Clinical trials: Post-operative Cardiac Surgery
Acute Kidney Injury
The Effects of Dexmedetomidine on Postoperative Renal Function in Valvular Heart Surgery
The purpose of study is to compare the incidence of acute kidney injury in patients receiving perioperative dexmedetomidine or placebo undergoing valvular heart surgery.
- Trial name
- NCT01886079
- Testing
- dexmedetomidine, Saline
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Digestive System Disease, Urologic Diseases
Low-dose Droperidol for Prevention of Postoperative Delirium in Elderly Patients After Non-cardiac Surgery
The aim of this multicenter, prospective, randomized, double-blind and large sample study is to explore the preventive effect of low-dose droperidol on POD in elderly patients after non-cardiac surgery, providing new approach for…
- Conditions
- Digestive System Disease, Urologic Diseases, Gynecological Disease, Orthopedic Surgery
- Trial name
- NCT05401058
- Testing
- Droperidol Injection, Saline
- Where
- 9 sites in China
- Volunteers
- 797 people
- Sponsor
- RenJi Hospital
Adverse Event, Physiotherapy
Adverse Events During Physiotherapy at Intensive Care Unit In Patients Undergoing Cardiac Surgery
This study aims to estimate the incidence of adverse events during physiotherapy at intensive care unit (ICU) in adult patients undergoing cardiac surgery and to identify predictors of those events.
- Conditions
- Adverse Event, Physiotherapy, Intensive Care Units, Cardiac Surgery
- Trial name
- Adephysio (NCT03552887)
- Testing
- Cardiac Surgery, Physiotherapy
- Volunteers
- 323 people
- Sponsor
- University of Sao Paulo General Hospital
Blood Pressure, Arrhythmias, Cardiac
Pulse Waveform and ECG Analysis in Postoperative Cardiac Surgical Patients
Observational study of 20 postoperative cardiac surgery patients. On admission to the ICU the patients will receive a noninvasive monitor recording arterial pulse waveform and ECG.
- Trial name
- NCT02350608
- Testing
- Noninvasive monitor
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Tampere University Hospital
Serratus Anterior Plane Block, Acute Pain
Combined SAPB in MICS
Minimally invasive cardiac surgery (MICS) has begun to be performed frequently in recent years. Compared to sternotomy, MISC reduces the risk of mediastinitis, leaves a more aesthetic scar, facilitates postoperative…
- Conditions
- Serratus Anterior Plane Block, Acute Pain, Postoperative Analgesia, Minimal Invasive Cardiac Surgery
- Trial name
- NCT06326320
- Testing
- Combined SAPB
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Delirium
Pilot and Feasibility Study of a Mirrors Intervention for Reducing Delirium in Older Cardiac Surgical Patients
This pilot cluster-randomised controlled trial aims to determine whether the use of bedside mirrors, as a clearly defined part of patients' postsurgical ICU care, can reduce delirium and improve outcomes in the older cardiac…
- Trial name
- NCT01599689
- Testing
- Mirrors Intervention
- Where
- United Kingdom
- Volunteers
- 223 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Surgery-Complications
Effects of Chest Physiotherapy Exercise in Prevention of Pre and Post Operative Complications By Cardiac Surgery
"A randomized control trial will be conducted among 189 patients who have undergone cardiac surgery in past. The participants for this research will be patients of Pakistan Institute of Cardiology, University of Lahore Teaching…
- Trial name
- NCT06378073
- Testing
- Incentive Spirometer, Numeric Pain Rating Scale
- Where
- 5 sites in Pakistan
- Volunteers
- 189 people
- Sponsor
- Superior University
Postoperative Quality of Recovery, Postoperative Quality of Recovery in the Postanesthesia Care Unit
Quality of Recovery in the Post-anesthesia Care Unit
This prospective observational study aims to identify the minimal clinically important difference of the QoR-PACU2 questionnaire.
- Trial name
- MiDiQoR (NCT06905353)
- Volunteers
- 188 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery Requiring Extracorporeal Circulation
Role of Mitochondrial Dysfunction in the Occurrence of Acute Kidney Injury (AKI) in Postoperative Cardiac Surgery
Cardiac Surgery and Acute Kidney Failure (AKI) post Surgery: AKI is a frequent complication in the immediate aftermath of cardiac surgery with an incidence varying from 5 to 40%.
- Trial name
- MIT-CEC (NCT04125069)
- Testing
- Coronary Artery Bypass Graft (CABG)
- Where
- France
- Volunteers
- 27 people
- Sponsor
- University Hospital Center of Martinique
Postoperative Residual Curarization, Neuromuscular Block
Reversal With Low Doses of Sugammadex in Patients Undergoing Non-cardiac Surgery
Neuromuscular blocking agents (NMBA) are among the most commonly used drugs during general anesthesia and may induce complete muscle paralysis.They are used clinically to facilitate endotracheal intubation and to optimize…
- Trial name
- NCT03460509
- Testing
- Sugammadex
- Volunteers
- 144 people
- Sponsor
- The Hospital of Vestfold
Post-operative Pain, Post-cardiac Surgery
Paravertebral Block for Improvement of Quality of Recovery Following Cardiac Surgery
This study aims to evaluate the efficacy of bilateral, paravertebral blockade (intervention) against sham blocks (control) placed prior to sternotomy in improving quality of recovery following cardiac surgery.
