Clinical trials: Post-traumatic, open to volunteers
Acute Stress Reaction
Promoting Improved Functioning Among People Experiencing Stressful Situations
The iCOVER intervention was developed to rapidly restore functioning in individuals experiencing an Acute Stress Reaction (ASR). iCOVER is undergoing widespread adoption but has not been tested for efficacy.
- Trial name
- iCOVER (NCT06482567)
- Testing
- iCOVER, Physical Presence with Reassurance
- Where
- 5 sites in United States
- Volunteers
- 450 people
- Sponsor
- University of North Carolina, Chapel Hill
Perinatal Mental Health, Reproductive Behavior
Women's Reproductive Choices and Mental Health During Pregnancy and After Birth in Wartime Ukraine
The goal of this observational study is to learn how war affects reproductive decisions and perinatal mental health in Ukrainian women.
- Conditions
- Perinatal Mental Health, Reproductive Behavior, Women, Cohort Studies
- Trial name
- NCT07551934
- Testing
- Psychological Assessment, Routine Clinical Data Collection
- Where
- Ukraine
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Taras Shevchenko National University of Kyiv
PTSD, Post-traumatic Stress Disorder
Induction of Dreaming With EEG and Anesthesia for Post-traumatic Stress Disorder
The goal of this study is to test whether anesthesia-induced experiences can help alleviate symptoms of PTSD in an (1) open-label trial (Phase I) and (2) single-center double-blind, randomized, active-comparator (dose-controlled)…
- Trial name
- IDEA_PTSD (NCT06577636)
- Testing
- Propofol
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Stanford University
Anxiety
Transcranial Alternating Current Stimulation (tACS) for the Treatment of Anxiety in Veterans: An Open-Label Pilot Study
Transcranial alternating current stimulation (tACS) in a wearable brain stimulation device that delivers a low intensity, pulsed, alternating current via scalp electrodes.
- Trial name
- NCT07288008
- Testing
- Transcranial alternating current stimulator
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Birmingham VA Health Care System
Post Traumatic Stress Disorder
Stepped Care for Posttraumatic Stress Disorder Study
Less than 20% of people with PTSD receive any treatment. This study extends a program of research by the investigator focused on developing adaptive (stepped) interventions for PTSD.
- Trial name
- STEPPS (NCT06947538)
- Testing
- webSTAIR, WebSTAIR plus coaching, Clinician administered Brief STAIR
- Where
- United States
- Volunteers
- 428 people
- Sponsor
- Boston Medical Center
Major Depressive Disorder (MDD, Anxiety Disorder, Generalized
Serotonin Variants & Gut Microbiota in Mental Health
This observational pilot study investigates whether a broad panel of genetic variants relevant to the serotonin pathway (including serotonergic system, methylation cycle, intestinal barrier integrity, and inflammatory response…
- Conditions
- Major Depressive Disorder (MDD, Anxiety Disorder, Generalized, Stress Disorders, Post-Traumatic, Panic Disorder
- Trial name
- NCT07634458
- Testing
- SNP Genotyping and Gut Metagenomics
- Volunteers
- 30 people
- Sponsor
- Neurobiologix
Breast Cancer, Colon Cancer
A Manualized Post-Traumatic Growth Intervention for People With Cancer in Greece - IC-Growth
Cancer can be a very traumatic experience for the people affected and the majority of the psychological literature focuses on this.
- Conditions
- Breast Cancer, Colon Cancer, Head and Neck Cancers
- Trial name
- IC-Growth (NCT07108517)
- Testing
- IC-Growth ACT-Based Support Program
- Where
- Greece
- Volunteers
- 180 people
- Sponsor
- Centre for Research and Technology Hellas
Autonomic Nervous System Disease, Concussive Injury
Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms
Many combat veterans (c-Vs), service members (SMs) and civilians with mild traumatic brain injury (mTBI, also termed concussion) suffer from persistent post-concussion symptoms (PPCS) that degrade physical and cognitive…
- Conditions
- Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder
- Trial name
- NCT07071350
- Testing
- HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI)
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Virginia Commonwealth University
Elbow Stiffness, Elbow Pain
Comparative Effects of Mulligan Mobilization With and Without Myofascial Release Technique in Management of Post Traumatic Elbow Stiffness
The Randomize Clinical Trial will involve 30 participants with post traumatic elbow stiffness recruited from Madinah Teaching Hospital and Chiniot General hospital Faisalabad. Consecutive sampling technique will be used.
- Trial name
- NCT07598526
- Testing
- Group A (Mulligan Mobilization with Myofascial Release Technique), Group B (Mulligan Mobilization alone)
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Faisalabad
Brain Injury, Cognition
Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSD
Veterans with mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD) commonly experience cognitive impairments including attention and executive function deficits that interfere with their ability to engage…
- Conditions
- Brain Injury, Cognition, PTSD, Intervention
- Trial name
- NCT05380050
- Testing
- Goal Management Training plus Attention Training, Brain Health Workshop and National Geographic Movies
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress
Trauma Informed Goal Management Training With a "Support Person" Module for Individuals Impacted by Post-Traumatic Stress
The purpose of this study is to determine whether adding a Support-Person Module to Trauma-Informed Goal Management Training (TIGMT) can improve engagement and recovery among individuals who have experienced traumatic events and…
- Trial name
- TIGMT-Assist (NCT07797543)
- Testing
- Trauma-Informed Goal Management Training (TIGMT), Trauma Informed Goal Management Training - Assist (TIGMT-Assist)
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- McMaster University
Anxiety, Posttraumatic Stress Disorder
School-based Practices in Arts and Resilience for Kids
This proposal will implement and test feasibility and efficacy of school-based art therapy and yoga/mindfulness programming to reduce mental health disparities and foster resilience in youth.
- Conditions
- Anxiety, Posttraumatic Stress Disorder, Trauma
- Trial name
- SPARK (NCT06945497)
- Testing
- Art Therapy, Yoga/Mindfulness
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Wayne State University