Clinical trials: Post-lumbar Puncture Headache
Post-Dural Puncture Headache
SGB in Management of Patients With PDPH Using TCD
This study aims to investigate the ability of SPGB in the management of PDPH. Transcranial Doppler is also used as an measure to assess the block success by detecting the variability in the cerebral hemodynamics before and after…
- Trial name
- NCT04401878
- Testing
- Sphenopalatine Ganglion Block using 2% lidocaine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Zagazig University
Post Dural Puncture Headache
Post Dural Puncture Headache After Accidental Dural Puncture
Epidural anesthesia is associated with potential risks and complications, post dural puncture headache (PDPH) one of the most recognized with epidural or spinal anesthesia.
- Trial name
- NCT01448590
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Headache
Juvenile Postlumbar Puncture Headache After Puncture With Needles With Quincke Tip or With Sprotte Tip
The purpose of this study is to compare postlumbar puncture complaints as headache or backache after lumbar puncture with needles with Quincke design or with Sprotte design in children and adolescents.
- Trial name
- NCT00450060
- Testing
- lumbar puncture with Quincke-design needles, lumbar puncture with Sprotte-design needles
- Where
- 2 sites in Germany
- Volunteers
- 150 people
- Sponsor
- Heidelberg University
Post-Dural Puncture Headache
The Occurrence of Post Dural Puncture Headache After Epidural Blood Patch
Spinal anesthesia is commonly used for cesarean section.However, the procedure is still have some adverse events such as high spinal block, nerve injuries or postdural puncture headache (PDPH).This is a potential complication of…
- Trial name
- NCT03080610
- Where
- 2 sites in Thailand
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Postdural Puncture Headache
2 Dose Neuraxial Morphine for Prevention of PDPH
Neuraxial analgesia (most commonly continuous epidural or combined spinal epidural) is the most effective modality available for pain relief during labor.
- Trial name
- NCT02473276
- Testing
- Morphine, Sterile normal saline
- Where
- 4 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Columbia University
Post-Dural Puncture Headache
Is Aminophylline More Effective Than Neostigmine/Atropine Mixture in the Treatment of Post-dural Puncture Headache
Objectives: To compare the safety and efficacy of IV aminophylline versus IV neostigmine/atropine mixture in the treatment of post-dural puncture headache (PDPH).
- Trial name
- RCT (NCT03997006)
- Testing
- IV Aminophylline, IV Neostigmine Methylsulfate + Atropine Sulphate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
Post-Lumbar Puncture Headache
Epidural Blood Patch on the Resolution of Postdural Puncture Headache (PDPH)
The purpose of this study is to address the question, "What is the volume of blood for injection at epidural blood patch that most effectively relieves post-dural puncture headache?"
- Trial name
- NCT00373074
- Testing
- Epidural Blood Patch
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Postdural Puncture Headache, Post-Lumbar Puncture Headache
Incidence of Headache Following an Unintentional Dural Puncture
The purpose of this study is to evaluate the use of intrathecal morphine administration following an unintentional dural puncture, to decrease the incidence of post dural puncture headaches (PDPH) in obstetric patients.
- Conditions
- Postdural Puncture Headache, Post-Lumbar Puncture Headache, Cerebrospinal Fluid Leaks
- Trial name
- NCT01977898
- Testing
- Morphine, Saline
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Headache, Post-Dural Puncture
Sphenopalatine Blockade Versus Clinical Treatment
Post-dural puncture headache leads to high morbidity and cost to the health system. Pregnant women have a higher incidence than other population groups.
- Trial name
- NCT04148846
- Testing
- Dypirone, Sphenopalatine block, Ketoprofen
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Sao Paulo General Hospital
Post-Dural Puncture Headache
Sphenopalatine Block Versus Greater Occipital Nerve Block in PDPH
Management of postdural puncture headache (PDPH) has always been challenging for anesthesiologists. PDPH not only increases the misery of the patient, but the length of stay and overall cost of treatment in the hospital also…
- Trial name
- NCT05235256
- Testing
- bilateral sphenopalatine ganglion block, bilateral greater occipital nerve block, lidocaine plus dexamethasone
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Post-Dural Puncture Headache, Chronic Headache
Long-term Complications of Unintentional Dural Puncture During Labour Epidurals and Epidural Blood Patch.
The investigators plan to evaluate long-term consequences of unintentional dural puncture in women who had this complication during labor epidural insertion at Mount Sinai Hospital.
