Clinical trials: Post-operative Pain Control
Anesthesia and Analgesia, Anesthesia, Endotracheal
Opioid Free Versus Opioid Balanced Anesthesia in Ophthalmic Surgery
Anesthesia without the use of opioid (Opioid free anesthesia) is an alternative to conventional opioid balanced anesthesia, with less post operative nausea and vomiting, and comparable analgesia.
- Trial name
- NCT06382831
- Testing
- Dexmedetomidine, Fentanyl
- Volunteers
- 104 people
- Sponsor
- Universitas Indonesia
Fistula in Ano
Post-op Pain After Fistula Laser Closure or Ligation of the Intersphincteric Tract for Anal Fistula
This is a prospective, double-blinded randomised controlled trial conducted at two tertiary hospitals by a credentialed colorectal surgeon.
- Trial name
- LASERLIFT (NCT06212739)
- Testing
- Laser, LIFT
- Where
- Malaysia
- Volunteers
- 56 people
- Sponsor
- University of Malaya
Post Operative Pain Control
Efficacy of Ultrasound Guided Erector Spinae Plane Block Versus Ultrasound Guided Serratus Anterior Plane Block for Postoperative Pain Control Following Video-assisted Thoracoscopic Surgeries (VATS): Randomized Control Trial
The aim of the study is to compare the analgesic efficacy of Erector spinae plane block versus Serratus anterior plane block in patients undergoing video-assisted thoracoscopic surgeries.
- Trial name
- NCT07360028
- Testing
- Erector Spinae (ESP) Block with Bupivacaine (Marcaine®), Serratus anterior plane block (SAP)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Postoperative Analgesia, Pain Management
Comparison of Intrathecal Morphine and Rectus Sheath Block for Postoperative Pain Management After Lower Abdominal Surgery With Midline Incision
This study aims to evaluate the efficacy of intrathecal morphine and rectus sheath block compared with standard postoperative analgesia for pain management in patients undergoing lower abdominal surgery with a midline incision.
- Trial name
- NCT07489872
- Testing
- Intrathecal Morphine, Rectus Sheath Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Marmara University
Pain, Postoperative
Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
The purpose of this study is to evaluate the patient experience when using gabapentin with other pain control medications after posterior spinal fusion surgery for scoliosis in adolescents.
- Trial name
- NCT01977937
- Testing
- Gabapentin 250mg/5mL NDC:59762-5025-01, Simple Syrup
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Oregon Health and Science University
Postoperative Pain, Postoperative Nausea
Autonomic Neural Field Block for Visceral Pain in Minimally Invasive Left-Sided Colectomy
Effective postoperative pain control is a core component of enhanced recovery after surgery (ERAS) pathways in colorectal surgery; however, postoperative pain following minimally invasive left-sided colectomy remains a persistent…
- Conditions
- Postoperative Pain, Postoperative Nausea, Opioid Use
- Trial name
- ANfiELD (NCT07351994)
- Testing
- Autonomic Neural Field Block
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Antonio Caycedo, MD
Pain, Postoperative
The Effect of Pre-sacral Nerve Block on Immediate Post-operative Pain Following Laparoscopic Hysterectomy.
Hysterectomy (removal of the uterus) is the most common major gynecologic surgery performed in Canada. With a focus on minimally invasive techniques and optimization of peri-operative pain control, gynaecologists have made great…
- Trial name
- NCT03646006
- Testing
- Bupivacaine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Mount Sinai Hospital, Canada
Post-operative Pain
Reduction of Pain Following Laparoscopic Surgery: A Double Blind Prospective Randomized Controlled Trial
Shoulder tip and abdominal pain following laparoscopic procedures are well recognized as causes of post-operative morbidity. This prospective, double-blind, randomized controlled trial attempts to reduce post-operative pain in…
- Trial name
- NCT01720433
- Testing
- intervention
- Where
- United Kingdom
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Northampton General Hospital NHS Trust
Post Operative Pain
Study to Compare Reduction in Pain After Surgery With and Without Local Anesthesia During Laparoscopy
This study will help to answer the question, "Does injecting local anesthetic before laparoscopic instrument ports are placed decrease pain after surgery?" Patients participating will be randomly assigned to receive local…
- Trial name
- NCT01452633
- Testing
- 0.25% bupivicaine will be injected at the study port site prior to incision, Saline will be injected at the study port site prior to incision, Saline will be in injected into the port site prior to closure
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Postoperative Pain, Orthognathic Surgery
Pre-Extubation Bupivacaine for Pain Control After Orthognathic Surgery
This study aims to evaluate whether injecting a long-acting local anesthetic (bupivacaine) at surgical sites before awakening from anesthesia can reduce pain and the need for opioid medications after orthognathic surgery.
