Clinical trials: Post-traumatic
PTSD, Alcohol Use Disorder
Oxytocin to Enhance Integrated Treatment for AUD and PTSD
The primary objective of the proposed Stage II study is to examine the efficacy of oxytocin (OT) as compared to placebo in reducing (1) alcohol use disorder (AUD) symptoms, and (2) post-traumatic stress disorder (PTSD) symptoms…
- Trial name
- COPE+OT (NCT04523922)
- Testing
- 40 IU Intranasal Oxytocin, Concurrent Treatment of PTSD and Substance Use Disorders using Prolonged Exposure
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Medical University of South Carolina
Posttraumatic Stress Disorder
MDMA-Assisted Psychotherapy in People With Posttraumatic Stress Disorder
The goal of this clinical trial is to compare MDMA-assisted therapy to placebo with therapy in people with chronic, treatment-resistant posttraumatic stress disorder (PTSD).
- Trial name
- NCT00090064
- Testing
- Midomafetamine HCl, Therapy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Resilient Pharmaceuticals
Post-Traumatic Headache
Hypersensitivity to Phosphodiesterase 3 Inhibition in Post-Traumatic Headache
To investigate whether cilostazol (phosphodiesterase 3 inhibitor) induces headache with migraine-like features in people with persistent post-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI).
- Trial name
- NCT05595993
- Testing
- Cilostazol
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Danish Headache Center
PTSD, Panic Attacks
Exposure Therapy for Veterans With PTSD and Panic Attacks (Phase 1)
To evaluate the feasibility, acceptability and effectiveness of Multiple Channel Exposure Therapy-Veterans (MCET-V) as a treatment for returning service members with comorbid posttraumatic stress disorder (PTSD) and panic…
- Trial name
- NCT01551199
- Testing
- Multiple Channel Exposure Therapy- Veterans
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- VA Office of Research and Development
Stress Disorders, Post-Traumatic
Trial to Evaluate Efficacy of Magnetic Resonant Therapy (MRT) in PTSD
The purpose of this study is to establish the efficacy of Magnetic Resonant Therapy in treating Post Traumatic Stress Disorder in Veterans.
- Trial name
- NCT02268084
- Testing
- Magnetic EEG/ECG-guided Resonance Therapy
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Wave Neuroscience
Traumatic Brain Injury
Anosognosia Evaluation After Cranocerebral Trauma Moderate to Severe
This study is conducted over 18 months. The main objective of this study is to test and compare the relevance and reliability of different tools for measuring the anosognosia.
- Trial name
- ANOSOGNOSIA (NCT02333006)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Convergence Insufficiency, Traumatic Brain Injury
Eye Recovery Automation for Post Injury Dysfunction (iRAPID)
This study will test a portable virtual reality (VR) system with integrated eye tracking called Virtual Eye Rotation Vision Exercises (VERVE). The proposed VERVE platform will deliver vergence therapy in an automated manner.
- Conditions
- Convergence Insufficiency, Traumatic Brain Injury, Concussion, Mild
- Trial name
- iRAPID (NCT06105892)
- Testing
- Virtual Eye Rotation Vision Exercise (VERVE)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- New Jersey Institute of Technology
PTSD
Treatment of Pediatric Post-traumatic Stress Disorder With Memory Reactivation Under the Influence of Propranolol
By age 18, roughly 8% of traumatized youth have met criteria for a diagnosis of PTSD, with numbers rising up to 40% in cases of sexual abuse and assault.
- Trial name
- PPP (NCT04985344)
- Testing
- Propranolol Oral Product, memory reactivation
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Toulouse
Stress Disorders, Post-Traumatic
Train Your Brain: Neurofeedback Intervention for PTSD
The investigator's aim is to evaluate the efficacy of two types of neurofeedback treatments for PTSD symptoms reduction. Half of the participants will receive the current standard for PTSD neurofeedback care undergoing…
- Trial name
- NCT03858933
- Testing
- eBrainFit Platform
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Southern California
Post-Traumatic Stress Disorder
Trauma-focused Cognitive-behavioural Therapy(TF-CBT) for Children: A Study of Process and Outcome.
The purpose of this study is to determine whether Trauma focused cognitive behavioral therapy (TF-CBT)is more effective in the treatment of traumatized youth than treatment as usual(TAU).
