Clinical trials: Post-operative Cardiac Surgery
High Risk for Postoperative Cardiovascular Events
Patients Undergoing Major Cancer Surgery: Incidence and Predictive Value for Postoperative Cardiac Events
The purpose of this study is to look at a new method for finding out if patients have a risk of heart complications from surgery.
- Trial name
- NCT01262222
- Testing
- endothelial function testing
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pediatric Patients, Congenital Heart Surgery
Pain Management of Pecto-intercostal Fascial Block Versus Intravenous Fentanyl After Pediatric Cardiac Surgery
Cardiac surgical patients often experience significant postoperative pain at the median sternotomy site. In pediatric cardiac surgery, the recommended pre bypass dose of fentanyl to blunt the hemodynamic and metabolic stress…
- Trial name
- NCT04945694
- Testing
- Ultrasound-guided bilateral pecto-intercostal fascial block, Intravenous fentanyl, Propofol
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Intellectual Frailty of Aging, Cardiovascular Diseases
Assessment of Frailty as a Risk Factor for Cardiac and Vascular Surgery
The purpose of this study is to assess the impact of frailty as a multidimensional risk factor on the outcomes of adult cardiac and vascular surgery.
- Conditions
- Intellectual Frailty of Aging, Cardiovascular Diseases, Myocardial Infarction, Vascular Diseases
- Trial name
- NCT02224222
- Where
- Hungary
- Volunteers
- 300 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Post-operative Pain
Sternotomies and PectoIntercostal Fascia Blocks in Fast-Track Cardiac Anesthesiology
This study is looking to see if a regional block placed on each side of the incision after surgery helps with pain relief. Ultrasound-guided pectointercostal fascia blocks will be placed at the conclusion of surgery following…
- Trial name
- SPIFFY (NCT05146453)
- Testing
- Pectointercostal fascia blocks
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Alberta
Postoperative Hemorrhage
Hetastarch and Bleeding Complications After Off-Pump Coronary Bypass Surgery
There has been continuing debate about whether use of hetastarch for volume replacement in coronary artery bypass surgery [CABG] increases the risk of postoperative bleeding.
- Trial name
- NCT00307138
- Testing
- hetastarch
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Kaiser Permanente
Cardiac Disease
Opioid Reduced Anesthesia With Parasternal CATheters on Postoperative Delirium After Cardiac Surgery
PostOperative Delirium (POD) is the most common neuropsychiatric complication following cardiac surgery and may be related to morphine consumption.
- Trial name
- ORACAT (NCT05880615)
- Testing
- collection of datas
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Atrial Fibrillation
Medtronic Reveal XT Study
While surgical treatment for atrial fibrillation (AF) has been performed for over 20 years, virtually all of the historical series reported only the recurrence of symptomatic AF and have used only intermittent electrocardiogram…
- Trial name
- NCT01526343
- Testing
- Reveal XT implantation
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- Washington University School of Medicine
Postoperative Pain, Sternotomy
Effect of Elastic Therapeutic Taping on Post-Sternotomy Pain in Coronary Artery Bypass Graft Surgery
This research study aims to find out whether elastic therapeutic taping can help reduce pain after heart surgery, specifically coronary artery bypass grafting (CABG), which is done using a surgical cut through the breastbone…
- Conditions
- Postoperative Pain, Sternotomy, Pain Management, Coronary Artery Bypass
- Trial name
- NCT06910215
- Testing
- Elastic therapeutic taping, Therapeutic Taping on Non-Surgical Areas
- Where
- Turkey (Türkiye)
- Volunteers
- 195 people
- Sponsor
- Abant Izzet Baysal University
Postoperative; Dysfunction Following Cardiac Surgery
Intra-aortic Balloon Counterpulsation in Patients Undergoing Cardiac Surgery
The hypothesis of the study is to evaluate if the preoperative placement of IABP reduces clinical complications in high-risk patients undergoing cardiac surgery.
- Trial name
- IABCS (NCT02143544)
- Testing
- Intra-aortic balloon pump.
- Where
- Brazil
- Volunteers
- 180 people
- Sponsor
- University of Sao Paulo
Myocardial Injury, Perioperative/Postoperative Complications
Comparison Arterial Blood Pressure and Cardiac Index-based Hemodynamic Management on Postoperative Myocardial Injury
The primary aim of this study is to compare mean arterial pressure (MAP) and cardiac index (CI) based intraoperative hemodynamic management in terms of postoperative high sensitive troponin elevation.
- Trial name
- NCT05391087
- Testing
- Mean arterial pressure based management, Cardiac index based management
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Saglik Bilimleri University
Cardiac Surgery With Cardiopulmonary Bypass
A Pilot Study to Investigate Fenoldopam Usage in the Prevention of Postoperative Renal Dysfunction in Patients at a High Risk for Renal Impairment During Cariopulmonary Bypass for Cardiac Surgery
The Primary objective is to reduce the incidence of postoperative renal dysfunction in a high-risk subset of patients undergoing cardiac surgery on cardiopulmonary bypass with Fenolopam, a selective dopamine-1 receptor agonist.
