Clinical trials: Post-operative Nausea
Postoperative Nausea and Vomiting
The Effects of Gabapentin and Ramosetron on Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
This study was designed to compare the effects of gabapentin and ramosetron on PONV in patients undergoing laparoscopic gynecologic surgery.
- Trial name
- PONV (NCT02617121)
- Testing
- Gabapentin, Ramosetron, Gabapentin and Ramosetron
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hallym University Medical Center
Laparoscopic Surgery, Breathing Exercise
The Effect of Respiratory Exercise After Laparoscopic Surgery
Laparoscopic surgery (LS) enables the patient to experience the desired result with smaller incisions in the postoperative period, more aesthetically, stress-free and less painful.
- Trial name
- NCT05624346
- Testing
- Deep-Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Postoperative Nausea and Vomiting
Antiemetic Efficacy and Safety of Dexamethasone in Obstetric Surgical Patients
This is a randomised controlled double blinded clinical trial to determine the antiemetic efficacy and safety of either 8 mg of dexamethasone or normal saline (placebo) given 1 hour before induction of either spinal or general…
- Trial name
- NCT01028547
- Testing
- dexamethasone, normal saline
- Where
- Uganda
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Makerere University
Quality of Life, Breastfeeding
Quality of Recovery in Parturients Consumed Preoperative Carbohydrate Fluid for Elective Cesarean Delivery
The establishment of the Enhanced Recovery After Cesarean protocols resulted in to the production of specific care pathways with the aim of optimizing recovery after cesarean delivery (CD) and to reduce the costs to the health…
- Conditions
- Quality of Life, Breastfeeding, Postoperative Pain, Postoperative Nausea
- Trial name
- QoR-10 (NCT05841693)
- Testing
- Carbohydrate
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Pain, Acute, Nausea
Enhanced Recovery Strategies in Elective Breast Surgery
Postoperative pain, nausea, and vomiting are frustrating sequelae of elective breast surgery. Poorly managed postoperative pain can lead to increased opioid use, increased postoperative nausea and vomiting (PONV), delayed return…
- Conditions
- Pain, Acute, Nausea, Vomiting, Postoperative, Opioid Use
- Trial name
- NCT03187080
- Testing
- Paravertebral block procedure using either local anesthetic (0.25% bupivacaine) or sterile saline, Enhanced recovery after breast surgery (ERABS) strategies, Paravertebral block using local anesthetic
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Post Operative Nausea and Vomiting
Mirtazapine Versus Dexamethasone in Preventing Postoperative Nausea and Vomiting
Mirtazapine is a noradrenergic and specific serotonergic antidepressant. Its antagonist at the 5HT3 receptor may help to prevent nausea and vomiting.
- Trial name
- NCT04547842
- Testing
- Mirtazapine 30 MG, Dexamethasone
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Fasting
The Effects of Carbohydrate-electrolyte Solution on Metabolic Responses in Paediatric Patients
The aim of this study is to evaluate the effects of oral administration of carbohydrate-electrolyte-containing fluid, compared to standard clear fluid during preoperative fasting on metabolic responses, preoperative anxiety and…
- Trial name
- NCT05729100
- Testing
- Oral carbohydrate-electrolyte solution, Control
- Where
- Indonesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Postoperative Nausea and Vomiting
Use of Baxter Animated Retching Faces (BARF) Scale to Measure Nausea in Children Who Speak Spanish
Pediatric research in the management of nausea has been limited by the absence of a reliable method to quantify the intensity of this subjective symptom.
- Trial name
- NCT02007109
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Enhanced Recovery After Surgery, Hospital Stay
The Impact of Enhanced Recovery After Surgery in Orthognathic Surgery
Aim: Orthognathic surgeries are generally associated with blood loss, swelling, postoperative nausea vomiting (PONV), and pain. The aim of this study is to improve postoperative outcome in patients undergoing orthognatic…
- Conditions
- Enhanced Recovery After Surgery, Hospital Stay, Postoperative Nausea and Vomiting, Pain, Postoperative
- Trial name
- NCT04596774
- Testing
- Traditional Approach, Enhanced Recovery After Surgery (ERAS) Approach
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Postoperative Nausea and Vomiting
Dexamethasone for the Prevention of Post-operative Nausea and Vomiting in Patients Undergoing Cesarean Sections
Patients who present for scheduled (non-emergent) cesarean section will be given either intravenous dexamethasone or placebo prior to receiving a duramorph containing spinal anesthetic.
