Clinical trials: Post-operative
Acute Kidney Injury
Preoperative Serum Albumin and Duration of Intraoperative Hypotension on Postoperative Acute Kidney Injury
Acute kidney injury is one of major adverse postoperative complications. research about postoperative acute kidney injury conclude that low preoperative albumin and intraoperative hypotension is associated to postoperative acute…
- Trial name
- NCT03882658
- Where
- China
- Volunteers
- 37,610 people
- Sponsor
- Peking University First Hospital
Lumbar Disc Herniation Surgery, Disc Herniation
Return to Activity After Surgery for Lumbar Disc Herniation
RCT investigating postoperative activity restriction after lumbar discectomy in patients treated with annular closure.
- Trial name
- NCT07667348
- Testing
- Postoperative therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Intrinsic Therapeutics
Colorectal Surgery, Colorectal Cancer
Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy
The purpose of this study is to evaluate the Colorectal Balloon Tube (hereinafter referred to as COLO-BT™) device, a single use, temporary intraluminal bypass device, intended to reduce contact of fecal content with an…
- Conditions
- Colorectal Surgery, Colorectal Cancer, Rectal/Anal, Ileostomy - Stoma
- Trial name
- COLO-BT (NCT05826743)
- Testing
- COLO BT™, Stoma Creation
- Where
- 3 sites in United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- JSR Medical Co., Ltd.
Short Bowel Syndrome
A Study of Teduglutide in Japanese Children With Short Bowel Syndrome Aged 4 Months or Older
The main aims of the study are to check for side effects from teduglutide. Participants will receive a daily injection of teduglutide just under the skin (subcutaneous) for 24 weeks. Then they are followed up for another 4 weeks.
- Trial name
- NCT05027308
- Testing
- Teduglutide
- Where
- 6 sites in Japan
- Volunteers
- 3 people
- Sponsor
- Takeda
Endometriosis, Infertility
Immediate Intra Uterine Isemination (IUI) Versus Expectant Management in Postoperative Endometriosis Patients
Is postoperative IUI better than expectant management in infertile endometriosis patients with good prognosis based on their EFI score? (A single centre randomised controlled trial).
- Trial name
- NCT02636400
- Testing
- controlled ovarian stimulation with gonadotropins + intrauterine insemination
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Neuropathic Pain, Chronic Pain
Post-operative Thoracic Epidural Analgesia and Incidence of Major Complications: a Large Retrospective Dual Center Experi-ence
A retrospective observational dual center study investigating side effects and major complications after thoracic epidural insertion according to local safety protocols.
- Conditions
- Neuropathic Pain, Chronic Pain, Thoracic Cancer
- Trial name
- NCT05909007
- Testing
- thoracic epidural insertion
- Where
- Greece
- Volunteers
- 1,145 people, healthy volunteers welcome
- Sponsor
- AHEPA University Hospital
Pulmonary Hypertension (Diagnosis), Pre-operative Assessment
GUARD-PH: Guided Use of AI-ECG for Risk Detection of PH in Surgery (GUARD-PH Trial)
This study is a prospective, open-label, randomized controlled trial designed to evaluate a new artificial intelligence (AI) tool for heart monitoring.
- Conditions
- Pulmonary Hypertension (Diagnosis), Pre-operative Assessment, Postoperative Complications (Cardiopulmonary), Treatment Outcomes
- Trial name
- GUARD-PH (NCT07344207)
- Testing
- Artificial Intelligence-Enabled Electrocardiography System
- Where
- Taiwan
- Volunteers
- 1,380 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Esophagectomy, Pneumonectomy
Stellate Ganglion Block
The purpose of this study is to determine if the addition of an ultrasound guided left sided stellate ganglion block with bupivacaine in patients undergoing esophagectomy, pneumonectomy, or lobectomy will result in lower rates of…
- Conditions
- Esophagectomy, Pneumonectomy, Lobectomy
- Trial name
- NCT06271707
- Testing
- 0.5% bupivacaine, Saline
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Minnesota
Orthopedic Surgery of Lower Extremity
Evaluation of Continuous Saphenous Nerve Block to Supplement a Continuous Sciatic Nerve Block After Ankle Surgery
A nerve block catheter is a small tube placed next to a nerve through a needle, and the needle is then removed. Numbing medicine is dripped through the tube to reduce pain sensation from the nerve.
- Trial name
- NCT01167907
- Testing
- 0.2% ropivacaine, saline
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Wake Forest University Health Sciences
Sarcoma
Preoperative IMRT for Soft Tissue Sarcoma of the Extremities and Trunk: Low Rate of Wound Complications
Postoperative wound healing complications following preoperative radiotherapy represent a severe problem in the treatment of malignant soft tissue tumors, and are reported to be 34% and more.
- Trial name
- NCT02785692
- Testing
- Radiation
- Where
- 2 sites in Switzerland
- Volunteers
- 67 people
- Sponsor
- Balgrist University Hospital
Cervical Cancer, Endometrial Cancer
Standard Versus Intensity-Modulated Pelvic Radiation Therapy in Treating Patients With Endometrial or Cervical Cancer
RATIONALE: Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause…
- Conditions
- Cervical Cancer, Endometrial Cancer, Gastrointestinal Complications, Perioperative/Postoperative Complications
- Trial name
- NCT01672892
- Testing
- Standard radiation therapy, intensity-modulated radiation therapy
- Where
- 137 sites in United States, Canada and 2 more
- Volunteers
- 289 people
- Sponsor
- Radiation Therapy Oncology Group
Dental Caries, Restored Decayed Teeth and Post-operative Sensitivity
Comparative Evaluation of Clinical Success of BIOFLX Crowns and SSC in Primary Molars
Although Stainless steel crowns (SSC) are the gold standard treatment modality for multi-surface carious lesion in paediatric patients, the quest for metal free, aesthetic restoration with comparable features that of SSC still…
- Trial name
- RCT (NCT07465211)
- Testing
- US Public Health Service modified criteria, The parental satisfaction
- Where
- India
- Volunteers
- 36 people
- Sponsor
- satish vishwanathaiah
Osteoarthritis of the Hip
Fascia Iliaca Block for Post-Operative Pain Control After Total Hip Arthroplasty
This study evaluates post-operative pain management and narcotic consumption in patients receiving a fascia iliaca block with local anesthetic versus patients receiving fascia iliaca block with saline for total hip arthroplasty.
- Trial name
- NCT02299271
- Testing
- Ropivacaine, Saline
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- The Christ Hospital
Hip Fracture of Intertrochanteric Type
Postoperative Analgesia With Local Infiltration After Hip Fracture Of Intertrochanteric Type
Reducing pain is an essential factor for early mobilization after osteosynthesis of intertrochanteric fractures. Systemic opioids have side effects that might obstruct mobilization and induce delirium and nausea.
- Trial name
- NCT01119209
- Testing
- Ropivacaine, Saline
- Where
- Denmark
- Volunteers
- 74 people
- Sponsor
- Odense University Hospital
Implant, Analgesia
Low Level Laser (LED) Use to Increase Dental Implant Stability and Post Operative Analgesia
Study hypothesis: Low level laser (LED) will reduce initial bone resorption and improve primary stability of dental implant. It will also reduces post operative pain compared to patient without treatment Implant osseointegration…
- Trial name
- NCT01097499
- Testing
- OsseoPulse device (Light emitting diode technology)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Inguinal Hernia Repair, Postoperative Pain
Visually Guided TAP Block in Laparoscopic TAPP Hernia Repair
This prospective, randomized clinical study aims to evaluate the effectiveness of the Transversus Abdominis Plane (TAP) block performed under direct laparoscopic vision in reducing postoperative pain and improving recovery after…
- Conditions
- Inguinal Hernia Repair, Postoperative Pain, TAP Block
- Trial name
- VIS-TAP-TAPP (NCT07264699)
- Testing
- Laparoscopic Transversus Abdominis Plane (TAP) Block with Bupivacaine
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
Hepatocellular Carcinoma, Beyond Milan Criteria
Neoadjuvant HAIC and PD-1 Plus Adjuvant PD-1 for High-risk Recurrent HCC
Surgical resection is the primary curative treatment for patients with hepatocellular carcinoma (HCC), with a 5-year overall survival rate of 60-80% post-surgery.
- Trial name
- NCT06467799
- Testing
- Neoadjuvant HAIC and PD-1 Plus Adjuvant PD-1
- Where
- China
- Volunteers
- 39 people
- Sponsor
- Sun Yat-sen University
Cataract, Retina Disorder
A Big Data-based Cohort Study for Cataract Patients
Cataract is an important cause of blindness and visual impairment worldwide. At present, the only effective treatment method is surgery.
- Trial name
- NCT05491798
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Sun Yat-sen University
Postoperative Complications, Intraoperative Complications
Uterine Transposition: Feasibility Study
This prospective nonrandomized multicenter phase I study, will evaluate the feasibility of performing uterine transposition before chemoradiation for rectal cancer and uterine reimplantation after the treatment.
- Conditions
- Postoperative Complications, Intraoperative Complications, Tissue Damage, Ovarian Failure
- Trial name
- NCT03040921
- Testing
- Uterine transposition.
- Where
- Brazil
- Volunteers
- 9 people
- Sponsor
- Hospital Erasto Gaertner
Size of Nasal Polyps, Control of Symptoms
Study of the Efficacy of Topical Nasal Steroids Patients With Nasal Polyps
Topical nasal steroid sprays are the mainstream treatment for patients with nasal polyps. Polyps tend to recur after surgery and topical nasal steroid sprays are used as the primary medical management to prevent continued growth.
- Trial name
- dexamethasone (NCT01777906)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Loma Linda University