Clinical trials: Post-operative Cognitive Dysfunction
Post-operative Delirium, Decision Support Systems, Clinical
Mitigation of Postoperative Delirium in High-Risk Patients
Among patients with cognitive impairment (CI) that undergo surgery, the risk for developing postoperative delirium (POD) is high (50%) and associated with further morbidity and mortality.
- Conditions
- Post-operative Delirium, Decision Support Systems, Clinical, Cognitive Impairment
- Trial name
- NCT05777187
- Testing
- Clinical Decision Support
- Where
- United States
- Volunteers
- 7,412 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Post Operative Cognitive Dysfunction
Post-Operative Cognitive Dysfunction in Normal Aging Patients Undergoing Elective Orthopedic Surgery
Post-operative cognitive dysfunction (POCD) is a common concern for aging patients undergoing elective orthopedic surgery and significantly effects health outcomes.
- Trial name
- POCD (NCT04267328)
- Testing
- Elective Orthopedic Surgery
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- HealthPartners Institute
Alzheimers Disease, Postoperative Delirium
Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care
This study will examine the hypothesis that changes in the cognition (i.e. thinking and memory) after anesthesia and surgery are correlated with changes in markers of Alzheimers Disease in the fluid around the brain and spinal…
- Conditions
- Alzheimers Disease, Postoperative Delirium, Post Operative Cognitive Dysfunction
- Trial name
- MADCO-PC (NCT01993836)
- Testing
- Total intravenous anesthesia with propofol, General anesthesia with isoflurane
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Duke University
Post Operative Pain
Parent Nurse Controlled Analgesic in Pediatric Patients With Developmental Delay
The purpose of this study is to compare, the safety, efficacy and level of parent and nurse satisfaction with three methods of opioid administration post-operatively in children (4-18 years of age) with developmental delay.
- Trial name
- PNCA (NCT00743730)
- Testing
- Pain and standard side effect management for PNCA with basal method., Pain and standard side effect management with PNCA without basal, Pain and standard side effect management with IV on an as needed basis method.
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Medical College of Wisconsin
Post Operative Cognitive Dysfunction, Emergence From Anesthesia
Reversal of General Anesthesia With Methylphenidate
The aim of this study is to investigate whether methylphenidate (Ritalin) can actively induce emergence from general anesthesia in patients having a pancreaticoduodenectomy (Whipple procedure), a pancreatectomy, or a…
- Trial name
- NCT02051452
- Testing
- Methylphenidate, Saline
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Massachusetts General Hospital