Clinical trials: Post-surgical Wound Healing
Quality of Life, Biopsy Wound
Oral Biopsies: Evaluation of the Post-surgical Discomfort
Aim of this study is to evaluate the post-operative course in patients undergoing diagnostic or therapeutic oral mucosal biopsies.
- Conditions
- Quality of Life, Biopsy Wound, Surgical Wound, Healing Surgical Wounds
- Trial name
- NCT04514263
- Testing
- OHIP-14 Administration, VNS Administration
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Catholic University of the Sacred Heart
Cleft Palate
Efficacy of Oral Versus Intravenous Acetaminophen for Primary Pediatric Cleft Palate Repair
The purpose of this investigator-initiated study is to determine whether acetaminophen is an effective pain reliever for primary cleft palate repair in children and possesses opioid sparing effects.
- Trial name
- NCT01500109
- Testing
- Oral acetaminophen, Ofirmev®, Opioid only
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Loma Linda University
Thyroid; Wound, Parathyroid Diseases
Comparing the Impact of AMNIOEFFECT Application vs Standard of Care on Post-Operative Healing in Patients Who Have Undergone Thyroid and Parathyroid Surgery Via the Transcutaneous Approach
The purpose of this study is to understand how placing Amnioeffect on patients having transcutaneous thyroid or parathyroid surgery affects surgery scar appearance, pain, and the ability to swallow and compare it to patients who…
- Conditions
- Thyroid; Wound, Parathyroid Diseases, Surgical Incision, Incision
- Trial name
- NCT07173621
- Testing
- Amnioeffect
- Where
- United States
- Volunteers
- 334 people
- Sponsor
- Sarasota Memorial Health Care System
Subaortic Stenosis, Congenital Heart Disease
The Fate of Aortic Valve After SAS Surgery in Children
Aortic valve regurgitation (AR) is a common complication following surgery for subaortic stenosis (SAS), yet the long-term outcomes and risk factors for postoperative significant AR (SAR) remain poorly understood.
- Conditions
- Subaortic Stenosis, Congenital Heart Disease, Aortic Regurgitation
- Trial name
- NCT06751368
- Where
- China
- Volunteers
- 232 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Aneurysm
Cryoablation of Intercostal Nerves for Better Control of Postoperative Pain After Thoracic and Thoracoabdominal Open Surgery
The purpose of the registry is to evaluate the peri-operative and short- term outcomes of intercostal nerves cryoablation for post-operative pain control after open thoracic and thoracoabdominal aortic aneurysms repair.
- Trial name
- NCT05153083
- Testing
- Open thoracic (TAA) and thoracoabdominal aortic aneurysms repair (TAAA)
- Where
- 13 sites in Austria, France and 6 more
- Volunteers
- 200 people
- Sponsor
- Germano Melissano
ACL Injury, ACL Tears
Extended Oral Tranexamic Acid After Anterior Cruciate Ligament Reconstruction
This is a prospective, multi-center, randomized, double-blind, placebo-controlled trial evaluating the efficacy of oral tranexamic acid (TXA) in improving postoperative outcomes following anterior cruciate ligament reconstruction…
- Conditions
- ACL Injury, ACL Tears, ACL Surgery
- Trial name
- NCT07115056
- Testing
- Tranexamic Acid (TXA)
- Where
- 6 sites in United States
- Sponsor
- Campbell Clinic
Obese
Pre-operative Diet: Effect of Wound Healing After Bariatric Surgery
This study is a randomised control trial comparing the effects of a pre-operative very low calorie diet (VLCD) on wound healing in the morbidly obese patients undergoing bariatric surgery.
- Trial name
- NCT01950052
- Testing
- Diet group 800 Kcal diet
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- King's College Hospital NHS Trust
Thyroid Neoplasms, Thyroid Carcinoma
Influence of Thyroid Hormones on the Woundhealing Process
Main goal of this clinical investigation is to investigate different cytokines in wound fluids of euthyroid vs. hypothyroid patients. As a primary endpoint we want to evaluate if different cytokine levels in euthyroid vs.
- Trial name
- NCT00929318
- Testing
- blood sampling
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- Hannover Medical School
Hernia, Inguinal, Hernia, Femoral
Chronic Pain After Groin Hernia Repair
In the present study the investigators aimed to investigate the relationship between surgical methods and chronic pain in over 20 000 patients who underwent groin hernia repair in Sweden
- Trial name
- NCT02751190
- Testing
- Totally ExtraPeritoneal (TEP) repair, TransAbdominal PrePeritoneal (TAPP) repair, Open anterior mesh repair
- Volunteers
- 24,607 people
- Sponsor
- Umeå University
Scoliosis Patients
Feasibility, Acceptability, and Preliminary Effects of Virtual Reality for Pain, Anxiety and Recovery Enhancement of Children Post-scoliosis Surgical Repair
Adolescent idiopathic scoliosis is the most common spinal deformity in adolescents and frequently requires surgical intervention when curvature becomes severe.
