Clinical trials: Post-operative Wound Healing
Wound Healing
Effects of CGF and Collagen Fleece on Palatal Donor Site Healing: A Randomized Clinical Trial
This study investigated whether applying Concentrated Growth Factor (CGF) or Collagen Fleece (CF) to the palatal donor site after autogenous soft tissue graft harvesting could improve wound healing and reduce postoperative…
- Trial name
- PAL-HEAL (NCT07367165)
- Testing
- Concentrated Growth Factor (CGF), Collagen Fleece (CF), Collagen Sponge (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Inonu University
Impacted Mandibular Third Molar, Wound Healing
Adjacent Molar Outcomes After Third Molar Surgery With PRF or Collagen Sponge
This study aims to compare platelet-rich fibrin (PRF) and an absorbable collagen sponge in extraction sockets following impacted mandibular third molar removal in terms of postoperative clinical healing and periodontal and…
- Conditions
- Impacted Mandibular Third Molar, Wound Healing, Postoperative Pain
- Trial name
- PRFvsCOLL-3M (NCT07530068)
- Testing
- Platelet-rich fibrin (PRF), Absorbable Collagen Sponge
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gingival Recession, Localized, Postoperative Morbidity
Palatal Wound Healing After Free Gingival Graft Surgery
This randomized controlled clinical trial aims to evaluate the effects of topical triamcinolone acetonide application on wound healing and patient-reported outcomes at the palatal donor site following free gingival graft (FGG)…
- Conditions
- Gingival Recession, Localized, Postoperative Morbidity, Palatal Donor Site Wound Healing
- Trial name
- NCT07409571
- Testing
- kollajen membran (Cytoplast™ RTMFOAM™, Osteogenics Biomedical Inc., Texas, ABD), triamcinolone acetonide
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Surgical Site Infection, Skin Cancer
Cyanoacrylate Skin Adhesive After Mohs Surgery or Wide Local Excision
This study will compare surgical site infection after linear repair with or without cyanoacrylate skin adhesive following Mohs micrographic surgery or wide local excision.
- Conditions
- Surgical Site Infection, Skin Cancer, Wound Healing
- Trial name
- NCT07844681
- Testing
- Cyanoacrylate Skin Adhesive, Fast Gut Running Epidermal Suture Closure, Vicryl Rapide Running Epidermal Suture Closure
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Minnesota
ExtraCorporeal Life Support (ECLS), Wound Infection
Investigating the Impact of Cold Atmospheric Plasma Treatment on Wound Healing at Cannulation Sites in Patients Following Extracorporeal Life Support
This study aims to evaluate a new wound treatment called cold atmospheric plasma (CAP) for patients receiving extracorporeal life support (ECLS).
- Conditions
- ExtraCorporeal Life Support (ECLS), Wound Infection, Surgical Site Infection, Delayed Wound Healing
- Trial name
- NCT07501897
- Testing
- Cold Atmospheric Plasma (CAP) Therapy, Standard wound care
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- National Taiwan University Hospital
Scar, Breast Neoplasms
Aesthetic Effect of Steri-Strip Orientation on Healing and Scar Appearance in Breast Surgery
All patients undergoing breast biopsy, lumpectomy, needle-localization-guided breast biopsy, and mastectomy at Einstein Medical Center Philadelphia, Einstein Medical Center Montgomery, Center One, or Einstein Elkins Park will be…
- Conditions
- Scar, Breast Neoplasms, Breast Diseases, Surgical Wound
- Trial name
- NCT04554316
- Testing
- Steri-strip
- Where
- 2 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Orthopaedics Wound Dressings
Comparative Efficacy of Advanced and Traditional Wound Dressings in Post-Operative Orthopedic Care
Title: Comparative Efficacy of Advanced and Traditional Wound Dressings in Post-Operative Orthopedic Care: A Randomized Controlled Trial Objective: The primary objective of this study is to evaluate and compare the efficacy of…
- Trial name
- NCT06540040
- Testing
- Aquacel Ag, OPSITE, MEPILEX POST OP BORDER
- Where
- India
- Volunteers
- 320 people
- Sponsor
- Nidhi Srivastava
Zygomatic and Lefort II Fractures, Infraorbital Rim Fixation
Post-operative Lower Eyelid Massage for Prevention of the Lower Eyelid Scare Contracture After Subciliary Approach
Patients were randomly allocated to the lower eyelid massage (experimental) or standard care (control) groups. The massage group received post-operative instructions.
- Conditions
- Zygomatic and Lefort II Fractures, Infraorbital Rim Fixation, Subciliary Approach Repair
- Trial name
- RCT (NCT06311318)
- Testing
- lower eyelid massage
- Volunteers
- 59 people
- Sponsor
- Chiang Mai University
Perforated Duodenal Ulcer
Early Oral Feeding vs Traditional Post-operative Care In Emergency Abdominal Surgeries
ABSTRACT BACKGROUND: Enhanced recovery after surgery (ERAS) protocols have been widely studied in elective abdominal surgeries and have shown better outcomes.
- Trial name
- NCT04431037
- Testing
- Early oral feeding/Enhanced recovery after surgery protocols
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- College of Physicians and Surgeons Pakistan
Post-Operative Pain
Transversus Abdominus Plane Catheters for Open Inguinal Hernia Repair
This study is designed to evaluate pain control of continuous transversus abdominis plane (TAP) blocks placed for open inguinal hernia repair.
