Clinical trials: Post-traumatic
PTSD, Sleep Disorders
Cooperative Studies Program #563 - Prazosin and Combat Trauma PTSD
Background: Posttraumatic stress disorder (PTSD) is a debilitating and disabling mental disorder that afflicts at least 25% of Veterans who have suffered life-threatening war zone trauma.
- Trial name
- PACT (NCT00532493)
- Testing
- prazosin
- Where
- 15 sites in United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PTSD
Effectiveness of Trauma Management Therapy and Prolonged Exposure Therapy
The purpose of this requirement is to identify an effective exposure psychotherapy paradigm for the treatment of Post-Traumatic Stress Disorder (PTSD) in active duty service members and veterans by comparing different exposure…
- Trial name
- NCT04549493
- Testing
- Exposure Therapy
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Post Traumatic Stress Disorder, Psychiatric Issue
Predictive Factors of PTSD in Adults Admitted to an Emergency Service
After trauma or stress factor like death exposition, serious injuries or sexual violence, some patients may develop stress reaction characterized by the presence of various symptoms among different categories (reviviscence…
- Trial name
- ISSUE (NCT03615014)
- Testing
- Filling questionnaires
- Where
- 5 sites in France
- Volunteers
- 460 people
- Sponsor
- Hospices Civils de Lyon
Cervicogenic Headache, Proprioceptive Disorders
Manual Therapy vs. Multicomponent Exercise in Cervicogenic Headache
The purpose of this study is to compare the effects of manual therapy and a multicomponent exercise program on suboccipital muscle thickness, joint position sense, pain, central sensitization, balance, and kinesiophobia in…
- Conditions
- Cervicogenic Headache, Proprioceptive Disorders, Neck Pain Musculoskeletal
- Trial name
- NCT07776093
- Testing
- Manual Therapy Protocol, Multicomponent Exercise Program
- Volunteers
- 32 people
- Sponsor
- Pamukkale University
Post-Traumatic Respiratory Failure
Efficacy of Non-Invasive Mechanical Ventilation in Early Hypoxia Secondary to Thoracic Trauma
Severe post-traumatic hypoxia is mainly due to lung contusion. The intubation rate of these patients is near 20%. Treatment before intubation is needed, is based on pain control with epidural anesthesia and oxygen.
- Trial name
- NCT00557752
- Testing
- Non-invasive ventilation
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Virgen de la Salud
Intimate Partner Violence (IPV), Depression
Multi-component Family Intervention to Lower Depression and Address Intimate Partner Violence in Nepal
Intimate Partner Violence (IPV) is a major public health problem in low- and middle-income countries (LMICs). Globally, an estimated 30% of women report physical or sexual violence by an intimate partner in their lifetime.
- Conditions
- Intimate Partner Violence (IPV), Depression, PTSD - Post Traumatic Stress Disorder
- Trial name
- MILAP (NCT06834867)
- Testing
- MILAP intervention
- Where
- Nepal
- Volunteers
- 900 people
- Sponsor
- Possible
Concussion, Brain, Brain Injury Traumatic Mild
Concussion Health Improvement Program
More than 1 million U.S. youth sustain a concussion each year, and up to 30% report persistent post-concussive symptoms (PPCS) lasting 1 month or more.
- Trial name
- CHIP (NCT06036147)
- Testing
- Concussion-focused cognitive behavioral therapy, Parent skills training, Care management
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- Seattle Children's Hospital
Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries
Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury
The goal of this randomized clinical trial is to evaluate the effects of vibration on factors related to the risks of post-traumatic knee osteoarthritis and secondary anterior cruciate ligament (ACL) injury in individuals who…
- Conditions
- Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Quadriceps Muscle Atrophy
- Trial name
- NCT04875052
- Testing
- Experimental: Whole Body Vibration, Experimental: Local Muscle Vibration, Standard ACL Rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- University of North Carolina, Chapel Hill
Post Traumatic Stress Disorder, Depression
Cross-sectoral Collaboration in Multidisciplinary Treatment of Trauma-affected Refugees
INTRODUCTION Trauma-affected refugees are at high risk of developing mental health problems including post-traumatic stress disorder (PTSD) and depression.
- Conditions
- Post Traumatic Stress Disorder, Depression, Psychosocial Problem
- Trial name
- NCT04244864
- Testing
- Cross-sectoral psychosocial intervention, Treatment as usual (TAU)
- Where
- Denmark
- Volunteers
- 196 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Hematoma, Subdural, Chronic
Preventing Recurrences of Chronic Subdural Hematoma in Adult Patients by Middle Meningeal Artery Embolization
Patients with a chronic subdural hematoma (cSDH), that is, a blood accumulation between two meninges developing over a long period of time, often have recurrent bleedings after an initial operation.