- Trial name
- NCT07518225
- Testing
- Bupivacaine Infiltration, Standard medical treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Esra Beyler
Gallstone
Study of the Use of Humidified Warmed Gas and the Effect on Post-Operative Pain in Laparoscopic Cholecystectomies
Double blind RCT comparing elective laparoscopic cholecystectomy using warmed, humidified gas (new) against laparoscopic cholecystectomy with cool, dry gas (usual). Sample size of 200 patients.
- Trial name
- NCT00792389
- Testing
- Warm humidified C02, Cool dry C02
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Pennine Acute Hospitals NHS Trust
Post Operative Pain
Superior Trunk Block Applied for Upper Arm Surgery
Nerve blocks applied with ultrasonography are currently used for many post-operative pain and operations. Providing adequate area analgesia is the primary goal of clinicians, as early mobilization is suggested after shoulder and…
- Trial name
- NCT05474014
- Testing
- superior trunk block, intravenous patient-controlled analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Breast, Mastectomy, Segmental
Post-Breast Procedure Pain Syndrome Study
The purpose of this study is to better understand and characterize the pain that some patients experience after undergoing various breast surgeries, including breast biopsy, lumpectomy, mastectomy, mastectomy with reconstruction…
- Trial name
- NCT01114984
- Where
- United States
- Sponsor
- Cedars-Sinai Medical Center
Post Operative Analgesia
Tibial Nerve Versus Sciatic Nerve Block
The purpose of this study is to analyse the ability to selectively block the posterior tibial nerve sparing the function of the common peritoneal nerve.
- Trial name
- NCT01415193
- Testing
- Selective Tibial Nerve block, Sciatic Nerve Block
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Trinity Health Of New England
Post-operative Pain, Acute
Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Post-operative Pain Relief and Decrease Opioid Consumption: a Prospective Randomized Controlled Trial
The purpose of this study is to determine whether the addition of magnesium to bupivacaine for the post-operative adductor canal blocks (ACB) can decrease opioid consumption and improve pain management for patients after same-day…
- Trial name
- NCT05004636
- Testing
- Adding Magnesium as an adjuvant to the adductor canal Block (ACB) for same-day discharge total knee arthroplasty
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Wayne State University
Post Operative Pain, Acute, Bariatric Surgery Candidate
ZYNRELEF® for Postoperative Analgesia After Laparoscopic Sleeve Gastrectomy
Approximately 120 subjects will be randomized into 1 of the following 2 treatment groups in a 1:1 ratio: Group 1: ZYNRELEF® up to 200 mg/ 6mg ( 7ml vial) via instillation at all incision sites in addition to 30 ml of 0.5%…
- Conditions
- Post Operative Pain, Acute, Bariatric Surgery Candidate, Postoperative Pain
- Trial name
- HeronBariatric (NCT05863221)
- Testing
- ZYNRELEF 200Mg-6Mg Extended-Release Solution
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Dr. Yannis Raftopoulos
Pain
Ultrasound-guided Rectus Sheath Block for Post-operative Pain Control Following Umbilical Hernia Repair
The purpose of this study is to compare the effectiveness of local infiltration to an ultrasound guided nerve block placed by the anesthesiologist for children undergoing umbilical hernia repair.
- Trial name
- NCT00836134
- Testing
- rectus sheath block, local anesthetic infiltration
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Seattle Children's Hospital
Supratentorial Neoplasms
Pre- vs. Postoperative Scalp Block for Pain Control After Supratentorial Craniotomy
Study was designed to evaluate optimal timing for selective scalp block in patients undergoing general anesthesia for supratentorial craniotomy.Pain score assessed by visual analog scale (VAS) preoperatively (baseline) and after…
- Trial name
- NCT04344132
- Testing
- Scalp Block
- Volunteers
- 50 people
- Sponsor
- University of Roma La Sapienza
Opioid Analgesia
Pharmacokinetics and Safety of ORF Tablets in Pediatric Patients
The purpose of this study is to characterize the pharmacokinetics (PK) of single-dose ORF tablets in pediatric patients aged 6 to 16 years, inclusive.
- Trial name
- NCT01160614
- Testing
- Oxycodone hydrochloride controlled-release (ORF) tablets
- Where
- 17 sites in United States, Australia and 2 more
- Volunteers
- 30 people
- Sponsor
- Purdue Pharma LP
Post-operative Pain
Oral vs Intravenous Acetominophen for Postoperative Pain in Minimally Invasive Gynecologic Surgery
Hypothesis: Postoperative pain will be equivalent in patients receiving preemptive oral acetaminophen as compared to patients receiving preemptive intravenous acetaminophen following minimally invasive benign gynecologic surgery.
- Trial name
- NCT03391284
- Testing
- acetominophen, Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Scripps Health
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