- Trial name
- NCT02741492
- Testing
- Transversus Abdominis Plane Block
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Benaroya Research Institute
Clavicle Fracture
Interscalene vs. Superficial Cervical Block vs. Combination for Analgesia After Clavicle Fracture
The optimal analgesic peripheral nerve block (or combinations thereof) are undefined for clavicle fractures, the most frequent fracture in the human population.
- Trial name
- NCT03094481
- Testing
- SCPB, ISB, SCPB + ISB
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Sunnybrook Health Sciences Centre
Periapical Periodontitis, Periradicular Lesion
Accuracy and Healing Outcomes of Endodontic Surgery Using a Static Surgical Guide.
The goal of this clinical trial is to evaluate the surgical accuracy and healing outcomes of endodontic surgery performed with the assistance of a 3D-printed static surgical guide in patients requiring apicoectomy.
- Conditions
- Periapical Periodontitis, Periradicular Lesion, Endodontic Treatment Failure, Postoperative Wound Healing
- Trial name
- NCT07734987
- Testing
- 3D-Printed Static Surgical Guide and Trephine Bur, Ultrasonic Retrograde Preparation and Bioceramic Retrograde Obturation
- Where
- Vietnam
- Volunteers
- 11 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Thyroid Disease
Platysma Trial - Platysma Suturing Versus no Sutures for Wound Closure After Primary Thyroid Surgery
Influence of the platysma suture on postoperative pain and wound healing.
- Trial name
- Platysma (NCT02951000)
- Testing
- platysma suture, no platysma suture
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Tuebingen
Postoperative Wound Healing After Oral Cancer Surgery
Topical Phenytoin-Loaded Hydrogel Dressing for Postoperative Wound Management After Oral Squamous Cell Carcinoma Resection
This randomized, parallel-arm clinical trial evaluated whether a topical phenytoin-loaded hydrogel dressing could improve postoperative wound healing in patients undergoing surgical resection and reconstruction for locally…
- Trial name
- NCT07801157
- Testing
- Topical Phenytoin-Loaded Hydrogel Dressing, Conventional Postoperative Wound Care
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Mansoura University
Head and Neck Cancer
Pre- and Postoperative Nutrition in Head and Neck Cancer Patients
The purpose of the project is to investigate the effect of wound healing of a combined pre- and postoperative oral supplement, consisting of zinc, vitamin C, arginine and multivitamin, as a supplement for adequate nutrition in…
- Trial name
- NCT03531190
- Testing
- Nutritional supplement (Protein + MIX), Nutritional supplement (Protein)
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- University of Copenhagen
Cesarean Section Wound, Platelet-rich Plasma (PRP)
Efficacy of Platelet-rich Plasma in Improving Postoperative Scarring After Cesarean Delivery
Cesarean section often leads to postoperative scarring, which can impact both physical and psychological well-being. Platelet-rich plasma (PRP), rich in growth factors, is used in regenerative medicine to promote healing and…
- Conditions
- Cesarean Section Wound, Platelet-rich Plasma (PRP), Regenerative Medicine
- Trial name
- PRP06081992 (NCT06978010)
- Testing
- Platelet-Rich Plasma (PRP) intraoperatively
- Where
- Romania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint Andrew Hospital Constanta
Wound Healing, Wound Healing Complication
Sutureless Versus Conventional Suturing in Oral Surgery
This randomized clinical study compares sutureless wound closure using n-butyl-2-cyanoacrylate tissue adhesive with conventional silk suturing following minor oral surgical procedures.
- Conditions
- Wound Healing, Wound Healing Complication, Postoperative Pain, Oral and Maxillofacial Surgery Complications
- Trial name
- NCT07856524
- Testing
- Sutureless Wound Closure Using n-Butyl-2-Cyanoacrylate, Conventional Suturing
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- Jouf University
Impacted Mandibular Third Molar
Cyanoacrylate Adhesive in Impacted Mandibular Third Molars Surgery
The goal of this randomized clinical trial is to evaluate whether cyanoacrylate tissue adhesive can improve postoperative outcomes compared with conventional silk sutures in patients undergoing surgical removal of impacted…
- Trial name
- NCT07445724
- Testing
- cyanoacrylate tissue adhesive, Silk Sutures
- Where
- 2 sites in Vietnam
- Volunteers
- 23 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Wound Healing, Patient Comfort
Aquacel Compared to Traditional Post Surgical Wound Dressing in Vascular Surgery Patients
The study is a prospective randomised, controlled study of 136 patients undergoing vascular surgery. Their closed wounds were covered with either aquacel, a hydrofiber dressing, or a traditional gauze dressing.Number of changes…
- Trial name
- NCT00428623
- Testing
- wound dressing
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
GastroEsophageal Cancer
A Systems Approach to Immunotherapy Biomarker Identification Within the Postoperative Wound-Healing Microenvironment in Patients With Gastroesophageal Cancer
The purpose of this research is to collect surgical drain fluid and blood from patients who have undergone surgery for gastric or esophageal cancer, and to analyze the fluid and blood using a variety of laboratory techniques for…
- Trial name
- BAISIC (NCT05338060)
- Testing
- prospective collection of surgical exudates (SEs)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Inova Health Care Services