Clinical trials: Post-operative Pain Management
Pain, Post Operative Nausea and Vomiting
Satisfactory Analgesia Minimal Emesis in Day Surgeries
Currently nearly 70% or more surgeries are being done as ambulatory (day care) procedures as they offer significant benefit to the patients as well as to the hospitals.
- Trial name
- SAME-Day (NCT02223377)
- Testing
- Morphine, Hydromorphone
- Where
- 2 sites in Canada
- Volunteers
- 402 people
- Sponsor
- McMaster University
Supracondylar Humerus Fracture
Post-operative Pain Management in Children With Supracondylar Humerus Fractures
There are two common and concurrently used strategies for pain management following surgical treatment of supracondylar humerus (elbow) fractures in children: opioids vs over the counter pain medications.
- Trial name
- NCT05640674
- Testing
- Ibuprofen, Hydrocodone/acetaminophen, Acetaminophen
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- Baylor College of Medicine
Quadratus Lumborum Block, Abdominoplasty
Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery
Abdominoplasty is a common surgical procedure in plastic surgery which causes postoperative pain and may delay patients' recovery.
- Conditions
- Quadratus Lumborum Block, Abdominoplasty, Analgesia, Locoregional Anesthesia
- Trial name
- QLB (NCT04670224)
- Testing
- QLB anesthesia, Intravenous anesthesia without QLB
- Where
- France
- Volunteers
- 286 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pain, Post Operative, Cesarean Section Complications
Erector Spinae Plane Block (ESPB) Versus Quadratus Lumborum Block (QLB) for Postoperative Analgesia After Caesarean Section
Management of pain after caesarean section represents an important anesthesiologic issue, since it is often suboptimal, leading to delayed functional recovery and chronic pain.
- Conditions
- Pain, Post Operative, Cesarean Section Complications, Anesthesia, Local, Obstetric Anesthesia Problems
- Trial name
- NCT05348083
- Testing
- ESPB
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Post Operative Pain, Femur Fracture
Volume Dependent Effect of Pericapsular Nerve Block
In PENG block technique, the local anesthetic agent is injected between the psoas tendon and the pubic ramus to block the sensory branches of the nerves which innervates the hip capsule for providing analgesia without causing…
- Trial name
- NCT05256056
- Testing
- Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Postoperative Pain, Gas Bloat Syndrome
The Effect of Kinesio Taping and Breathing Exercises on Pain Management
A randomised clinical trial in a single centre.The aim of this study is to evaluate the effect of kinesio taping and breathing exercises on pain management applied after benign gynecological abdominal operations.
- Conditions
- Postoperative Pain, Gas Bloat Syndrome, Defecation Disorders
- Trial name
- NCT04412122
- Testing
- Kinesio Taping, Breathing Exercise, Kinesio Taping+Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Acute Pain, Post Operative Pain
Intrathecal Hydromorphone for Postoperative Pain of Anorectal Surgery
Anorectal problems, such as hemorrhoids, fistula, fissures, Etc., often require surgical treatment. Patients often have postoperative pain after these surgeries, which increases discomfort and hospital length of stay.
- Conditions
- Acute Pain, Post Operative Pain, Anorectal Disorder, Analgesia
- Trial name
- IMPAS (NCT05579223)
- Testing
- Intrathecal Hydromorphone Mono Injection
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Breast Diseases
Serratus Posterior Superior Interfascial Plane Block for Breast Surgery
Regional techniques can be used for postoperative pain control following breast surgery. Ultrasound (US) guided serratus posterior superior block (SPSPB) is a new interfacial plane block defined by Tulgar et al in 2023.
- Trial name
- NCT05972083
- Testing
- Analgesia management; group S and C
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Pain Postoperative
OSTAP Versus TAP for Postoperative Pain Management in Laparoscopic Cholecystectomy Patients
The aim of the study is to compare the effectiveness and opioid sparing effects of TAP and OSTAP in patients undergoing laparoscopic cholecystectomy.