- Trial name
- VR-SPINE (NCT07737886)
- Testing
- Virtual Reality, Standard medical treatment
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- St. Justine's Hospital
Pain, Acute, Pain, Postoperative
The Impact of Esmolol Administration on Postoperative Recovery
The aim of this study will be to investigate the effect of a continuous infusion of low dose esmolol on intraoperative and postoperative opioid consumption, as well as on postoperative recovery and chronic pain
- Conditions
- Pain, Acute, Pain, Postoperative, Pain, Chronic Post-Surgical, Esmolol
- Trial name
- esmolol (NCT05567822)
- Testing
- Esmolol Hydrochloride, normal saline
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- Aretaieion University Hospital
Mitral Valve Repair Surgery
Mitral Valve Area Using 3-dimensional Transesophageal Echocardiography
Even during mitral valve repair procedure (MVP) for severe mitral stenosis (MS), the intraoperative assessment of mitral valve area (MVA) is necessary for evaluating the severity of MS before the repair and excluding residual MS…
- Trial name
- MVA (NCT01694251)
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Konkuk University Medical Center
ACL Injury
Dietary Protein Intake and Rehabilitation From Anterior Cruciate Ligament Surgery
Protein supplementation may promote increases in strength and hypertrophy in the context of resistance training (RT) and reduce markers of inflammation, while sufficient levels of protein are necessary for healing certain wounds…
- Trial name
- NCT03614351
- Testing
- Protein (PROT), Control (CONT)
- Sponsor
- Wake Forest University Health Sciences
Ankle Injuries, Fracture
Rest Easy: Is Bed Rest Really Necessary After Surgical Repair of an Ankle Fracture?
After a patient has fractured an ankle that then requires surgery, the recommendation is to remain in bed, with the operated leg elevated on pillows for 48 hours.
- Trial name
- NCT00690651
- Testing
- Early mobilization, Standard mobilization
- Where
- Australia
- Volunteers
- 104 people
- Sponsor
- The Alfred
Breast Tumors, Wound Healing
HealiAid Collagen Wound Dressing in Patients Undergoing Breast Tumor Surgery
The goal of this clinical trial is to evaluate the safety of the collagen wound dressing (HealiAid) in breast tumor patients with surgical treatment. The main questions it aims to answer are: 1.
- Conditions
- Breast Tumors, Wound Healing, Collagen Wound Dressing
- Trial name
- NCT07209020
- Testing
- HealiAid Collagen Wound Dressing
- Where
- 3 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- Maxigen Biotech Inc.
Sternal Injury, Cardiac Surgery
Improving Sternal Healing After Cardiac Surgery: Sternal Wire vs ZIPFIX
The objective of this study is to determine whether sternal reconstruction using the ZIPFIX system compared to standard wire cerclage could improve bone healing, patient function, and decreased postoperative pain.
- Conditions
- Sternal Injury, Cardiac Surgery, Heart Diseases
- Trial name
- Closure (NCT03289104)
- Testing
- Steel Wires, ZipFix Sternal Closure System
- Where
- Canada
- Sponsor
- Ottawa Heart Institute Research Corporation
Wound Heal, Diabetic Foot Ulcer
Effect of New High Ankle Block on Wound Healing After the Operation of Debridement of Diabetes Foot
The goal of this clinical trial is to compare high ankle block and general anesthesia on wound recovery and ankle blood flow perfusion after diabetes foot surgery in diabetics.
- Trial name
- NCT06395961
- Testing
- high ankle block, general anesthesia
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Xuzhou Central Hospital
Pain, Wound Healing Disturbance of
Periodontal Dressing After Surgical Crown Lengthening
Background: There is controversy regarding the postoperative effects of periodontal dressing on the periodontium, pain and discomfort.
- Conditions
- Pain, Wound Healing Disturbance of, Periodontal Infection
- Trial name
- NCT01986959
- Testing
- With Periodontal dressing, Without Periodontal dressing
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Franciscan University Center
Frozen Shoulder, Rotator Cuff Tears
Preoperative Psychological Risk Factors for the Retractable Capsulitis of the Shoulder After Shoulder Rotator Cuff Repair Surgery
The main objective of our study is to determine whether preoperative anxiety, depression and kinesiophobia are risk factors for retractile capsulitis after arthroscopic rotator cuff repair to best support these patients.
- Trial name
- NCT04044196
- Testing
- Rotator cuff repair
- Where
- 2 sites in France
- Volunteers
- 77 people
- Sponsor
- Hospital Ambroise Paré Paris
Hernia Repair, Hernia Inguinal
Postsurgical Analgesia After Hernia Repair
The study is designed to evaluate the safety, efficacy, and pharmacokinetics (PK) of three ascending doses of AMT-143 to determine the appropriate dose of AMT-143 for the management of postsurgical pain following inguinal hernia…
- Conditions
- Hernia Repair, Hernia Inguinal, Hernia Surgery, Hernia, Inguinal/Surgery
- Trial name
- NCT06709612
- Testing
- AMT-143, ropivacaine
- Sponsor
- AmacaThera Inc.