- Trial name
- MEMBRANE (NCT05327933)
- Testing
- Surgery plus endovascular MMA embolization, Surgery alone
- Where
- Germany
- Volunteers
- 154 people
- Sponsor
- Unfallkrankenhaus Berlin
Adult Congenital Heart Disease, Congenital Heart Disease
Psychological Trauma, Post-Traumatic Stress Disorder, and Resilience in Adults With Congenital Heart Disease
The purpose of this study, entitled "Psychological trauma, post-traumatic stress disorder, and resilience in adults with congenital heart disease in a large population sample", is to evaluate for exposures during a lifetime with…
- Conditions
- Adult Congenital Heart Disease, Congenital Heart Disease, PTSD
- Trial name
- PTSD in ACHD (NCT06952933)
- Testing
- Other
- Where
- 3 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
PTSD
Neurofeedback Therapeutic Intervention For Post-Traumatic Stress Disorder Patients Compared To Treatment As Usual
Post-traumatic stress disorder (PTSD) is a common debilitating disorder that affects many individuals exposed to aversive events. The severity of PTSD symptoms is positively correlated with amygdala activation.
- Trial name
- NFTIP (NCT02544971)
- Testing
- Neurofeedback, Control
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Stress Disorders, Post-Traumatic
Transcendental Meditation and Reduced Trauma Symptoms in Women Inmates
The pilot study investigates the potential benefits of the Transcendental Meditation program in reducing trauma, including PTSD, in female prisoners.
- Trial name
- NCT02791464
- Testing
- Transcendental Meditation program
- Volunteers
- 22 people
- Sponsor
- Maharishi International University
Traumatic Brain Injury, Fatigue
Maximizing Energy After Traumatic Brain Injury
Traumatic brain injury (TBI) is the signature injury of the wars in Iraq and Afghanistan. Up to 73% of TBI patients endorse fatigue as their most challenging symptom.
- Trial name
- NCT04238910
- Testing
- Maximizing Energy, Health Education
- Volunteers
- 41 people
- Sponsor
- University of Pittsburgh
PTSD - Post Traumatic Stress Disorder
ONE-P TMS Military Veterans
The aim of this study is to examine the feasibility and tolerability of a one-day protocol of repetitive transcranial magnetic stimulation with D-cycloserine (DCS) as an augmentation strategy in military personnel and veterans…
- Trial name
- ONE-P (NCT07777380)
- Testing
- D-Cycloserine (DCS), Intermittent Theta Burst Stimulation (iTBS)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Fidel Vila-Rodriguez, MD, PhD, FRCPC, DFAPA
Posttraumatic Stress Disorder
Attentional Bias Modification in Patients With Posttraumatic Stress Disorder
Randomized, placebo-controlled trial of 9 sessions of computerized attentional bias training on attentional bias and on symptoms of Posttraumatic Stress Disorder.
- Trial name
- NCT00764101
- Testing
- Attentional Bias Modification
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- PsyQ
Stress Disorders, Post-Traumatic
IRT and CBT in Sexual Assault Victims With PTSD
Sexual assault victims (SAV) have an elevated risk of developing posttraumatic stress disorder (PTSD). Trauma-focused cognitive-behavioural therapy (CBT) is an effective first-line treatment for this pathology.
- Trial name
- NCT03169712
- Testing
- Cognitive Behavioral Therapy for PTSD, Imagery Rehearsal Therapy
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Laval University
Stress, Stress Disorder
The Professional Peer Resilience Initiative
The Professional Peer Resilience Initiative (PPRI) study is an observational study aimed at understanding how symptoms of traumatic stress and resilience evolve over time in the University of Minnesota (UMN) healthcare workforce…
- Conditions
- Stress, Stress Disorder, Stress, Psychological, Trauma, Psychological
- Trial name
- PPRI (NCT04396600)
- Testing
- MinnRAP Peer Support Program
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
PTSD
Yoga Online Feasibility to Reduce PTSD
Each year more than 26,000 pregnancies in the United States end in stillbirth (late fetal death at >20 weeks of gestation). A 2011 issue of the Lancet, dedicated entirely to stillbirth, recognized it as a "too-often-ignored"…
- Trial name
- NCT02925481
- Testing
- Moderate Online yoga participation, Stretching and toning, Low dose online yoga participation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Arizona State University
Concussion, Mild
Impact of a Paced Breathing Exercise Intervention on Autonomic Nervous System Function After Pediatric Concussion
The goal of this pilot clinical trial is to assess the feasibility of administering a paced breathing exercise intervention program to children and adolescents in the sub-acute period after concussion, and to document the…
- Trial name
- Breathe (NCT06559865)
- Testing
- Breathing exercises
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
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