Clinical trials: Post-dural Puncture Headache
Post-Dural Puncture Headache, Chronic Headache
Long-term Complications of Unintentional Dural Puncture During Labour Epidurals and Epidural Blood Patch.
The investigators plan to evaluate long-term consequences of unintentional dural puncture in women who had this complication during labor epidural insertion at Mount Sinai Hospital.
- Trial name
- NCT04696627
- Testing
- Questionnaire
- Where
- Canada
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Post-dural Puncture Headache, Post-dural Puncture Backache
Long-term Effects of Accidental Dural Puncture in Patients Having Had an Epidural Blood Patch (LEAP)
Accidental dural puncture (ADP) during placement of an epidural catheter for anesthesia and analgesia is a well known complication. Previous studies have found audiometric deterioration following ADP.
- Trial name
- LEAP (NCT02149680)
- Where
- 2 sites in Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Spinal and Epidural Anaesthesia-Induced Headache During Pregnancy
Establishment of a Predictive Model for Post-dural Puncture Headache
The goal of this clinical trial is to establish a predictive model for post-dural puncture headache. The main questions it aims to answer are: Changes in intracranial pressure after spinal puncture (or lumbar puncture).
- Trial name
- NCT06800859
- Testing
- Supplement fluids
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Yilin Zhao
Cesarean Section Complications
Ultrasonographic ONSD as a Predictor of PDPH in Spinal Anesthesia for Cesarean Delivery
The Optic Nerve Sheath Diameter (ONSD), measured non-invasively by bedside ultrasound, is a well-established surrogate for intracranial pressure (ICP), as the optic nerve sheath is continuous with the intracranial dura mater and…
- Trial name
- NCT07360756
- Testing
- Study Cohort (Single Cohort)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Al-Azhar University
Post-dural Puncture Headache
Post-dural Puncture Headache - Needles and Biomarkers in CSF
Post-dural puncture headache (PDPH) is the most common complication following lumbar puncture (LP). The frequency varies widely depending on a number of factors, among which patient characteristics, case ascertainment, gauge and…
- Trial name
- NCT02384031
- Testing
- Traumatic needle, Atraumatic needle
- Where
- Norway
- Volunteers
- 172 people
- Sponsor
- Nordlandssykehuset HF
Post-Dural Puncture Headache
Neostigmine and Glycopyrrolate for the Treatment of Headache After Dural Puncture
The purpose of this study is to evaluate Neostigmine and Glycopyrrolate to treat post-dural puncture headache (PDPH) to reduce the proportion of postpartum women with a PDPH requiring epidural blood patch (EBP) who developed a…
- Trial name
- NCT05116930
- Testing
- Neostigmine, Glycopyrrolate
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Mayo Clinic
Plasma Rich Fibrin, Epidural
Plasma Rich Fibrin Epidural Injection by Racz Catheter in Postdural Puncture Headache Guided Optic Nerve Sheath Diameter
This study aims to evaluate plasma-rich fibrin epidural injection by Racz catheter in post-dural puncture headaches guided optic nerve sheath diameter.
- Conditions
- Plasma Rich Fibrin, Epidural, Racz Catheter, Postdural Puncture Headache
- Trial name
- NCT06790758
- Testing
- Plasma rich fibrin epidural injection by Racz catheter
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Parturient Who Underwent Epidural Anesthesia During Which an Unintentional Dural Punctur Occurred, Parturient Who Develop a Postdural Puncture Headache
Chronic Headache and Chronic Backache Following Unintentional Dural Puncture at Delivery Room.
he study is a telephone questionnaire. The study will include 400 women, 100 in each group. OBJECTIVE: To investigate the prevalence of chronic and chronic back pain following PDPH accidental dural puncture during epidyral…
- Conditions
- Parturient Who Underwent Epidural Anesthesia During Which an Unintentional Dural Punctur Occurred, Parturient Who Develop a Postdural Puncture Headache, Parturient Who Gave Informed Consent to Participation in the Study
- Trial name
- NCT03908424
- Testing
- Epidural Blood patch.
- Where
- Israel
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Leukemia, Lymphoma
Self-control Trial to Evaluate the Role of Aprepitant in the Prophylaxis of Post-lumbar-punture-headache (PLPH)
Headache following a lumbar puncture （post-lumbar-puncture headache,PLPH）is a common and often debilitating syndrome, which was reported to occur in about 40% patients who received lumbar puncture.
- Trial name
- NCT02347878
- Testing
- Aprepitant
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Sun Yat-sen University
Postdural Puncture Headache, Postoperative Nausea and Vomiting
Ondansetron and Dexamethasone for Prevention of PDPH, Nausea, and Vomiting
This prospective, randomized, double-blind, placebo-controlled study was conducted at the Obstetrics and Gynecology Department of El-Minia University Hospital from October 2018 to October 2019.
- Conditions
- Postdural Puncture Headache, Postoperative Nausea and Vomiting, Obstetric Anesthesia Problems
- Trial name
- PDPH-N/V (NCT07068230)
- Testing
- Ondansetron 8mg, Dexamethasone, Saline
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
Postdural Puncture Headache
Addition of Pyridostigmine to Conventional Management of Postdural Puncture Headache
Postdural puncture headache (PDPH) is a major complication of neuraxial anesthesia that can occur following spinal anesthesia and with inadvertent Dural puncture during epidural anesthesia.
- Trial name
- NCT05969119
- Testing
- Pyridostigmine
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postdural Puncture Headache
Effect of Coffee on Postdural Puncture Headache After Cesarean Section
The purpose of this study is to investigate the effects of postoperative coffee consumption on postdural puncture headache (PDPH) and analgesic use in women undergoing cesarean section with spinal anesthesia.
- Trial name
- NCT07410741
- Testing
- Coffee Consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
PDPH
Prophylactic Intrathecal Normal Saline for Prevention of Post Dural Puncture Headache in Women Undergoing Cesarean Section Under Spinal Anesthesia
The rates of cesarean section are increasing worldwide despite ten to fifteen percent of World Health Organization recommendation and from which 80-90% of cesarean sections are performed with spinal anesthesia.
- Trial name
- PDPH (NCT04393766)
- Testing
- Normal Saline
- Where
- Ethiopia
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Dilla University
Blood Patch, Post-Dural Puncture Headache
Factors Associated With the Onset of Chronic Headaches in Patients Who Received a Blood Patch in Post Partum
The purpose of this study is to identify possible links between conditions for carrying out a blood patch (BP) to treat accidental post dural puncture acute headache (PDPH) in the early post partum period and occurrence of…
- Trial name
- CHROBLOOD (NCT05888324)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post Dural Puncture Headache
"Isometric Lower Limbs Exercises Affect on Cardiac Parameters and Headache in Patient After Spinal Anesthesia"
the Objectives of this clinical trial is : 1. Examine the effect of lower limbs isometric muscle exercises on cardiac parameters in patients after spinal anesthesia. 2.
- Trial name
- LILE-SPA (NCT07547150)
- Testing
- Lower Limb Isometric Exercise
- Where
- Iraq
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Karbala University
Tissue Oxygenation
Postspinal Headache and Near Infrared Spectroscopy (NIRS)
Evaluation of the relationship between postspinal headache and near infrared spectroscopy in cesarean section patients
- Trial name
- NCT04187846
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Hakan Tapar
Hypotension in Pregnant Women, Headache in Pregnant Women
Prediction of Hypotension and Postdural Puncture Headache by Carotid Artery Corrected Flow Time
Anesthesia for cesarean delivery can be provided through general or neuraxial anesthesia (spinal or epidural). Hypotension is a common complication of both methods.
- Trial name
- NCT07372313
- Volunteers
- 90 people
- Sponsor
- TC Erciyes University
Spontaneous Intracranial Hypotension, Intracranial Hypotension
Pathophysiology and Treatment of Cerebrospinal Hypotension Exploration Study
The goal of this observational study is to learn about the effects of a low-pressure environment on the brain in patients with intracranial hypotension and to potentially improve diagnostics and treatment of this condition.
- Conditions
- Spontaneous Intracranial Hypotension, Intracranial Hypotension, Post-Lumbar Puncture Headache
- Trial name
- PATCHES (NCT06805591)
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Obstetric Anesthesia Problems, Headache
Post-dural Puncture Headache: A Retrospective Study
Neuraxial techniques are widely used in obstetric practice to provide analgesia and anesthesia. A common complication associated with neuraxial anesthesia is post-dural puncture headache (PDPH), resulting from unintentional or…
- Conditions
- Obstetric Anesthesia Problems, Headache, Epidural; Anesthesia, Headache
- Trial name
- NCT03790124
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Augusta University
Post-Dural Puncture Headache
Is Aminophylline More Effective Than Neostigmine/Atropine Mixture in the Treatment of Post-dural Puncture Headache
Objectives: To compare the safety and efficacy of IV aminophylline versus IV neostigmine/atropine mixture in the treatment of post-dural puncture headache (PDPH).
- Trial name
- RCT (NCT03997006)
- Testing
- IV Aminophylline, IV Neostigmine Methylsulfate + Atropine Sulphate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital