Clinical trials: Post-operative Pain Control
Pain, Postoperative Period
Ketamine Combination With Spinal Morphine for Post Thoracic Surgery Pain : A Randomized Control Study
Thoracotomy is one of the most painful operation. Continuous thoracic epidural or paravertebral analgesia are gold standard for postoperative pain. But both techniques require skills.
- Trial name
- NCT02570230
- Testing
- NSS, Ketamine
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Mahidol University
Post Operative Pain
Comparison of Postoperative Pain After Root Canal Treatment With Rotary vs Reciprocating Systems
To compare the postoperative pain in patients undergoing root canal instrumentation with two different file systems, Hyflex EDM and Reciproc VDW.
- Trial name
- Post op pain (NCT06779565)
- Testing
- Hyflex EDM system, Reciproc VDW system
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Hip Fractures, Post Operative Pain
Comparison Between Bupivacaine-Dexmedetomidine Versus Bupivacaine-Dexamethasone in Pericapsular Nerve Group (PENG) Block
The aim of this work is to compare the effectiveness of bupivacaine- dexmedetomidine mixture versus bupivacaine-dexamethasone mixture in PENG Block as Post-operative Analgesia in Hip surgeries
- Trial name
- NCT06294665
- Testing
- Pericapsular Nerve Group (PENG) Block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Patellar Denervation, Non-patellar Denervation
Comparative Study Between Patellar Denervation and Non-patellar Denervation in Total Knee Arthroplasty With Patellar Resurfacing
The purpose of this study is to compare the post-operative anterior knee pain (AKP) between patellar denervation and non-patellar denervation in total knee arthroplasty with patellar resurfacing
- Conditions
- Patellar Denervation, Non-patellar Denervation, Patellar Resurfacing
- Trial name
- NCT03389880
- Testing
- Total knee arthroplasty, Patellar denervation
- Where
- Thailand
- Volunteers
- 241 people
- Sponsor
- Navamindradhiraj University
Anesthesia, Shoulder Pain
Dexmedetomidine Added to Ropivacaine Single Shot vs Continuous Interscalene Nerve Block
Arthroscopic shoulder surgery is increasingly performed in an outpatient setting and post-operative pain management is often a real challenge as those surgeries are well recognized for their high level of pain which often affects…
- Conditions
- Anesthesia, Shoulder Pain, Post Operative Pain
- Trial name
- DEXBIB (NCT05775861)
- Testing
- single shot interscalene brachial plexus block group with dexmedetomidine added to ropivacaine group, continuous interscalene brachial plexus block
- Where
- Canada
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Ventral Hernia, Incisional Hernia
Randomized Control Trial Comparing Transfascial Suture for Mesh Fixation to No Mesh Fixation
This will be a single blinded, registry based, non-inferiority, randomized control trial comparing transfacial sutures for mesh fixation to no mesh fixation in open retromuscular repairs.
- Trial name
- NCT03938688
- Testing
- Mesh placement with Transfascial Sutures
- Where
- United States
- Volunteers
- 325 people
- Sponsor
- The Cleveland Clinic
Pulp Disease, Dental
Effect of Cavity Disinfectants on Post Operative Pain & Success of Partial Caries Removal
To investigate The Effect of Sodium hypochlorite and Chlorhexidine as cavity Disinfectants on the post operative pain and Success of Partial Caries Removal in deep carious lesion with moderate pulpitis in permanent teeth
- Trial name
- NCT06836882
- Testing
- Selective caries removal, Selective caries removal with NaOCl, Selective caries removal with CHX
- Where
- India
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Laparoscopic Cholecystectomy, Postoperative Pain
RIPB Versus EOIPB for Pain Control After Laparoscopic Cholecystectomy
This prospective observational study aims to compare the effects of bilateral ultrasound-guided recto-intercostal plane block(RIPB) and bilateral ultrasound-guided external oblique intercostal plane block(EOIPB) on postoperative…
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Pain, Postoperative Analgesia
- Trial name
- RIPB-EOIPB (NCT07607262)
- Testing
- Bilateral Ultrasound-Guided Recto-Intercostal Plane Block, Bilateral Ultrasound-Guided External Oblique Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Breast Cancer, Postoperative Pain
Comparison of Pre-op and Post-op Pectoralis Nerve Block
The investigators will compare whether patients will have better pain control if they were to receive (PEC I/II block) before surgery or after mastectomy.
- Conditions
- Breast Cancer, Postoperative Pain, Anesthesia, Nerve Block
- Trial name
- NCT03653988
- Testing
- PEC I/II blocks by anesthesiologist - pre-operative, PEC I/II blocks by surgeon - intra-operative
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Melinda Seering
Laparoscopic Cholecystectomy
Transdermal Buprenorphine Patch for Laparoscopic Cholecystectomy
Preliminary studies of the transdermal buprenorphine patch target chronic pain patients, and the pain relief effect and safety have been proven.
