Clinical trials: Post-Traumatic Stress Disorders
Stress, Psychological, Sleep Disturbance
The Effect of a Combined Nature-based and Virtual Mindfulness Intervention on Perceived Stress in Healthcare Workers
Rationale: Healthcare workers that care for patients with COVID-19 are at increased risk for stress-related symptoms. When these symptoms are chronic, they can result in burnout and other mental health conditions that can…
- Conditions
- Stress, Psychological, Sleep Disturbance, Burnout, Caregiver, Posttraumatic Stress Disorder
- Trial name
- NCT04846790
- Testing
- Nature Only, Nature+Mindfulness
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Post Traumatic Stress Disorder
Feasibility Trial of Narrative Exposure Therapy (NET) for Posttraumatic Stress Disorder (PTSD) During Pregnancy
Posttraumatic stress disorder (PTSD) affects up to 35% of pregnant trauma survivors. Moreover, prenatal PTSD rates are up to 4 times higher among communities of color compared to white populations.
- Trial name
- NET (NCT04525469)
- Testing
- Narrative Exposure Therapy
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Post-traumatic Stress Disorder, Depressive Disorder
Project SERVE: Post Deployment Functioning
Functional recovery is of the utmost importance to evaluate in our returning Operation Enduring and Iraqi Freedom Veterans so that we can better understand their needs and experiences during the readjustment process from warzone…
- Conditions
- Post-traumatic Stress Disorder, Depressive Disorder, Alcoholism
- Trial name
- NCT01123642
- Where
- United States
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post-traumatic Stress Disorder (PTSD)
Prospective Cohort Study of Accelerated Resolution Therapy (ART) for Treatment of Military Psychological Trauma
This is a prospective cohort treatment intervention study (n=200) whereby U.S. service members and veterans with symptoms of PTSD will undergo 2-5 sessions of ART delivered by Florida licensed mental health professionals trained…
- Trial name
- NCT02030522
- Testing
- Accelerated Resolution Therapy (ART)
- Where
- 8 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Posttraumatic Stress Disorder, Substance Use Disorders
Treating Violence-related PTSD and Substance Risk in Low-income, Urban Adolescents
This project will provide initial feasibility and efficacy data for the implementation of Narrative Exposure Therapy (NET) to urban, at-risk youth.
- Trial name
- POWER-NET (NCT03737383)
- Testing
- Narrative Exposure Therapy
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Complex Posttraumatic Stress Disorder (cPTSD), Dissociative Disorder Not Otherwise Specified (DDNOS)
Emotional and Cognitive Self-regulation, an EEG Study
The main goal of the proposed project is to assess treatment-induced changes of electrophysiological and psychophysiological correlates of the capacity to regulate emotion, executive functions, and clinical measures in…
- Conditions
- Complex Posttraumatic Stress Disorder (cPTSD), Dissociative Disorder Not Otherwise Specified (DDNOS), Dissociative Identity Disorder (DID)
- Trial name
- ECSR (NCT02459340)
- Testing
- therapeutic treatment (inpatient and outpatient setting)
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yolanda Schlumpf, PhD
Intrusive Memories, PTSD
The Effect of Oxytocin on the Consolidation of Trauma-Associated Memories
The purpose of the study is to examine whether oxytocin and certain polygenic risk scores affect the development of intrusive memories, a cardinal symptom of PTSD.
- Trial name
- NCT03875391
- Testing
- Oxytocin
- Where
- Germany
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Psychosis;Schizophrenic, Personality Disorders
The Impact of the COVID-19 (SARS-CoV-2 Disease) on Psychopathology
The outbreak of the SARS-CoV-2 pandemic may be considered a traumatic phenomenon. In a sample of subjects suffering from different psychiatric disorders, psychopathological status and Post-Traumatic Stress Disorder (PTSD)…
- Conditions
- Psychosis;Schizophrenic, Personality Disorders, Mood Disorders, Anxiety Disorders
- Trial name
- NCT04694482
- Testing
- Psychometric scale administration
- Where
- Italy
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Alcohol Use Disorder, PTSD
Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder
The project will examine whether a computerized neuroscience-based cognitive training program can improve cognitive functioning and recovery outcomes among Veterans with Alcohol Use Disorder and co-occurring PTSD.
