Clinical trials: Post-Traumatic Stress Symptoms
Substance-Related Disorders, Depression
Wraparound for High-risk Families with Substance Use Disorders: Examining Family, Child, and Parent Outcomes
The investigators propose a Hybrid Type 1 effectiveness-implementation quasi-experimental trial. Participants are drawn from two different communities contemporaneously.
- Conditions
- Substance-Related Disorders, Depression, Stress Disorders, Post-Traumatic, Child Abuse
- Trial name
- NCT04637581
- Testing
- Wraparound
- Where
- 4 sites in United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Depression, Post-traumatic Stress Disorder
Evaluating Implementation Strategies to Scale-up Transdiagnostic Evidence-based Mental Health Care in Zambia
This study utilizes a Hybrid Type 1 multi-arm parallel group randomized control design to compare the effectiveness of an evidence-based treatment (CETA) delivered either in-person or via telephone, compared with a treatment as…
- Conditions
- Depression, Post-traumatic Stress Disorder, Anxiety, Substance Abuse
- Trial name
- NCT03458039
- Testing
- In-person CETA, Telephone CETA, Treatment as Usual (TAU)
- Where
- Zambia
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Critical Illness, Stress
Effects of a Psycho-cognitive Nursing Intervention on Patients' Outcomes in Critical Illness
The purpose of this study is to investigate whether a psycho-cognitive nursing intervention including relaxation, guided imagery, touch and music listening can improve the clinical and psychological outcome of critically ill…
- Conditions
- Critical Illness, Stress, Inflammatory Response
- Trial name
- NCT02423252
- Testing
- Massage, Relaxation, Guided imagery and music listening., No Intervention
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr Elizabeth Papathanassoglou
Stress Disorders, Post-Traumatic, Depression
Resettled Refugee Families for Healing
The goal of this type I hybrid effectiveness-implementation trial is to test a family strengthening (FS) model delivered through multiple family groups (MFG) combined with a virtual peer mentoring program called TeenAge Health…
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Antisocial Personality Disorder, Anxiety
- Trial name
- RRF4H (NCT06176638)
- Testing
- RRF4H Combination Intervention
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Posttraumatic Stress Disorder (PTSD)
Trajectories of Psychopathology in Response to NET
Narrative Exposure Therapy (NET) has been proven to be effective in the treatment of Posttraumatic Stress Disorder (PTSD) and trauma-related depression in more than a dozen controlled clinical trials.
- Trial name
- TOP-NET (NCT02852616)
- Testing
- Narrative Exposure Therapy
- Where
- Germany
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Post Traumatic Stress Disorder, Depression
Impact of COVID-19 Pandemic in Perinatal Mental Health (RISEUP-PPD-COVID-19)
Introduction: Coronavirus disease 2019 (COVID-19) is a new pathology, declared a public health emergency by the World Health Organization, which can have negative consequences for pregnant women and their newborns.
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety, Psychological Distress
- Trial name
- NCT04595123
- Where
- 13 sites in Albania, Brazil and 11 more
- Volunteers
- 7,642 people, healthy volunteers welcome
- Sponsor
- University of Minho
Covid19, Mental Health Disorder
MIND/COVID-19: Mental Health Impact and NeeDs Associated With COVID-19: a Comprehensive National Evaluation in Spain
The aim of the proposed project is to provide a comprehensive assessment of the mental health impact of the ongoing COVID-19 outbreak in Spain.
- Conditions
- Covid19, Mental Health Disorder, Mental Health Conditions
- Trial name
- NCT04556565
- Where
- 18 sites in Spain
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Jordi Alonso
Stress, Anxiety
Stress Resilience Training System
The Stress Resilience Training System (SRTS) program is a stress reduction and resilience building system that blends cognitive training to anticipate the effects of stress with advanced biofeedback to mitigate stress effects and…
- Conditions
- Stress, Anxiety, Depression, PTSD
- Trial name
- SRTS (NCT01599624)
- Testing
- Stress Resilience Training System (SRTS), Progressive Muscle Relaxation (PMR)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Burnout, Professional, Self Compassion
Better Together Physician Coaching to Mitigate Burnout Amongst Clinicians
Better Together Physician Coaching ("Better Together", or "BT"), a 4-month, web-based positive psychology multimodal coaching program was built to decrease burnout in medical trainees.
