Clinical trials: Post-operative Wound Healing
Post-operative Healing Following Blepharoplasty and Ptosis Repair
Efficacy of Loteprednol Ointment Following Eyelid Surgery
Inflammation occurs after any type of incisional surgery. This study will evaluate the efficacy of Loteprednol etabonate ointment vs. Soothe ointment (vehicle) for postoperative inflammation after routine eyelid surgery.
- Trial name
- NCT01749241
- Testing
- Loteprednol etabonate ophthalmic ointment, Vehicle Ophthalmic Ointment
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Dry Socket, Postoperative Infections
The Effect of Chlorhexidine + Hyaluronic Acid on Postoperative Wound Healing After Lower Third Molar Removal
Our aim is to evaluate chlorhexidine-hyaluronic acid containing gel on postoperative wound healing regarding impacted lower third molar surgery.
- Trial name
- NCT07044219
- Testing
- Third molar surgery
- Where
- Hungary
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Scar, Skin Scarring
Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
Patients will be randomized either to receive standard daily dressing or hydrocolloid dressing using a randomization generator. After closing the wound with the sutures,the scar will be covered by a hydrocolloid dressing, which…
- Conditions
- Scar, Skin Scarring, Skin Cancer, Wound Heal
- Trial name
- NCT05618912
- Testing
- Hydrocolloid dressing, Petrolatum jelly dressing
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Indiana University
Post Operative Pain
Open and Endoscopic Technique in Female Inguinal Hernia Repair. FemaleHernia
This randomized study compares open inguinal hernia repair (Lichtenstein hernioplasty) to endoscopic repair (TEP) in terms of chronic pain and recurrences in one and five years after operation.
- Trial name
- NCT05863624
- Testing
- Open hernioplasty, TEP hernioplasty
- Where
- Finland
- Volunteers
- 170 people
- Sponsor
- Kuopio University Hospital
Surgical Wound, Wound Healing Delayed
Using AI Within Digital Wound Monitoring of Surgical Wounds to Prioritise Non-healing Wounds for Urgent Review
The goal of this clinical trial is to learn if artificial intelligence within digital wound monitoring of surgical wounds can prioritise non-healing wounds for urgent review in patients having first/redo CABG surgeries with or…
- Conditions
- Surgical Wound, Wound Healing Delayed, Heart; Surgery, Heart, Functional Disturbance as Result
- Trial name
- WISDOM (NCT06475703)
- Testing
- Isla wound prioritisation module, Standard follow-up
- Where
- 2 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Stoma Ileostomy, Surgical Wound
The Use of Post-operative NPWT Dressing in the Prevention of Infectious Complications After Ostomy Reversal Surgery
Introduction: Although negative-pressure wound therapy (NPWT) is likely advantageous for wound healing, the efficacy and safety of its prophylactic use remain unclear.
- Conditions
- Stoma Ileostomy, Surgical Wound, Negative Pressure Wound Therapy, Postoperative Wound Infection
- Trial name
- NCT04088162
- Testing
- Postoperative Negative Pressure Wound Therapy KCI NANOVA
- Where
- 2 sites in Poland
- Volunteers
- 70 people
- Sponsor
- Michał Pędziwiatr
Inguinal Hernia Unilateral
Comparison of Mean Duration of Post Operative Analgesia Following QL-2 Block vs QL-3 Block Using Ropivacain 0.25% in Patients Undergoing Unilateral Inguinal Hernia Repair
To compare the mean dulation of post operative analgesia following QL2 block (posterior quadratus lumborum block) and the QL3 block (transmuscular quadratus lumborum block) using ropivacaine 0.25% in patients undergoing…
- Trial name
- NCT07200076
- Testing
- Quadratus Lumborum (QL) Block
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Quaid-e-Azam Medical College
Impacted Third Molar Tooth, Surgical Wound Healing
Antibacterial Effect and Soft Tissue Healing of Chlorhexidine-Coated Polyglactin 910 Sutures After Impacted Lower Third Molar Surgery
This study evaluates whether coating Polyglactin 910 sutures with chlorhexidine diacetate (CHX-DA) improves outcomes after the surgical removal of impacted mandibular (lower) third molars (wisdom teeth).
- Trial name
- NCT07794280
- Testing
- Chlorhexidine Diacetate-Coated Polyglactin 910 Suture, Uncoated Polyglactin 910 Suture
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Pain, Postoperative, Healing Surgical Wounds
Use of Cyanoacrylate in Healing and Pain in the Palatal Donor Site of Connective Tissue Grafts
Periodontal plastic surgery has been performed successfully for a long time in the treatment of gingival recessions and mucogingival defects.
- Trial name
- NCT06116539
- Testing
- Cyanoacrylate, Suture
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alfonso X El Sabio University
Rotator Cuff
Post-operative Mobilisation After Rotator Cuff Repair
The aim of this study is to compare rehabilitation with the wearing of a sling, to rehabilitation without any immobilization after an arthroscopic repair of the supraspinatus tendon.