- Conditions
- Post-operative Pain, Post-cardiac Surgery, Cardiac Disease
- Trial name
- NCT06008821
- Testing
- Bilateral paravertebral block with 0.25% ropivicaine with 1:400,000 epinephrine
- Where
- Canada
- Volunteers
- 224 people
- Sponsor
- University of British Columbia
Pain, Postoperative, Cardiac Surgery
Pectoral Nerves Block to Relieve Post-sternotomy Pain After Cardiac Surgery
The primary objective of this study is to determine if the addition of PECS2 block provides superior post-operative analgesia for cardiac surgery patients after midline sternotomy compared to only standard-of-care post-operative…
- Trial name
- NCT04282239
- Testing
- PECS2 block, Ropivacaine 0.5% Injectable Solution, Lidocaine Epinephrine
- Where
- United States
- Sponsor
- NYU Langone Health
Postoperative Delirium
Dexmedetomidine vs Midazolam in Coronary Artery By-pass Surgery
The aim is to compare the incidence of postoperative delirium following coronary artery bypass grafting (CABG) between patients receiving dexmedetomidine and those receiving midazolam infusions.
- Trial name
- NCT07411794
- Testing
- Intravenous Dexmedetomidine infusion + Standard Anesthesia, intravenous midazolam infusion + Standard anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Cumhuriyet University
Atrial Fibrillation
Amiodarone to Prevent Post-Operative Arrhythmias
Rapid heart rhythms originating from the upper heart chambers (atrial tachyarrhythmias) are very common after open-heart surgery.
- Trial name
- NCT00251706
- Testing
- amiodarone
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- University of Calgary
Cardiac Surgery
Effect of Decreased Pump Prime Volume on Blood Transfusions and Postoperative Complications of Patients Undergoing High Risk Cardiac Surgical Procedures
The objective of this study is to evaluate the impact of reduced pump prime on blood transfusions and postoperative complications in patients at high risk of severe hemodilution during CPB.
- Trial name
- NCT00646373
- Testing
- Low Prime
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Vasoplegic Syndrome of Cardiac Surgery
Inotropic Effects of Vasopressin Versus Noradrenaline In Patients With Vasoplegic Syndrome After Cardiac Surgery
This is a randomized, double-blind clinical trial designed to compare the inotropic effects of vasopressin versus norepinephrine in patients who develop vasoplegic syndrome in the immediate postoperative period following cardiac…
- Trial name
- INVASC (NCT06934798)
- Testing
- Vasopressin intravenous infusion, Norepinephrine intravenous infusion
- Where
- Brazil
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Surgical Wound Infection
Effects of a New Antimicrobial Dressing on Wound Healing and Incidence of Sternal Wound Infections
The primary objective of this pivotal study is to determine if a new antimicrobial dressing, applied to the sternal incisions of cardiac surgical subjects, will demonstrate a decreased cumulative incidence rate(CI) of localized…
- Trial name
- NCT00203541
- Testing
- TELFA™ A.M.D. Island dressing
- Where
- United States
- Volunteers
- 1,100 people
- Sponsor
- Tyco Healthcare Group
Coronary Artery Disease
Evaluation of the Accuracy, Safety and Robustness of a Single-input-single-output (SISO) Model-based Predictive Closed-loop System to Guide Patient-individualized ICU Sedation
The aim of this study is to investigate the accuracy, safety and robustness of a single-input-single output (SISO) model-based predictive closed-loop system to guide patient-individualized ICU sedation.
- Trial name
- NCT00735631
- Testing
- SISO model-based predictive closed-loop system
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- University Hospital, Ghent
Cerebral Hemorrhage, Head Injury
Biomarkers Correlation With Volemia
The purpose of this study is to determine whether the Biomarkers (pro adrenomedullin (MR proADM), pro arginin vasopressin (CT proAVP), pro atrial natriuretic peptid (MR proANP), Pro Endothelin) changes at Day 2, Day 5 and Day 7…
- Conditions
- Cerebral Hemorrhage, Head Injury, Non Traumatic Post Surgery, Poly Trauma Patients Without Heart Failure
- Trial name
- ENVOL (NCT01858675)
- Testing
- Biomarkers, red blood cells and plasma assessment
- Where
- France
- Volunteers
- 66 people
- Sponsor
- ThermoFisher Scientific Brahms Biomarkers France
Intensive Care Unit, Cardiac Surgery
The Effect of Light Therapy on Post-Surgical Pain
Researchers aim to demonstrate that the use of phototherapy is feasible and may reduce acute postoperative pain based on recent literature.
- Trial name
- NCT05853731
- Testing
- Green light emitting diode, White light emitting diode
- Where
- United States
- Sponsor
- Mayo Clinic
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