Clinical trials: Post-operative Pain Management
Reduce Pain After Appendectomy
Paravertebral Block for Pain Management After Appendectomy
Paravertebral Block (PVB) was shown to be a successful and useful technique of anesthesia and analgesia. Its effect was evident in thoracic and abdominal surgeries.
- Trial name
- NCT03189693
- Testing
- PVB, GA, Anesthetic injections
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Postoperative Pain, Total Knee Arthroplasty
Peri-Articular-Multimodal Drug and Oral Celecoxib in Management of Postoperative Pain of Total Knee Arthroplasty
This study is a randomized-clinical-trial on 146 patients candidate for total knee arthroplasty (TKA) who were randomly allocated to three treatment groups, including 1) a cocktail consisting of bupivacaine, morphine…
- Trial name
- NCT05324995
- Testing
- Multimodal Drug, epinephrine, celecoxib
- Where
- Iran
- Volunteers
- 146 people
- Sponsor
- Isfahan University of Medical Sciences
Quadratus Lumborum, Laparoscopic Cholecystectomy
Comparison of Ultrasound-Guided Quadratus Lumborum Plane Block Versus Intraperitoneal and Periportal Bupivacaine Infiltration in Postoperative Analgesia After Laparoscopic Cholecystectomy
The primary outcome: is measured by pain at rest and upon mobilization according to VAS. VAS for pain (ranging from 0 to 10, where 0 no pain and 10 maximum pain) will be evaluated postoperatively and every 2 hours during the…
- Conditions
- Quadratus Lumborum, Laparoscopic Cholecystectomy, Ultrasound Guided, Post Operative Analgesia
- Trial name
- NCT06721039
- Testing
- Bilateral QL block, Intraperitoneal and port sites infiltration
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- medina medical center
Breast Cancer, Postoperative Recovery
ERAS Protocols in Breast Conserving Surgery
Enhanced Recovery After Surgery (ERAS) protocols have been of increasing interest in the surgical community for decades. The emphasis has been development of protocols to maximize pain control post-operatively without the use of…
- Trial name
- ERAS (NCT06938581)
- Testing
- ERAS Protocol, Standard Perioperative Care
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- University of Nebraska
Postoperative Pain Management
Escalating Ketamine Doses and Pre-emption
Ketamine affects postoperative pain when administered intravenously immediately before, during or at the end of surgical procedures.
- Trial name
- NCT01070108
- Testing
- Ketamine
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Postoperative Analgesia for Anterior Cruciate Ligament Surgery of the Knee
Analgesic Efficacy of Saphenous Nerve Blockade for Outpatient Knee Anterior Cruciate Ligament Surgery
The purpose of this study is to determine whether blockade of the saphenous nerve can provide the same degree of analgesia postoperatively for ACLS as a femoral nerve block without resulting motor blockade enhancing shortening of…
- Trial name
- NCT02071433
- Testing
- Saphenous nerve blockade, Femoral nerve blockade
- Where
- Netherlands
- Volunteers
- 58 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Medial Patellofemoral Ligament (MPFL) Reconstruction, Sports Injuries in Children
Evaluation of Pain Management After Surgery When Using Exparel in the Pediatric Population
The goal of this randomized clinical trial is to determine if administration of Exparel via local infiltration for medial patellofemoral ligament (MPFL) reconstruction procedures in pediatric orthopaedic sports medicine patients…
- Conditions
- Medial Patellofemoral Ligament (MPFL) Reconstruction, Sports Injuries in Children, Analgesia, Pain, Postoperative
- Trial name
- NCT06559215
- Testing
- Exparel
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Post Operative Pain, Laparoscopic Hysterectomy
Preoperative Acetazolamide
The goal of this randomized study looks at whether giving patients a medicine called acetazolamide (also called Diamox) before they have laparoscopic hysterectomy may decrease postoperative pain.
- Conditions
- Post Operative Pain, Laparoscopic Hysterectomy, Referred Pain
- Trial name
- NCT07101250
- Testing
- Acetazolamide 500 MG Extended Release Oral Capsule
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Prisma Health-Upstate
Head and Neck Cancer, Pain, Musculoskeletal
Continous Popliteal Block for Microvascular Free Flap Reconstruction in Ear, Nose and Throat Surgery
The aim of the study is to assess the effects of a continuous popliteal block on postoperative pain and recovery after major ear, nose and throat surgery with microvascular free flap reconstruction using a fibula graft.
- Trial name
- NCT03607227
- Testing
- Levobupivacaine, Saline Solution
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Region Skane
Anesthesia and Analgesia, Anesthesia, Endotracheal
Opioid Free Versus Opioid Balanced Anesthesia in Ophthalmic Surgery
Anesthesia without the use of opioid (Opioid free anesthesia) is an alternative to conventional opioid balanced anesthesia, with less post operative nausea and vomiting, and comparable analgesia.