- Trial name
- NCT02943005
- Testing
- Rotator cuff repair
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- La Tour Hospital
Skin Transplantation, Skin Grafting
Lower Extremity Graft Study (LEGS): A Multicentre Randomised Controlled Trial of Negative Pressure Wound Therapy Versus Conventional Dressings for Split-thickness Skin Grafts After Lower Leg Skin Tumour Excision
The goal of this clinical trial is to compare the effect of negative pressure wound therapy (NPWT) versus traditional dressings on the incidence of transplant infection in adult patients undergoing split-thickness skin grafting…
- Conditions
- Skin Transplantation, Skin Grafting, Split Thickness Skin Graft, Negative-Pressure Wound Therapy
- Trial name
- LEGS (NCT07040683)
- Testing
- Negative Pressure Wound Therapy (NPWT), Traditional Dressing
- Where
- Sweden
- Volunteers
- 232 people
- Sponsor
- Region Skane
Surgical Wound Infection, Cesarean Wound; Dehiscence
Sucrose as a Standard in Cesarean Section Surgical Wound Healing to Reduce Hospital Time
It is a randomized, single-blind clinical trial, whose population to be studied will be randomized patients with a diagnosis of dehiscence and infection of a cesarean surgical wound who meet the inclusion and exclusion criteria.
- Trial name
- SAGRA (NCT06477770)
- Testing
- Clorhexidine soap, Sucrose
- Where
- Honduras
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Use of Pessary Reduce the Number of Prolapse Recurrence, Uterine Prolapse
The Effect of Pessary Post Vaginal Prolapse Repair, for One Month, to Reduce the Recurrence Rate of Prolapse
Genital prolapse is a common complain. 30-40% of women will complain of uterine prolapse or cystocele or rectocele, or mixed. About half of them will require surgical repair for the prolapse, with or without hysterectomy.
- Conditions
- Use of Pessary Reduce the Number of Prolapse Recurrence, Uterine Prolapse, Cystocele, Rectocele
- Trial name
- pfgp (NCT03056586)
- Testing
- vaginal pessary
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Postoperative Complications, Obesity
Negative Pressure Wound Therapy in Obese Gynecologic Oncology Patients
The purpose of the study is to test whether the use of a new wound closure technique can decrease the rates of wound complications in obese cancer patients.
- Conditions
- Postoperative Complications, Obesity, Gynecologic Neoplasms
- Trial name
- NCT02309944
- Testing
- Standard Wound Closure, Prevena™ Incision Management System
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Postoperative Complications, Surgical Site Infection
Hierarchy of Effects of Laboratory Markers and Their Interaction With Comorbidity Concerning Outcome and Personalized Treatment of Trauma Patients in Emergency Care and Rehabilitation
At least ten percent of trauma patients suffer from any sort of complication. The study aims to identify a risk factor profile to early identify trauma patients at risk.
- Conditions
- Postoperative Complications, Surgical Site Infection, Wound Infection, Non-healing Wound
- Trial name
- HELICOPTER (NCT06758427)
- Where
- Germany
- Volunteers
- 2,300 people
- Sponsor
- Department of Trauma and Reconstructive Surgery at Eberhard Karls University Tuebingen, BG Klinik Tu
Pain, Postoperative, Wound Heal
Clinical Efficacy of Soft Tissue Trimmer in Cases of Gingival Hyperplasia.
Postoperative pain and wound healing are compared after using conventional scalpel technique in comparison with the intervention which is using Soft tissue Trimmer for cases of gingival hyperplasia.
- Conditions
- Pain, Postoperative, Wound Heal, Gingival Hyperplasia
- Trial name
- NCT04542486
- Testing
- Excision of gingival hyperplasia using "Soft tissue trimmer "., Excision of gingival hyperplasia using the conventional scalpel technique
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative
Defining the Best Approach to Block the Pain After Knee Surgery
The study aims to compare standard techniques used to control pain after knee surgery. The investigators hypothesize that the fascia iliaca block is faster, safer and as good as or better than the femoral block, with or without a…
- Trial name
- NCT00294073
- Testing
- Fascia Iliaca Block, Femoral Block (with stimulating catheter), Femoral Block (without stimulating catheter)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Hemorrhoid
Posthemorrhoidectomy Pain Management With Electronic Bidet or Sitz Bath
The investigator will perform a randomized clinical trials to compare the effect of pain management and wound healing after hemorrhoidectomy between warm sitz bath and electronic bidet.
- Trial name
- NCT02353156
- Testing
- Electronic bidet, Sitz bath
- Volunteers
- 76 people
- Sponsor
- Seoul National University Hospital
Bone Augmentation, Alveolar Ridge Augmentation
Alveolar Ridge Reconstruction in Post-extraction Sites Using a Magnesium Resorbable Membrane. An Explorative Study
When a tooth is removed, the surrounding bone and gum tissue naturally shrink over time. This shrinkage can make it harder to place a dental implant later and may affect the appearance of the smile.
- Trial name
- NOVAMAG-2024 (NCT07646795)
- Testing
- NOVAMag®
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Martina Stefanini
Impacted Mandibular Third Molar, Postoperative Wound Healing
Soft Tissue Healing and Bacterial Load With Triclosan-Coated Sutures After Impacted Mandibular Third Molar Surgery
The goal of this clinical trial is to learn if triclosan-coated absorbable stitches (polyglactin 910 sutures coated with triclosan, an antibacterial agent) help soft tissue heal better and have fewer bacteria stuck to the…
- Trial name
- NCT07386366
- Testing
- Triclosan-coated Polyglactin 910 suture, Non-coated polyglactin 910 suture
- Where
- Vietnam
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City