Clinical trials: Post-Traumatic Stress Disorders
Stress Disorders, Post-Traumatic
Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV
The purpose of this study is to find out why patients with post-traumatic stress disorder (PTSD) have an increased risk for heart disease and high blood pressure later in life.
- Trial name
- ANG-P (NCT02560805)
- Testing
- Microneurography, Combat virtual reality video clip, Handgrip Exercise
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Emory University
Stress, Depression
Mission Reconnect: Promoting Resilience and Reintegration of Post-Deployment Veterans and Their Families
An urgent and growing need exists for interventions that support the long-term adjustment and mental health needs of OIF/OEF veterans and their relationship partners after the return from deployment.
- Conditions
- Stress, Depression, PTSD, Sleep
- Trial name
- NCT01680419
- Testing
- Mission Reconnect, PREP
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Collinge and Associates, Inc.
PTSD
Supported Education Pilot
The goal of this project is to gather data necessary for a full scale trial of a supported education service for OIF/OEF veterans with PTSD.
- Trial name
- SEd (NCT01073657)
- Testing
- Supported Education, General Peer Support
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Delirium, Anxiety
Patient- and Family-centred Care in the Adult Intensive Care Unit: a Feasibility Study
Background: In the intensive care unit (ICU), delirium in patients and long-term mental health challenges in both patients and their family members are highly prevalent.
- Conditions
- Delirium, Anxiety, Post Intensive Care Unit Syndrome, Post Intensive Care Unit Syndrome Family
- Trial name
- FAM-ICU (NCT06974214)
- Testing
- FAM-ICU
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Post-traumatic Stress Disorder (PTSD), Aggressive Behavior
Prevention of Post-Traumatic Stress Disorder in Soldiers
Soldiers in conflict or former conflict regions deployed in peace-keeping missions were and are often exposed to multiple traumatic events and situations in which they are forced to engage in violent behavior.
- Trial name
- NCT01729325
- Testing
- Preventive Narrative Exposure Therapy
- Where
- Burundi
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Stress Disorders, Post-Traumatic
Implementation of CPT for PTSD in Diverse Communities
Aim: To identify, assess, and address organizational context and provider-level barriers and facilitators of implementation of Evidence-based treatments (EBTs) using a mixed-methods approach in a diverse community mental health…
- Trial name
- NCT01702168
- Testing
- Provider training: Cognitive Processing Therapy (CPT)
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
PTSD, PTSD Symptoms
Virtual Reality Treatment for Trauma Related to COVID-19 Infection
This clinical trial aims to develop and evaluate the effectiveness of virtual reality (VR)-based exposure therapy for trauma symptoms related to COVID-19 infection.
- Trial name
- NCT07213596
- Testing
- VR Exposure Therapy, Cognitive Behavioral Therapy (CBT), Supportive Psychotherapy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Aggression, Post Traumatic Stress Disorders
Strength at Home Couples Program (PTSD-Focused Relationship Enhancement Therapy for Returning Veterans)
The purpose of the project is to develop and test a couples-based relationship enhancement group intervention for married or partnered Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF)/Operation New Dawn (OND)…
- Trial name
- NCT00827879
- Testing
- Strength at Home Couples Group, Supportive Group Therapy
- Where
- 2 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Boston VA Research Institute, Inc.
Stress Disorders, Post-Traumatic, Depressive Disorder
Promoting Attachment Through Healing
Intimate partner violence (IPV) is a significant and pervasive public health challenge and is associated with mental illnesses such as depression, anxiety and posttraumatic stress disorder (PTSD).
