Clinical trials: Post-stroke Aphasia
Stroke, Aphasia
Transcranial Alternating Current Stimulation in Post Stroke Aphasia Therapy
This study aims to investigate the efficacy of transcranial alternating current stimulation (tACS) combined with linguistic training for patients with chronic post-stroke aphasia.
- Trial name
- AfatES (NCT07510464)
- Testing
- active 75 Hz transcranial alternating current stimulation
- Where
- Poland
- Volunteers
- 11 people
- Sponsor
- QVITI S.A.
Aphasia, Aphasia, Anomic
Speech Therapy and Repetitive Transcranial Magnetic Stimulation Therapy in Post-stroke Anomic Aphasia
The aim of the study is to observe the effects of speech therapy and transcranial magnetic stimulation therapy in patients who develop anomic aphasia after stroke.
- Conditions
- Aphasia, Aphasia, Anomic, Stroke
- Trial name
- NCT04625790
- Testing
- Repetitive transcranial magnetic stimulation, Speech therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Ege University
Stroke
Transcranial Direct Current Stimulation for Post-Stroke Aphasia
This is a randomized, crossover design trial that will compare how anodal transcranial direct current stimulation (tDCS) versus sham tDCS administered during multiple sessions of scripting therapy affects the acquisition and…
- Trial name
- NCT02461355
- Testing
- Aphasia therapy, Anodal tDCS
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Columbia University
Aphasia, Stroke
Levetiracetam (Keppra) to Improve Chronic Aphasia in Post-stroke Patients.
The study investigates the possibility that levetiracetam may improve the symptoms of chronic post-stroke aphasia.
- Trial name
- NCT00227461
- Testing
- Wait first, then levetiracetam, Levetiracetam first, then wait
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Kessler Foundation
Aphasia, Stroke
fMRI of Language Recovery Following Stroke in Adults
The purpose of this study is to test the effectiveness of constraint-induced aphasia therapy.
- Trial name
- NCT00843427
- Testing
- CIAT
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Alabama at Birmingham
Aphasia, Chronic Stroke
Transcutaneous Vagus Nerve Stimulation in Aphasia After Stroke
Aphasia is an acquired language disorder. Stroke is the most common cause of aphasia, which affects 30% of stroke survivors. Speech and Language Therapy (SLT) can help people with aphasia but it may not be provided at the…
- Trial name
- TRANSLATE (NCT06403475)
- Testing
- Transcutaneous Vagus Nerve Stimulation, Computer Based Speech and Language Therapy (Step by Step)
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Aphasia, Stroke
Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia
The goal of this clinical trial is to determine if Transcranial Magnetic Stimulation (TMS) combined with Speech-Language Therapy (SLT) is an effective treatment for mild aphasia in persons with chronic stroke.
- Conditions
- Aphasia, Stroke, Aphasia Following Cerebral Infarction, Aphasia, Acquired
- Trial name
- TMS (NCT06842745)
- Testing
- Transcranial Magnetic Stimulation (TMS), Speech-Language Therapy (SLT)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pennsylvania
Stroke, Aphasia
Comparison of Therapeutic Effect Between Speech Rehabilitation Program and Speech Therapy in Stroke Patients With Aphasia
Our study will provide precise and intensive speech rehabilitation treatment program to patients with speech disorders after stroke, and compare clinical evaluations with the conventional speech therapy patient group.
- Conditions
- Stroke, Aphasia, Speech Therapy
- Trial name
- NCT06361901
- Testing
- Zenicog;language rehabilitation program, Conventional language rehabilitation
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Korea University Guro Hospital
Aphasia, Stroke
Home Program Practice for People With Language Disorders After Stroke
Logbooks are one of the most commonly used methods to both support and track adherence in research studies. This study will look at using logbooks to support adherence to reading practice for individuals with post-stroke aphasia.
- Trial name
- NCT04543084
- Testing
- Logbook
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Duquesne University
Aphasia, Acquired, Stroke
Rehabilitation of Post-stroke Aphasia by Targeting Phonological, and Lexico-semantic Deficits With Speech Output Tasks
Aphasia in brain-damaged adult patients refers "to the more or less complete loss of the ability to use language" resulting from acquired brain damage, typically of the left hemisphere.