- Conditions
- Burnout, Professional, Self Compassion, Flourishing, Imposter Syndrome
- Trial name
- NCT05635448
- Testing
- Better Together Physician Coaching Program, No intervention - waitlist control
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cancer of Ovary, Endometrium Cancer
The Effect of Logotherapy on Mental Health in Gynecological Cancer Patients
Gynecological cancers negatively affect women's sexuality, fertility, body image, and self-perception, resulting in deterioration in their psychological health.
- Conditions
- Cancer of Ovary, Endometrium Cancer, Cervix Cancer
- Trial name
- NCT05246462
- Testing
- Logotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Posttraumatic Stress Disorder (PTSD)
Inflammatory Challenge and Fear
The goal of this study is to learn if short-term changes in the immune system alter how we process information and experience fear.
- Trial name
- LIFE (NCT06630884)
- Testing
- Typhoid VI Polysaccharide Vaccine Injectable Solution
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Depression, Panic Disorder
Evaluating the Effects of Stress in Pregnancy
This study will evaluate pregnant women with a past or current diagnosis of depression or anxiety to gain a better understanding of how these disorders can affect an infant's development, both during and after pregnancy.
- Conditions
- Depression, Panic Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder
- Trial name
- NCT00525226
- Where
- United States
- Volunteers
- 1,431 people, healthy volunteers welcome
- Sponsor
- Emory University
PTSD, Sleep Disorders
Cooperative Studies Program #563 - Prazosin and Combat Trauma PTSD
Background: Posttraumatic stress disorder (PTSD) is a debilitating and disabling mental disorder that afflicts at least 25% of Veterans who have suffered life-threatening war zone trauma.
- Trial name
- PACT (NCT00532493)
- Testing
- prazosin
- Where
- 15 sites in United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Psychiatric Health
Complex Post-traumatic Stress Disorder: What Symptomatological Specificities
A better understanding of the Complex Post-Traumatic Stress Disorder would allow a management as close as possible to the specificities of this one, but also a better training of professionals and adapted therapeutic indications.
- Trial name
- StuCoTra (NCT05070962)
- Testing
- clinical population
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Raincy Montfermeil Hospital Group
Posttraumatic Stress Disorder
Using Attentional Bias Modification to Address Trauma Symptoms
Threat-related attentional biases have been identified as a possible precursor to the onset and maintenance of posttraumatic stress disorder (PTSD).
- Trial name
- NCT02615717
- Testing
- Attention Bias Modification
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Post Traumatic Stress Disorder, Smoking
Computerized Tailored Intervention for Behavioral Sequelae of PTSD in Veterans
This project assesses the usability and feasibility of a multi-behavioral computerized, tailored intervention (CTI) or expert system delivered via the Internet for veterans with Post-Traumatic Stress symptoms.
- Conditions
- Post Traumatic Stress Disorder, Smoking, Anxiety, Depression
- Trial name
- CTI-PTSD (NCT01510834)
- Testing
- Multibehavioral, Computerized Tailored Intervention STR2IVE
- Where
- 3 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- VA Pacific Islands Health Care System
Tinnitus, Traumatic Brain Injury
Investigating the Neurobiology of Tinnitus
The investigators hypothesize that individual differences exist in resting-state cortical attention, control, sensory, and emotion networks prior to noise exposure and these differences predispose some to the development of…
- Conditions
- Tinnitus, Traumatic Brain Injury, Post Traumatic Stress Disorder
- Trial name
- NCT01294124
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Moral Injury, Distress, Emotional
Digital Interventions for Detection and Reduction of Moral Distress
Stress, anxiety, distress and depression are exceptionally high among healthcare workers at the frontline of the COVID-19 pandemic.
- Trial name
- VR (NCT05001542)
- Testing
- Educational moral injury video
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Post Traumatic Stress Disorder
Effect of Eye Movement Desensitization and Reprocessing Therapy 2.0 Online Group Protocol
In this study, it will be investigated the efficacy of Eye Movement Desensitization and Reprocessing Therapy 2.0 Online Group Protocol on post-traumatic symptoms compared to control group.
- Trial name
- NCT05596903
- Testing
- EMDR 2.0 group protocol, Mhgap stress module
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Academy of Therapeutic Sciences, Turkey