Clinical trials: Posterior Capsule Opacification
Posterior Capsule Opacification
Posterior Capsule Opacification and Optical Quality of Different Hydrophobic Acrylic Intraocular Lenses
The most frequent long-term complication of cataract surgery remains to be posterior capsule opacification (PCO). During the past decades many new intraocular lenses (IOL) with optimized lens material and design were introduced.
- Trial name
- NCT03831074
- Testing
- Implantation of an intraocular lenses: iMics 1 NY-60 & NY-60G
- Sponsor
- Medical University of Vienna
Cataract, Posterior Capsule Opacification
Two Different Cataract Surgical Procedures to Prevent Posterior Capsule Opacification
In this study, the investigators introduce a new "capsule-reserved" cataract surgical procedure in which anterior lens capsule is reserved and attached onto posterior lens capsule in the purpose of preventing posterior capsule…
- Trial name
- NCT02445274
- Testing
- Anterior lens capsule was reserved
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Sun Yat-sen University
Intraocular Lens Complication
Capsular Tension Ring With Hydeophilic Intraocular Lesnes to Decrease Posterior Capsule Opacification Versus Hydrophobic Ones
evaluate the clinical outcomes of routine CTR insertion in conjunction with hydrophilic versus hydrophobic IOLs following phacoemulsification.
- Trial name
- NCT06974578
- Testing
- phacoemulsification, CTR, hydrophilic IOL
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Posterior Capsule Opacification, Cataract
Comparison of the Effect of Hydrophobic Acrylic and Silicone 3-piece IOLs on Posterior Capsule Opacification
Age-related cataract is the main cause of impaired vision in the elderly population worldwide. The only treatment that can restore functional visual ability is cataract surgery where the opacified crystalline lens is removed by…
- Trial name
- NCT01936701
- Testing
- bilateral cataract surgery
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Cataract, Diabetes Mellitus Type 2
Role of Metformin in Posterior Capsule Opacification
Determination of concentrations of systemically applied metformin in human lens capsule and its ability to lower the proliferation rate of human lens epithelial cells in vitro.
- Trial name
- NCT07176338
- Testing
- Blood and lens capsule samples for PK testing
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Capsule Opacification, Ocular Hypertension
Prophylactic Use of Timolol Maleate to Prevent Intraocular Pressure Elevation After Nd:YAG Laser Posterior Capsulotomy
This randomized controlled trial evaluated whether a single drop of 0.5% timolol maleate, administered before neodymium-doped yttrium aluminium garnet (Nd:YAG) laser posterior capsulotomy, reduced the rise in intraocular pressure…
- Trial name
- NCT07729189
- Testing
- Timolol Maleate, No intervention
- Where
- Pakistan
- Volunteers
- 210 people
- Sponsor
- CMH Multan Institute of Medical Sciences
Posterior Capsule Opacification
An Innovative Method Fluid-jet to to Remove Residual Lens Fibers
Residual lens fibers (RLFs) on the posterior lens capsule during cataract surgery can cause after cataract, affecting visual quality and increasing the medical cost for further laser posterior capsulotomy.
- Trial name
- NCT03605160
- Testing
- traditional polish, fluid-jet
- Where
- China
- Volunteers
- 740 people
- Sponsor
- Sun Yat-sen University
Development of Posterior Capsule Opacification
Evaluation of Posterior Capsule Opacification in Eyes With Diabetes Mellitus
To compare the development of posterior capsule opacification (PCO) between eyes with and without a history of diabetes mellitus (DM) after single-piece hydrophobic acrylic intraocular lens (IOL) implantation 4 years…
- Trial name
- DM & PCO (NCT01480934)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Posterior Capsule Opacification, Pseudophakia
IOL Position and Refractive Change After Nd:YAG Laser Posterior Capsulotomy
After cataract surgery, the thin natural membrane that holds the artificial lens in place can slowly turn cloudy. This is called posterior capsule opacification. It makes vision blurry and can cause glare.