- Conditions
- Alcohol Use Disorder, PTSD, Cognitive Dysfunction
- Trial name
- NCT02929979
- Testing
- Cognitive Training
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PTSD
Is Olfaction the Key to PTSD
Participants arriving to the ED following a potentially traumatic event such as a motor vehicle accident will be recruited into the study.
- Trial name
- NCT05640882
- Testing
- VRET, VRET OLFACTION
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
Stress Disorders, Post-Traumatic, Stress Related Disorder
Mindfulness-SOS for Refugees
Worldwide, refugees and asylum seekers suffer at high rates from trauma and stress-related mental health problems. The research group therefore developed, and initially piloted in a single-site open trial, a novel mindfulness…
- Trial name
- NCT05616286
- Testing
- Mindfulness-SOS for Refugees
- Where
- Israel
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Posttraumatic Stress Disorder
Safety & Efficacy Study Using Topiramate in Posttraumatic Stress Disorder
The purpose of this study was to determine if Topiramate was safe and effective for use in civilian subjects with Posttraumatic Stress Disorder.
- Trial name
- NCT00204386
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Substance-Related Disorders, Depression
Wraparound for High-risk Families with Substance Use Disorders: Examining Family, Child, and Parent Outcomes
The investigators propose a Hybrid Type 1 effectiveness-implementation quasi-experimental trial. Participants are drawn from two different communities contemporaneously.
- Conditions
- Substance-Related Disorders, Depression, Stress Disorders, Post-Traumatic, Child Abuse
- Trial name
- NCT04637581
- Testing
- Wraparound
- Where
- 4 sites in United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
PTSD, Psychiatric Illness
Killing Pain - Use of Analgesic, Sedative and Anxiolytic Medication and the Development of Psychiatric Illness in Adolescents
Prescription of analgesic, sedative, and anxiolytic medication for children and adolescents is increasing in Western countries. In recent decades, rates have also increased in Norway, despite a relatively restrictive prescription…
- Conditions
- PTSD, Psychiatric Illness, Prescription Drug Dependence, Addiction
- Trial name
- NCT04336605
- Testing
- Age & Development, Socioeconomy, Traumatic Events
- Where
- Norway
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Depression, Posttraumatic Stress Disorder
Evaluation of Outcomes Following Surf Therapy
The current study evaluates psychological and physical health outcomes for active-duty service members following participation in an established surf therapy program.
- Trial name
- NCT02857751
- Testing
- Surf therapy
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Post-traumatic Stress Disorder, Depression
Randomized Control Trial of Group Intervention With Former War-affected Boys in the Democratic Republic of Congo
The purpose of this study is to evaluate, in a randomised control trial (RCT), the effectiveness of group-based, trauma-focused Cognitive Behaviour Therapy (TF-CBT) in reducing psychological distress in former child soldiers and…
- Conditions
- Post-traumatic Stress Disorder, Depression, Conduct Disorder
- Trial name
- NCT01494831
- Testing
- TF-CBT
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Depression, Anxiety, PTSD
A Scalable Model for Promoting Functioning and Well-Being Among Veterans With a History of Mental Health Challenges Via Meaningful Social Interactions: Project V-SPEAK!
The goal of this study is to refine and test a strategy for engaging veterans with symptoms of depression and/or anxiety as volunteers to help English language learners (ELLs) improve their speaking skills via structured…
- Trial name
- V-SPEAK! (NCT05506839)
- Testing
- Intervention (videoconferencing)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Stress Disorders, Post-Traumatic
Alterations of Gut Microbiome in the Frontline Medical Staff Under the Stress
With the outbreak of 2019 novel coronavirus (2019-nCoV), the frontline medical workers faced enormous stress, including a high risk of infection and inadequate protection from contamination, isolation, patients with negative…
- Trial name
- AGMFMSS (NCT04443075)
- Testing
- faecal sample collector
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
PTSD, Intrusive Memories
Estradiol and Intrusive Memories
The aim of the current project is to investigate the impact of 3mg of oral estradiol valerate on the formation of intrusive memories after analog trauma.
- Conditions
- PTSD, Intrusive Memories, Intrusion Symptom, Trauma
- Trial name
- EstraMemo (NCT07419594)
- Testing
- Estradiol Valerate
- Where
- Germany
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany