Clinical trials: Post-cardiac Surgery Patients
Postoperative Pain, Cardiac Surgery
Comparison of Paravertebral Block and Deep Parasternal Intercostal Plane Block in Cardiac Surgery
Median sternotomy is commonly used in cardiac surgery and is often associated with significant postoperative pain. Poor pain control after sternotomy may increase opioid use, delay mobilization, prolong extubation time, and…
- Conditions
- Postoperative Pain, Cardiac Surgery, Postoperative Pain After Cardiac Surgery Via Median Sternotomy
- Trial name
- SPARE-CABG (NCT07498946)
- Testing
- Thoracic paravertebral block (TPVB), Bilateral Deep Parasternal Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gaziantep City Hospital
Heart; Surgery, Heart, Functional Disturbance as Result
Multifunctional Approach in Cardiac Surgery
Postoperative pain and swallowing disorders are complex, multifactorial phenomenon that frequently occur after cardiac surgery. Preoperative anxiety and the interaction between sex and other sociocultural factors may predict…
- Trial name
- TITANIC (NCT05824598)
- Testing
- Multifunctional rehabilitation treatment
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Surgical Site Infection, Coronary Artery Bypass Grafting (CABG)
Effect of Nurse-Led Education and Tele-Interventions on Reducing Surgical Site Infections in Patients After Coronary Artery Bypass Surgery: a Clinical Trial
The goal of this clinical trial is to determine if nurse-led education and tele-interventions can reduce the incidence of surgical wound infections in patients after coronary artery bypass surgery.
- Trial name
- NCT06586749
- Testing
- Group B: nurse-led education, Group C: nurse-led education and implementation of teleinterventions
- Where
- Greece
- Volunteers
- 220 people
- Sponsor
- Hellenic Mediterranean University
Post Operative Atrial Fibrillation
Post Operative Atrial Fibrillation Post Cardiac Surgery ( CABG and VALVE REPLACEMENT )
This study aims to assess the percent and risk factors of postoperative atrial fibrillation in patients undergoing cardiac surgery in Assiut university heart hospital
- Trial name
- NCT06763120
- Where
- Egypt
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Assiut University
Patient Blood Management, Cardiac Surgery
Study on the Relationship of Arterial-venous Oxygen Difference and Postoperative Complications After Cardiac Surgery.
Avoidance of unnecessary blood transfusions has always been a focus of clinical research. The rate of perioperative red blood cell transfusion in patients undergoing cardiac surgery under cardiopulmonary bypass reaches between…
- Conditions
- Patient Blood Management, Cardiac Surgery, Transfusion
- Trial name
- NCT05078086
- Testing
- No intervention
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Atrioventricular Block, Cardiac Surgery
OPTImizing Lead Placement in Patients Requiring Pacemaker After Cardiac Surgery
Conventional right ventricular pacing has been associated with ventricular dyssynchrony and an increased risk of pacing-induced cardiomyopathy, which may lead to worse clinical outcomes.
- Trial name
- OPTI-PACS (NCT07795541)
- Testing
- Left bundle branch area pacing, Conventional pacing strategy
- Volunteers
- 110 people
- Sponsor
- Sahlgrenska University Hospital
Coronary Artery Disease, Postoperative Cognitive Dysfunction
Cerebral Oximetry and Neurocognitive Functions in Cardiosurgical Patients
It is previously reported that the cerebral oxygen desaturation during cardiac surgery is associated with an increased incidence of cognitive impairment.
- Conditions
- Coronary Artery Disease, Postoperative Cognitive Dysfunction, Neurological Impairment
- Trial name
- NCT00917124
- Testing
- INVOS
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- University of Zagreb
Pulmonary Regurgitation, Tetralogy of Fallot
Multi-center Trial of Percutaneous Pulmonary Valve Implantation With Venus-p
Venus-P Valve (Venus Medtech, Shanghai, China) is the first self-expandable interventional Pulmonary Valve, which is composed of a Nitinol multilevel support frame with a tri-leaflet porcine pericardial tissue valve, and a 14-22…
- Trial name
- Venus-P (NCT02590679)
- Testing
- Venues-P Valve
- Where
- 3 sites in China
- Volunteers
- 44 people
- Sponsor
- Shanghai Zhongshan Hospital
Minimally Invasive Cardiac Surgery
The Quality of Life and Patency Rate After Minimally Invasive Cardiac Surgery
This trial will address essential questions of the efficacy and safety of MICS-CABG in addition to the quality of life and patency rate of the grafts.
- Trial name
- NCT05104320
- Testing
- MICS-CABG, sternotomy CABG
- Volunteers
- 248 people
- Sponsor
- Peking University Third Hospital
Coronary Artery Disease, Sleep Quality
Effect of Eye Mask Use on Sleep Quality and Delirium After CABG Surgery
Coronary artery bypass graft (CABG) surgery is an effective treatment for coronary artery disease; however, sleep disturbances and delirium are common during the postoperative period and may adversely affect recovery.
