Clinical trials: Posterior Lumbar Interbody Fusion (PLIF)
Lumbar Degenerative Disease
Unilateral Biportal Endoscopy Lumbar Interbody Fusion (ULIF) Versus Posterior Lumbar Interbody Fusion (PLIF) in Management of Single Level Lumbar Degenerative Disease: A Retrospective Study
The study aimed to compare the clinical efficacy and safety of unilateral biportal endoscopic lumbar interbody fusion (ULIF) with posterior lumbar interbody fusion (PLIF) in the treatment of single-level lumbar degenerative…
- Trial name
- NCT06506500
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Lumbar Spondylolisthesis
Comparative Study Between Posterior Lumbar Interbody Fusion(PLIF) and Intertransverse Process Fusion in Treatment of Spodylolithesis
The first technique described for interbody fusion was the anterior lumbar interbody fusion (ALIF).(20) For this technique, the intervertebral disc is accessed through a retroperitoneal or transperitoneal approach.
- Trial name
- NCT03271060
- Testing
- Posterior lumbar interbody fusion, Inter transverse bone grafting
- Volunteers
- 30 people
- Sponsor
- Assiut University
Blood Loss, Surgical
Effect of Equal Ratio Ventilation on Blood Loss During Posterior Lumbar Interbody Fusion Surgery
Ventilator mode change was associated with decrease in blood loss during posterior lumbar interbody fusion (PLIF) due to decrease in the peak inspiratory pressure (PIP).
- Trial name
- NCT03030963
- Testing
- Equal ratio ventilation(ERV), I:E Ratio "1:2
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Degenerative Disc Disease
Trinity Evolution in Posterior or Transforaminal Lumbar Interbody Fusion (PLIF/TLIF)
The purpose of this study is to utilize Trinity Evolution in conjunction with an interbody spacer and supplemental posterior fixation of the surgeon's choice and to follow the patients to measure the clinical outcomes and rate of…
- Trial name
- TLF (NCT00965380)
- Where
- 15 sites in United States
- Volunteers
- 207 people
- Sponsor
- Orthofix Inc.
Spondylosis, Cervical Spondylosis
ViBone in Cervical and Lumbar Spine Fusion
Assess clinical and radiographic outcomes in patients who undergo 1-3 level anterior cervical discectomy fusion (ACDF) or lumbar interbody fusion (TLIF, PLIF, ALIF, or LLIF) using ViBone.
- Conditions
- Spondylosis, Cervical Spondylosis, Spondylolisthesis, Herniated Nucleus Pulposus
- Trial name
- NCT03425682
- Testing
- ViBone
- Where
- 4 sites in United States
- Volunteers
- 118 people
- Sponsor
- Elutia Inc.
Degenerative Lumbar Spine Diseases
Assessing Risk Factors for Radiological Complications After Transforaminal Lumbar Interbody Fusion
This retrospective study is to determine whether age is a risk factor for postoperative complications in patients undergoing transforaminal lumbar interbody fusion; specifically whether the risk (odds) of implant failure and the…
- Trial name
- AgeTLIF (NCT05266638)
- Testing
- Data collection (radiological parameters, outcome information) from electronic patient files in hospital data system
- Where
- Switzerland
- Volunteers
- 170 people
- Sponsor
- University Hospital, Basel, Switzerland
Fusion of Spine (Disease)
The Effectiveness of Vitamin C in Postoperative Pain Management of Single-level Posterior Lumbar Interbody Fusion (PLIF)
Postoperative pain management remains a major challenge for surgeons. Despite huge technological advances in pain management, many researchers have documented that unrelieved pain remains common after surgeries, which is…
- Trial name
- NCT02127060
- Testing
- Vitamin C
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Seoul National University Hospital
Lumbar Degenerative Disc Disease
Radiographic and Clinical Outcomes of PureGen in Posterior Lumbar (PLIF) and Transforaminal Interbody Fusion (TLIF)
The purpose of this study is to assess the safety and efficacy of PureGen Osteoprogenitor Cell Allograft in patients undergoing Posterior Lumbar or Transforaminal Interbody Fusion.
- Trial name
- NCT01293981
- Testing
- PureGen Osteoprogenitor Cell Allograft
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Alphatec Spine, Inc.
Double Level Lumbar Spondylolisthesis (L3-L5), Posterior Lumbar Interbody Fusion (PLIF)
Effect of Addition of Dexmedetomidine During Ultrasound Guided Bilateral Single Shot Erector Spinae Plane Block in Patients Undergoing Posterior Lumbar Interbody Fusion Under General Anesthesia
Posterior lumbar interbody fusion (PLIF) is the management of choice in double level lumbar (L) spondylolisthesis (L3-L5) after ineffective conservative treatment.
- Conditions
- Double Level Lumbar Spondylolisthesis (L3-L5), Posterior Lumbar Interbody Fusion (PLIF), Lumbar Fixation Surgery
- Trial name
- NCT03746418
- Testing
- Ultrasound Guided Bilateral single shot Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tanta University
Degenerative Disc Disease
Osteocel® Plus in Posterior Lumbar Interbody Fusion (PLIF)
This study is being conducted to determine the percentage of patients with solid spinal fusions after being treated with Osteocel Plus in a PLIF procedure.
- Trial name
- NCT00941980
- Testing
- Osteocel Plus
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- NuVasive
Posterior Lumbar Interbody Fusion (PLIF), Postoperative Analgesia After Disc Surgery
Comparing Long-Acting Local Pain Relief Methods in PLIF Surgery
This study is being done to compare three ways of using long-acting local pain medicine around the surgical wound during open lumbar fusion surgery.
- Trial name
- NCT07919275
- Testing
- Liposomal Bupivacaine (EXPAREL®)/Bupivacaine, Standard Analgesic Cocktail, Modified Analgesic Cocktail
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Muscle Damage, Atrophy
Extreme Lateral Interbody FusionFUSION (XLIF) Versus Posterior Lumbar Interbody Fusion (PLIF)
Since the first successful spinal fusion surgery using a modern stabilization technique in 1909, surgical fusion has become one of the most commonly performed procedures for degenerative disease of the lumbar spine.
- Conditions
- Muscle Damage, Atrophy, Degenerative Diseases, Spinal Cord
- Trial name
- XLIF (NCT04589572)
- Testing
- XLIF, PLIF
- Where
- 3 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- Hasselt University