Clinical trials: Post-cardiac Surgery Patients
Open Heart Surgery Patients
Quality of Life After Open Heart Surgery in Older Patients
Long term follow-up of nonagenarians who have undergone open heart procedures.
- Trial name
- NCT00248898
- Testing
- Cardiac Surgery
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Weill Medical College of Cornell University
Older Patients, Surgery
Long-term Follow-up of Dexmedetomidine-esketamine and tDCS for Neurocognitive Complications After Surgery
Neurocognitive complications, mainly delirium and neurocognitive disorders, are common cerebral complications in older patients after surgery and associated with worse long-term outcomes.
- Conditions
- Older Patients, Surgery, Dexmedetomidine, Esketamine
- Trial name
- NCT07576543
- Testing
- Dex-Esk, Active tDCS
- Where
- 6 sites in China
- Volunteers
- 1,996 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Coronary Artery Disease, Valvular Heart Disease
Efficacy of Sternum Guard in Post Cardiac Surgery Patient
This is a single-center, single-blind, randomized parallel superiority trial comparing two groups; Sternum GuardTM as the treatment arm and Bone Wax as the active control group.
- Conditions
- Coronary Artery Disease, Valvular Heart Disease, Congenital Heart Disease in Adolescence, Post Operative Wound Infection
- Trial name
- NCT05229276
- Testing
- Sternum Guard, Bone Wax
- Where
- Indonesia
- Volunteers
- 414 people
- Sponsor
- Universitas Indonesia
Post Operative Arrythmia
Impact of Ligament of Marshall Resection on Atrial Fibrillation Occurrence in Patients Undergoing Coronary Artery Bypass Grafting: A Randomized Controlled Trial
Background: 20-40% of patients with ischemic heart disease managed with coronary artery bypass grafting (CABG) surgeries face the risk of postoperative atrial fibrillation (POAF), which is a known hazardous outcome.
- Trial name
- NCT07492901
- Testing
- A standard on-pump coronary artery bypass grafting (ON-CAB), adjunctive LoM resection
- Where
- 2 sites in Egypt
- Volunteers
- 220 people
- Sponsor
- Kasr El Aini Hospital
Coronary Artery Bypass Graft Surgery, Mace
Discharge Planning Program for Post CABG Patients
The current study is utilizing a nurse led discharge program based on the Re-Engineered Discharge program (Project-RED) ( Agency of Healthcare Research and Quality [AHRQ], 2013) which is a package of services designed to minimize…
- Conditions
- Coronary Artery Bypass Graft Surgery, Mace, 30 Day Mortality
- Trial name
- NCT04527822
- Testing
- Nurse led discharge planning program
- Where
- Jordan
- Volunteers
- 174 people
- Sponsor
- University of Jordan
Aortic Dissection Type A, Acute Kidney Injury Cardiac Surgery
Preoperative Ankle-Brachial Index and Renal Adverse Events After Acute Type A Aortic Dissection Surgery
This single-centre retrospective observational cohort study evaluated the association between preoperative cuff-derived ankle-brachial index (ABI) and postoperative acute kidney injury (AKI) in adults undergoing emergency repair…
- Trial name
- NCT07668830
- Testing
- Preoperative Ankle-Brachial Index
- Where
- China
- Volunteers
- 516 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Open Heart Surgery, Tele-nursing
Tele-Nursing Follow-Up After Open Heart Surgery
Introduction: Failure to follow-up patients by healthcare professionals after discharge may increase the development of anxiety and complications in patients.
- Trial name
- NCT05316207
- Testing
- Telenursing
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Hasan Kalyoncu University
CABG
Alpha Ketoglutarate Enhances Geroprotection In Surgery (AEGIS)
One of the most common major surgeries that older patients undergo is coronary artery bypass grafting surgery (CABG), which is performed in approximately 400,000 patients in the United States each year.
- Trial name
- NCT07031128
- Testing
- Alpha-ketoglutarate
- Where
- 2 sites in Singapore
- Volunteers
- 250 people
- Sponsor
- National University Hospital, Singapore
Coronary Artery Bypass Graft Surgery(CABG), Postoperative Pain Management
VR During Chest Tube Removal After CABG
The purpose of this randomized controlled clinical trial was to investigate whether virtual reality (VR) could reduce pain and anxiety during chest tube removal in adult patients who underwent coronary artery bypass graft (CABG)…
- Trial name
- VR-CABG (NCT07891299)
- Testing
- VR Shinecon G04EA Virtual Reality Headset
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Maltepe University
Vascular Disease, Hypertension
Tight Hemodynamic Control in Patients Who Are Chronically on Metoprolol
This study proposes to assess the effect of the standard of care, which is continuation of the pre op beta blocker dose into the post operative period compared to the administration of esmolol titrated to a pre determined target…
- Conditions
- Vascular Disease, Hypertension, Angina, Cardiac Disease
- Trial name
- NCT01404767
- Testing
- Esmolol, Metoprolol
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Post Operative Atrial Fibrillation
The Impact of Oral Vitamin C in Prevention for Post Operative Atrial Fibrillation (POAF) in Coronary Artery Bypass Surgery (CABG) Patients
Post operative atrial fibrillation (POAF) is one of the most common complications that takes place worldwide after coronary artery bypass surgeries (CABG).
