Clinical trials: Postmenopausal Osteopenia
Osteoporosis, Osteopenia
Texture Analysis for Postmenopausal Osteoporosis
The purpose of this study is to determine if a new test for osteoporosis can be useful in monitoring treatment. We are studying a new method for examining the quality of bone by an experimental method of computerized analysis of…
- Trial name
- NCT00145977
- Testing
- Alendronate, Calcium Citrate, Vitamin D
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Chicago
Bone Diseases, Metabolic, Osteoporosis, Postmenopausal
The Effects of Potassium Citrate on Bone Metabolism
Skeletal buffering of chronic acid loads may contribute to a significant amount of bone loss over time. Evidence from a few small short-term studies suggests that basic compounds, namely potassium citrate and potassium…
- Trial name
- NCT00357331
- Testing
- potassium citrate
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Postmenopausal Osteoporosis
A Trial Evaluating Efficacy of AGA2118 in PostMenopausal Women wIth Low Bone MasS (ARTEMIS)
The primary objective of this study is to determine the effect of treatment with AGA2118 versus placebo at Month 12 on lumbar spine bone mineral density (BMD) in postmenopausal women with low bone mass.
- Trial name
- ARTEMIS (NCT06577935)
- Testing
- AGA2118
- Where
- 23 sites in United States, Argentina and 2 more
- Volunteers
- 379 people
- Sponsor
- Angitia Biopharmaceuticals
Low Bone Density, Osteopenia
Safety and Pharmacokinetics of Orally Administered Strontium L-Lactate in Healthy Adults
No clinical trials have evaluated strontium L-lactate (SrLac), the strontium salt of the L-enantiomer of lactic acid. Therefore, this clinical study was conducted to obtain general safety and pharmacokinetic (PK) information…
- Conditions
- Low Bone Density, Osteopenia, Osteoporosis, Postmenopausal
- Trial name
- NCT03761979
- Testing
- Strontium L-lactate
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- BioLink Life Sciences, Inc.
Osteopenia
A First-in-human Study Evaluating Romosozumab (AMG 785) in Healthy Men and Postmenopausal Women
The primary objective of this study is to assess the safety and tolerability of romosozumab following single dose subcutaneous (SC) or intravenous (IV) administration in healthy men and postmenopausal women.
- Trial name
- NCT01059435
- Testing
- Romosozumab
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Amgen
Perimenopausal Bone Loss
Prunes Preventing Bone Loss in Perimenopause
Dietary interventions of prune consumption during the transmenopausal period are innovative methods to prevent bone loss. Modern medicine does not intervene to prevent or attenuate this highly vulnerable period of bone loss…
- Trial name
- Prune-UP (NCT07120997)
- Testing
- Prunes, Calcium supplement, Vitamin D Supplement
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Penn State University
Bone Disease, Metabolic
Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal Women
The objective of this study is to examine if calcium and vitamin D supplements and/or prune can prevent bone loss in postmenopausal women.
- Trial name
- NCT06184646
- Testing
- Prune
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- San Diego State University
Post-Menopausal Osteoporosis, Post-Menopausal Osteopenia
Vitamin K Supplementation in Post-Menopausal Osteopenia
The purpose of this study is to determine whether supplementation with 5 mg vitamin K daily over a 2-year period will prevent bone loss in post-menopausal women with osteopenia.
- Trial name
- NCT00150969
- Testing
- vitamin K1 (phylloquinone)
- Where
- 5 sites in Canada
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Postmenopausal Osteoporosis
VERtebral Fracture Treatment Comparisons in Osteoporotic Women
The primary purpose of participation in this study is to answer whether teriparatide is superior to risedronate in reducing the occurrence of new vertebral fractures during 24 months of therapy.
- Trial name
- VERO (NCT01709110)
- Testing
- Teriparatide, Risedronate, Calcium
- Where
- 103 sites in United States, Argentina and 13 more
- Volunteers
- 1,366 people
- Sponsor
- Eli Lilly and Company
Osteopenia
A Study to Evaluate the Effect of Romosozumab (AMG 785) on Bone Quality of the Forearm in Postmenopausal Women With Low Bone Mass
The purpose of this study is to evaluate the effect of romosozumab on parameters of bone quality of the forearm using peripheral quantitative computed tomography (pQCT) following multiple subcutaneous dose administrations of…
- Trial name
- NCT00950950
- Testing
- Romosozumab
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Amgen
Metabolic Syndrome, Fall Risk
Physical Activity and Disability Prevention in Postmenopausal Women
The aim of this clinical study is to examine the impact of physical activity on the physical and mental health of postmenopausal women, with a particular focus on the development of disability.
- Conditions
- Metabolic Syndrome, Fall Risk, Sarcopenia in Elderly, Osteopenia, Osteoporosis
- Trial name
- PADP-Women (NCT06781541)
- Testing
- Nordic walking, Strength training, Bungy Pump Exercises
- Where
- Poland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Postmenopausal Osteopenia
Effects of Kinect-based Virtual Reality Training in Postmenopausal Women With Osteopenia
Osteopenia is a clinical term to define the declined Bone Mineral Density (BMD) as per the normal reference values but not low enough to meet osteoporotic diagnostic criteria.
- Trial name
- NCT04862910
- Testing
- Kinect Based Virtual Reality Training, Control Group
- Where
- 2 sites in Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Osteopenia, Osteoporosis
Feasibility of a Novel Resistance Exercise in Individuals With Osteoporosis
The aim of the 2 month randomized controlled trial is to investigate the feasibility of a novel progressive muscle resistance exercise in individuals with low bone mass.
- Conditions
- Osteopenia, Osteoporosis, Postmenopausal Osteoporosis, Sarcopenia
- Trial name
- NCT05060380
- Testing
- Exercise training
- Sponsor
- University of Alabama at Birmingham
Osteoporosis, Osteopenia, Osteoporosis, Postmenopausal
Effects of Vitamin D Supplementation in Muscle Strength and Balance Training
Introduction: In Brazil, a person who is sixty years old or more is considered elderly. The incidence of osteoporosis and osteopenia has been increasing, as have fractures resulting from falls.
- Trial name
- NCT03367585
- Testing
- Physical exercise + Vitamin D3, Physical exercise
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- University of Sao Paulo General Hospital
Osteoporosis
Safety/Efficacy of Zoledronic Acid and Alendronate on Bone Metabolism in Postmenopausal Women With Osteoporosis
The aim of this study was to examine the effect of zoledronic acid and alendronate on bone metabolism as measured by biomarkers in postmenopausal women with osteoporosis.
- Trial name
- ROSE (NCT00404820)
- Testing
- Zoledronic acid 5 mg solution, Alendronate 70 mg tablets, Calcium/Vitamin D
- Where
- Germany
- Volunteers
- 604 people
- Sponsor
- Novartis
Osteopenia
Osteoporosis Prevention With Low Dose Alendronate
The purpose of this study is to evaluate the efficacy of the intermittent administration of alendronate in a low dose, 70 mg once every two week, as osteoporosis prevention for menopausal, osteopenic patients, who don't want or…
- Trial name
- NCT00463268
- Testing
- alendronate, Calcium/Vitamin D
- Where
- Belgium
- Volunteers
- 83 people
- Sponsor
- University Hospital of Mont-Godinne
Osteoporosis, Osteopenia
Investigating the Effect of Standardized Olive Extract on Bone Turnover Markers in Postmenopausal Women
The purpose of this study is to determine whether the intake of a daily dosage of standardized olive extract provides any protection against bone loss.
- Trial name
- NCT00789425
- Testing
- Standardized Extract of Olive Polyphenols
- Where
- Poland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- BioActor
Osteoporosis
Safety and Efficacy of AAE581 in Postmenopausal Women With Osteoporosis
This study will test the safety and efficacy of AAE581 in increasing Lumbar Spine bone mineral density (BMD) at 12 months, by Dexa-scan (DXA) in postmenopausal women with osteoporosis.
- Trial name
- NCT00100607
- Testing
- AAE581
- Volunteers
- 676 people
- Sponsor
- Novartis Pharmaceuticals
Osteoporosis, Osteopenia, Osteoporosis
Intervention Study of Drugs in Patients Osteopenia and Osteoporosis
This is a 12 months, randomized, multicenter, open-label, parallel-group study in postmenopausal women and male aged 50 years or old with osteoporosis or osteopenia in China to evaluate the efficacy and safety of different…
- Trial name
- NCT04719572
- Testing
- Basic treatment group, Basic treatment+ anti-osteoporosis drug group, Basic treatment + non-drug treatment group
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Chinese PLA General Hospital
Osteoporosis, Postmenopausal, Osteopenia
Validation, Reliability and Pilot Test of the Personalized Exercise Questionnaire (PEQ)
The PEQ is the first tool to measure facilitators, barriers, and preferences to exercise in people with osteoporosis.
- Trial name
- NCT03125590
- Testing
- Testing the PEQ (Personalized Exercise Questionnaire)
- Where
- Canada
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- McMaster University