- Conditions
- Coronary Artery Disease, Sleep Quality, Postoperative Delirium (POD)
- Trial name
- EYE-CABG (NCT07768020)
- Testing
- Eye Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Munzur University
Post-discharge Outcomes
Retrospective Observational Study of Patients Who Have Undergone Coronary Artery Bypass Graft (CABG) and/or Cardiac Valve Surgery
This study is a retrospective chart abstraction for subjects who were enrolled in REN-004. As a retrospective study, all data will be abstracted from the medical records.
- Trial name
- NCT07009340
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Renibus Therapeutics, Inc.
Coronary Artery Disease, Pain Syndrome
Effect of Bilateral Transversus Thoracis Muscle Plane Block in Patients Undergoing Coronary Artery Bypass Graft Surgery.
Coronary artery bypass graft surgery is the standard surgical treatment for coronary disease. However, there is no consensus on analgesic management in patients undergoing CABG.
- Trial name
- PARACABS (NCT04849117)
- Testing
- Ultrasound guided Bilateral Transversus Thoracis Muscle Plane block
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Pulmonary Complications
Effectiveness Of Modified Chest PT Technidue In Pre And Post-Operative Program In Patients Open Heart Surgery
The purpose of this study is to explore effectiveness of modified chest physical therapy techniques using new device in pre and post-operative program in patients undergoing open heart surgery
- Trial name
- NCT02894879
- Testing
- BreatheMAX®, Routine treatment
- Where
- Thailand
- Volunteers
- 48 people
- Sponsor
- Khon Kaen University
Coronary Artery Disease
Using WHOOP Fitness Band to Measure Heart Health Variability Before and After Surgery
The goal of this observational study is to use the WHOOP device to measure heart rate variability (HRV) in patients with coronary artery disease (CAD) before and after they have CABG (coronary artery bypass graft) surgery.
- Trial name
- NCT07097168
- Where
- United States
- Sponsor
- Tufts Medical Center
Hyperoxia, Normoxic
Intraoperative Oxygen Concentration and Neurocognition After Cardiac Surgery
This is a randomized, prospective controlled trial in patients undergoing cardiac surgery, specifically on-pump coronary artery bypass grafting, comparing level of administered oxygen and partial pressure of arterial oxygen in…
- Conditions
- Hyperoxia, Normoxic, Delirium
- Trial name
- NCT02591589
- Testing
- Normoxic oxygenation, Hyperoxic oxygenation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Beth Israel Deaconess Medical Center
Intensive Care Unit
Effect of Ketamine Assisted Analgesia on Oxygen Supply and Oxygen Consumption in Patients After Cardiac Surgery
After cardiopulmonary bypass heart surgery, with the rewarming of body temperature, the metabolic capacity of the body is enhanced, the microcirculation is opened, and tissue perfusion is increased.
- Trial name
- NCT04906915
- Testing
- Ketamine
- Where
- China
- Volunteers
- 112 people
- Sponsor
- First People's Hospital of Chenzhou
Neutrophil Lymphocyte Ratio, Serum Createnine
Does Preconditioning Affects Other Organs in Patients Undergoing Open Heart Surgery ?
An association between white blood cell count (WBC), neutrophil-lymphocyte ratio , and inflammatory process is well known . Ischemic preconditioning reduces the inflammation
- Conditions
- Neutrophil Lymphocyte Ratio, Serum Createnine, Mechanical Ventilation
- Trial name
- NCT03097692
- Testing
- ischemic preconditioning, Pharmacologic preconditionig
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cardiac Surgery, Post-operative Pain
Reduce Nonsteroidal Antiinflammatory Drugs Doses for Analgesia After Sternotomy
Currently, the management of pain after cardiac surgery is based on the concept of multimodal analgesia: Combined use of non-opioid analgesics associated with morphine intravenous analgesia by a system controlled by the patient…
- Trial name
- LoDoNSAID (NCT02180087)
- Testing
- Ketoprofen
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Mechanical Ventilation Complication, Congenital Heart Disease
Application of Neurally Adjusted Ventilatory Assist to Children After Congenital Cardiac Surgery
Neurally adjusted ventilatory assist (NAVA) is a new mode of mechanical ventilation that delivers ventilatory assist in proportion to neural effort.
- Trial name
- NCT01662011
- Testing
- mode of neurally adjusted ventilatory assist, Mode of pressure support ventilation
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Coronary Artery Bypass
Enhancing Care Study in Patients After CABG
Review the data of patients who underwent coronary artery bypass grafting (CABG) at the National Center for Cardiovascular Disease, Fuwai Hospital from January 2013 to June 2023 including medical history, head CT scan, and…
- Trial name
- OptiCABG (NCT06488352)
- Where
- China
- Volunteers
- 40,000 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital