Clinical trials: Post-operative Pain Control
Pain, Postoperative
Loco-regional Analgesia for Post-operative Pain Management in Cardiac Surgery
The aim of the study is to evaluate whether loco-regional analgesia reduces post operative pain compared to intravenous analgesia, in patients undergoing cardiac surgery in minithoracotomy.
- Trial name
- NCT01903551
- Testing
- Loco-regional catheter
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- University of Turin, Italy
Pain, Postoperative
Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
The purpose of this study is to evaluate the patient experience when using gabapentin with other pain control medications after posterior spinal fusion surgery for scoliosis in adolescents.
- Trial name
- NCT01977937
- Testing
- Gabapentin 250mg/5mL NDC:59762-5025-01, Simple Syrup
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Oregon Health and Science University
Post Operative Pain Control, PONV
Effectiveness of Unilateral Transversus Abdominis Plane (TAP) Block vs Bilateral TAP Block in Patients Undergoing Laparoscopic Cholecystectomy.
In this study, patients undergoing laparoscopic cholecystectomy will be randomly divided into 2 groups after consent. Group A patients will be administered a one-sided (right unilateral) regional TAP block and group B patients…
- Trial name
- NCT07513012
- Testing
- Unilateral Transversus abdominis plane (TAP) block with 0.25 % bupivacaine, Bilateral Transversus abdominis plane (TAP) block with 0.25 % bupivacaine
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- King Edward Medical University
Postoperative Pain, Postoperative Complications
Rebound Pain and Related Factors in Postoperative Patients With Total Knee Arthroplasty
The aim of this prospective observational study is to detect rebound pain and related factors in postoperative patients with total knee arthroplasty.
- Conditions
- Postoperative Pain, Postoperative Complications, Postoperative Nausea and Vomiting
- Trial name
- NCT05910281
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Gulhane Training and Research Hospital
Patients Undergoing a Lumbar Slipped Disc Surgery
Co-analgesic Effects of Dexamethasone and Pregabalin After Lumbar Slipped Disc Surgery
The aim of the study is to show a decrease in postoperative pain during the first postoperative mobilization surgery lumbar disc herniation through a co-analgesia with a single dose of dexamethasone, pregabalin, or a combination…
- Trial name
- DEXA-PG-HD (NCT01811251)
- Testing
- Pregabaline (150mg), Dexamethasone (20mg/5ml; 0.2mg/kg)
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Clermont-Ferrand
Inguinal Hernia
Comparison of Analgesic Effect of Magnesium Added to Ropivacaine and Ropivacaine Alone in Caudal Analgesia on Postoperative Pain Control in Pediatric Patients Undergoing Inguinal Hernia Repair
A caudal anesthesia is one of the most commonly used technique providing intra and postoperative analgesia in pediatric low abdominal surgery.
- Trial name
- NCT01679353
- Testing
- caudal block, normal saline 0.5ml
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University
Analgesia, Epidural
TAP vs Caudal Block Using Dexmedetomidine/ Bupivacaine for Post Operative Analgesia
Caudal epidural block is a well-established and commonly performed regional neuraxial technique for providing intraoperative and postoperative analgesia in children scheduled for lower abdomen/perineal surgical interventions.
- Trial name
- NCT03482947
- Testing
- ultrasonography-guided TAP block, Caudal epidural block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Inguinal Hernia Unilateral
Comparison of Mean Duration of Post Operative Analgesia Following QL-2 Block vs QL-3 Block Using Ropivacain 0.25% in Patients Undergoing Unilateral Inguinal Hernia Repair
To compare the mean dulation of post operative analgesia following QL2 block (posterior quadratus lumborum block) and the QL3 block (transmuscular quadratus lumborum block) using ropivacaine 0.25% in patients undergoing…
- Trial name
- NCT07200076
- Testing
- Quadratus Lumborum (QL) Block
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Quaid-e-Azam Medical College
Cesarean Birth, Post Operative Analgesia
The Effect of Lactoferrin on Pain Management Following Cesarean Section
This study evaluates whether lactoferrin, a naturally occurring protein with anti-inflammatory and antioxidant properties, can improve pain control after cesarean section.
- Trial name
- NCT07502235
- Testing
- Lactoferrin
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Post Operative Pain
Analgesic Effect of M-TAPA on LC
Objective: To investigate the postoperative analgesic efficacy of M-TAPA block and its effect on opioid consumption in patients undergoing laparoscopic cholecystectomy (LC) surgery.