- Trial name
- NCT01734161
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
PONV, Regional Anaesthesia
Incidence and Factors Associated With PONV in Regional Anaesthesia
Post-operative nausea and vomiting (PONV) is one of the complications associated with surgery and anaesthesia. The main aim of the study is to determine the incidence of post-operative nausea and vomiting among surgical patients…
- Trial name
- NCT03835234
- Where
- Uganda
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Makerere University
Postoperative Nausea and Vomiting
Transdermal Nicotine in Female Patients at High Risk for Post Operative Nausea and/or Vomiting (PONV)
The purpose of this study is to see if the nicotine patch reduces post operative nausea and/or vomiting (PONV) among non-smoking patients who are at high risk of PONV.
- Trial name
- NCT00775749
- Testing
- transdermal nicotine patch
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ochsner Health System
Cholecystitis, Pain
The Effect of Hyoscine-n-butylbromide on Nausea and Pain in Laparoscopic Cholecystectomy
The goal of this randomized double blind study is to compare the effects of hyoscine-n-butylbromide, and ondansetron on postoperative nausea-vomiting, and pain in patients who underwent laparoscopic cholecystectomy.The main…
- Conditions
- Cholecystitis, Pain, Nausea
- Trial name
- NCT06927817
- Testing
- hyoscine-n-butylbromide, ondansetron, • hyoscine-n-butylbromide • ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Postoperative Nausea and Vomiting, Breast Cancer Female
Ramosetron on Late PONV (Postoperative Nausea and Vomiting)
The purpose of this study was to evaluate the effectiveness of additional ramosetron injection for controlling late postoperative nausea and vomiting (PONV) after breast surgery in high risk PONV patients.
- Trial name
- NCT05326360
- Testing
- Ramosetron Hydrochloride
- Where
- South Korea
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Post-operative Nausea and Vomiting, Laparoscopic Sleeve Gastrectomy
Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve Gastrectomy
Bariatric surgery remains the most effective therapy for obesity. Postoperative nausea and vomiting (PONV) are commonly reported following bariatric surgery.
- Trial name
- NCT03435003
- Testing
- Aprepitant 80 mg Oral Capsule, scopolamine transdermal, Total intravenous anesthesia
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Opioid Use, Pain, Postoperative
Outcome of Multimodal Anesthesia Bern
In the context of the ongoing opioid crisis in the USA and Europe, reducing perioperative opioid use is a growing priority. Multimodal anesthesia (MMA) offers a patient-centered alternative to opioid-free anesthesia, combining…
- Conditions
- Opioid Use, Pain, Postoperative, Postoperative Complications, Postoperative Nausea
- Trial name
- NCT06985069
- Testing
- General anesthesia applying multimodal anesthesia, General anesthesia using conventional opioid-based regimen
- Where
- Switzerland
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Postoperative Nausea and Vomiting
Dextrose Containing Fluid and the Postoperative Nausea and Vomiting in the Gynecologic Laparoscopic Surgery
The investigators tested the hypothesis that administration of intravenous dextrose as a maintenance fluid in gynecologic laparoscopic surgery would reduce the incidence and severity of postoperative nausea and vomiting (PONV)…
- Trial name
- NCT03139383
- Testing
- dextrose solution, saline solution
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Inguinal Hernia
Effect of IV Nalbuphine on Nausea and Vomiting Following Intrathecal Morphine
the study aimed to investigate the effect of Iv nalbuphine on postoperative nausea and vomiting and pain with intrathecal morphine on inguinal hernia repair surgery.
- Trial name
- NCT05704673
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Total Intravenous Anesthesia, Desflurane
TIVA Versus Desfluran Anaesthesia in Patients Undergoing Bariatric Surgery
Many factors during laparascopic surgery leads to PONV (postoperative nausea and vomiting), such as C02 insufflations causing peritoneal stretch and irritation and type of anaesthesia given during surgery.
- Conditions
- Total Intravenous Anesthesia, Desflurane, Obesity, Pain, Postoperative
- Trial name
- NCT03727607
- Testing
- Desflurane
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Laparoscopic Surgery, PONV
Effects of Auricular Acupressure on the Management of Postoperative Nausea and Vomiting After Gynecological Laparoscopic Surgeries
Auricular acupressure is easily accessible and easily performed, and can significantly relieve PONV symptoms, and improve patient's satisfaction in women receiving general anesthesia for gynecological surgeries.
- Conditions
- Laparoscopic Surgery, PONV, Auricular Acupressure
- Trial name
- NCT05540236
- Testing
- auricular acupressure
- Where
- Taiwan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Cathay General Hospital