Clinical trials: Post-menopause
Healthy, Menopause
Nitrate, Exercise and Vascular Function in Midlife Women
The purpose of this clinical study in women after menopause is to investigate whether the daily intake of nitrate from beetroot juice over 12 weeks enhances the positive effect of exercise training on vascular function, blood…
- Conditions
- Healthy, Menopause, Hypertension, Inflammation
- Trial name
- Women's-Beet (NCT06527248)
- Testing
- Nitrate group
- Where
- Austria
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Joint Discomfort, Joint Pain, Stiffness, Function
JDS-HF3.0 Supplementation on Menopause Related Quality of Life Outcomes in Postmenopausal Women
The goal of this interventional study is to evaluate whether the study product can help improve quality of life and reduce common menopause symptoms-such as joint discomfort, hot flashes and night sweats-in women aged 50-70.
- Conditions
- Joint Discomfort, Joint Pain, Stiffness, Function, Joint Pain, Hot Flashes
- Trial name
- NCT07238478
- Testing
- JDS-HF3.0
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Bonafide Health
Vaginal Atrophy, Genitourinary Syndrome of Menopause
The Efficacy of Topical Vaginal Oxytocin Gel in Postmenopausal Women With Vulvovaginal Atrophy
A Phase three randomized, double-blinded, study to asses the efficacy and safety of oxytocin gel in postmenopausal women with vaginal atrophy due to Genitourinary Syndrome of Menopause GSM.
- Conditions
- Vaginal Atrophy, Genitourinary Syndrome of Menopause, Vulvar Atrophy
- Trial name
- NCT06514586
- Testing
- Oxytocin, Hydroxypropyl methylcellulose
- Where
- Egypt
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Oxagon
Psychological Phenomena and Processes, Nutrition Physiological Phenomena
The Effects of Fiber on Appetite and Digestion Hormones
In this research study, investigators are interested in how certain dietary fibers in the diet affect certain hormones released from your intestine after eating and how these influence your appetite.
- Trial name
- FS (NCT01050101)
- Testing
- No fiber, Low GI high fiber viscous meal, Low GI high fiber non-viscous
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Gynecology
An Endometrial Cancer Chemoprevention Study of Metformin
The goal of this clinical research study is to learn about the effects of metformin and/or a program called "lifestyle intervention" on the endometrium (inner lining of the uterus) in post-menopausal women who are also obese…
- Trial name
- NCT01697566
- Testing
- Metformin, Endometrial Biopsy, Lifestyle Intervention
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Metabolic Health, Mental Health
Health Benefits of Dance Exercise
In Greece, people of different age groups, including young children to older adults, participate in dance exercise training. Although it is well-known that regular participation in dancing is associated with benefits such as…
- Conditions
- Metabolic Health, Mental Health, Physical Performance
- Trial name
- NCT07615829
- Testing
- Exercise training, No exercise training
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Vasomotor Symptoms (VMS) Associated With Menopause
An Observational Study to Learn More About Vasomotor Symptoms Burden and Treatment Patterns in Menopausal Women Before and After Participating in OASIS Studies
This is an observational study to learn more about vasomotor symptoms (VSM) burden and treatment patterns in menopausal women before and after participating in OASIS studies.
- Trial name
- OASIS STAR (NCT06949553)
- Testing
- No study intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
Osteoporosis, Postmenopausal Bone Loss
Mediterranean Diet for Post-menopausal Women: Effects on Bone Turnover
The investigators propose a 24 week clinical research trial (12 week observational period followed by 12 week MedSD intervention) with feasibility of diet adoption and markers of bone turnover as the primary outcomes.
- Trial name
- MedSD (NCT01653275)
- Testing
- Mediterranean Diet
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- UConn Health
Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness
To Assess Signs and Symptoms in Women Affected by GSM After One Cycle of Pixel CO2-Alma Fractionated Laser
Genitourinary syndrome of menopause (GSM) occurs in approximately 50% of menopausal women but is both underrecognized and undertreated despite numerous treatment options.
- Conditions
- Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness, Burning, Pain
- Trial name
- NCT05156502
- Testing
- Fractionated Laser (Pixel CO2-Alma), Fractionated Laser (Pixel CO.2-Alma)
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr. Filippo Murina
Healthy
Evaluation of the Pharmacokinetics, Safety, and Tolerability of IM Letrozole LEBE in Healthy Post-menopausal Women
This is a Phase I, open label, sequential, single ascending dose (SAD) study to evaluate the pharmacokinetic (PK), safety, and tolerability of Letrozole LEBE in healthy post-menopausal women.
