Clinical trials: Post-operative Pain Control
Inguinal Hernia
Effect of Ultra-Sound Guided Pre-emptive Nerve Block on Post-operative Pain Following Open Inguinal Hernia Repair.
A hernia occurs when an organ 'like intestines' or fatty tissue protrude through a weak point in muscle or connective tissue and one of the most common types of hernia is inguinal.
- Trial name
- NCT04792164
- Testing
- Ultra sound guided nerve block, Usual infiltration
- Volunteers
- 136 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Postoperative Pain, Bariatric Surgery Candidate
Intravenous Ibuprofen Versus Ketorolac in Bariatric Surgery
The aim of the current study is to compare the analgesic effects of both drugs in patients with obesity undergoing bariatric surgery.
- Trial name
- NCT05801900
- Testing
- Ketorolac group, Ibuprofen group
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Cairo University
Post Operative Analgesia
Erector Spinae Catheter for Open Heart Surgery
Fast track to Extubation after cardiothoracic surgery is becoming more common after a number of reports showing it is safe and effective. However, It has introduced new challenges to pain control.
- Trial name
- ESPADULT2 (NCT03901612)
- Testing
- Ropivacaine 0.2%, saline 09%
- Where
- Vietnam
- Sponsor
- Vinmec Healthcare System
Pain, Decreased Lung Function
ThOracoscopic Wedge Resection Treated With Chest Tube Removal Intraoperatively
Chest tubes are used routinely although preliminary studies demonstrate the feasibility and safety of intraoperative chest drain removal. Previous studies are however either retrospective or mainly concerning benign disease.
- Conditions
- Pain, Decreased Lung Function, Delayed Discharge
- Trial name
- TOTTI (NCT02829736)
- Testing
- Intraoperative sealing test, Standard post-operative chest tube, Intraoperative chest tube removal
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Dental Pulp Necroses, Apical Periodontitis
Effects of Intracanal Cryotherapy on Endodontic Postoperative Pain
The goal of this clinical trial is to evaluate the effect of cold saline (2.5 degrees Celsius) irrigation on postoperative pain in patients who require root canal treatment in molar teeth because of dead dental pulp and infection…
- Conditions
- Dental Pulp Necroses, Apical Periodontitis, Post Operative Pain
- Trial name
- NCT05611736
- Testing
- cold saline, saline
- Where
- Saudi Arabia
- Volunteers
- 302 people
- Sponsor
- Qassim University
Postoperative Pain, Narcotic Use
Novel Multimodal Pain Control Protocol for Minimally Invasive Gynecologic Surgery
The study is a randomized controlled trial investigating a multimodal postoperative pain management protocol which will include use of ice therapy and scheduled opioid-sparing medications for pain control after minimally invasive…
- Conditions
- Postoperative Pain, Narcotic Use, Cryotherapy Effect
- Trial name
- NCT04710277
- Testing
- Opioid-sparing multimodal pain management, Usual care
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Pain, Postoperative
Erector Spinae Block Versus Thoracic Paravertebral Block for Postoperative Pain Control After Open Nephrectomy
the study aims to compare the analgesic efficacy of erector spinae plane block versus thoracic paravertebral block after open nephrectomy surgery.
- Trial name
- NCT04719507
- Testing
- erector spinae block, thoracic paravertebral block, Pethidine Only Product in Parenteral Dose Form
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lung Cancer, Pain, Postoperative
Pain Control After VATS Anatomical Pulmonary Resections
In patients undergoing minimally invasive thoracoscopic surgery (video-assisted thoracoscopic surgery, or VATS), moderate to severe post-operative pain may often be experienced.
- Conditions
- Lung Cancer, Pain, Postoperative, Thoracic Neoplasms
- Trial name
- NCT05993273
- Testing
- Epidural, ESP block, Cryoanalgesia
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- University Hospital Padova
Post Operative Pain, Impacted Third Molar Tooth
Pain Control Following Third Molar Surgery
In this study, the investigators recruited patients undergoing surgical removal of impacted third molar teeth. Participants will be randomly divided into two groups Group 1: The patient will receive 400mg of ibuprofen plus 1000mg…
- Trial name
- NCT06514222
- Testing
- Paracetamol and Ibuprofen. The combination of the Paracetamol and Ibuprofen will be given together every 8 hours, Paracetamol and Ibuprofen. The combination of the Paracetamol and Ibuprofen will be given alternatively every four hours
- Where
- United Arab Emirates
- Volunteers
- 56 people
- Sponsor
- University of Sharjah
Neuropathic Pain
The Significance of Peripheral Input
The investigators want to examine trigger point injections of local anesthetics, in patients with post operative neuropathic pain, determine changes in sensory disturbances such as allodynia, hyperalgesia and thermal sensitivity…
- Trial name
- NCT04764045
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Bispebjerg Hospital
Post Operative, Post Operative Analgesia
Postoperative Tizanidine Use in Pelvic Reconstructive Surgery: A Pilot Study
The goal of this clinical trial is to evaluate whether adding tizanidine to the standard postoperative pain regimen improves recovery after pelvic reconstructive surgery in adult women.
