Clinical trials: Post-operative Nausea
Postoperative Nausea, Postoperative Vomiting
Comparison of IV Fluid Loading and Ondansetron in Reduction of PONV After LC
This study is designed to examine the incidence of postoperative nausea and vomiting during 24 hours after elective laparoscopic cholecystectomy in patients receiving preoperative intravenous fluid loading (group F), ondansetron…
- Conditions
- Postoperative Nausea, Postoperative Vomiting, Postoperative Nausea and Vomiting
- Trial name
- NCT03141645
- Testing
- Fluid loading, Ondansetron
- Where
- Thailand
- Volunteers
- 171 people
- Sponsor
- Siriraj Hospital
PONV
Phase IIIb Study of APD421 in Combination as PONV Prophylaxis
A comparison of the efficacy of APD421 and placebo when combined with a standard anti-emetic in the prevention of PONV in patients at high risk of Post-operative Nausea and Vomiting (PONV).
- Trial name
- NCT02337062
- Testing
- APD421
- Where
- 25 sites in United States, France and 1 more
- Volunteers
- 1,147 people
- Sponsor
- Acacia Pharma Ltd
Nausea and Vomiting, Postoperative, Septoplasty/Septorhinoplasty
Effect of Fresh Gas Flow Differences on Postoperative Nausea and Vomiting
The aim of this study is to investigate the effect of fresh gas flow applied during general anesthesia on the incidence of postoperative nausea and vomiting in patients undergoing septorhinoplasty surgery.
- Trial name
- NCT06952946
- Testing
- 0.5 lt/dk fresh gas flow, 2 lt/dk fresh gas flow, 4 lt/dk fresh gas flow
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Adiyaman University Research Hospital
Knee Osteoarthritis, Arthropathy of Knee Joint
Outcome After Total Knee Arthroplasty Under General or Spinal Anesthesia
Previous retrospective database studies suggest that total knee arthroplasty (TKA) surgery under spinal anesthesia has less complications than when performed under general anesthesia.
- Conditions
- Knee Osteoarthritis, Arthropathy of Knee Joint, Knee Pain Chronic, Rheumatoid Arthritis
- Trial name
- NCT03364088
- Testing
- Spinal anesthesia with tourniquet, Spinal anesthesia without tourniquet, General anesthesia with tourniquet
- Where
- Finland
- Volunteers
- 402 people
- Sponsor
- Riku Antero Palanne
Laparoscopy, Postoperative Nausea and Vomiting
Haloperidol and Dexamethasone Towards Postoperative Nausea and Pain in Adult After Laparoscopy
This study aim to find out the effectiveness of 1 mg intravenous haloperidol compared to 5 mg intravenous dexamethasone to prevent the occurrence of nausea and vomiting also as pain control in adult patients after laparoscopic…
- Trial name
- NCT05246631
- Testing
- Dexamethasone injection, Haloperidol Injection
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Universitas Indonesia
Arrhythmia, Droperidol
Gender Influence on Torsadogenic Actions of Droperidol.
Postoperative nausea and vomiting (PONV) is a quite common complication affecting patients undergoing general anesthesia. There are a few pharmacological agents of well known effectiveness in reducing the risk of PONV.
- Trial name
- NCT03944681
- Testing
- Droperidol Injectable Solution
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Gdansk
Laparoscopic Surgery, Breathing Exercise
The Effect of Respiratory Exercise After Laparoscopic Surgery
Laparoscopic surgery (LS) enables the patient to experience the desired result with smaller incisions in the postoperative period, more aesthetically, stress-free and less painful.
- Trial name
- NCT05624346
- Testing
- Deep-Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Nausea and Vomiting, Postoperative
Granisteron Versus Metoclopramide in Laparoscopic Cholecystectomy
Study aims at comparing the effect of granisteron with that of metoclopramide in patients undergoing lab cholecystectomy
- Trial name
- NCT04899817
- Testing
- Granisetron
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Nausea and Vomiting, Postoperative Pain
Postoperative Nausea, Vomiting and Pain After Bariatric Surgery - a National Registry Study
Around 4,000-5,000 bariatric (weight-loss) operations are performed in Sweden every year. Nausea, vomiting and pain are common immediately after these operations, cause considerable suffering and increase the intensity and length…
- Conditions
- Postoperative Nausea and Vomiting, Postoperative Pain, Obesity, Morbid, Bariatric Surgery
- Trial name
- BAROSPOR (NCT07797374)
- Where
- 2 sites in Sweden
- Volunteers
- 30,000 people
- Sponsor
- Umeå University
Postoperative Nausea and Vomiting
Postoperative Nausea and Vomiting: to Estimate the Incidence and Risk Factors in a Tertiary Teaching Hospital
Postoperative nausea and vomiting (PONV) is a frequent complication of surgery and anesthesia. The aim of this study is to estimate the incidence and the risk factors of PONV at Jordan University Hospital over one year period.
