Clinical trials: Postbiotics Supplementation
AMD, Soft Drusen
Study to Evaluate the Response to Supplementation With Postbiotics in Patients With Macular Degeneration.
A pilot study to establish the efficacy and safety of supplementation with postbiotics in patients with macular degeneration.
- Conditions
- AMD, Soft Drusen, Reticular Pseudodrusen, Drusen Stage Macular Degeneration
- Trial name
- REVERS (NCT05056025)
- Testing
- Postbotics and Vitamins, Vitamins
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Institut de la Macula y la Retina
Gastrointestinal Health
The Impact of Postbiotic Supplementation on Tolerability and Physiological/Metabolic Parameters
This study aimed to evaluate whether daily postbiotic supplementation could improve gastrointestinal well-being and influence physiological and metabolic parameters in healthy young adults.
- Trial name
- PIProBaTo-II (NCT07893301)
- Testing
- Postbiotic Supplement
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Federico II University
Childhood Obesity
Effect of POSTbiotics Supplementation on Microbiome in OBese Children: the POST-OB Study
This study evaluates the possible effect of postbiotics supplementation, combined with interventions aimed at improving diet and lifestyle, on gut microbiota composition and metabolite production.
- Trial name
- POST-OB (NCT04151823)
- Testing
- Vitamin D3, Immunofos, Promotion of physical activity
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Milan
Postbiotics Supplement
The Effect of Postbiotics Supplementation on Exercise-induced Oxidative Stress.
Scientific data on the effect of supplementation of postbiotics on exercise-induced oxidative stress are scarce. The main purpose of the research is to investigate the effect of postbiotics supplementation on exercise-induced…
- Trial name
- PB-EIOS (NCT06417671)
- Testing
- Postbiotics supplementation
- Where
- Greece
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Obesity, Obesity, Abdominal
Probiotic Lysate (Postbiotic and Metabiotic) Supplementation for Type 2 Diabetes Patients (DELI_Diab Study)
The current study aim was to conduct placebo-controlled randomize clinical trial to assess the short-term efficacy and safety of postbiotics as an adjunction to the standard anti-diabetic therapy on insulin resistance, glycemic…
- Conditions
- Obesity, Obesity, Abdominal, Insulin Resistance, Insulin Sensitivity
- Trial name
- NCT05770076
- Testing
- Probiotic lysate (postbiotic and metabiotic)
- Where
- 4 sites in Ukraine
- Volunteers
- 55 people
- Sponsor
- Bogomolets National Medical University
Oxidative Stress, Healthy
A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance
This is a prospective, randomized, placebo controlled, double-blind study to assess the effects of a postbiotic blend on exercise induced oxidative stress markers and exercise performance in healthy adult.
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness
- Trial name
- PBE (NCT06795425)
- Testing
- Postbiotic Active Lifestyle Blend
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Diabetes Mellitus, Type 2
Effect of a Postbiotic Intake on Glucose Control and Microbiota Composition of Type 2 Diabetic Subjects: a Randomized Controlled Trial.
The goal of this randomized clinical trial is to evaluate the effect of the administration of a postbiotic on glycemic control, insulin resistance and microbiota composition in subjects with type 2 diabetes.
- Trial name
- Diabet2Predict (NCT06448182)
- Testing
- Postbiotic
- Where
- 3 sites in Spain
- Volunteers
- 106 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Postbiotics Supplementation
Postbiotics Supplementation, Gut Microbiota Composition, and Exercise-induced Inflammation
This study will investigate the effect of postbiotics supplementation on gut microbiota (GM) composition, exercise-induced oxidative stress and performance following eccentrically biased exercise.
- Trial name
- PostBioExIn (NCT06428656)
- Testing
- Postbiotics supplementation
- Where
- Greece
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Non-Alcoholic Fatty Liver Disease, Non Alcoholic Fatty Liver
Probiotic Lysate (Postbiotic and Metabiotic) Supplementation for Adults NAFLD Patients (DELI_NAFLD Study)
The current study aim was to conduct placebo-controlled randomize clinical trial to assess the short-term efficacy and safety of postbiotics on hepatic fat content as measured by MRI-PDFF and ultrasonography, liver stiffness (LS)…
- Conditions
- Non-Alcoholic Fatty Liver Disease, Non Alcoholic Fatty Liver, Hepatic Steatosis, Fatty Liver
- Trial name
- NCT05804422
- Testing
- Probiotic lysate (postbiotic and metabiotc)
- Where
- 4 sites in Ukraine
- Volunteers
- 39 people
- Sponsor
- Bogomolets National Medical University
Hematologic Neoplasms, Gastrointestinal Symptoms
Effects of Synbiotic Supplementation on Gastrointestinal Symptoms, Appetite, and Nutritional Recovery in Patients After Autologous Bone Marrow Transplant
Patients undergoing autologous bone marrow transplantation (ABMT) receive high-dose chemotherapy and routine prophylactic antibiotics, which often disrupt the gut microbiome (dysbiosis).
- Conditions
- Hematologic Neoplasms, Gastrointestinal Symptoms, Malnutrition, Loss of Appetite
- Trial name
- NCT07845669
- Testing
- Tri-component Synbiotic Supplement
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Metabolic Dysfunction Associated Steatotic Liver Disease, Steatotic Liver Disease
Probiotic Lysate (Postbiotic and Metabiotic) Supplementation for Adults MASLD Patients (DELI_MASLD Study)
The current study aim was to conduct placebo-controlled randomize clinical trial to assess the short-term efficacy and safety of postbiotics on hepatic fat content as measured by biochemichal hepatic steatosis indeces, serum…
- Conditions
- Metabolic Dysfunction Associated Steatotic Liver Disease, Steatotic Liver Disease, Hepatic Steatosis
- Trial name
- NCT06352697
- Testing
- Probiotic lysate (postbiotic and metabiotc)
- Where
- 5 sites in Ukraine
- Volunteers
- 52 people
- Sponsor
- Bogomolets National Medical University
Diarrhoea of Diverse Aetiology Requiring Oral Rehydration Therapy, Diarrhoea and Gastrointestinal Symptoms Secondary to Enteral Nutrition
Medical Nutrition Formulations Enriched With Postbiotics for the Management of Gastrointestinal Disorders
Efficacy and tolerability of ABB i5 prebiotic and ABB C22 postbiotics for the management of constipation and gastrointestinal well-being: a pilot trial
- Trial name
- ABB S3/ABB C22 (NCT06738420)
- Testing
- ABB S3, ABB C22
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- AB Biotek