- Conditions
- Post Operative, Post Operative Analgesia, Urogynecologic Surgery
- Trial name
- TIPS (NCT07766837)
- Testing
- Tizanidine, Standard-of-Care Therapy
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Hartford Hospital
Pain Management
Comparing the Effectiveness of Hyalone and Calcium Hydroxide in Reducing Post-operative Pain and Promoting Periapical Healing.
This protocol presents a randomized clinical trial comparing Hyalone (hyaluronic acid) with calcium hydroxide as intracanal medicaments in mandibular first molars with necrotic pulp and symptomatic apical periodontitis.
- Trial name
- HCPH (NCT07821866)
- Testing
- Hyalone, Calcium Hydroxide (Ca(OH)2) Intracanal Medication
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Cesarean Section Post Operative Management
The Use of Abdominal Binders in Patients Undergoing Cesarean Sections
To see if the use of Abdominal Binders improves patients out comes after cesarean delivery
- Trial name
- NCT02129894
- Testing
- abdominal Binder
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- St. Luke's Hospital, Pennsylvania
Heated Humidified Carbon Dioxide in Gynaecological Laparoscopic Surgery
Standard Carbon Dioxide Gas Versus Heated Humidified Gas in Gynaecological Laparoscopy
To establish if heated humidified carbon dioxide gas improves pain scores as well as nausea and analgesic requirements in post operative patients compared to standard cold carbon dioxide.
- Trial name
- NCT02319902
- Testing
- Standard cold carbon dioxide gas, Heated humidified carbon dioxide gas
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fevzi Shakir
Breast Cancer, Postoperative Pain
Comparison of Pre-op and Post-op Pectoralis Nerve Block
The investigators will compare whether patients will have better pain control if they were to receive (PEC I/II block) before surgery or after mastectomy.
- Conditions
- Breast Cancer, Postoperative Pain, Anesthesia, Nerve Block
- Trial name
- NCT03653988
- Testing
- PEC I/II blocks by anesthesiologist - pre-operative, PEC I/II blocks by surgeon - intra-operative
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Melinda Seering
Chronic Pain, Opioid Use
Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty
The goal of this interventional clinical trial is to assess opioid consumption 24-48 hrs post anesthesia block among patients undergoing total knee arthroplasty. The main question it aims to answer is: 1.
- Conditions
- Chronic Pain, Opioid Use, Adductor Canal Block, Total Knee Arthroplasty
- Trial name
- NCT05981105
- Testing
- ambIT pump with catheter
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Hospital for Special Surgery, New York
Pain, Postoperative
Popliteal Nerve Block for Postoperative Pain Control in Ankle and Hindfoot Reconstruction
The purpose of this study is to evaluate outcomes of popliteal nerve blocks for postoperative pain control in patients undergoing ankle and hindfoot reconstruction surgeries.
- Trial name
- NCT02440542
- Testing
- Survey of outcomes following popliteal nerve block
- Sponsor
- University of Tennessee
Post-Operative Pain
Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty.
The purpose of this phase 2 study is to evaluate the efficacy and safety of an analgesic drug candidate, VVZ-149 Injections. The study is designed as randomized, double-blind, parallel, and placebo-controlled study.
- Trial name
- NCT03347266
- Testing
- VVZ-149 injections
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Vivozon, Inc.
Total Knee Arthroplasty
Single-injection Adductor Canal Block for Total Knee Arthroplasty Under Spinal Anesthesia
This study evaluates the effect of the single-injection adductor canal block in patients receiving total knee arthroplasty under spinal anesthesia.
- Trial name
- NCT04400708
- Testing
- adductor canal block, control group
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Post-operative Pain, Thoracic Epidural
Dexmedetomidine and Fentanyl as Adjuvants to Thoracic Epidural
To find out if there is a benefit from adding dexmedetomidine to epidural bupivacaine as regards: Intra and postoperative opioid consumption Pain score (numerical rating scale) Hemodynamic stability, Patient satisfaction.
- Conditions
- Post-operative Pain, Thoracic Epidural, Thoracotomy Surgery
- Trial name
- adjuvants (NCT06489574)
- Testing
- thoracic epidural with dexmedetomidine in patients undergoing thoracotomy surgery, thoracic epidural with fentanyl in patients undergoing thoracotomy surgery
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
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