- Conditions
- Aphasia, Acquired, Stroke, Anomia
- Trial name
- PHOLEXSEM (NCT06451731)
- Testing
- PHOLEXSEM, PACE
- Volunteers
- 44 people
- Sponsor
- Istituto Auxologico Italiano
Aphasia Non Fluent, Stroke
Sensory-Motor Integration for Speech Rehabilitation in Patients With Post-stroke Aphasia
SEMO is a multidisciplinary project (language sciences, cognitive psychology and neuropsychology, physical medicine and rehabilitation, neurology, speech-language pathology, functional neuroimaging and engineering sciences) that…
- Trial name
- SEMO (NCT04433351)
- Testing
- Enriched rehabilitation, Simple rehabilitation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Grenoble
Aphasia, Chronic Stroke
A Trial Investigating Telerehabilitation as an add-on to Face-to-face Speech and Language Therapy in Post-stroke Aphasia.
The aim of this study is to investigate the effects of high-frequency short duration tablet-based speech and language therapy (teleSLT) mixed with cognitive training (teleCT) in chronic stroke patients.
- Conditions
- Aphasia, Chronic Stroke, Post Stroke Seizure
- Trial name
- NCT03228264
- Testing
- teleSLT, teleCT
- Where
- 2 sites in Switzerland
- Volunteers
- 21 people
- Sponsor
- University of Bern
Post-stroke Aphasia, PSA
Effectiveness of Electroacupuncture at Xuanzhong (GB39) and Tongli (HT5) Points in Post-Stroke Aphasia
Post-stroke aphasia (PSA) is a prevalent and debilitating condition that significantly impairs communication, social participation, and quality of life, often leading to increased long-term healthcare costs and psychological…
- Trial name
- NCT07684781
- Testing
- Electroacupuncture, Basic treatment + Speech therapy
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Stroke, Ischemic, Aphasia
pBFS-guided cTBS Combined With iTBS Over the Superior Frontal Gyrus for Aphasia After Ischemic Stroke
The current study aims to evaluate the efficacy and safety of pBFS-guided cTBS combined with iTBS for the rehabilitation of language functions in patients with post-ischemic stroke aphasia.
- Trial name
- NCT06086938
- Testing
- active cTBS combined with iTBS
- Volunteers
- 40 people
- Sponsor
- Changping Laboratory
Post-stroke Depression, Post-stroke Aphasia
Impact of Intensive Social Interaction on Post-Stroke Depression in Individuals With Aphasia
The present parallel-group, single-center, blinded-assessment controlled trial seeks to explore the feasibility - in terms of high completion rates - and potential efficacy of intensive communicative-pragmatic social interaction…
- Trial name
- CONNECT (NCT04318951)
- Testing
- Intensive communicative-pragmatic social interaction., Standard care.
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Medicine Greifswald
Stroke, Ischemic, Aphasia
pBFS-guided iTBS Over the Superior Temporal Gyrus for Aphasia After Ischemic Stroke
The objective of this trial is to evaluate the effectiveness and safeness of intermittent Theta Burst Stimulation (iTBS) over the left Superior Temporal Gyrus (STG), guided by personalized Brain Functional Sector (pBFS)…
- Trial name
- NCT05929534
- Testing
- active intermittent Theta Burst Stimulation
- Volunteers
- 40 people
- Sponsor
- Changping Laboratory
Stroke
Effects of Cerebrolysin on Language Ability in Non-fluent Aphasia Patients After Stroke: A Randomized, Placebo-controlled, Double-blinded, Single Center Study
" This study aims to measure changes in language ability after adding cerebrolysin to standard treatment for non-fluent aphasia patients with post-stroke language impairment.
- Trial name
- NCT06897176
- Testing
- Cerebrolyisin
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Aphasia Following Cerebral Infarction
TDCS and Aphasia Therapy in the Acute Phase After Stroke
This study evaluates the neuromodulatory effect of combined tDCS and aphasia therapy in patients in the acute stage after stroke.
- Trial name
- NCT03297450
- Testing
- tDCS, Aphasia therapy
- Where
- Belgium
- Volunteers
- 1 people
- Sponsor
- University Hospital, Ghent
Aphasia, Stroke, Acute
Tablet-based Aphasia Therapy in the Acute Phase After Stroke
As aphasia is one of the most common and disabling disorders following stroke, in many cases resolving in long-term deficits, it is now thought that intensive aphasia therapy is effective, even in the chronic phase following…
- Trial name
- NCT03679637
- Testing
- Tablet-based aphasia therapy
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- University Hospital, Ghent
Aphasia, Language
tDCS as an Adjuvant to Intensive Speech Therapy for Chronic Post Stroke Aphasia
The purpose of this study is to determine if transcranial direct current stimulation (tDCS) in conjunction with intensive speech therapy will improve sentence production and word retrieval in individuals with chronic post stroke…
- Trial name
- NCT02801864
- Testing
- Real tDCS, Intensive Speech Therapy
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Austin Speech Labs