- Trial name
- NCT06382831
- Testing
- Dexmedetomidine, Fentanyl
- Volunteers
- 104 people
- Sponsor
- Universitas Indonesia
Post Operative Pain Control
Efficacy of Ultrasound Guided Erector Spinae Plane Block Versus Ultrasound Guided Serratus Anterior Plane Block for Postoperative Pain Control Following Video-assisted Thoracoscopic Surgeries (VATS): Randomized Control Trial
The aim of the study is to compare the analgesic efficacy of Erector spinae plane block versus Serratus anterior plane block in patients undergoing video-assisted thoracoscopic surgeries.
- Trial name
- NCT07360028
- Testing
- Erector Spinae (ESP) Block with Bupivacaine (Marcaine®), Serratus anterior plane block (SAP)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Femoracetabular Impingement, Pain, Postoperative
Intra-articular Morphine and Clonidine Injections for Pain Management in Hip Arthroscopy
The purpose of this study is to determine whether intraoperative (during surgery) morphine and clonidine hip injections are effective in postoperative pain management for patients undergoing hip arthroscopy.
- Trial name
- NCT02530151
- Testing
- Morphine with clonidine, Normal saline
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Northwestern University
Postoperative Analgesia, Pain Management
Comparison of Intrathecal Morphine and Rectus Sheath Block for Postoperative Pain Management After Lower Abdominal Surgery With Midline Incision
This study aims to evaluate the efficacy of intrathecal morphine and rectus sheath block compared with standard postoperative analgesia for pain management in patients undergoing lower abdominal surgery with a midline incision.
- Trial name
- NCT07489872
- Testing
- Intrathecal Morphine, Rectus Sheath Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Marmara University
Pain, Postoperative; Anesthesia, Regional
Analgesic Efficacy of Ultrasound Guided Paravertebral Block in Percutaneous Nephrolithotomy Patients
The aim of this study is to investigate the analgesic effects of thoracal paravertebral block in the patients undergoing percutaneous nephrolitotomy. Paravertebral block was applied to the study group.
- Trial name
- NCT04406012
- Testing
- paravertebral block
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Pain, Postoperative
Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
The purpose of this study is to evaluate the patient experience when using gabapentin with other pain control medications after posterior spinal fusion surgery for scoliosis in adolescents.
- Trial name
- NCT01977937
- Testing
- Gabapentin 250mg/5mL NDC:59762-5025-01, Simple Syrup
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Oregon Health and Science University
Pain, Chronic, Pain, Chronic Post-Surgical
iCanCope With Post-Operative Pain (iCanCope PostOp)
There are few applications available in the community to help teenagers manage pain after surgery. The focus of this study is to better understand the pain experience of children after having surgery and to design a Smartphone…
- Trial name
- NCT05382962
- Testing
- iCanCope Post Op Application
- Where
- 2 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- The Hospital for Sick Children
Pain
Postoperative Tramadol/Gabapentin/Ibuprofen Versus Tramadol/Placebo/Ibuprofen
Tonsillectomy is the most common pediatric surgical procedure performed in the US, with over 530,000 procedures performed annually in children under 15 years (Baugh et al., 2011).
- Trial name
- NCT02076893
- Testing
- gabapentin, Tramadol, Ibuprofen
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Post Operative Pain
Study to Compare Reduction in Pain After Surgery With and Without Local Anesthesia During Laparoscopy
This study will help to answer the question, "Does injecting local anesthetic before laparoscopic instrument ports are placed decrease pain after surgery?" Patients participating will be randomly assigned to receive local…
- Trial name
- NCT01452633
- Testing
- 0.25% bupivicaine will be injected at the study port site prior to incision, Saline will be injected at the study port site prior to incision, Saline will be in injected into the port site prior to closure
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Pain, Postoperative
Gabapentin for Postoperative Pain Management After Cardiac Surgery With Median Sternotomy
In this study we will focus on the postoperative recovery. A successful postoperative recovery should bring the patient to at least to the pre-surgical level.
- Trial name
- NCT00572208
- Testing
- Gabapentin group
- Where
- 2 sites in Denmark
- Volunteers
- 64 people
- Sponsor
- Aarhus University Hospital
Postoperative Pain, Orthognathic Surgery
Pre-Extubation Bupivacaine for Pain Control After Orthognathic Surgery
This study aims to evaluate whether injecting a long-acting local anesthetic (bupivacaine) at surgical sites before awakening from anesthesia can reduce pain and the need for opioid medications after orthognathic surgery.
- Trial name
- NCT07518225
- Testing
- Bupivacaine Infiltration, Standard medical treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Esra Beyler
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