- Trial name
- NCT05891652
- Testing
- modified thoracoabdominal nerve block through perichondrial approach
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Cumhuriyet University
Pain
Lidocaine For Treatment of Post-operative Pain From Donor Sites Following Burn Injury.
Burn pain is known to be one the most severe forms of acute pain often requiring large amounts of narcotics in addition to other adjuvants.
- Trial name
- LidocaineBurn (NCT02229578)
- Testing
- Lidocaine
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pain, Postoperative Pain
Efficacy of Different Drugs to Control Post Root Canal Treatment Pain
Root canal therapy will ideally eliminate post-endodontic pain but occasionally analgesics are needed to diminish the pain [Owatz et al 2007].
- Conditions
- Pain, Postoperative Pain, Irreversible Pulpitis
- Trial name
- NSAID (NCT02417337)
- Testing
- Paracetamol, Ibuprofen, Mefenamic Acid
- Where
- Sudan
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University of Khartoum
Post Operative Pain, Spinal Fusion
Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine
A randomized controlled trial (RCT) investigating whether the local anesthetic injection of liposomal bupivacaine during posterior spinal fusion (PSF) for AIS is more effective in reducing acute postoperative opioid consumption…
- Trial name
- NCT06471348
- Testing
- Bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride and Epinephrine Injection
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Boston Children's Hospital
Liver Cancer, Pain Postoperative
Parecoxib Versus Celecoxib Versus Oxycodone in Pain Control for Transcatheter Chemoembolization Procedure
This phase III, randomized, prospective clinical study, aiming to compare the analgesic effects of celecoxib, parecoxib, and oxycodone in patients with inoperable hepatic carcinoma undergoing TACE procedure in postoperative pain…
- Trial name
- NCT03059238
- Testing
- Celecoxib 200mg oral capsule, parecoxib sodium, controlled-release oxycodone
- Where
- China
- Volunteers
- 213 people
- Sponsor
- Sun Yat-sen University
Liposomal Bupivacaine
Exparel Versus Bupivacaine in Post-operative Pain Control
This is a prospective, randomized study to evaluate anaesthetic parameters, postoperative analgesia and oral analgesic consumption comparing exparel (liposomal bupivacaine) vs. standard bupivacaine
- Trial name
- NCT06547255
- Testing
- Bupivacaine liposome injectable suspension
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Post Operative Pain
Analgesic Efficacy of Genicular Nerve Block Versus (IPack Block ) in Patients Undergoing (ACL) Repair
One of the most common injuries to the knee is an anterior cruciate ligament (ACL) sprain or tear due to trauma ACL damage is crippling and often requires repair with an arthroscopic method, which is an outpatient surgery.
- Trial name
- NCT06404658
- Testing
- Genicular nerve block
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Pain, Postoperative, Osteoarthritis, Knee / Osteoarthritis, Hip
iPACK Block vs. Periarticular Infiltration for TKA Pain Control
This study aims to retrospectively compare two different multimodal analgesic techniques for pain management after total knee arthroplasty (TKA).
- Trial name
- NCT07267650
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Turgutlu State Hospital
Inguinal Surgery
Ibuprofen Compared to Morphine as a Pediatric Postoperative Pain Management Tool Following Inguinal Surgery
Morphine is now the most commonly used opioid in children for pain management even though the safety of morphine use in children is a primary concern for parents as it is perceived to have more associated risks.
- Trial name
- NCT02603848
- Testing
- Ibuprofen, Morphine
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Opioid-use Disorder
The Effect of Buprenorphine Continuation for Patients With Opioid Use Disorder
There is limited guidance on the optimal management of buprenorphine perioperatively and both buprenorphine discontinuation and continuation are acceptable standards of care.
- Trial name
- NCT04981678
- Testing
- Buprenorphine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- MaineHealth
Pain, Postoperative
The Use of Cannabidiol (CBD) in Pain Reduction and Opioid Use After Shoulder Arthroscopy
This study is designed to evaluate the effects of administering CBD to control post-operative pain in patients undergoing shoulder arthroscopy.
- Trial name
- NCT04672252
- Testing
- CBD Oral Disintegrating Tablet (ODT)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
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