- Trial name
- OSTAP/TAP (NCT03954795)
- Testing
- TAP, OSTAP
- Volunteers
- 75 people
- Sponsor
- Balikesir University
Postoperative Pain
Comparison of Quadratus Lumborum Block and Epidural Analgesia Following Kidney Transplant Surgery
Quadratus lumborum block as an alternative for postoperative analgesia compared with epidural block
- Trial name
- NCT03771339
- Testing
- Continuous Epidural analgesia, Bilateral Quadratus Lumborum block
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Postoperative Analgesia, Postoperative Pain Management
Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia
In this study the participants aim to Compare The Effect of Intravenous Combination Dexmedetomidine _ Ketamine versus Dexmedetomidine on Post-Operative Analgesia In Vaginal Hysterectomy Proceeded Under Spinal Anesthesia regarding…
- Trial name
- NCT07330375
- Testing
- Dexmedetomidine, Ketamine, Saline (0.9% NaCl)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Acute Pain
A Phase 2 Study to Evaluate Analgesic Effect of IV CR845 For Pain Following Bunionectomy Surgery
This is a single-center, randomized, double blind, placebo controlled, parallel group proof of concept study to evaluate the analgesic efficacy as well as the safety, tolerability and pharmacokinetic profile of CR845 in patients…
- Trial name
- NCT01789476
- Testing
- CR845
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Cara Therapeutics, Inc.
Disease Status of Pancreatobiliary Tract , ( Especially Who Need to Undergo Pancreaticoduodenectomy)
Postoperative Muscular Pain, ETOIMS (Electrical Twitch Obstructive Intramuscular Stimulation)
Pancreaticoduodenectomy is inevitably an operation requiring extensive skin and muscle incision, resulting in postoperative pain resulting in limitation of the patient's early exercise and function.
- Trial name
- NCT03619343
- Testing
- ETOIMS(Electrical Twitch Obtaining Intramuscular Stimulation)
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Yonsei University
Anterior Cruciate Ligament Reconstruction
Study of Pain Management Techniques Following Anterior Cruciate Ligament Repair Surgery
Patients scheduled to undergo knee arthroscopy with anterior cruciate ligament repair with graft from the ipsilateral hamstrings and gracilis will be randomized to one of three groups.
- Trial name
- NCT01868282
- Testing
- Hamstrings block, Obturator block, Control group
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Postoperative Pain, Post Operative Analgesia
Continuous Infusion of Dexamethasone Plus Tramadol Adjunct to Morphine PCA After Abdominal Hysterectomy
Dexamethasone has been recognized as an antiemetic agent after surgeries, and the combination of dexamethasone and tramadol remained stable in solution up to 5 days. In addition, i.v.
- Conditions
- Postoperative Pain, Post Operative Analgesia, Patient-Controlled Analgesia, Abdominal Surgeries
- Trial name
- DTMPCA (NCT00564603)
- Testing
- Dexamethasone Sodium Phosphate Injection, 0.9% Saline
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Nanjing Medical University
Postoperative Pain, Satisfaction with Care
Thoracic Spinal Versus Thoracic Epidural Anesthesia for Patients with Chronic Obstructive Pulmonary Disease Undergoing Supine Percutaneous Nephrolithotomy for Management of Renal Stones.
Owing to the elevated risk of perioperative comorbidities, chronic obstructive and restrictive pulmonary disorders can be a challenging task for the anesthetist.
- Trial name
- NCT06663488
- Testing
- Thoracic epidural anesthesia, Thoracic spinal anesthesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Postoperative Analgesia, Laparoscopic Hysterectomy
Preemptive Analgesia in Laparoscopic Hysterectomy
The aim of this study is to evaluate the effects of ibuprofen and paracetamol administered for pre-emptive analgesia to patients undergoing laparoscopic hysterectomy on pain scores during the first 24 hours postoperatively, the…
- Trial name
- NCT07401927
- Testing
- Ibuprofen, Parasetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Giresun University
Hysterectomy, Myoma
Morphine vs. Oxycodone for Postoperative Pain Management
The purpose of this study is to determine whether oxycodone provides better analgesia compared to morphine after laparoscopic hysterectomy or myomectomy.
- Conditions
- Hysterectomy, Myoma, Postoperative Pain, Opioids
- Trial name
- NCT00528177
- Testing
- Morphine and oxycodone
- Where
- Norway
- Volunteers
- 90 people
- Sponsor
- Ullevaal University Hospital
Acute Pain, Surgery
Clinical Study to Evaluate Clinical Impact of PGx-Guided Treatment for Patients Undergoing Elective Spinal Surgical Procedures
The purpose of this study is to evaluate the effect of pharmacogenetic (PGx) guided treatment when implemented into the pre-operative process for patients undergoing an elective spinal surgical procedure and requiring…
- Trial name
- NCT02599870
- Testing
- NeuroIDgenetix Test Panel
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- AltheaDx
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