- Conditions
- Stress Disorders, Post-Traumatic, Depressive Disorder, Anxiety Disorders
- Trial name
- PATH (NCT03536442)
- Where
- Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Post-traumatic Stress Disorder, Psychological Trauma
Prevalence of Post-traumatic Stress Disorder and Trauma Symptoms in a General Population Sample
The goal of this observational study is to learn about how many people have post-traumatic stress disorder and related symptoms in the general population of people without any mental illness in the Barcelona region of Catalonia…
- Trial name
- NCT05679245
- Testing
- Assessment for exposure to psychological trauma and related symptoms
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Post-Traumatic Stress Disorder in Children, Post-traumatic Stress Disorder
Adaptation of the PCIP for Children Aged 6 to 11
This study will implement a brief Post-traumatic Stress Disorder (PTSD) intervention for children, the Primary Care Intervention for PTSD (PCIP) delivered through telehealth (computer or smartphone delivery), to 10 youth age 6-11…
- Trial name
- NCT05606172
- Testing
- Primary Care Intervention for PTSD (PCIP) Youth aged 6 -11, Waitlist Treatment as Usual
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Stress Disorders, Post-Traumatic
Efficacy Study of Mindfulness-Based Exercise for Posttraumatic Stress Disorder (PTSD)
This study will explore the relationship between changes in plasma cortisol and symptom reduction resulting from individuals with posttraumatic stress disorder (PTSD) participating in an 8-week program of mindfulness-based…
- Trial name
- NCT01462045
- Testing
- Mindfulness-based exercise
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
PTSD
Using Heart Rate Variability Biofeedback to Improve Attention and Memory in PTSD+ Combat Veterans
This study will test the effectiveness of Heart Rate Variability (HRV) Biofeedback as a therapeutic tool in the reduction of everyday memory problems routinely experienced by combat veterans with Posttraumatic Stress Disorder…
- Trial name
- HRVB (NCT00625105)
- Testing
- Biofeedback
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- William Jennings Bryan Dorn VA Medical Center
Intervention Effectiveness, Practice-based Evidence
Strengthening Family Coping Resources Open Trials
Strengthening Families Coping Resources (SFCR) Open Trials completes the second stage of the National Institute on Drug Abuse's intervention development model by testing a new family, skills-based intervention involving pre-post…
- Conditions
- Intervention Effectiveness, Practice-based Evidence, Posttraumatic Stress Disorder
- Trial name
- SFCR (NCT01754610)
- Testing
- Strengthening Family Coping Resources (SFCR)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Mild Traumatic Brain Injury, Posttraumatic Stress Disorder
Imaging Biomarkers of Mild Traumatic Brain Injury: a Longitudinal Cohort Study
This longitudinal cohort study aims to detect the topographical nature of the white matter microstructure and resting state functional connectivity patterns across the whole brain in the evolution of pathology as a function of…
- Conditions
- Mild Traumatic Brain Injury, Posttraumatic Stress Disorder, Affective and Somatic Complaints, Cognitive Impairments
- Trial name
- NCT02868684
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Domestic Violence, Depression
Cortisol Evaluation in Abuse Survivors
This study looks at the biological effect of domestic violence and abuse (DVA) on women's mental health. The mechanisms through which DVA causes mental disorders are very poorly understood.
- Conditions
- Domestic Violence, Depression, Anxiety, Panic Disorder
- Trial name
- CEASE (NCT01632553)
- Where
- 2 sites in United Kingdom
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Bristol
HIV, Depression
An HIV Intervention for Black Men at Risk - The Enhanced Sexual Health Intervention for Men (ES-HIM)
HIV continues to spread among Black men who have sex with men (MSM), but few interventions target high-risk Black men who have sex with men and women (MSMW).
- Conditions
- HIV, Depression, Posttraumatic Stress Disorder
- Trial name
- ES-HIM (NCT01641146)
- Testing
- Enhanced Sexual Health Intervention for Men (ES-HIM), Health Promotion (HP) Comparison Arm
- Where
- 4 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Stress Disorders, Posttraumatic
Veteran Stress and Learning Study
This is a research study examining the use of two medications, Hydrocortisone and D-Cycloserine, compared to an inactive substance (placebo), on their ability to reduce fear responses and memory of fear in Veterans with symptoms…
- Trial name
- VSL (NCT00674570)
- Testing
- Hydrocortisone, D-Cycloserine
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Miscarriage
Interest of a Short Early Psychological Care in Women With Miscarriage
Miscarriage is a very common complication of pregnancy, accounting for 15.3% (95% CI 12.5-18.7%) of diagnosed pregnancies. Miscarriage would affect one in ten women during her lifetime.
- Trial name
- MisTher (NCT05653414)
- Testing
- short early psychological care associated with encouragement of early support consultation with generalist practitioner or midwife, encouragement of early support consultation with generalist practitioner or midwife
- Volunteers
- 932 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne
Grief, Post Traumatic Stress Disorder
Walk With Me (WWM) for Perinatal Grief
The goal of this clinical trial is to learn if the Along With Me web-based intervention works to decrease posttraumatic stress symptoms and suicidal ideation among bereaved parents following pregnancy and early infant loss.
- Conditions
- Grief, Post Traumatic Stress Disorder, Suicidal Ideation, Miscarriage
- Trial name
- PeriGrief-II (NCT07011940)
- Testing
- Along With Me, Peer Guide
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.