Clinical trials: Post-thoracotomy Pain
Postoperative Pain, Analgesia
Postoperative Analgesis for Pain Management After Thoracotomy
Thoracotomy is among the most painful surgical procedures and can cause severe pain. Postoperative pain causes many complications. Therefore, pain management is important in patients undergoing thoracotomy.
- Trial name
- NCT06177652
- Testing
- Paravertebral Block, Serratus Plane Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Kocaeli University
Pain, Postoperative, Intrathoracic Procedure
Cryoablation Effects on Acute and Chronic Pain After Thoracotomy and Thoracoscopy
The researchers will compare the common methods of post-surgical pain control, such as epidural or intercostal nerve block with a newer method called cryoablation.
- Trial name
- NCT06384664
- Testing
- Atricure's crysoSPHERE probe, Standard of Care
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Post-thoracotomy Pain
Does Peri-Operative Gabapentin Reduce Chronic Post-Thoracotomy Pain?
The primary objective of this study is to determine if gabapentin can decrease or prevent chronic post-thoracotomy pain.
- Trial name
- NCT00934193
- Testing
- Gabapentin
- Sponsor
- University of Kansas Medical Center
Pain Following Thoracotomy Surgery
Study of Exparel Versus Epidural for Pain Control After Thoracotomy
Unilateral intercostal nerve blocks provide pain control as effectively as a continuous thoracic epidural, and will a lower incidence of side effects.
- Trial name
- NCT02178553
- Testing
- Epidural, Intercostal Bupivicaine (Exparel)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Mayo Clinic
Postoperative Pain
NSAIDs With Morphine-PCA Compared to Epidural Analgesia in Thoracotomy Pain
The investigators investigated whether a strictly controlled pain management with patients participating in a clinical study can attenuate persistence of post-thoracotomy pain.
- Trial name
- NCT01541137
- Testing
- Diclofenac, parecoxib/ valdecoxib, patient controlled epidural analgesia
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Helsinki University Central Hospital
Postoperative Pain, Thoracic Surgery
Intravenous Lidocaine, Ketamine, and Magnesium in Thoracic Surgery
Thoracic surgery often produces severe postoperative pain due to nerve injury and inflammation. Effective pain control is essential to reduce complications and opioid use.
- Conditions
- Postoperative Pain, Thoracic Surgery, Multimodal Analgesia, Opioid Consumption, Postoperative
- Trial name
- LKM-Thorax (NCT07359469)
- Where
- Spain
- Volunteers
- 118 people
- Sponsor
- Universidad Pública de Navarra
Post Operative Pain, Thoracotomy
Kinesiology Taping After Thoracotomy
Effective pain control after thoracotomy increases the patient's respiratory functions and related quality of life, reduces the length of hospital stay and the amount of analgesia use.
- Conditions
- Post Operative Pain, Thoracotomy, Pulmonary Function
- Trial name
- Taping (NCT05617235)
- Testing
- Kinesiology taping
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Akdeniz University
Persistent Pain, Postoperative Hyperalgesia
Prevention of Persistent Postsurgical Pain After Thoracotomy
Postthoracotomy acute pain is followed by persistent postsurgical pain in 20-30% of the patients, defined as pain that lasts more than 3-6 months after surgery.
- Trial name
- NCT01243801
- Testing
- Ketamine
- Where
- 2 sites in Spain
- Volunteers
- 104 people
- Sponsor
- Hospital Clinic of Barcelona
Post-operative Pain, Thoracic Epidural
Dexmedetomidine and Fentanyl as Adjuvants to Thoracic Epidural
To find out if there is a benefit from adding dexmedetomidine to epidural bupivacaine as regards: Intra and postoperative opioid consumption Pain score (numerical rating scale) Hemodynamic stability, Patient satisfaction.
- Conditions
- Post-operative Pain, Thoracic Epidural, Thoracotomy Surgery
- Trial name
- adjuvants (NCT06489574)
- Testing
- thoracic epidural with dexmedetomidine in patients undergoing thoracotomy surgery, thoracic epidural with fentanyl in patients undergoing thoracotomy surgery
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative, Surgery, Thoracic
Influence of Preoperative Support on Anxiety, Pain and Satisfaction With Postoperative Analgesia
The aim of this study was to analyze a relationship between information support provided by an interdisciplinary team and the levels of anxiety, pain and satisfaction with postoperative analgesia in children and adolescents…
- Trial name
- NCT03488459
- Testing
- Routine preoperative information from a nurse, Additional information support from a psychologist
- Where
- Poland
- Volunteers
- 112 people
- Sponsor
- National Institute for Tuberculosis and Lung Diseases, Poland
Pain, Postoperative Period
Ketamine Combination With Spinal Morphine for Post Thoracic Surgery Pain : A Randomized Control Study
Thoracotomy is one of the most painful operation. Continuous thoracic epidural or paravertebral analgesia are gold standard for postoperative pain. But both techniques require skills.
