Clinical trials: Post-operative Pain Management
Pain, Analgesia
Comparing the Outcome of Two Intraoperative Analgesia Techniques After Hepato-pancreato-biliary Surgery
Inadequate pain control after abdominal procedures may lead to adverse postoperative outcome. Epidural analgesia is currently an accepted technique in abdominal surgery, but its use has been limited in liver resections by…
- Conditions
- Pain, Analgesia, Sedation
- Trial name
- NCT01201499
- Testing
- Intrathecal morphine, Continuous IV remifentanil
- Where
- Israel
- Volunteers
- 140 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pain Management, Analgesia
Comparison of a Comfort Scale and a Numerical Pain Scale on Opioid Consumption After Surgery
The objective is to show that the use of therapeutic communication tools, in this case a comfort scale, a low cost and simple to implement method, can reduce pain and therefore the consumption of opioids in the postoperative care…
- Trial name
- COMFORT (NCT05234216)
- Testing
- Informed consent, Surgery, Comfort scale
- Where
- 29 sites in France, Lebanon
- Volunteers
- 885 people
- Sponsor
- Rennes University Hospital
Cesarean Section, Cesarean Delivery
Pain Management After Cesarean Section - A Before-and-After Cohort Study
Inadequate pain relief remains a challenge after Cesarean section (CS) and may significantly impair postoperative recovery. A recent Danish single-center study (n=100) revealed that 66% of elective CS patients experienced severe…
- Conditions
- Cesarean Section, Cesarean Delivery, Pain Management, Pain Management in Postoperative Care
- Trial name
- NCT06813638
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Nordsjaellands Hospital
Osteoarthritis, Knee, Nociceptive Pain
The Post-operative Analgesia of the Virtual Reality Using a Mirror Therapy After Total Knee Arthroplasty
It was well known that the mirror therapy could decrease pain of upper-limb amputated patients. The mirror therapy is known to make a plastic change some parts of the brain perceiving the painful body part and modulating its…
- Conditions
- Osteoarthritis, Knee, Nociceptive Pain, Virtual Reality
- Trial name
- NCT01979718
- Testing
- Mirrored Virtual reality
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Ulsan University Hospital
Postoperative Pain
Tegileridine vs Sufentanil for Postoperative Pain Management and Gastrointestinal Recovery After Major Laparoscopic Abdominal Surgery
This study is a single-center, randomized, triple-blind clinical trial designed to compare tegileridine and sufentanil for postoperative analgesia and gastrointestinal tolerability in patients undergoing major laparoscopic…
- Trial name
- TASPER (NCT07637968)
- Testing
- Tegileridine, Sufentanil, Palonosetron
- Volunteers
- 84 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Shoulder Pain
Postoperative Analgesic Effect of Infraspinatus-teres Minor Inter-fascial Block in Patients Undergoing Shoulder Surgery
It is proposed to investigate the effectiveness of ultrasound-guided intertrochanteric block of the infraspinatus minor round myofascial block not inferior to the interosseous groove brachial plexus nerve block in postoperative…
- Trial name
- NCT06240884
- Testing
- Infraspinatus-teres minor interfascial block, interscalene block
- Where
- China
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Jiaxing University
Post-operative Pain Management
Intercostal Cryoanalgesia in Double Lung Transplant Recipients
This study is testing a new way to help manage pain after a double lung transplant. Instead of relying only on strong pain medicines like opioids, doctors will use a cold-therapy probe during surgery to help numb the nerves near…
- Trial name
- NCT07281118
- Testing
- Atricure CryoSPHERE MAX Probe
- Where
- 3 sites in United States
- Volunteers
- 148 people
- Sponsor
- University of California, Los Angeles
Pain Management, Pain, Postoperative
Intrathecal Morphine Injection Versus Continuous Wound Infiltration After Pancreaticoduodenectomy
This is a prospective randomized open-label noninferiority trial that compares intrathecal morphine injection and continuous wound infiltration after open pancreaticoduodenectomy.