- Trial name
- NCT05871424
- Testing
- buprenorphine patch group
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Gangnam Severance Hospital
Postoperative Pain, Acute
Effect of Transcutaneous Vagus Nerve Stimulation for Pain Control After Cesarean Delivery
This study investigates whether non-invasive transcutaneous auricular vagus nerve stimulation can alleviate postoperative pain in patients after cesarean section, and explores its possible mechanisms of action through an…
- Trial name
- NCT06788561
- Testing
- Transauricular Nerve Stimulation, s-taVNS
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Beijing Tongren Hospital
Total Knee Arthroplasty, Post-operative Pain Control
Adductor Canal Block Versus Liposomal Bupivacaine in TKA
This is a randomized prospective study of 60 patients undergoing total knee arthroplasty evaluating the clinical outcomes of liposomal bupivacaine periarticular injections (PAI) when compared to single shot adductor canal block…
- Trial name
- NCT04086186
- Testing
- Liposomal Bupivacaine Peri-articular Injection, Adductor canal block
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Good Samaritan Regional Medical Center, Oregon
Post Operative Pain
Pre-incision Versus Lapaorscopic-assisted Transversus Abdominis Plane (TAP) and Rectus Sheath Block for Post-Cholecystectomy Pain
The goal of this clinical trial is to compare pre-incision vs laparoscopic assisted Transversus abdominis plane and rectus sheath block in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT05856682
- Testing
- Laparoscopic-assisted TAP block(LATAP) and Rectus Sheath block
- Where
- Pakistan
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Patel Hospital, Pakistan
Pain, Postoperative
Non-pharmacological Methods for the Control of Anxiety and Pain During Outpatient Hysteroscopy
The administration of pharmacological and non-pharmacological aids during in-office hysteroscopic surgery is often used to both relieve the patient from discomfort and facilitate the operator in performing the procedure.
- Trial name
- NCT05700123
- Testing
- In-Office Hysteroscopy
- Where
- 3 sites in Italy
- Volunteers
- 198 people
- Sponsor
- University of Campania Luigi Vanvitelli
Spinal Anesthesia, Post Operative Analgesia
Dexamethasone in Prolonging the Duration of Spinal Anesthesia Among Pregnant Patients
Lower segment C section is one of the most commonly performed surgeries worldwide. It is performed in spinal anesthesia. During Spinal Anesthesia a local anesthetic drug is administered in a space surrounding spinal cord and it…
- Trial name
- NCT07088146
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified
Cyclobenzaprine for Postoperative Pain in Minimally Invasive Hysterectomy
Typical postoperative pain control after minimally invasive hysterectomy includes ibuprofen, acetaminophen, and a short course of narcotics.
- Conditions
- Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified, Adenomyosis of Uterus, Fibroid Uterus
- Trial name
- NCT07664956
- Testing
- Cyclobenzaprine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Christiana Care Health Services
Pregnancy
Comparative Study of Ropivacaine and Ropivacaine With Dexmeditomedine in TAP Blocks
Comparative study of Ropivacaine and Ropivacaine with dexmedetomidine in transversus abdominis plane (TAP) block for post-operative analgesia in patients undergoing Caesarean Section.
- Trial name
- NCT02472522
- Testing
- Ropivacaine + Dexmedetomidine, Ropivacaine
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Tata Main Hospital
Breast Neoplasm
The Effects of Perioperative PECS Block During Robotic Breast Surgery and Breast Reconstruction
Pectoral nerve blocks (PECS blok) are used in postoperative analgesia after breast surgery in nowadays. Many studies shows that pectoral nerve blocks is effective for reducing pain and postoperative opioid consumption undergoing…
- Trial name
- NCT04440995
- Testing
- pectoral nerve block
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Post Operative Pain Control
Effect of a Multimodal Pain Regimen on Pain Control, Patient Satisfaction and Narcotic Use in Orthopaedic Trauma Patients
The study is a prospective, randomized, open-label comparison of a multimodal regimen and a standard, narcotic-based regimen for postoperative pain control in patients undergoing surgery for an operatively indicated, isolated…
- Trial name
- NCT02160301
- Testing
- Gabapentin, Acetaminophen, Celecoxib
- Where
- United States
- Sponsor
- University of North Carolina, Chapel Hill
Prostate Cancer
Qudratus Lumborum Block for Postoperative Pain After Endoscopic Prostatectomy.
Laparoscopic prostatectomy (LP) is characterized by substantial tissue trauma, despite its minimally -invasive approach. Although postoperative pain intensity is lower when compared to open procedures, the use of opioids is…
- Trial name
- NCT03600129
- Testing
- Qadratus Lumborum Block, 30 milliliters of 0.375% Ropivacaine, 30 milliliters of 0.9% NaCl
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Centre of Postgraduate Medical Education
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