- Trial name
- NCT02570230
- Testing
- NSS, Ketamine
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Mahidol University
Atrial Fibrillation, Neuropathic Pain
Atrial Fibrillation and Neuropathic Pain After Thoracotomy and Continuous Application of Magnesium Sulphate.
Atrial fibrillation and chronic neuropathic pain are adverse events occurring after posterolateral thoracotomy for lung resection. The continuous application of magnesium sulphate may have a prophylactic effect.
- Trial name
- NCT02008747
- Testing
- Magnesium sulphate
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Chronic Postoperative Pain
Does a Multimodal no-Compression Suture Technique of the Intercostal Space Reduce Chronic Post-Thoracotomy Pain?
Chronic post-thoracotomy pain is a significant adverse outcome of thoracic surgery. transcollation technology evaluated with a prospective randomized trial the effect of a multimodal no-compression suture technique of the…
- Trial name
- NCT02630849
- Testing
- intercostal muscle flap and pericostal no-compression suture, Standard suture technique of the intercostal space
- Volunteers
- 380 people
- Sponsor
- University of Roma La Sapienza
Ketamine, Adjuvant
Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain
The aim of this study is to evaluate the role of ketamine as an adjuvant in external oblique intercostal plane block for post thoracotomy pain.
- Conditions
- Ketamine, Adjuvant, External Oblique Intercostal Plane Block, Thoracotomy
- Trial name
- NCT07138781
- Testing
- Ketamine, 29 ml bupivacaine 0.25% + 1 ml saline
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Magnesium Sulphate, Post Pulmonary Resection
Magnesium Infusion for Pain Relief After Thoracotomy. A Randomized Controlled Trial.
All patients were premedicated with oral midazolam 5-15 mg. one hour before surgery. General anesthesia with double lumen endobronchial tube was given. Patient was induced by propofol and fentanyl.
- Conditions
- Magnesium Sulphate, Post Pulmonary Resection, Pain
- Trial name
- NCT01261702
- Testing
- magnesium sulphate
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Mahidol University
Pain, Shoulder, Postoperative Pain
The Effects of Qigong Exercise Training After Thoracotomy
Postoperative pulmonary complications after thoracotomy cause morbidity and mortality. Although the causes of postoperative pulmonary complication are multifactorial, respiratory muscle dysfunction is a contributing factor to the…
- Conditions
- Pain, Shoulder, Postoperative Pain, Joint Adhesion, Muscle Weakness
- Trial name
- NCT05470192
- Testing
- Qigong exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Akdeniz University
Thoracotomy Surgery, Anesthesia
Ultrasound-guided PVB
Thoracotomy, is a surgical procedure performed routinely in connection with pulmonary surgery. Pain induced by thoracotomy is considered as the most severe post-operative pain.
- Conditions
- Thoracotomy Surgery, Anesthesia, Ultrasound-guided PVB, Post-operative Pain
- Trial name
- BPV échoguidé (NCT01842698)
- Testing
- ultrasoundguided paravertebral catheter
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Jean Perrin
Dexmedetomidine, Adjuvant
Dexmedetomidine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain
This study aims to evaluate the role of dexmedetomidine as an adjuvant in external oblique intercostal plane block for post-thoracotomy pain.
- Conditions
- Dexmedetomidine, Adjuvant, External Oblique Intercostal Plane Block, Thoracotomy
- Trial name
- NCT06684535
- Testing
- Dexmedetomidine, Saline
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Pain, Postoperative
Flexibility of Cognition And Persistent Pain
This observational study aims to determine the association between preoperative cognitive flexibility and the risk of developing PPSP by preoperative administration of cognitive tests.
- Trial name
- FlexCAPP (NCT02579538)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Post-thoracotomy Pain Syndrome
Effects of Intravenous Acetaminophen in Patients Undergoing Thoracoscopic Surgery
This is a single-center, randomized, double-blind, placebo-controlled trial. A total of 100 patients, 50 per treatment arm, undergoing minimally invasive thoracic surgery will be randomized 1:1 across 2 treatment arms: Ofiramev®…
- Trial name
- IVTylenol (NCT03051932)
- Testing
- Ofiramev® (IV Acetaminophen)
- Sponsor
- The University of Texas Medical Branch, Galveston