Clinical trials: Post-operative Wound Healing
Pain, Post Operative, Anxiety
Music Therapy in the Treatment of Perioperative Anxiety and Pain
A large number of adults who undergo surgery experience perioperative anxiety and pain. The current recommended approach to perioperative pain management is a multimodal approach including opioids.
- Conditions
- Pain, Post Operative, Anxiety, Opioid Use
- Trial name
- NCT05263635
- Testing
- Music therapy, Standard of Care Enhanced Recovery After Surgery (ERAS)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pittsburgh
Wound Healing Disorder, Impaired Wound Healing
Treatment Study of Vacuum Assisted Closure for Postsurgical Subcutaneous Abdominal Wound Healing Impairments
This clinical study is performed in several German, Dutch and Belgian hospitals to evaluate the efficacy of Vacuum Assisted Closure® (V.A.C.®) for the treatment of postsurgical abdominal wound healing impairments after surgery.
- Conditions
- Wound Healing Disorder, Impaired Wound Healing, Abdominal Wound Healing Disorder, Abdominal Wound Healing Impairment
- Trial name
- SAWHI (NCT01528033)
- Testing
- Vacuum Assisted Closure®, Standard conventional wound therapy
- Where
- 15 sites in Belgium, Germany
- Volunteers
- 539 people
- Sponsor
- University of Witten/Herdecke
Scoliosis; Juvenile, Scoliosis; Adolescence
Virtual Reality's Effect on Decreasing Pain and Subsequent Opioid Use in Pediatric Patients in the Post-Operative Period Following Scoliosis Repair
The goal of this study is to determine whether introducing VR in the immediate post-operative period following scoliosis repair can reduce perceived pain and stress in pediatric patients and in turn ultimately decrease opioid…
- Conditions
- Scoliosis; Juvenile, Scoliosis; Adolescence, Scoliosis
- Trial name
- NCT05888038
- Testing
- virtual reality
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Northwell Health
Androgenetic Alopecia, Wound Healing
Topical Rifamycin SV for Wound Healing After Sapphire FUE Hair Transplantation
This prospective, parallel-group controlled clinical study evaluated whether a single topical rifamycin SV protocol added to standardized care after sapphire follicular unit extraction (FUE) was associated with earlier recorded…
- Trial name
- NCT07155408
- Testing
- Povidone-Iodine 10%, Rifamycin SV Sodium
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Elif Asena KANTARCI
Complications; Arthroplasty, Infection or Inflammation, Wound Complication
Improvement in Wound Healing With Negative Pressure Wound Therapy for Postoperative Total Hip Arthroplasty
For the target population of adult patients following primary total hip arthroplasty, the randomized clinical trial will be used to evaluate the efficacy of the use of a mobile negative pressure wound therapy(NPWT) device…
- Trial name
- NCT02355691
- Testing
- PREVENA
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of North Carolina, Chapel Hill
Hernia, Ventral Hernia
Prospective Clinical Evaluation of High-Purity Type I Collagen in Select High-Risk Hernia Repair Scenarios
This prospective, single-arm clinical study evaluates the safety, feasibility, and early clinical outcomes of High-Purity Type I Collagen (HPTC; Surgicoll-Mesh®) when used as a biologic reinforcement in selected hernia repair…
- Conditions
- Hernia, Ventral Hernia, Incisional Hernia, İnguinal Hernia
- Trial name
- NCT07360691
- Testing
- High-Purity Type I Collagen Mesh
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Gingival Recession
Post-operative Blood Flow Measurements of the Oral Mucosa
Our overall goal is to characterize the role of the microcirculation in healing oral mucosa after routinely applied surgery intervention in order to facilitate treatment.
- Trial name
- LASCAM (NCT02540590)
- Testing
- laser speckle contrast imaging of the oral mucosa, wound fluid measurement
- Where
- Hungary
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Surgical Site Infection
Wound Antiseptic Study With Hypochlorous Acid & Iodopovidone
The purpose of this study is to determine whether hypochlorous acid is an effective antiseptic agent to prevent surgical site infection.
- Trial name
- WASH (NCT00692757)
- Testing
- Hypochlorous acid, Iodopovidone
- Where
- Colombia
- Volunteers
- 432 people
- Sponsor
- Universidad Tecnológica de Pereira
Perianal Abscess
Effect of Red and Blue Light Irradiation on Postoperative Wound Healing in Perianal Absces
This study aims to investigate whether specialized red-blue light irradiation facilitates faster postoperative recovery and reduces complication rates in patients following perianal abscess surgery.
- Trial name
- NCT07155356
- Testing
- Red light exposure, Red-blue light exposure
- Where
- China
- Volunteers
- 222 people
- Sponsor
- The Affiliated Hospital of Putian University
Spine Surgery
Trial of Protein Supplement on Vertebral Fusion in Posterior Spine Fusion Surgery
Receiving protein can affect the bone formation and maintenance by providing a structural matrix of the bone, optimizing the level of IGF-1, increasing intestinal calcium absorption, transferring phosphorous, and improving muscle…
- Trial name
- NCT04091841
- Testing
- protein supplement, Carbo Mass
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Shahid Beheshti University
Post-surgical Scars, Hypertrophic Scars
Surgical Care And Recovery With Laser Evaluation Trial (SCARLET)
The Surgical Care and Recovery with Laser Evaluation Trial (S.C.A.R.L.E.T.) is a prospective, single-center clinical study conducted at AdventHealth Medical Group Plastic and Reconstructive Surgery at Innovation Tower.
- Conditions
- Post-surgical Scars, Hypertrophic Scars, Scar Appearance Dissatisfaction, Aesthetic Surgical Outcomes
- Trial name
- SCARLET (NCT07359352)
- Testing
- ProFractional Laser Therapy and/or Broadband Light (BBL) Treatment
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Post Operative Pain (Post Laparoscopic Hernia Repair)
Effects of Local Anesthesia on Post-operative Pain During Laparoscopic Inguinal Hernia Repair
To assess effect of local anesthetic into the preperitoneal space during laparoscopic hernia repair on post-operative pain.
- Trial name
- NCT02055053
- Testing
- 0.5% Bupivicaine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Lahey Clinic
Intrauterine Adhesion
Effects of Aspirin on Uterine Endometrial Repair Severe Intrauterine Adhesion
This study aimed To investigate the effects of estrogen in combination with aspirin and intrauterine balloon on the uterine endometrial repair and reproductive prognosis in patients after surgery for severe intrauterine adhesion .
- Trial name
- NCT02744716
- Testing
- Aspirin, intrauterine balloon
- Where
- China
- Volunteers
- 114 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Complication,Postoperative
Heparin Alone vs. Heparin-Aspirin Combo in Free Flap Survival
This randomized clinical trial aims to compare the effectiveness of heparin alone versus combination therapy of Heparin- Aspirin in improving free flap survival in patients undergoing reconstructive surgery.
- Trial name
- NCT06512233
- Testing
- LMW Heparin 5000 U/ML-Aspirin 75 MG, LMW Heparin 5000 U/ML
- Where
- Pakistan
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Pain Management of Inguinal Herniorrhaphy
Ultrasound-Guided Transversalis Fascia Plane Block Versus Transmuscular Quadratus Lumborum Block for Post-operative Analgesia in Inguinal Hernia Repair
Regional blocks as a part of multimodal analgesia can improve pain control in the postoperative period. The transversalis fascia plane (TFP) block can block the proximal portions of the T12 and L1 nerves, while the main advantage…
- Trial name
- NCT04026243
- Testing
- QL block, TF block
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Wound Healing Disorder, Post-Surgical Complication
NovoX®Cup as Primary Dressing After Breast Reduction
Breast reduction is one of the most frequently performed plastic surgeries. Studies have shown that breast reduction surgery significantly improves the patients' suffering and leads to a better health-related quality of…
- Conditions
- Wound Healing Disorder, Post-Surgical Complication, Mammaplasty
- Trial name
- NCT06420323
- Testing
- Treatment with NovoX® Cup, Treatment with Omnistrip®
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- MOSS S.p.A.
Cesarean Section
The Effect of Amniotic Membrane Application on Post-Cesarean Wound Healing and Cosmetic Outcomes
This clinical trial evaluates the effectiveness of amniotic membrane application during cesarean delivery in reducing post-surgical complications and improving wound healing and cosmetic outcomes in women aged 18-40 undergoing…
- Trial name
- Amniotic Membr (NCT06770946)
- Testing
- Amniotic Membrane Application
- Where
- Turkey (Türkiye)
- Volunteers
- 372 people
- Sponsor
- Yuzuncu Yil University
Surgical Wound Infection
VAC NPWT KCI Dressing Study
In this study, the investigators propose using negative pressure wound therapy (NPWT) to aid in wound healing along the lines of closure for lower extremity amputation and complex abdominal wounds.
- Trial name
- NCT01366105
- Testing
- V.A.C. by K.C.I.
- Where
- United States
- Sponsor
- Georgetown University
Inguinal Hernia Repair, Post Operative Pain
Nitrous Oxide On Acute Postoperative Pain and Opioid Consumption and Chronic Pain After Inguinal Hernia Repair Surgery
To compare postoperative pain, opioid consumption and chronic pain in patients undergoing to hernia repair surgery after receiving nitrous oxide or oxygen during the general anesthesia.
- Trial name
- NCT01622322
- Testing
- Nitrous Oxide, oxygen
- Where
- Turkey (Türkiye)
- Sponsor
- The Cleveland Clinic
Complications of Surgical Procedures, Surgical Site Infection
Quick Skin Sealant in Closure of Surgical Wound After Laparoscopic Surgery
The purpose of this study is to evaluate the short-term effect of sealant-assisted skin closure in prevention of surgical site infection after laparoscopic surgery.
- Conditions
- Complications of Surgical Procedures, Surgical Site Infection, Gastric Cancer, Colorectal Cancer
- Trial name
- NCT02426762
- Testing
- Laparoscopic surgery, Skin sealant
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University