Clinical trials: Post-stroke
Healthy
From FAST to FAST BEE - Video-Based Stroke Mnemonic Pilot
This online study evaluates immediate learning outcomes after viewing a short animated FAST BEE stroke-education video (1 minute 51 seconds).
- Trial name
- FAST BEE (NCT07440602)
- Testing
- FAST BEE Stroke Education Video (1 minute 51 seconds)
- Where
- India
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Jubilee Mission Medical College and Research Institute
Stroke, Acute, Neuroprotection
Effectiveness and Biological Mechanism of Direct Ischemic Post-conditioning for Acute Stroke Patients Due to Large Vessel Occlusion
The goal of this clinical trial is to determine if direct ischemic post-conditioning (IPostC) can alleviate ischemic-reperfusion injury (I/R) in patients who have undergone endovascular thrombectomy (EVT).
- Conditions
- Stroke, Acute, Neuroprotection, Ischemic Conditioning
- Trial name
- NCT06545734
- Testing
- Direct Ischemic Post-conditioning, Endovascular therapy
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tianjin Huanhu Hospital
Stroke
HAptic Neurofeedback Design for Stroke
Interventional study with minimal risks and constraints, prospective, monocentric.
- Trial name
- HANDS (NCT04130711)
- Testing
- Visual virtual Conditions, Standard EEG, Neurofeedback Training Stroke Patients
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Stroke, Spasticity, Muscle
Analysis of the Correlation Between Ultrasound Imaging and Functional Parameters in the Medial Gastrocnemius Muscle in Post-stroke Patients With Spasticity in the Lower Limb
The goal of this observational study is to understand the impact of spasticity on muscle changes and functional performance in stroke patients with lower limb spasticity in comparison to non-stroke individuals.
- Trial name
- US-function (NCT06411587)
- Testing
- Ultrasound imaging and functional assessment
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Chronic Stroke
Effect of Somatosensory Motor Intergration Training on Post-stroke Upper Limb Function.
Background: Most patients suffer from post-stroke somatosensory and motor impairments, and 50% to 70% of patients in the chronic stage still have upper extremity impairments that severely limit their functional independence and…
- Trial name
- NCT06057584
- Testing
- somatosensory-motor integration training, pure somatosensory training, pure motor training
- Where
- Taiwan
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stroke
Reliability and Validity Study for SWE of Shoulder Muscles in Persons After Stroke.
This study aims 1. To examine the reliability of SWE assessment in the shoulder muscles of persons after a stroke. 2. To assess if differentiation can be made between the hemiplegic (HP) and non-hemiplegic (NHP) side and between…
- Trial name
- SWE_stroke (NCT04581551)
- Testing
- SWE assessor 1, SWE assessor 2, Stretch intervention
- Where
- 2 sites in Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Postoperative Cognitive Dysfunction, Cerebrovascular Accident
Neurological Outcome After Minimal Invasive Coronary Artery Bypass Graft
Primary objectives: Assessment of the incidence of postoperative cognitive dysfunction (POCD), cerebrovascular accident (CVA), and delirium after minimal invasive coronary artery bypass grafting (Endo-CABG).
- Conditions
- Postoperative Cognitive Dysfunction, Cerebrovascular Accident, Delirium
- Trial name
- NOMICS (NCT02979782)
- Testing
- Endo-CABG, PCI
- Where
- 2 sites in Belgium
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Stroke
Mechanisms of Walking Recovery After Stroke
Subjects with stroke will have behavioral testing and brain imaging before and after a 4-week control period and a 4-week exercise intervention.
- Trial name
- NCT02858349
- Testing
- No intervention, High-intensity interval training
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Subacute Stroke
Rehabilitation Robotics After a Stroke
Upper limb motor control after a stroke may be improved with rehabilitation robotics at a subacute stage. The aim of this multicenter controled randomized single blind study is to define the place of rehabilitation robotics at…
- Trial name
- REM_AVC (NCT01383512)
- Testing
- ARMEO Spring, Self rehabilitation
- Where
- 23 sites in France
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Atrial Fibrillation, Stroke
Anticoagulation With Rivaroxaban in Cardioversion -The ARC Study
The purpose of this study is to determine that a new drug called "Rivaroxaban®" is effective in preventing patients from forming clots after their heart rhythm has been reset by the cardiologist with an electrical device.