- Trial name
- NCT06074367
- Testing
- Vitamin C 500 MG Oral Capsule(High dose 2g daily), Vitamin C 500 MG Oral Capsule(Low-dose 1g daily)
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Helwan University
Hypotension on Induction, Frailty
EASIX Score and Post-Induction Hypotension in Frail Patients Undergoing Non-Cardiac Surgery
Post-induction hypotension (PIH) is a common and clinically significant hemodynamic complication following general anesthesia induction.
- Conditions
- Hypotension on Induction, Frailty, Anesthesia, General
- Trial name
- PIXEL (NCT07642765)
- Testing
- EASIX Score Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Konya City Hospital
Sternotomy, Cardiovascular Diseases
RCT on T-REX Twente Regimen Effects on Quality of Life and Mobilisation for Cardiac Surgery Patients After Sternotomy
The goal of this study is whether the T-REX Twente precautions have a positive impact on the quality of life (MAcNew QLMI), level of physical activity, and reduction of fear of movement in heart patients after a total median…
- Conditions
- Sternotomy, Cardiovascular Diseases, Physical Inactivity, Quality of Life
- Trial name
- T-REX Twente (NCT06115759)
- Testing
- T-REX Twente precautions, Usual (restrictive) sternal precautions
- Where
- Netherlands
- Volunteers
- 154 people
- Sponsor
- Medisch Spectrum Twente
Postoperative Nausea and Vomiting
Prophylactic Ondansetron in Post-op Cardiac Surgery Patients to Prevent Post-operative Nausea and Vomiting
To evaluate the effectiveness of a prophylactic dose of ondansetron in decreasing the incidence of post-operative nausea and vomiting in cardiac surgery patients after cessation of post-operative sedation.
- Trial name
- NCT02966041
- Testing
- Ondansetron, Saline
- Where
- Canada
- Volunteers
- 186 people
- Sponsor
- University of British Columbia
Postoperative Cognitive Dysfunction (POCD), Cardiac Surgery
PCO₂ Gap and Lactate as Predictors of POCD After Cardiac Surgery
This prospective observational study aims to evaluate whether intraoperative venous-to-arterial carbon dioxide partial pressure difference (PCO₂ gap) and arterial lactate levels can serve as early predictors of postoperative…
- Conditions
- Postoperative Cognitive Dysfunction (POCD), Cardiac Surgery, Cardiopulmonary Bypass
- Trial name
- NCT07843186
- Volunteers
- 185 people
- Sponsor
- Ain Shams University
Right Ventricular Function, Prone Position
Bedside Assessment of Right Ventricular Output Lying in Prone Or Supine
Right ventricular failure (RVF) is a common complication to cardiac surgery, which is associated to mortality, kidney failure, stroke, prolonged mechanical ventilation and ICU stay.
- Conditions
- Right Ventricular Function, Prone Position, Atelectasis, Atelectases, Postoperative Pulmonary
- Trial name
- BAROLO (NCT07632027)
- Testing
- Prone position
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Sahlgrenska University Hospital
Microcirculatory Diffusion, Microcirculatory Convection Capacity
Association of Microcirculation, Vexus Score and Femoral Vein Doppler in Patients on the ICU After Non-emergency Cardiac Surgery
The aim of the VeMic study is to explore if venous congestion is linked with microcirculatory impairment in elective cardiac surgery patients in the postoperative ICU stay.
- Conditions
- Microcirculatory Diffusion, Microcirculatory Convection Capacity, Venous Congestion, Postoperative Cardiac Surgery
- Trial name
- VeMic (NCT07052461)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University Hospital, Basel, Switzerland
Delirium
Incidence, Severity and Treatment of Delirium in Cardiac Surgery Patients: A Before-after Study
Delirium is a common yet under diagnosed condition in hospitalized patients, and the incidence have not previously been described in Danish cardiac surgery patients.
- Trial name
- NCT01774240
- Testing
- systematic screening and treatment of delirium
- Where
- Denmark
- Volunteers
- 230 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Atrial Fibrillation, Acute Kidney Injury
Autonomic State, Cardiovascular Control and Outcomes in Coronary Surgery
Characterization of the perioperative autonomic nervous system state, cardiovascular and cerebrovascular control and microcirculation in order to predict postoperative atrial fibrillation and acute kidney injury in patients…
- Trial name
- NCT03169608
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Policlinico S. Donato
Incentive Spirometry, Oxygen Saturation
The Effects Incentive Spirometry Use in Coronary Artery Bypass Surgery
Background: Incentive spirometry is used in addition to care, especially in reducing pulmonary complications after surgery. Complications in the cardiovascular and pulmonary systems can basically be determined by blood values and…
- Trial name
- NCT05192785
- Testing
- Incentive Spirometry Group
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cukurova University