Clinical trials: Post-operative Pain Control
Pain, Chronic Postsurgical, Knee Osteoarthritis
Central Sensitization in Total Knee Arthroplasty Patients with Persistent Pain
Persistent post-surgical pain is a significant adverse effect after total knee arthroplasty, present in around 20% of the patients. Central sensitization may contribute to developing and maintaining pain.
- Conditions
- Pain, Chronic Postsurgical, Knee Osteoarthritis, Sensitization, Central
- Trial name
- NCT05575310
- Testing
- Total Knee Arthroplasty
- Where
- Spain
- Volunteers
- 117 people
- Sponsor
- University of Barcelona
Anterior Cruciate Ligament Rupture
Adductor Canal Block and IPACK Block vs. Isolated Adductor Canal Block for Post-Operative Analgesia Following ACL Reconstruction With Bone Patellar Tendon Bone Autograft:
A randomized, single-blind, single-center study measuring the effects of adductor canal block combined with IPACK infiltration compared to adductor canal block alone on post-operative pain and opioid consumption in patients…
- Trial name
- NCT05286307
- Testing
- IPACK block
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- NYU Langone Health
Pain, Postoperative, Analgesia
IV Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy
This double-blinded, placebo-control trial clinical trial aims to investigate the effect of IV oxytocin infusion on peri-operative opioid consumption following a minimally invasive hysterectomy under general anesthesia.
- Conditions
- Pain, Postoperative, Analgesia, Postoperative Pain, Pain, Post Operative
- Trial name
- NCT05608070
- Testing
- Oxytocin
- Sponsor
- Beth Israel Deaconess Medical Center
Endometriosis, Post Operative Pain
The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study
This is a randomized, single blinded, placebo-controlled trial to study the effectiveness of a subanesthetic dose (0.6 mg/kg) of ketamine versus placebo (saline) on postoperative pain and pain on adult female chronic pelvic pain…
- Trial name
- NCT05229653
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- NYU Langone Health
Pain, Postoperative
US-guided Ilioinguinal Blocks Versus Local Infiltration
Injection of local anesthetic drugs is an effective way to freeze (block) nerves to achieve loss of sensation during surgery and satisfactory pain control afterwards.
- Trial name
- NCT01871181
- Testing
- Ilioinguinal block, Local infiltration
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Postoperative Pain
Lumbar Plexus Catheter Versus Femoral Nerve Catheter for Postoperative Pain After Anterior Cruciate Ligament (ACL) Repair
Randomized trial comparing lumbar plexus catheter versus femoral nerve catheter (single-shot femoral block as control group) for postoperative pain control after anterior cruciate ligament repair in children (age 11-21).
- Trial name
- NCT01068275
- Testing
- lumbar plexus catheter, femoral nerve catheter, single-shot femoral block
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Seattle Children's Hospital
Pain, Postoperative
Preemptive Analgesia With Celecoxib for Acute Dental Pain Management
The purpose of this study is to compare the effect on postoperative pain of a single agent nonsteroidal anti-inflammatory drug (NSAID) [celecoxib plus placebo] to an NSAID combination [celecoxib plus acetaminophen] administered…
- Trial name
- NCT04790812
- Testing
- Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Peripheral Nerve Block, Post Operative Analgesia
Transversus Abdominis Plane Lock Versus Quadratus Lumborum Block in Children
Although abdominal wall surgeries are also as routinely performed on pediatric patients, postoperative pain in children has remained under-researched compared to adults.
- Conditions
- Peripheral Nerve Block, Post Operative Analgesia, Ultrasound-guided Regional Anesthesia
- Trial name
- NCT06861556
- Testing
- Ultrasound guided Transversus Abdominis Plane block with 0.2ml/kg bupivacaine 0.25%, Ultrasound-guided Quadratus Lumborum block with 0.2ml/kg bupivacaine 0.25%
- Where
- Tunisia
- Volunteers
- 90 people
- Sponsor
- Tunis University
Pain, Postoperative
Effect of Bilateral Erector Spinae Plan Block in Colorectal Surgery
In this study, it was aimed to evaluate the effects erector spina plane block (ESPB) on postoperative opioid consumption in the first 24 hours and pain scores after colorectal surgery.
- Trial name
- NCT05256953
- Testing
- Erector spina plane block + general anesthesia, Only general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Total Knee Replacement
Analgesic Efficacy of Pre-Operative Dose of Palmitoylethanolamide in Patients Undergoing Total Knee Arthroplasty
Analgesic Efficacy of Pre-Operative Dose of palmitoylethanolamide in Patients Undergoing total Knee Arthroplasty, A Randomized Double-Blinded Controlled Trial.