- Trial name
- NCT00467181
- Testing
- Fenoldopam
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Summa Health System
Cardiac Surgery, Vasoplegia
Reducing Acute Kidney Injury Occurence by Administering Angiotensin II
The aim of this study is to evaluate whether adding angiotensin II to the standard of care is superior compared to the standard of care alone with respect to kidney damage (personalized approach) after cardiac surgery.
- Conditions
- Cardiac Surgery, Vasoplegia, Hyperreninemia
- Trial name
- AIDED (NCT05199493)
- Testing
- Angiotensin II, Control
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Universität Münster
Atrial Fibrillation
Amiodarone to Prevent Post-Operative Arrhythmias
Rapid heart rhythms originating from the upper heart chambers (atrial tachyarrhythmias) are very common after open-heart surgery.
- Trial name
- NCT00251706
- Testing
- amiodarone
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- University of Calgary
Mechanical Ventilation, Coronary Bypass Surgery
The Effect of Preoperative Values on Mortality in Patients Undergoing Open Heart Surgery
Open heart surgeries are one of the major and complicated surgeries performed frequently in the world due to the prolongation of life expectancy and developments in medicine.
- Conditions
- Mechanical Ventilation, Coronary Bypass Surgery, Postoperative Complications
- Trial name
- NCT04741555
- Where
- Turkey (Türkiye)
- Volunteers
- 1,600 people
- Sponsor
- Karadeniz Technical University
Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery (CABG)
Examining the Effects of Video-Assisted Discharge Education After Coronary Artery Bypass Graft Surgery on Patient Satisfaction and Anxiety
This study was conducted to examine the effects of standard and individualized video-assisted discharge education on patient satisfaction and anxiety levels following Coronary Artery Bypass Graft (CABG) surgery.
- Conditions
- Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery (CABG), Postoperative Discharge Education
- Trial name
- NCT07528859
- Testing
- video discharge education, individual video discharge training, discharge education
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Heart; Surgery, Heart, Functional Disturbance as Result
Multifunctional Approach in Cardiac Surgery
Postoperative pain and swallowing disorders are complex, multifactorial phenomenon that frequently occur after cardiac surgery. Preoperative anxiety and the interaction between sex and other sociocultural factors may predict…
- Trial name
- TITANIC (NCT05824598)
- Testing
- Multifunctional rehabilitation treatment
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Microvascular Rarefaction, Heart Valve Diseases
Evaluation of Systemic Microcirculation of Patients Undergoing Heart Valve Surgery
The study aims to study the systemic microcirculation in adult patients hospitalized at a quaternary public hospital during the preoperative and immediate postoperative periods of heart valve surgery and correlations to their…
- Conditions
- Microvascular Rarefaction, Heart Valve Diseases, Extracorporeal Circulation
- Trial name
- NCT05728047
- Testing
- Evaluation of sublingual microcirculation with side-stream dark field imaging (cytocam)
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Pediatric Cardiac Surgery
Effect of Dexamethasone as an Adjuvant to Bupivacaine in Bilateral Erector Spinae Block on Postoperative Pain and Diaphragmatic Function After Pediatric Cardiac Surgeries : A Randomized Controlled Clinical Trial
The aim of this study is to figure out the efficacy of dexamethasone addition to bupivacaine versus bupivacaine alone in bilateral erector spinae plane block on postoperative analgesia after pediatric cardiac surgeries
- Trial name
- NCT05536063
- Testing
- bilateral erector spinae plane block in pediatric cardiac surgeries
- Volunteers
- 75 people
- Sponsor
- Assiut University
Postoperative Atrial Fibrillation
Effect of Alpha-Lipoic Acid Supplementation on the Incidence of Postoperative Atrial Fibrillation in Cardiac Surgery Patients
ALA is administered orally since it is without difficulty absorbed in the stomach. ALA goes through the blood brain barrier and does not show toxic effects and actions at doses used for prophylactic and therapeutic purposes.
- Trial name
- NCT06151652
- Testing
- Alpha Lipoic Acid 600 MG Oral Tablet
- Where
- Egypt
- Volunteers
- 350 people
- Sponsor
- Ain Shams University
Cerebral Desaturation, Surgery
Cerebral Oximetry to Reduce Organ Dysfunction After Non-cardiac Surgery
Number of elderly patients requiring general anesthesia for major surgical procedures is increasing dramatically. It is estimated that 20% of these patients will develop major complications after surgery.
- Trial name
- NCT03861026
- Testing
- Bilateral NIRS (Masimo, O3TM Regional Oximetry)
- Where
- 2 sites in Canada
- Volunteers
- 101 people
- Sponsor
- University Health Network, Toronto
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