- Trial name
- NCT02689128
- Where
- Jordan
- Volunteers
- 6,000 people
- Sponsor
- University of Jordan
Laparoscopic Colorectal Surgery, Postoperative Analgesia
Effect of Oliceridine Analgesia on Postoperative Nause and Vomiting
Postoperative nausea and vomiting (PONV) is common after surgery and impede rapid recovery after surgery. Patients who undergo laparoscopic colorectal surgery are more likely to develop PONV due to the pneumoperitoneum…
- Conditions
- Laparoscopic Colorectal Surgery, Postoperative Analgesia, Oliceridine, Morphine
- Trial name
- NCT06411665
- Testing
- Oliceridine, Morphine
- Where
- China
- Volunteers
- 252 people
- Sponsor
- Peking University First Hospital
Postoperative Nausea and Vomiting
Palonosetron vs Combination of Granisetron and Dexamethasone in Preventing PONV in Laparoscopic Cholecystectomy.
This is a prospective, randomized, double-blinded study comparing the post-operative nausea vomiting (PONV) profile following administration of intraoperative palonosetron alone and the combination of granisetron and…
- Trial name
- NCT06043336
- Testing
- Dexamethasone, granisetron & palonosetron
- Where
- Malaysia
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
PONV
Acupuncture for Prevention of Postoperative Nausea and Vomiting
The aim of this study is to compare the single point stimulation (P6) and double point stimulation (P6+ST36) performed before anesthesia induction with standard treatment in terms of PONV development and postoperative anti-emetic…
- Trial name
- PONV (NCT04866121)
- Testing
- Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Nigde Omer Halisdemir University
Post Operative Pain, Nausea and Vomiting
Reduction of Postoperative Pain, Nausea and Vomiting
Aim of this prospective study was to assess the quality of postoperative care in a postoperative anaesthesia care unit (PACU) using postoperative pain, nausea and vomiting as well as their reduction as quality markers.
- Trial name
- NCT01718132
- Where
- Switzerland
- Volunteers
- 16,309 people
- Sponsor
- Triemli Hospital
PONV
Comparison Between Opioid-Free Anaesthesia Versus Opioid Based Anesthesia in Reduction Postoperative Nausea and Vomiting (PONV)After Thoracoscopic Lung Resection.
The invistigators hypothesized that a protocolized OFA technique would lower the occurance of PONV in patients undergoing thoracoscopic lung surgery compared to standard opioid-based anaesthesia.
- Trial name
- NCT07806162
- Testing
- Opioid Free Anaesthesia, conventential opioid-based anaesthesia (OBA,
- Volunteers
- 120 people
- Sponsor
- Sohag University
Laparoscopic Cholecystectomy, Pain
ICOUGH Bundle and Postoperative Pain and Nausea After Laparoscopic Cholecystectomy
This study will use a randomized controlled experimental research design. The population of the study will consist of all adult patients who undergo laparoscopic cholecystectomy at the General Surgery Clinic of Atatürk University…
- Conditions
- Laparoscopic Cholecystectomy, Pain, ICOUGH, NAUSEA
- Trial name
- ICOUGHBundle (NCT06755970)
- Testing
- ICOUGH
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Postoperative Pain, Postoperative Nausea and Vomiting
Pre-pectoral AlloDerm® to Reinforce Tissues in Tissue Expander Breast Reconstruction
Primary Objective: To describe postoperative static pain scores on the Pain Visual Analog Scale at Day 1 in a population of women undergoing bilateral mastectomy followed by immediate, bilateral pre-pectoral tissue expander…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Quality of Life, Breast Cancer
- Trial name
- NCT03195322
- Testing
- Pre-pectoral Tissue Expander
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Osteoarthritis, Knee
Efficacy and Safety of Single, Low-dose Dexamethasone in Patients After Total Knee Arthroplasty
This study was conducted to determine the efficacy of an additional preemptive, single, low-dose dexamethasone in terms of incidence and severity of postoperative nausea/vomiting (PONV), pain level, and the safety in terms of…
- Trial name
- NCT01612702
- Testing
- Dexamethasone
- Where
- South Korea
- Volunteers
- 291 people
- Sponsor
- Tae Kyun Kim
Laparoscopic Sleeve Gastrectomy, Postoperative Nausea and Vomiting
Randomized, Controlled, Single-blind Exploratory Study of the Efficacy and Safety of Wrist and Ankle Acupuncture Intervention on Nausea, Vomiting and Pain After Sleeve Gastric Surgery in Women
PONV is the most common clinical presentation after surgical procedures beyond pain. A retrospective study of our center found that the postoperative incidence of LSG was 77.4%.
- Trial name
- NCT05873270
- Testing
- Wrist and ankle acupuncture
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- LILIAN GAO
Postoperative Nausea and Vomiting, Pain, Postoperative
Guanfacine for PONV and Pain After Sinus Surgery
Postoperative nausea and vomiting (PONV) and pain are the most common causes of Post Anesthesia Care Unit (PACU) discharge delay, with untreated PONV occurring in 20-30% of post-surgical patients.
- Trial name
- NCT02882854
- Testing
- Guanfacine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Vanderbilt University Medical Center