- Trial name
- ITM_PPPD (NCT06761989)
- Testing
- Intrathecal morphine injection, Continuous wound infiltration
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Seoul National University Hospital
Post Operative Pain
The Safety and Efficacy of Surgical Rectus Sheath Block for Postoperative Analgesia After Elective Cesarean Delivery
All participants will receive spinal anaesthesia and will be randomly divided into 2 equal groups. In Group 1, 20 ml of local anesthetic solution will be administered bilaterally to the rectus sheath space under direct vision…
- Trial name
- NCT06020196
- Testing
- surgical rectus sheath block, subdermal local anaesthetic infiltration
- Where
- Egypt
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Ahmed M Maged, MD
Acute Post-operative Pain Following Caesarean Section
Opioid-free Analgesia for the Management of Acute Post-operative Pain Following Caesarean Section
Background: Multimodal analgesia; a combination of opioid and non-opioid analgesics, for management of acute post-operative pain significantly reduces the incidence of adverse effects associated with liberal post-operative opioid…
- Trial name
- OFAAPPCS (NCT04539249)
- Testing
- Magnesium sulphate, Pentazocine
- Where
- Nigeria
- Volunteers
- 324 people
- Sponsor
- Olakunle Ifeoluwa Makinde
Post Operative Analgesia
Dexmedetomidine and Bupivacaine Intra-articular for Postoperative Analgesia After Knee Arthroscopic Surgery
The aim of this study to compare the analgesic effects of intraarticular dexmedetomidine added to bupivacaine with those of bupivacaine alone after knee arthroscopy
- Trial name
- DEXMED (NCT06665438)
- Testing
- Bupivacaine 0.25%, Dexmedetomidine
- Where
- 2 sites in Egypt
- Volunteers
- 75 people
- Sponsor
- Al-Azhar University
Pain, Chronic, Failed Back Surgery Syndrome
Burst Spinal Cord Stimulation (Burst-SCS) Study
Recently a new form of spinal cord stimulation therapy called burst spinal cord stimulation (Burst-SCS) is available to treat chronic pain. The goal of this study is to learn more about how Burst-SCS works to reduce chronic pain.
- Trial name
- NCT03718325
- Testing
- Burst-SCS
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Breast Surgery, Thoracic Paravertebral Block
Erector Spinae Plane Block Versus Thoracic Paravertebral Block for Pain Control in Modified Radical Mastectomy
The aim of the study is to compare the effectiveness of the Erector spinae plane (ESP) block versus thoracic paravertebral (TPV) block in the post-operative pain control after radical mastectomy.
- Conditions
- Breast Surgery, Thoracic Paravertebral Block, Post-operative Pain Control, Erector Spinae Plane Block
- Trial name
- NCT04457115
- Testing
- Thoracic paravertebral block, Erector spinae plane Block
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- AUSL Romagna Rimini
Pain Management
Imagined Acupuncture for Postoperative Pain After Spinal Surgery
The goal of this clinical trial is to evaluate whether imagined acupuncture can reduce postoperative acute pain in adult patients undergoing spinal surgery.
- Trial name
- NCT07197710
- Testing
- video-guided acupuncture imagery treatment (VGAIT), Education video
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Jingping Wang, MD, Ph.D.
Nose Deformities, Acquired
Effect of Ketamine Addition to Lidocaine in Rhinoplasty
The purpose of this study is to determine whether subanesthetic ketamine addition to lidocaine decreases postoperative pain scores in infiltration anesthesia during rhinoplasty.
- Trial name
- NCT01827020
- Testing
- Lidocaine 2 %, Ketamine plus Lidocaine, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Inonu University
Postoperative Pain
Pain Management After Elective Shoulder Surgery
Postoperative pain management plays an important role in elective shoulder surgery. The aim of this randomized quantitative study is to compare two frequently used postoperative pain regimes (hydromorphone versus piritramide)…
- Trial name
- NCT03541759
- Testing
- Hydromorphone Hcl 4Mg Tab, Piritramide 15mg s.c.
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- AUVA Traumazentrum Vienna Site UKH Meidling
Endodontically Treated Teeth, Post Operative Pain
Bioceramics Pain Control
Postoperative pain in endodontic retreatment cases presents a challenge to any endodontist. Tricalcium silicate materials as mineral trioxide aggregate (MTA) and bioceramics have shown favorable periapical tissue reactions and…
- Trial name
- NCT05399303
- Testing
- obturation
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Misr International University
Obesity
Ibuprofen and Erector Spinae Plane Block After Laparoscopic Sleeve Gastrectomy
Laparoscopic sleeve gastrectomy (LSG) is defined as the first-step bariatric surgery for patients in the high surgical risk group.
- Trial name
- NCT04232072
- Testing
- Group ESPB, Group Ibuprofen
- Where
- Turkey (Türkiye)
- Sponsor
- Medipol University
Lung Cancer, Pain, Postoperative
Optimal Postoperative Pain Management After Lung Surgery (OPtriAL)
Adequate pain control after video-assisted thoracoscopic surgery (VATS) for lung resection is important to improve postoperative mobilisation, recovery, and to prevent pulmonary complications.
- Conditions
- Lung Cancer, Pain, Postoperative, VATS, Locoregional Anaesthesia
- Trial name
- NCT05491239
- Testing
- Thoracic epidural analgesia, Continuous regional paravertebral block, Single shot intercostal nerve block
- Where
- Netherlands
- Volunteers
- 450 people
- Sponsor
- Maxima Medical Center
Postoperative Analgesia
Adductor Canal Block With IPACK Versus Genicular Nerves Block With IPACK for Post-operative Analgesia
In our study, we will find out the efficacy of those peripheral nerve blocks on postoperative pain in knee arthroscopy. The aim is to evaluate the efficacy of combined ultrasound-guided IPACK with adductor canal nerve block…
- Trial name
- IPACK (NCT07258277)
- Testing
- IPACK with adductor canal block, IPACK with Genicular nerves block, Spinal Block
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Minia University
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