- Trial name
- NCT00635752
- Testing
- TF-CBT, Treatment as Usual (TAU)
- Where
- Norway
- Volunteers
- 156 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Psychological Trauma, Stress Disorders, Post-Traumatic; Mental Disorders
Trauma-Focused Group Therapy for Adults With Trauma-Related Symptoms in Primary Care
Psychological trauma is common and can lead to long-lasting emotional distress, difficulties in daily functioning, and reduced quality of life.
- Trial name
- NCT07757334
- Testing
- Trauma-Focused Group Intervention, Treatment as Usual (TAU)
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Luis Eduardo Estévez Cachafeiro
Post Traumatic Stress Disorder, Depression
Cross-sectoral Collaboration in Multidisciplinary Treatment of Trauma-affected Refugees
INTRODUCTION Trauma-affected refugees are at high risk of developing mental health problems including post-traumatic stress disorder (PTSD) and depression.
- Conditions
- Post Traumatic Stress Disorder, Depression, Psychosocial Problem
- Trial name
- NCT04244864
- Testing
- Cross-sectoral psychosocial intervention, Treatment as usual (TAU)
- Where
- Denmark
- Volunteers
- 196 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Cerebral Stroke, Traumatic Brain Injury
Telerehabilitation Early After CNS Injury
The goal of this clinical trial is to assess the safety and feasibility of providing extra doses of rehabilitation therapy for persons with a recent stroke, traumatic brain injury (TBI) and/or spinal cord injury (SCI).
- Conditions
- Cerebral Stroke, Traumatic Brain Injury, Spinal Cord Injuries
- Trial name
- NCT06069999
- Testing
- HandyMotion Treatment Program
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- TRCare, Inc.
Concussion, Brain
A Wrist-Worn Nerve Stimulator for Remediating Persistent Post-Concussive Symptoms in Adolescents
The goal of this study is to test a wearable nerve stimulator in adolescents with persistent post-concussive symptoms. The main questions it aims to answer is whether the device will reduce clinical symptom burden, reduce…
- Trial name
- NCT05685121
- Testing
- Apollo Neuro
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of South Carolina
Mild Traumatic Brain Injury, Concussion, Mild
Return to Work After Mild Traumatic Brain Injury
Background: Patients with mild traumatic brain injury can to some extend experience long-term physical, cognitive, social and behavioral deficits, which have serious implications for employment trajectories and financial…
- Trial name
- NCT03214432
- Where
- Denmark
- Volunteers
- 38,372 people
- Sponsor
- University of Copenhagen
Depression, Anxiety
Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families
The proposed study draws on prior research to evaluate the feasibility, acceptability and explore preliminary effectiveness of Coffee and Family Education and Support, Version (CAFES2) using a pilot randomized type 1 hybrid…
- Conditions
- Depression, Anxiety, PTSD, Family Dynamics
- Trial name
- NCT06261463
- Testing
- CAFES2
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Illinois Chicago
PTSD, Sleep Disorders
Cooperative Studies Program #563 - Prazosin and Combat Trauma PTSD
Background: Posttraumatic stress disorder (PTSD) is a debilitating and disabling mental disorder that afflicts at least 25% of Veterans who have suffered life-threatening war zone trauma.
- Trial name
- PACT (NCT00532493)
- Testing
- prazosin
- Where
- 15 sites in United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorders
Eszopiclone for the Treatment of Posttraumatic Stress Disorder
The purpose of this study is to determine if eszopiclone relative to placebo (sugar pill) is effective and tolerable for people with posttraumatic stress disorder (PTSD)-related sleep disturbance.
- Trial name
- NCT01605253
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Rush University Medical Center
Stress Disorders, Post-Traumatic
Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV
The purpose of this study is to find out why patients with post-traumatic stress disorder (PTSD) have an increased risk for heart disease and high blood pressure later in life.
- Trial name
- ANG-P (NCT02560805)
- Testing
- Microneurography, Combat virtual reality video clip, Handgrip Exercise
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Emory University
Self-directed Violence, Post-traumatic Stress Disorder (PTSD)
Evaluating Treatments for Suicidal Veterans With PTSD
Posttraumatic Stress Disorder (PTSD) is a significant driver of suicide risk among Veterans, but there is a critical knowledge gap about how to treat PTSD among people at elevated risk for suicide.
- Trial name
- NCT05974631
- Testing
- Dialectical Behavior Therapy, Dialectical Behavior Therapy Prolonged Exposure protocol, Prolonged Exposure therapy
- Where
- 4 sites in United States
- Volunteers
- 125 people
- Sponsor
- VA Office of Research and Development
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