- Conditions
- Posterior Capsule Opacification, Pseudophakia, Refractive Errors
- Trial name
- YAG-IOL-POS (NCT07802145)
- Testing
- Nd:YAG laser posterior capsulotomy, Anterior segment swept-source OCT, Swept-source optical biometry
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Vienna Hospital Association
Posterior Capsule Opacification, Cataract
Posterior Capsule Opacification and Frequency of Nd:YAG Treatment and of Two IOLs: Hoya iMics Y-60H vs. Bausch&Lomb MI60 (MIMI)
Age-related cataract is the main cause of impaired vision in the elderly population worldwide. The only treatment that can restore functional visual ability is cataract surgery where the opacified crystalline lens is removed by…
- Trial name
- NCT01786356
- Testing
- HOYA iMics Y-60H, B&L MI60
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Cataract
Influence of Two Different Preloaded Intraocular Lens (IOLs) on Posterior Capsule Opacification
Studies showed that a sharp posterior optic edge of an intraocular lens (IOL) inhibits migration of lens epithelial cells in between posterior capsule and optic of the IOL and therefore reduces the rate of posterior capsule…
- Trial name
- NCT00673803
- Testing
- cataract surgery
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Hospital Hietzing
Capsule Opacification, Pseudophakia
Posterior Capsule Opacification and Frequency of Nd:YAG Treatment and of Two Microincision IOLs: Hoya iMics NY-60 vs Acrysof SN60WF
Age-related cataract is the main cause of impaired vision in the elderly population worldwide. In the UK, more than half of people who are over 65 have some cataract development in one or both eyes.
- Conditions
- Capsule Opacification, Pseudophakia, Cataract
- Trial name
- NCT01732484
- Testing
- intraocular lens implantation
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Posterior Capsule Opacification
Refraction Changes After Using ND: YAG LASER In Treatment of Posterior Capsular Opacification In Pseudo Phakic Eye
The most prevalent long term consequence of cataract surgery in both phacoemulsification and extracapsular cataract excision is posterior capsular opacification (PCO) PCO occurred in 11.8 percent of patients one year after…
- Trial name
- NCT05501535
- Testing
- ND:YAG LASER
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Blindness
Pars Plana Surgical Capsulotomy for Posterior Capsular Opacification
Cataract is a leading cause of Global blindness. After cataract surgery nearly half of the people become blind due to posterior capsular opacification. The only solution for this problem is LASER capsulotomy.
- Trial name
- Capsulotomy (NCT00964613)
- Volunteers
- 176 people
- Sponsor
- Dow University of Health Sciences
Cataract
Glistenings and PCO Evaluation for the Envista MX60
Posterior capsule opacification (PCO) and glistenings development is among the primary reasons for sub-optimal visual capacity following cataract extraction surgery.
- Trial name
- NCT02698943
- Testing
- Phacoemulsification
- Volunteers
- 60 people
- Sponsor
- Democritus University of Thrace
Capsule Opacification, Pseudophakia
Posterior Capsule Opacification and Frequency of Nd:YAG Treatment and of Two Microincision IOLs: Tecnis ZCB00 and Acrysof SA60AT
Age-related cataract is the main cause of impaired vision in the elderly population worldwide. In the UK, more than half of people who are over 65 have some cataract development in one or both eyes.
- Conditions
- Capsule Opacification, Pseudophakia, Cataract
- Trial name
- NCT01742910
- Testing
- intraocular lens implantation
- Where
- Austria
- Volunteers
- 54 people
- Sponsor
- Medical University of Vienna
Posterior Capsule Opacification
Posterior Capsule Opacification (PCO) With AcrySof Single-Piece IOL
The purpose of this study what to evaluate if axial myopia might influence the development of PCO.
- Trial name
- NCT00855491
- Testing
- Phaco
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract
Posterior Capsule Opacification (PCO) Evaluation of the AcrySof SN60AT Lens vs. SN60WF Lens
To assess posterior capsule opacification (PCO) in patients implanted with either the AcrySof SN60AT lens or the AcrySof SN60WF lens.
- Trial name
- NCT00762021
- Testing
- SN60AT, SN60WF
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Alcon Research
Dysphotopsia, Posterior Capsule Opacification
Clinical Evaluation of Low Contrast Visual Performance and Low Light Phenomena in Patients With Various Intraocular Lens Implants
The goal of this clinical investigation is to evaluate visual acuity and contrast sensitivity in low lighting conditions using several different testing devices, and measure nighttime side effects of intraocular lens (IOL)…
- Conditions
- Dysphotopsia, Posterior Capsule Opacification, Visual Acuity, Visual Function
- Trial name
- NCT07213167
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Dr. Daniel H. Chang, MD
Cataract
Posterior Capsule Opacification Study
First object is to compare square edge PMMA with round edge PMMA IOL where the materials are same. Next objective is to compare square edge PMMA IOL with Acrysof IOL where the materials are different
- Trial name
- NCT00312299
- Testing
- Square edge PMMA IOL, Round edge PMMA IOL, Acrysof IOL
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Aurolab