- Trial name
- LEILA-1 (NCT06315205)
- Testing
- Letrozole LEBE 75 mg, Letrozole LEBE 150 mg, Letrozole LEBE 225 mg
- Where
- Czechia
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Rovi Pharmaceuticals Laboratories
Atherosclerosis, Postmenopause
EPAT: Estrogen in the Prevention of Atherosclerosis Trial
The purpose of this study is to determine the effects of estrogen replacement therapy (ERT) on the progression of early atherosclerosis in healthy postmenopausal women without preexisting cardiovascular disease (CVD).
- Trial name
- NCT00115024
- Testing
- Micronized 17B-estradiol
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Metabolic Syndrome, Postmenopausal Symptoms
Circadian Rhythms in Postmenopausal Women
This is a randomized, parallel two-arm clinical trial design to study the efficacy of time-restricted feeding on metabolic risk in postmenopausal women, who may be particularly vulnerable to disruption of circadian eating rhythms…
- Trial name
- NCT04893226
- Testing
- Time-Restricted Feeding (TRF)
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Julie Pendergast
Postmenopausal Syndrome
Ex Vivo High-Throughput Assay for Vaginal Community Post-menopausal Women
This purpose of this study is to collect vaginal microbial samples of postmenopausal women to assess the optimal conditions for cultivation and storage of the vaginal microbiota.
- Trial name
- FLORA (NCT02415868)
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Kimberly-Clark Corporation
Postmenopause
Effects of Breathing Training on Psychosocial Functioning and Heart Rate Variability in Postmenopausal Women With Depressive Symptoms-3
The specific aims of this study are: 1. To develop a breathing training protocol specifically designed to improve HRV and psychosocial functioning for postmenopausal women with depressive symptoms, 2.
- Trial name
- NCT01045811
- Testing
- Breathing training, Stress management
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Science and Technology Council, Taiwan
Post-menopausal Period
Pharmacokinetics, Pharmacodinamic and Safety of Testosterone Gel 1%
This is a Phase I, open-label, parallel trial to evaluate Pharmacokinetics, Pharmacodynamics and Safety of Testosterone gel 1% for topic usage in post-menopausal women, for 28 days
- Trial name
- NCT02667561
- Testing
- Testosterone gel 1% 2.2 mg, Testosterone gel 1% 4.4 mg, Testosterone gel 1% 8.8 mg
- Volunteers
- healthy volunteers welcome
- Sponsor
- Biolab Sanus Farmaceutica
Healthy
Bioavailability Study of Letrozole Tablets 2.5 mg of Dr.Reddy's Under Fasting Conditions
The purpose of this study is to compare bioavailability in healthy, post menopausal women subjects under fasting conditions.
- Trial name
- NCT01375452
- Testing
- Letrozole
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Osteoporosis
Bone Estrogen Strength Training
We started the Bone, Estrogen, Strength Training (BEST) study in the fall of 1995 at the University of Arizona, Tucson, Arizona. The BEST study is the largest of its kind.
- Trial name
- NCT00000399
- Testing
- Hormone replacement therapy, Strength training
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Visceral Obesity, Non-alcoholic Fatty Liver
Effect of Multi-ingredient on Visceral Adiposity & Non-alcoholic Fatty Liver Disease in Postmenopausal Women With Abdominal Obesity
This study aims to evaluate the effect of daily intake of a specific combination of different natural histidine-related amino acids in combination with dietary recommendations, in the reduction of visceral fat, as well as their…
- Conditions
- Visceral Obesity, Non-alcoholic Fatty Liver, Postmenopausal
- Trial name
- FATHIS+ (NCT06377631)
- Testing
- Multi-ingredient of L-histidine, L-serine, L-carnosine and N-Acetylcysteine
- Where
- 2 sites in Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Osteoporosis, Postmenopausal
Quercetin's Effect on Bone Health and Inflammatory Markers
Quercetin is a plant-based flavonoid that is naturally found in many fruits and vegetables, and is considered to be a potent antioxidant with several expected health benefits such as anti-inflammatory effects and bone-conserving…
- Trial name
- NCT05371340
- Testing
- Quercetin (500 mg)
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
Postmenopausal Disorder, Autonomic Imbalance
Inspiratory Muscle Training X CardioBreath App Effects On Vagal Modulation And Pulse Wave Velocity
Existing data points to relevant beneficial effects of respiratory exercises on cardiovascular health, with special regards to decreases on arterial pressure and improves on autonomic and vascular profiles, though mechanistics of…
- Conditions
- Postmenopausal Disorder, Autonomic Imbalance, Vascular Stiffness
- Trial name
- CardioBreath (NCT03672760)
- Testing
- CardioBreathApp, IMT PowerBreath
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul