Clinical trials: Post-menopause, open to volunteers
Obesity, Morbid, Postmenopause
Serum Estradiol and Endometrial Thickness After Bariatric Surgery in Postmenopausal Women With Obesity
Obesity changes how the body produces and processes estrogen. After menopause, higher estrogen exposure is linked to thickening of the lining of the womb (endometrium) and a higher risk of endometrial cancer.
- Conditions
- Obesity, Morbid, Postmenopause, Endometrial Thickening
- Trial name
- NCT07919054
- Testing
- Bariatric surgery, Conventional non-surgical obesity management
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Kasr El Aini Hospital
Muscle Mass and Strength, Menopause
Significance of Estrogen Status for Muscle Function, Physical Fitness, and Physiological Health Parameters - a Comparison of Age-matched Groups of Women Before and After Menopause.
As females age and transition through menopause, the decline in oestrogen level profoundly affects skeletal muscle mass and function.
- Trial name
- HER-MUSCLEX (NCT07649356)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mette Hansen
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Osteoporosis in Post-menopausal Women
Sequential Treatment With Romosozumab Followed by Denosumab vs. Zoledronic Acid for Gains in HIP BMD
Osteoporosis is associated with a high risk of fractures, disability, loss of independence, and excess mortality. Zoledronic acid is an established first-line treatment in Sweden, but many patients at high fracture risk remain at…
- Trial name
- STRONG-HIP (NCT07772609)
- Testing
- Romosozumab, Zoledronic Acid 5 MG in 5 ML Injection, Calcium 500 mg and Vitamin D3 800 IU
- Where
- 9 sites in Sweden
- Volunteers
- 216 people
- Sponsor
- Sahlgrenska University Hospital
Prehabilitation, Breast Cancer
Prehabilitation With Resistance-exercise Training for Breast Cancer Neoadjuvant Therapy
Breast cancer stands as the foremost cause of cancer-related deaths among women worldwide, with the highest incidence of any cancer type.
- Conditions
- Prehabilitation, Breast Cancer, Postmenopause, Resistance Training
- Trial name
- NEO STRONG (NCT06309290)
- Testing
- Prehabilitation with resistance-exercise training, Usual care program
- Where
- 2 sites in Chile
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Menopause
Brazilian Registry of Menopausal Health
The Brazilian Registry of Menopausal Health is a national study aimed to better understand the health and quality of life of participants aged 35 to 65 who are in the menopausal transition or postmenopausal phase, including…
- Trial name
- EMBRACE (NCT07005648)
- Where
- Brazil
- Volunteers
- 1,592 people, healthy volunteers welcome
- Sponsor
- Science Valley Research Institute
Menopause
Menopausal Symptoms Probiotic Study
In this study, we want to investigate if the active product consisting of a probiotic blend can potentiate the recirculation of active oestrogens into the bloodstream and help to mitigate menopause symptoms, which are closely…
- Trial name
- NCT06446869
- Testing
- Gyntima Menopause
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- Community Pharmacology Services Ltd
Perimenopause, Postmenopause
Effect of Lifestyle Intervention on Menopausal Symptoms, Sleep Quality, and Anxiety in Peri- and Postmenopausal Women
Menopause is a biological process characterized by the permanent cessation of menstruation, often accompanied by vasomotor symptoms, sleep disturbances, anxiety, and impaired quality of life.
- Conditions
- Perimenopause, Postmenopause, Menopause
- Trial name
- NCT07860645
- Testing
- Structured Lifestyle Education, Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
Low Back Pain, Postmenopause Women
Pain Catastrophizing, Fear of Movement, and Physical Activity in Postmenopausal Women With Chronic Low Back Pain
This observational study aims to examine the relationships between pain catastrophizing, fear of movement, and physical activity in postmenopausal women with chronic nonspecific low back pain.
- Trial name
- NCT07856498
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Istanbul Medipol University Hospital
Breast Cancer
Low Dose Exemestane vs Low Dose Tamoxifen in Post-menopausal Women at High Risk for Breast Cancer.
The purpose of the study is to to compare low dose of exemestane (babyexe) versus low dose of tamoxifen (babytam) in terms of change of quality of life from baseline to 12 months.
- Trial name
- BabyTears (NCT06364267)
- Testing
- Tamoxifen 10 MG, Exemestane 25 MG
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Andrea DeCensi
Obesity, Sarcopenia
Chrono-restricted Diet and Physical Activity as a New Preventive Strategy for Sarcopenia in Postmenopausal Women With Obesity and Type 2 Diabetes
The aim of TIMEDIAB is to demonstrate that early TRE (eTRE) combined to late (afternoon) exercise will outperform eTRE combined to morning exercise on muscle function as primary endpoint, and glucose homeostasis as secondary…
- Conditions
- Obesity, Sarcopenia, Post Menopause, Type 2 Diabetes
- Trial name
- TIMEDIAB (NCT07075133)
- Testing
- Antidiabetic diet (control), eTRE diet, Physical activity in the morning
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Insulin Resistance Syndrome
Hyperbaric Oxygen Therapy on Insulin Resistance in Postmenopause
Background: In postmenopausal females, Insulin resistance is commonly encountered in clinical setting. Hyperbaric oxygen therapy have been proposed effective in lowering blood glucose level and improving function.
- Trial name
- NCT06806345
- Testing
- Hyperbaric oxygen therapy, Hypoglycemic Drug
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Perimenopause, Postmenopause
Effects of a Dietary Supplement in Women With Late Perimenopause or Early Postmenopause
This study will evaluate the effects of a plant extract-based dietary supplement on menopausal symptoms and health indicators in women with late perimenopause or early postmenopause.
- Conditions
- Perimenopause, Postmenopause, Hot Flashes
- Trial name
- NCT07863973
- Testing
- Plant Extract-Based Dietary Supplement
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Stress Urinary Incontinence in Women
Perineal Ultrasound, Post-Void Residual, and Lower-Limb Alignment in Stress Incontinence
Stress urinary incontinence (SUI) in postmenopausal women is traditionally considered a local pelvic floor disorder, but emerging evidence suggests that spinopelvic and lower limb alignment may also contribute to continence…
- Trial name
- NCT07747727
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Benha University
Obesity & Overweight, Women
Effect Of Whole or Skimmed Milk Greek Yogurt on Integrated Muscle Protein Synthesis, Glucose Homeostasis, and Cognition in Post-Menopausal Women
The study will examine the impact of adding two servings per day of skimmed or whole milk Greek yogurt on integrated muscle protein synthesis (iMPS), blood sugar control, and cognition in post-menopausal women with overweight and…
- Conditions
- Obesity & Overweight, Women, Menopause
- Trial name
- NCT07705724
- Testing
- Skimmed vs Whole Milk Greek Yogurt
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Frozen Shoulder, Adhesive Capsulitis
Effect of Hormone Replacement Therapy on Physiotherapy Outcomes in Postmenopausal Women With Frozen Shoulder
The purpose of this study is to compare the effects of a physiotherapy program on pain levels, shoulder range of motion, functional status, pain catastrophizing, perceived change, sleep quality, and quality of life in…
- Conditions
- Frozen Shoulder, Adhesive Capsulitis, Adhesive Capsulitis of the Shoulder, Hormone Replacement Therapy, Post-Menopausal
- Trial name
- NCT07736027
- Testing
- Standardized Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
Menopause, Sexual Dysfunction
Transdermal Testosterone Gel for Female Sexual Interest and Arousal Disorder in Peri- and Post Menopause
Hypoactive sexual desire disorder (HSDD) is described as the most common form of female sexual dysfunction, particularly affecting peri- and postmenopausal women and is associated with significant distress and reduced quality of…
- Conditions
- Menopause, Sexual Dysfunction, Libido Disorder, Testosterone Deficiency
- Trial name
- TESTA MIND (NCT07408440)
- Testing
- Transdermal testosterone gel
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Joint Discomfort, Joint Pain, Stiffness, Function
JDS-HF3.0 Supplementation on Menopause Related Quality of Life Outcomes in Postmenopausal Women
The goal of this interventional study is to evaluate whether the study product can help improve quality of life and reduce common menopause symptoms-such as joint discomfort, hot flashes and night sweats-in women aged 50-70.
- Conditions
- Joint Discomfort, Joint Pain, Stiffness, Function, Joint Pain, Hot Flashes
- Trial name
- NCT07238478
- Testing
- JDS-HF3.0
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Bonafide Health