- Trial name
- NCT04696627
- Testing
- Questionnaire
- Where
- Canada
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pregnancy, Headache After Spinal Puncture
Prediction of Postdural Puncture Headache
The primary objective of this study is to evaluate the effectiveness of inflammation index (pan-immune inflammation value, systemic immune inflammation index, and systemic inflammatory response index) values, calculated from…
- Trial name
- NCT07706751
- Where
- Turkey (Türkiye)
- Volunteers
- 260 people
- Sponsor
- Amasya University
Tecar Therapy Efficacy in the Treatment of PDPH
Radiofrequency Therapy of the Neck Muscles for Treating the Post-dural Puncture Headache After Cesarean Delivery.
Postdural puncture headache (PDPH) is a frequent complication after neuraxial anaesthesia due to accidental puncture of the dura mater. After spinal anaesthesia, the rate of PDPH may reach up to 28,7% of cases.
- Trial name
- NCT05695677
- Testing
- Capacitive-Resistive Radiofrequency therapy of the neck muscles
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Post-Dural Puncture Headache
RCT of SPG Blocks for Post-dural Headache
The purpose of the study is to assess the effectiveness of the SPG block with lidocaine vs. SPG block with placebo on preventing the need for EBP in women who develop PDPH after accidental dural puncture during placement of LEA…
- Trial name
- NCT03560349
- Testing
- Lidocaine HCl Gel 2%
- Where
- United States
- Sponsor
- University of Utah
Analgesia, Obstetrical, Post-Dural Puncture Headache
Intrathecal Catheter Placement Versus Resiting Epidural Catheter After Dural Puncture in Obstetric Patients
Epidural anesthesia represents the most popular method for pain relief during labour. Unintentional dural puncture (UDP) occurs in 0.4-1.5% of labour epidural analgesia, representing therefore the most common complication.
- Trial name
- ItaREVI (NCT05977361)
- Testing
- Resiting Epidural Catheter, Intrathecal Catheter Placement
- Volunteers
- 181 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Post-dural Puncture Headache
Evaluation of the Effectiveness and Tolerance of Tetracosactide Synacthen® in the Treatment of Post Dural Puncture Headaches (ESYBRECHE)
The aim of the study is to assess the efficacy and safety of Synacthène® versus placebo in the treatment of post-dural puncture syndrome in patients receiving epidural analgesia, spinal analgesia, or combined spinal-epidural…
- Trial name
- ESYBRECHE (NCT02813655)
- Testing
- Tetracosactide (Synacthène®)
- Where
- 2 sites in France
- Volunteers
- 46 people
- Sponsor
- Hospices Civils de Lyon
Post-Lumbar Puncture Headache
Headache After Diagnostic Lumbar Puncture
The objectives of this study are to investigate the effects of needle design, needle size and stylet reinsertion on the risk for headache after diagnostic LP (lumbar puncture, Post-LP headache).
- Trial name
- HELPUmeå (NCT03960749)
- Testing
- Sprotte 25G needle, stylet reinserted, Sprotte 25G needle, stylet not reinserted, Sprotte 22G needle, stylet reinserted
- Volunteers
- 1,000 people
- Sponsor
- Jonatan Salzer
Hypotension After Neuraxial Anesthesia, Cesarean Section
Comparing Spinal, Epidural, and Dural Puncture Epidural Anesthesia for Cesarean Delivery: Hemodynamics and Block Quality
The goal of this clinical trial is to compare three regional anesthesia techniques (spinal, epidural, and dural puncture epidural anesthesia) in healthy pregnant women undergoing planned (elective) cesarean delivery.
- Conditions
- Hypotension After Neuraxial Anesthesia, Cesarean Section, Anesthesia, Obstetrical, Post-Dural Puncture Headache
- Trial name
- NCT07883733
- Testing
- Spinal Anesthesia, Epidural Anesthesia, Dural Puncture Epidural Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Hearing Loss; Post-Dural Puncture Headache; Cesarean Delivery
Evaluation of Postoperative Hearing Loss After Spinal Anesthesia for Elective Cesarean Section in Pregnant Women
This prospective observational study will evaluate postoperative hearing changes in women undergoing elective cesarean delivery under spinal anesthesia.
- Trial name
- NCT07697651
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Duzce University
Plasma Rich Fibrin, Epidural
Plasma Rich Fibrin Epidural Injection by Racz Catheter Versus Epidural Blood Patch in Postdural Puncture Headache
This study aims to evaluate plasma-rich fibrin epidural injection by Racz catheter and epidural blood patch in Post dural puncture headache.
- Conditions
- Plasma Rich Fibrin, Epidural, Racz Catheter, Epidural Blood Patch
- Trial name
- NCT06790745
- Testing
- Epidural blood patch, Plasma rich fibrin epidural injection by Racz catheter
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University