- Trial name
- Total knee (NCT07330765)
- Testing
- Effect of two different drugs on post operative pain after TKA
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Abdelrahman Gaber Sayed Elkhateeb
Post Operative Pain
Methadone in TKA for Post-op Pain and Opioid Reduction
This randomized, double-blind controlled trial investigates whether intraoperative IV methadone (0.15 mg/kg based on ideal body weight) reduces acute postoperative pain and opioid consumption in patients undergoing elective total…
- Trial name
- NCT07226076
- Testing
- Methadone Hydrochloride
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Medical University of South Carolina
Tonsillectomy
Celecoxib After Tonsillectomy
Tonsillectomy is one of the most common pediatric surgical procedures in the United States. Postoperative pain is substantial, with typical regimens employing narcotic derivatives and acetaminophen for 1-2 weeks after surgery.
- Trial name
- NCT02934191
- Testing
- Celecoxib, Acetaminophen, Oxycodone
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Children's Hospital of Philadelphia
Postoperative Pain
Effect of Local Anesthetic Infiltration for Postoperative Pain Control in Laparoscopic Abdominal Surgery: A Prospective Randomized Study
Brief Summary Postoperative pain remains a common problem after laparoscopic abdominal surgery despite the minimally invasive nature of these procedures.
- Trial name
- NCT07747584
- Testing
- Bupivacaine, Standard Perioperative Analgesia
- Where
- Pakistan
- Volunteers
- 166 people
- Sponsor
- Allied Hospital Faisalabad
Orthopaedics Wound Dressings
Comparative Efficacy of Advanced and Traditional Wound Dressings in Post-Operative Orthopedic Care
Title: Comparative Efficacy of Advanced and Traditional Wound Dressings in Post-Operative Orthopedic Care: A Randomized Controlled Trial Objective: The primary objective of this study is to evaluate and compare the efficacy of…
- Trial name
- NCT06540040
- Testing
- Aquacel Ag, OPSITE, MEPILEX POST OP BORDER
- Where
- India
- Volunteers
- 320 people
- Sponsor
- Nidhi Srivastava
Kidney Stones
Dual Approach External Oblique Fascial Plane Block Versus Erector Spinae Plane Block for Post Operative Analgesia in Percutaneous Nephrolithotomy
Here is a patient-friendly, ClinicalTrials.gov-compliant Brief Summary written in plain language, avoiding technical jargon as much as possible while remaining accurate.
- Trial name
- BLOCK-PCNL (NCT07359391)
- Testing
- Erector Spinae Plane Block, Dual External Oblique Fascial Plane Block, General Anesthesia
- Volunteers
- 90 people
- Sponsor
- Zagazig University
Pain, Postoperative
Comparative Evaluation of Two Different Post-Operative Analgesia After Hallux Valgus Correction
Background: Recent studies showed the efficiency of several techniques of anesthesia in foot surgery. The new mini-invasive surgical approaches should require less analgesia and rapid motor recovery after surgery.
- Trial name
- NCT03396991
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pain, Postoperative
Analgesic Efficacy of Repeated Doses of Intravenous (IV) Acetaminophen in Post-operative Pediatric Spine Fusion Patients
This is a prospective, randomized, double-blinded, placebo controlled trial Potential subjects will be identified from the Pre-Surgical Anesthesia Clinic visit.
- Trial name
- IV APAP SF (NCT01394718)
- Testing
- Intravenous Acetaminophen
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Children's Hospital of Philadelphia
Pain, Postoperative, Fractures, Open
Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Pilot
Psychological factors such as stress, distress, anxiety, depression, and poor coping strategies may be associated with ongoing pain following injuries such as fractures.
- Conditions
- Pain, Postoperative, Fractures, Open, Fractures, Closed
- Trial name
- COPE Pilot (NCT03673358)
- Testing
- Cognitive Behavioural Therapy
- Where
- 6 sites in Canada
- Volunteers
- 83 people
- Sponsor
- McMaster University
Post Operative Analgesia
Interest of Continuous Ropivacaine Administration Through an Elastomeric Pump (Pain Buster) for the Surgery of Latissimus Dorsi and Serratus Micro Anastomotic Flaps
Continuous bupivacaine administration through an elastomeric pump (Pain Buster) has been found effective for post operative analgesia in a large range of surgery.
- Trial name
- NCT00724685
- Testing
- Naropeine (Ropivacaine)
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Nantes University Hospital
Arthroplasty, Replacement, Knee, Pain, Postoperative
Pharmacogenomics Information in Enhancing Post-operative Total Joint Replacement Pain Management: a Pilot Study
The objective of this study is to see how pain management and its outcomes are effected when pharmacogenomic testing is used to determine patient specific pain medication and dosing.
- Trial name
- NCT02711592
- Testing
- Genetic Panel for Analgesics
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- TriHealth Inc.
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