychopathology (such as anxiety and affective disorders) after traumatic birth experiences and elucidation of salient risk factors in the local population…
- Trial name
- NCT02370576
- Testing
- rating scale application
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Post Traumatic Stress Disorder, Traumatic Brain Injury
Non-invasive Nerve Stimulation for PTSD and Sleep
In this study, our objective is to determine the effect of two different nerve stimulation types in changing sleep architecture.
- Trial name
- NCT03170440
- Testing
- Transcutaneous nerve stimulation location 1
- Where
- 3 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- University of Florida
PTSD
Pilot Evaluation of AboutFace: Novel Peer Education Resource for Veterans
The purpose of this study is to evaluate the AboutFace peer education website for the purpose of reducing stigma and improving attitudes toward seeking mental health services among Veterans.
- Trial name
- NCT02486692
- Testing
- AboutFace Website
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development