- Conditions
- Atrial Fibrillation, Stroke, Thrombo-embolism, Bleeding
- Trial name
- ARC (NCT01747746)
- Testing
- Rivaroxaban, Warfarin and Enoxaparin
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cook County Health
Stroke, Exercise
The Influence of Exercise on Neuroplasticity and Motor Learning After Stroke
Participants will complete 11 sessions. These include screening, 5 sessions where exercise or rest (according to group assignment) are paired with practice of a motor task, MRI and Transcranial Magnetic Stimulation (TMS) before…
- Conditions
- Stroke, Exercise, Rest
- Trial name
- EX-ML3 (NCT02980796)
- Testing
- Exercise, Practice
- Where
- Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cerebral Vascular Accident
Evaluation of the Benefit of the Training of the Manual Dexterity Post Stroke.
Stroke is the second leading cause of death and disability in France: more than half of stroke survivors have a disabling motor deficit, affecting mainly the upper limb.
- Trial name
- DEXTRAIN (NCT03934073)
- Testing
- DEXTRAIN, CONVENTIONNELLE, CONTROLE
- Where
- France
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Stroke, Split-belt Treadmill
Optimizing Gait Symmetry After Stroke Using Mechanical Constraints and Sensory Feedback
This single-session study aims to evaluate a novel gait training protocol that integrates mechanical constraints and sensory feedback to enhance paretic leg propulsion in individuals post-stroke.
- Conditions
- Stroke, Split-belt Treadmill, Resistance Exercise, Feedback
- Trial name
- NCT07087769
- Testing
- Treadmill Walking with Split-Belt and/or Tied-Belt Conditions, Mechanical Resistance (Pelvis and/or Ankle) depending on participant's walking capacity, Sensory Feedback Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Stroke
Evaluation of BOTOX® With Rehabilitation Therapy for the Treatment of Wrist and Hand Spasticity in Post-Stroke Patients
The present study is designed to determine the safety and effectiveness of injections of BOTOX® in spastic muscles of the arm and hand compared with injections of saline (which would do nothing) when combined with rehabilitation…
- Trial name
- Botox/Rehab (NCT00565201)
- Testing
- Botox and rehab
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Emory University
Hemorrhagic Stroke, Hemiparesis
Dual Transcranial Direct Current Stimulation (dTDCS)-Enhanced Therapy After Hemorrhagic Strokes and VEGF
This study will evaluate the feasibility of dual tDCS to improve arm motor function in chronic stroke patients. In addition it will collect pilot data on the blood biomarkers associated with treatment effect.
- Trial name
- NCT03857243
- Testing
- dual transcranial direct current stimulation
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Stroke Sequelae, Movement Disorders
Programmed Flexor-extensor Alternating Electrical Acupiont Stimulation on Limb Functional Reconstruction After Stroke
The purpose of this study is to study the effect mechanism of programmed flexor-extensor alternating electrical acupiont stimulation on upper limb functional reconstruction after stroke.
- Trial name
- NCT05333497
- Testing
- the fourth programmed generation of low-frequency acupoint electric stimulation therapy instrument, the fourth generation of low-frequency acupoint electric stimulation therapy instrument
- Where
- China
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Yang Liu
Stroke
Study of Neurophysiological Markers of Motor Recovery in Post-stroke Patients.
The aim of the study was to explore potential pathways for recovery and adaptation of neural pathways after stroke by examining electrical activity of the brain cortex and cortico-spinal excitability using transcranial magnetic…
- Trial name
- NCT06386627
- Testing
- Stimulus response task, Transcranial magnetic stimulation
- Where
- Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Acute Ischemic Stroke, Cerebral Edema
The Tolerability, Safety, and PK Characteristics of SIM1910-09 in Healthy Chinese Volunteers
This is a single-center, randomized, double-blind, placebo-controlled Phase I clinical study to evaluate the tolerability, safety, and pharmacokinetic characteristics of SIM1910-09 for injection after single/multiple dosing in…
- Trial name
- NCT05200728
- Testing
- SIM1910-09
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Jiangsu Simcere Pharmaceutical Co., Ltd.
Stroke
Brain Vital Signs M-Score: Point-of-care Monitoring for Motor Recovery After Stroke
The purpose of this study is to investigate brain signals relating to motor function, using electroencephalography (EEG) technology. The aims of the study can be separated into 3 specific study objectives: 1.
- Trial name
- NCT03858699
- Testing
- Recording of electroencephalographic (EEG) data
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- HealthTech Connex Inc.
Stroke
The Assessment of Knee Joints Function in People After Stroke
The study aims to assess the function of knee joints in patients after stroke compared to healthy people and evaluate the impact of rehabilitation on the function of knee joints in people after stroke.
- Trial name
- NCT06746493
- Testing
- Rehabilitation
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences