Clinical trials: Post-operative Pain Control
Post Operative Pain
Rhomboid Intercostal Block Versus Retrolaminar Block for Postoperative Analgesia After Thoracoscopic Sympathectomy
Background: Although thoracoscopic sympathectomy is made via small incisions, it is associated with severe postoperative pain. Both Rhomboid intercostal block (RIB) and Retrolaminar block (RLB) are recent techniques used for pain…
- Trial name
- NCT06653803
- Testing
- Rhomboid Intercostal Block (RIB), Retrolaminar Block (RLB)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
Revision Spine Surgery, Fusion of Spine
Pre-Operative Ketamine Infusion for Post Operative Pain Control After Revision Spinal Surgery
To determine if a pre-operative ketamine infusion would provide a similar decrease in post-operative analgesic and opioid consumption as intra-operative ketamine, but expand the monitoring period through the post-operative phase…
- Conditions
- Revision Spine Surgery, Fusion of Spine, Cervical Fusion, Lumbar Fusion
- Trial name
- KIPSs (NCT06066879)
- Testing
- Ketamine Hydrochloride
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- AXIS Spine Center- a division of Northwest Specialty Hospital
Pain, Postoperative, Burns
Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain
Donor site pain study comparing post-operative donor site pain and opioid consumption after use of Lidocaine, Liposomal Bupivicaine or regional nerve block for split thickness skin graft harvesting in patients with less than 20%…
- Trial name
- NCT03854344
- Testing
- Lidocaine Hydrochloride, Liposomal bupivacaine, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Kansas Medical Center
Post Operative Pain
Parent Nurse Controlled Analgesic in Pediatric Patients With Developmental Delay
The purpose of this study is to compare, the safety, efficacy and level of parent and nurse satisfaction with three methods of opioid administration post-operatively in children (4-18 years of age) with developmental delay.
- Trial name
- PNCA (NCT00743730)
- Testing
- Pain and standard side effect management for PNCA with basal method., Pain and standard side effect management with PNCA without basal, Pain and standard side effect management with IV on an as needed basis method.
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Medical College of Wisconsin
Lower Limb Fracture
Comparison of Postoperative Analgesia Between Intravenous Paracetamol and Intranasal Tapentadol
The aim of the study was to compare the analgesic efficacy of intranasal tapentadol nasal spray 44.5mg and intravenous paracetamol 1gm during the postoperative period by Visual analog scale(VAS)in patients undergoing lower…
- Trial name
- NCT05999890
- Testing
- Tapentadol Hydrochloride
- Where
- India
- Volunteers
- 74 people
- Sponsor
- Kempegowda Institute of Medical Sciences, Bangalore
Ultrasound, Serratus Anterior Plane Block
Ultrasound Guided Serratus Anterior Plane Block Versus Thoracic Erector Spinae Plane Block for Post Operative Analgesia in Pediatrics Undergoing Thoracotomy
This study is designed to compare the post operative analgesic effect of serratus anterior plane block versus thoracic erector spinae plane block in pediatrics undergoing thoracotomy
- Conditions
- Ultrasound, Serratus Anterior Plane Block, Thoracic Erector Spinae Plane Block, Post Operative Analgesia
- Trial name
- NCT06862518
- Testing
- Control group, Serratus Anterior Plane Block (SAPB) group, Erector Spinae Plane Block (ESPB) group
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Tanta University
Opioid Use, Auriculotherapy
Auriculo-Nerve Stimulation on Post-Operative Opioid Requirement
The NSS-2 BRIDGE® device (NSS stands for Neuro-Stimulation System) is a disposable device that stimulates the branches of cranial nerves and of the superficial cervical plexus innervating the ear.
- Conditions
- Opioid Use, Auriculotherapy, Pain, Abdominal, Cancer Pain
- Trial name
- NCT05506878
- Testing
- NSS-2 BRIDGE
- Where
- 4 sites in United States
- Volunteers
- 286 people
- Sponsor
- Jacques E. Chelly
Postoperative Pain, Acute
Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries
Tourniquet, a compressing device, otherwise its use in intravenous regional anesthesia, is commonly used in particular orthopedic surgeries.
- Trial name
- K-IVRAg (NCT05543785)
- Testing
- Ketorolac, Control
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Mansoura University
Analgesia, Pain, Postoperative
Postoperative Analgesic Effects of Bilateral External Oblique Intercostal Block in Laparoscopic Cholecystectomy Surgery
The aim of our study is to reduce postoperative pain by performing external oblique intercostal block in L/S cholecystectomy surgeries. Our main goal is to provide well managed post-operative analgesia.
- Trial name
- NCT05444985
- Testing
- Pain Management
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Samsun University
Post-operative Pain, Cesarean Section
Post-operative Cesarean Trial of Pain Control
This study plans to learn more about postoperative pain management after cesarean deliveries (C-sections). As a part of standard of care, the Children's Hospital Colorado's Colorado Fetal Care Center (CFCC) follows the standard…
- Trial name
- NCT05131178
- Testing
- ON-Q Pump® with continuous infusion of bupivacaine, ON-Q Pump® with continuous infusion of saline
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver
Knee Osteoarthritis
Effect of Noise Control During Total Knee Arthroplasty
Music has emerged as a well-received medical intervention. Patients may be uncomfortable during total joint replacement, which can result in high sedation requirements. These requirements put patients at risk of surgical stress.
- Trial name
- NCT05714267
- Testing
- Active noise cancelling, Passive noice cancelling, Active noise cancelling with music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bezmialem Vakif University
Post-operative Pain, Opioid Use
QL vs LAI for Palatoplasty
This study will consist of patients ages 6-18 who are undergoing a surgery on the hard or soft palate of the mouth (palatoplasty), with removal of bone from the front of the hip (anterior iliac bone graft harvesting).
- Conditions
- Post-operative Pain, Opioid Use, Cleft Palate
- Trial name
- NCT06420336
- Testing
- Quadratus lumborum block, Local anesthetic infiltration
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Medical University of South Carolina
Pain, Post-operative, Third Molar
Controlled Trial to Determine Most Effective Post-Operative Analgesia After Third Molar Extraction
This is a prospective randomized clinical trial that will investigate which post-operative medications in conjunction with a multimodal analgesia approach can most effectively control post-operative pain and reduce opioid…
- Conditions
- Pain, Post-operative, Third Molar, Oral Surgery, Pain, Acute
- Trial name
- NCT06484439
- Testing
- Ketorolac, Oxycodone, Acetaminophen
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Pain, Postoperative
Study Evaluating the Effects of Toradol and Lyrica for Pain Control After Donor Nephrectomy
The investigators will assess how the use of toradol and pregabalin affects return to bowel function and see if there is a difference in length of hospital stay.
- Trial name
- NCT03669081
- Testing
- Ketorolac, Pregabalin, Saline
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Utah
Post-operative Pain
Post-operative Oral Morphine Versus Ibuprofen
Children 5-17 years of age who have undergo orthopedic day surgical procedures for definitive management of fractures, tendon release, etc.
- Trial name
- NCT01686802
- Testing
- oral morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Post Operative Analgesia, Opioid Sparing Anaesthesia
To Compare Post-op Analgesic Effectiveness of Ropivicaine+Dexamethasone and Ropivacane+Dexmetomidine in TAP Block in Stoma Reversal Under GA in Terms of Duration of Analgesia.
Controlling pain is of major concern in intra-operative as well as post-operative period inpatients undergoing all surgeries especially abdominal surgeries.Adequate pain control in post-operative period directly effect patient's…
- Conditions
- Post Operative Analgesia, Opioid Sparing Anaesthesia, Hypotension, Controlled, Bradycardia
- Trial name
- NCT07368075
- Testing
- TAP Block with Ropivacaine+Dexamethasone, TAP Block with Ropivacaine+Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Laparoscopic Cholecystectomy
Local Anesthetic Nebulization for Pain Control After Laparoscopic Cholecystectomy
Intraperitoneal nebulization of local anesthetic is a novel approach to pain management after laparoscopy. Preoperative compared with postoperative administration of analgesia remains controversial.
- Trial name
- NCT01247857
- Testing
- Ropivacaine 30 mg, Saline
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- San Gerardo Hospital
Post Operative Pain
Intermittent Bolus vs Continuous Infusion Via ESP Catheters RCT
The purpose of this prospective randomized controlled trial is to compare the effectiveness of two different delivery methods for postoperative pain management following cardiac surgery requiring median sternotomy: intermittent…
- Trial name
- NCT05642416
- Testing
- Continuous Infusion of ropivacaine, Intermittent bolus of ropivacaine
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Henry Ford Health System
Post Operative Analgesia, Hemodynamic (MAP) Stability
Comparative Study of USG Guided ESPB vs USG Guided PVB For Post-op Analgesia In Patient's After Open Renal Surgeries
Pain control following open renal surgeries are of utmost importance in order to reduce the chance of chronic pain development, and facilitate early rehabilitation.
- Conditions
- Post Operative Analgesia, Hemodynamic (MAP) Stability, Renal Surgeries, Hypertension
- Trial name
- NCT06728514
- Testing
- Erector spinae plane block group., Paravertebral Nerve Block, Inj Bupivacaine
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Sahiwal medical college sahiwal
Complication of Anesthesia
Assessing Peripheral Nerve Block Scoring Systems for Intra-Operative and Post-Operative Analgesia
The purpose of this study is to determine if Peripheral Nerve Block scoring systems are effective in predicting the achievement of intra-operative anaesthesia and post-operative analgesia.
- Trial name
- NCT02041806
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- The Adelaide and Meath Hospital
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