Clinical trials: Post-operative Hypovolemia
Hypovolemia, Sepsis
A Prospective Observational Study of the Expectations and Physiological Effects of Fluid Bolus Therapy
This prospective observational study aims to (i) asses intensive care doctors trigger for and the expected physiological response to a fluid bolus and (ii) evaluate the patient's actual physiological response to a single fluid…
- Conditions
- Hypovolemia, Sepsis, Post-operative Hypovolemia, Fluid Therapy
- Trial name
- NCT03178578
- Where
- 3 sites in Australia, Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Anesthesia, Perioperative/Postoperative Complications
Use of Heart-lung Interaction to Predict Haemodynamic Tolerance to the Open Lung Approach With Individualised PEEP
This is an observational, prospective, single-centre study that will focus on patients undergoing major non-cardiac surgery requiring invasive mechanical ventilation and invasive blood pressure monitoring Hypotheses: A positive…
- Conditions
- Anesthesia, Perioperative/Postoperative Complications, Hypovolemia, Haemodynamic Instability
- Trial name
- HiPEEP (NCT06123039)
- Testing
- Tidal Volume Challenge, Recruitment maneuver obtaining individualised PEEP
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe
Hypovolemia, Hypotension
Dynamic Parameters in Evaluation of Fluid Responsiveness
Intravenous infusion of fluids in patients after surgery is a very important part of treatment. However, administering too much or too little fluid can lengthen the stay in the intensive care unit or even harm the patient.
- Conditions
- Hypovolemia, Hypotension, Surgery
- Trial name
- NCT04283851
- Testing
- testing functional haemodynamic parameters for preload assessment
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- Charles University, Czech Republic
Post Operative Hemorrhage, Transfusion Related Complication
Monitoring Noninvasively for Infusion and Transfusion Optimization
This is a multicenter, cluster randomized controlled trial to assess the effects of an optimized intraoperative fluid and blood management strategy on postoperative complications.
- Conditions
- Post Operative Hemorrhage, Transfusion Related Complication, Blood Transfusion Associated Adverse Reactions, Hypovolemia
- Trial name
- NCT04388722
- Testing
- Pulse CO-Oximeter Sensor
- Sponsor
- Masimo Corporation
Hypovolemia, Perioperative/Postoperative Complications
Detection of Hypovolemia in the Elderly Patient Undergoing Surgery
Prospective observational study, in which the primary aim of the study is to determine the incidence of perioperative hypovolemia in the elderly patient scheduled for major surgery.
- Trial name
- HOOI (NCT06229938)
- Testing
- Passive leg raise manoeuvre
- Where
- Netherlands
- Volunteers
- 143 people
- Sponsor
- Amsterdam UMC, location VUmc
Anesthesia, ERAS
Goal-Directed Fluid Therapy in Patients Undergoing Lower Limb Surgeries
Controlling the amount of fluids given to patients in perioperative setting can significantly influence their outcomes.
- Conditions
- Anesthesia, ERAS, Fluid Overload, Hypovolemia; Surgical Shock
- Trial name
- NCT06133257
- Testing
- Goal-Directed Fluid Therapy guided by Inferior Vena Cava Collapsibility Index, standard fluid management
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Perioperative/Postoperative Complications, Hypovolemia
Goal-directed Therapy in High-risk Surgery
There is growing evidence that the risk of postoperative complications can be decreased by optimizing the amount and type of infusion fluids given during surgery, steered by goal-directed therapy based on flow-related hemodynamic…
- Conditions
- Perioperative/Postoperative Complications, Hypovolemia, Hypoxia
- Trial name
- NCT01681238
- Testing
- Protocol group 2, Protocol group 1
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Guangzhou First People's Hospital